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The map label for this gene is oprJ [H]

Identifier: 66768096

GI number: 66768096

Start: 2159468

End: 2160979

Strand: Direct

Name: oprJ [H]

Synonym: XC_1775

Alternate gene names: 66768096

Gene position: 2159468-2160979 (Clockwise)

Preceding gene: 66768095

Following gene: 66768097

Centisome position: 41.94

GC content: 71.16

Gene sequence:

>1512_bases
TTGCAATGCACTGATTCCCTGCGCCTGGCGCGCATGCCGCTGGCGGCAGCGCTGGCCTCACTGCTGCTGGGCGGCTGCAT
GCTCGGCCCCAACTACACCAAGCCGCCCGCGGTGGCCGAAACCGCCGTGCAGGCGCCCACGCTGCATCGCGCCAGTGCGG
CCGATGTGGTCGCCGCCGCACCACTGAATCACTGGTGGGAAGACCTGCGCGATGCGCAGCTGACCCAGCTCGTCACTCAG
GCCCTGGCCGACAGCCCCAACCTGCGCGCAGCGCAGGCGCGTCTGCGCGCCAATCGGGCGCTGGCCAACCAGCGCCGTGC
CGAGCGGCTGCCCAAGCTCAACGCCAGTGCGCTGTACGCCTATGCCGAGCCGCCGCAGACCATCGTCGACACCCTGGGCG
GGCTGCAGAACGGCCAGCAGGGCCAGCCGCCGGCGCAGGGCAGCCAGGCGCTGAACCTGGAAAAGACCGAGCTCTACACC
GCCGGCTTCGATGCCAGCTGGGAGCTGGACCTGTTCGGCCGCCGCCGCCGCGCCGCCGAAGGCGCGCTGGCCCAGGCGCA
GGCGTCCGAAGCCGAACTGGCCGACGCGCAGGTGCAGCTGGCTGCCGAAGTGGGGCAGGTCTATCTCAACTACCGCGGGT
TGCAGGCGCGCCTGGCGATTGCCGACAGCAACCTGGACAAGATCCGTCAGTCGCTGGCCCTGGTGCAGCAGCGCCGCGGC
CAGGGTGCCGCCTCGGACCTGCAGGTCGAGCAGATCGCCACCCAGGTGCAGCAGCAGCAGGCCCAGCGCCTGCCGCTGCA
GATGCAGCAACAGGAAGCGCTGGACCAGCTGGCGTTGATGGTCGGCCGCGAGCCGGGCGCGCTGGATGCGCAGCTCGCCG
CGCCGCAACCGCTGCCGATGCTGCCCACCCAGGTGCGCGTGGACGATGCCGGTGCGTTGATCCGTCGGCGCCCGGACGTG
CGCAAGGCCGAGCGCGAGCTGGCCGCGTCCAGTGCGCAGATCGGCGAGGCGTTGAATGGCTACTTCCCGCAGGTCAGCCT
GCTTGGCGGCCTGAGCTGGGTGGCCGGCTCGCCCAGCGATTTCAATTCCGATGCGCTGACCAAGCTGGCAGTGCCGATGC
TGCGCTGGTCGATCTTCGACTTCGGCCGCACCCGCGCGCAGGTCGAACAGGCGCGTGCCGGCAATGCCGGGCGCGAGGCC
GCCTATGAAGGTGCGGTGCTGGCGGCGCTGCAGGACGCCAATACCGCACTGTCGCGGTTTGGCTCGGCACGCCAGCAACT
GGTGGTAGCGCGGCAGGCCGAGGCCTCGGCCACGCGCTCTGCCGGGCTCATGCAGCAGCGCCGCGATGCCGGTGCCACCT
CCAGCATCGACCTGCTCGATGTGCAGCGCCAGCAGTTGTCCGCGCAGGACGCCGCCGCGCAGGCGCAGGTGCAATTGCTG
GTGTATTACGTGGCGCTGCAGAAGAGCCTGGGCCTGGGCTGGAGCGAGCCGCCGCAGGCCGCCGCCCGCTAG

Upstream 100 bases:

>100_bases
GTGATGACCTATAGCGACCTGTTCTGGATCTTTGGCGTGATCGTGGTCTGCACGATTCCGCTGGCCTTTTTGCTCAAGCC
GTTACCCAAGGGGACGCACC

Downstream 100 bases:

>100_bases
AGCCACGCGTGTCGGCGCGCACTGTAGCGCCGGCACGCTTTTGCCATGATGCGTGTACGGCGCCACGGTGGCGCCGGCGC
GTTGTTGTCACCGAGAGGAT

Product: outer membrane protein OprN precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MQCTDSLRLARMPLAAALASLLLGGCMLGPNYTKPPAVAETAVQAPTLHRASAADVVAAAPLNHWWEDLRDAQLTQLVTQ
ALADSPNLRAAQARLRANRALANQRRAERLPKLNASALYAYAEPPQTIVDTLGGLQNGQQGQPPAQGSQALNLEKTELYT
AGFDASWELDLFGRRRRAAEGALAQAQASEAELADAQVQLAAEVGQVYLNYRGLQARLAIADSNLDKIRQSLALVQQRRG
QGAASDLQVEQIATQVQQQQAQRLPLQMQQQEALDQLALMVGREPGALDAQLAAPQPLPMLPTQVRVDDAGALIRRRPDV
RKAERELAASSAQIGEALNGYFPQVSLLGGLSWVAGSPSDFNSDALTKLAVPMLRWSIFDFGRTRAQVEQARAGNAGREA
AYEGAVLAALQDANTALSRFGSARQQLVVARQAEASATRSAGLMQQRRDAGATSSIDLLDVQRQQLSAQDAAAQAQVQLL
VYYVALQKSLGLGWSEPPQAAAR

