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The map label for this gene is infC [H]

Identifier: 66767975

GI number: 66767975

Start: 1987352

End: 1987831

Strand: Direct

Name: infC [H]

Synonym: XC_1651

Alternate gene names: 66767975

Gene position: 1987352-1987831 (Clockwise)

Preceding gene: 66767974

Following gene: 66767976

Centisome position: 38.6

GC content: 59.79

Gene sequence:

>480_bases
GTGCCGCGCGTTCGCGTGATCGGTAGTGACGGTGAGATGGTCGGCGTGTTGTCGCGCGACGAAGCGCTCGCCAAGGCCGA
GGAAGAAGGCCTGGATCTGGTCGAAATCCAGCCGCAGGCCGATCCGCCGGTCTGCAAGATCATGGATTTCGGCAAGTTCA
AGTTCGAGCAGCAGAAAAAGGCCAACGAGGCCAAGAAGAAGACCAAGCAGGTCGAGATCAAGGAACTCAAGTTCCGTCCG
GTCACGGACGAGGGCGACTACCAGATCAAGCTGCGCAACATGCGCCGTTTCCTGGAAGAGGGTGACAAGGTCAAGGTCAA
CATCCGTTTCCGTGGCCGCGAAATGAGCCACCAGGAACTGGGCCGCGAGATGGCGGCACGGATCGAGGCCGATCTGGGCG
AAGACATTGTCATCGAGTCCCGTCCGCGCCTGGAAGGGCGGCAGATGGTCATGATGATCGCGCCCAAGAAGAAGATCTGA

Upstream 100 bases:

>100_bases
CCGGTCTGGATGATCCGGATGCGCCGGTTCGATTCCCCTGGGAGATTGCAATATCAGTACCCCTGACAACAAACAGAACC
GCAAGAACCAAGAAATCCGT

Downstream 100 bases:

>100_bases
TCCTGCGCCGCGGCGGGCCCGAGAGGGGCCGCCCAGGCGGCGACAGCGACGATTTGCAAGAATTCCCGGCAACGGGCATA
CTGCGCGGCCCGGTTTTGCC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MPRVRVIGSDGEMVGVLSRDEALAKAEEEGLDLVEIQPQADPPVCKIMDFGKFKFEQQKKANEAKKKTKQVEIKELKFRP
VTDEGDYQIKLRNMRRFLEEGDKVKVNIRFRGREMSHQELGREMAARIEADLGEDIVIESRPRLEGRQMVMMIAPKKKI

Sequences:

>Translated_159_residues
MPRVRVIGSDGEMVGVLSRDEALAKAEEEGLDLVEIQPQADPPVCKIMDFGKFKFEQQKKANEAKKKTKQVEIKELKFRP
VTDEGDYQIKLRNMRRFLEEGDKVKVNIRFRGREMSHQELGREMAARIEADLGEDIVIESRPRLEGRQMVMMIAPKKKI
>Mature_158_residues
PRVRVIGSDGEMVGVLSRDEALAKAEEEGLDLVEIQPQADPPVCKIMDFGKFKFEQQKKANEAKKKTKQVEIKELKFRPV
TDEGDYQIKLRNMRRFLEEGDKVKVNIRFRGREMSHQELGREMAARIEADLGEDIVIESRPRLEGRQMVMMIAPKKKI

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=156, Percent_Identity=60.2564102564103, Blast_Score=182, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 18371; Mature: 18240

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRVRVIGSDGEMVGVLSRDEALAKAEEEGLDLVEIQPQADPPVCKIMDFGKFKFEQQKK
CCCEEEECCCCCEEEEECCCHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCCCHHHHHH
ANEAKKKTKQVEIKELKFRPVTDEGDYQIKLRNMRRFLEEGDKVKVNIRFRGREMSHQEL
HHHHHHHHHCCEEEHEEEEECCCCCCEEEEHHHHHHHHHCCCEEEEEEEECCCCCCHHHH
GREMAARIEADLGEDIVIESRPRLEGRQMVMMIAPKKKI
HHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure 
PRVRVIGSDGEMVGVLSRDEALAKAEEEGLDLVEIQPQADPPVCKIMDFGKFKFEQQKK
CCEEEECCCCCEEEEECCCHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCCCHHHHHH
ANEAKKKTKQVEIKELKFRPVTDEGDYQIKLRNMRRFLEEGDKVKVNIRFRGREMSHQEL
HHHHHHHHHCCEEEHEEEEECCCCCCEEEEHHHHHHHHHCCCEEEEEEEECCCCCCHHHH
GREMAARIEADLGEDIVIESRPRLEGRQMVMMIAPKKKI
HHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]