Sequences:

>Translated_503_residues
MQCTDSLRLARMPLAAALASLLLGGCMLGPNYTKPPAVAETAVQAPTLHRASAADVVAAAPLNHWWEDLRDAQLTQLVTQ
ALADSPNLRAAQARLRANRALANQRRAERLPKLNASALYAYAEPPQTIVDTLGGLQNGQQGQPPAQGSQALNLEKTELYT
AGFDASWELDLFGRRRRAAEGALAQAQASEAELADAQVQLAAEVGQVYLNYRGLQARLAIADSNLDKIRQSLALVQQRRG
QGAASDLQVEQIATQVQQQQAQRLPLQMQQQEALDQLALMVGREPGALDAQLAAPQPLPMLPTQVRVDDAGALIRRRPDV
RKAERELAASSAQIGEALNGYFPQVSLLGGLSWVAGSPSDFNSDALTKLAVPMLRWSIFDFGRTRAQVEQARAGNAGREA
AYEGAVLAALQDANTALSRFGSARQQLVVARQAEASATRSAGLMQQRRDAGATSSIDLLDVQRQQLSAQDAAAQAQVQLL
VYYVALQKSLGLGWSEPPQAAAR
>Mature_503_residues
MQCTDSLRLARMPLAAALASLLLGGCMLGPNYTKPPAVAETAVQAPTLHRASAADVVAAAPLNHWWEDLRDAQLTQLVTQ
ALADSPNLRAAQARLRANRALANQRRAERLPKLNASALYAYAEPPQTIVDTLGGLQNGQQGQPPAQGSQALNLEKTELYT
AGFDASWELDLFGRRRRAAEGALAQAQASEAELADAQVQLAAEVGQVYLNYRGLQARLAIADSNLDKIRQSLALVQQRRG
QGAASDLQVEQIATQVQQQQAQRLPLQMQQQEALDQLALMVGREPGALDAQLAAPQPLPMLPTQVRVDDAGALIRRRPDV
RKAERELAASSAQIGEALNGYFPQVSLLGGLSWVAGSPSDFNSDALTKLAVPMLRWSIFDFGRTRAQVEQARAGNAGREA
AYEGAVLAALQDANTALSRFGSARQQLVVARQAEASATRSAGLMQQRRDAGATSSIDLLDVQRQQLSAQDAAAQAQVQLL
VYYVALQKSLGLGWSEPPQAAAR

Specific function: Channel-forming component of a multidrug resistance efflux pump [H]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=490, Percent_Identity=26.1224489795918, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI2367348, Length=512, Percent_Identity=24.609375, Blast_Score=76, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53918; Mature: 53918

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCTDSLRLARMPLAAALASLLLGGCMLGPNYTKPPAVAETAVQAPTLHRASAADVVAAA
CCCCHHHHHHHCCHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHH
PLNHWWEDLRDAQLTQLVTQALADSPNLRAAQARLRANRALANQRRAERLPKLNASALYA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
YAEPPQTIVDTLGGLQNGQQGQPPAQGSQALNLEKTELYTAGFDASWELDLFGRRRRAAE
ECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHEEEECCCCCEEEHHHHHHHHHHH
GALAQAQASEAELADAQVQLAAEVGQVYLNYRGLQARLAIADSNLDKIRQSLALVQQRRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCC
QGAASDLQVEQIATQVQQQQAQRLPLQMQQQEALDQLALMVGREPGALDAQLAAPQPLPM
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
LPTQVRVDDAGALIRRRPDVRKAERELAASSAQIGEALNGYFPQVSLLGGLSWVAGSPSD
CCCEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHCCCCCC
FNSDALTKLAVPMLRWSIFDFGRTRAQVEQARAGNAGREAAYEGAVLAALQDANTALSRF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHH
GSARQQLVVARQAEASATRSAGLMQQRRDAGATSSIDLLDVQRQQLSAQDAAAQAQVQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VYYVALQKSLGLGWSEPPQAAAR
HHHHHHHHHHCCCCCCCCHHCCC
>Mature Secondary Structure
MQCTDSLRLARMPLAAALASLLLGGCMLGPNYTKPPAVAETAVQAPTLHRASAADVVAAA
CCCCHHHHHHHCCHHHHHHHHHHCCHHCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHH
PLNHWWEDLRDAQLTQLVTQALADSPNLRAAQARLRANRALANQRRAERLPKLNASALYA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
YAEPPQTIVDTLGGLQNGQQGQPPAQGSQALNLEKTELYTAGFDASWELDLFGRRRRAAE
ECCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHEEEECCCCCEEEHHHHHHHHHHH
GALAQAQASEAELADAQVQLAAEVGQVYLNYRGLQARLAIADSNLDKIRQSLALVQQRRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHCC
QGAASDLQVEQIATQVQQQQAQRLPLQMQQQEALDQLALMVGREPGALDAQLAAPQPLPM
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
LPTQVRVDDAGALIRRRPDVRKAERELAASSAQIGEALNGYFPQVSLLGGLSWVAGSPSD
CCCEEEECCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCHHHHCCCCCC
FNSDALTKLAVPMLRWSIFDFGRTRAQVEQARAGNAGREAAYEGAVLAALQDANTALSRF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHH
GSARQQLVVARQAEASATRSAGLMQQRRDAGATSSIDLLDVQRQQLSAQDAAAQAQVQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VYYVALQKSLGLGWSEPPQAAAR
HHHHHHHHHHCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8878035; 10984043 [H]