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The map label for this gene is virB3 [H]

Identifier: 66767962

GI number: 66767962

Start: 1963989

End: 1964300

Strand: Direct

Name: virB3 [H]

Synonym: XC_1638

Alternate gene names: 66767962

Gene position: 1963989-1964300 (Clockwise)

Preceding gene: 66767961

Following gene: 66767963

Centisome position: 38.15

GC content: 50.0

Gene sequence:

>312_bases
ATGCATAAAGATGTGCTTTTCCGTGGGTGCACACGCCCGGCGATGTTTTTGGGAGTGCCTTACATCCCATTTTTCATCGG
TGCGGGCGGTGGGCTCCTATTGGGGATGTATTTTAATCTTTGGTATCTCTTGACGATTCCTGTCATCATCTTCGTCATGC
AGCAAGTGGCTAAGCGGGACGAGATGATCTTCAGGCTGCTTGGGCTGCGCTGGCTATTTCGTATGCGTGTACGGAATATC
CAGCGCTATTCAGGAATGTGGGTATTCAGTCCCAACGAATATCGAAAGCACCCCGCTGGAAAACGTCAATGA

Upstream 100 bases:

>100_bases
ATTGGTGCGGCCGCTCAGATTGCCAACATGGTAATCGGTGGCGACGGCACTCAGGATTGCAGTACTTCCAGCATGATGCT
GCTTCAGTCCGCCCAATACT

Downstream 100 bases:

>100_bases
GCTAATAGAGCTGCTAACCAACCCCACGCCGGCAAATGCGTGGGGTTGGCACTTTGCAAGATCAAGAATATATCGATGTG
ATGCTTCCCTCTTAACTTGG

Product: VirB3 protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 103; Mature: 103

Protein sequence:

>103_residues
MHKDVLFRGCTRPAMFLGVPYIPFFIGAGGGLLLGMYFNLWYLLTIPVIIFVMQQVAKRDEMIFRLLGLRWLFRMRVRNI
QRYSGMWVFSPNEYRKHPAGKRQ

Sequences:

>Translated_103_residues
MHKDVLFRGCTRPAMFLGVPYIPFFIGAGGGLLLGMYFNLWYLLTIPVIIFVMQQVAKRDEMIFRLLGLRWLFRMRVRNI
QRYSGMWVFSPNEYRKHPAGKRQ
>Mature_103_residues
MHKDVLFRGCTRPAMFLGVPYIPFFIGAGGGLLLGMYFNLWYLLTIPVIIFVMQQVAKRDEMIFRLLGLRWLFRMRVRNI
QRYSGMWVFSPNEYRKHPAGKRQ

Specific function: The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice [H]

COG id: COG3702

COG function: function code U; Type IV secretory pathway, VirB3 components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the virB3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007792 [H]

Pfam domain/function: PF05101 VirB3 [H]

EC number: NA

Molecular weight: Translated: 12245; Mature: 12245

Theoretical pI: Translated: 11.46; Mature: 11.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
6.8 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
6.8 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKDVLFRGCTRPAMFLGVPYIPFFIGAGGGLLLGMYFNLWYLLTIPVIIFVMQQVAKRD
CCCCHHHHCCCCCHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMIFRLLGLRWLFRMRVRNIQRYSGMWVFSPNEYRKHPAGKRQ
HHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHCCCCCCCC
>Mature Secondary Structure
MHKDVLFRGCTRPAMFLGVPYIPFFIGAGGGLLLGMYFNLWYLLTIPVIIFVMQQVAKRD
CCCCHHHHCCCCCHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMIFRLLGLRWLFRMRVRNIQRYSGMWVFSPNEYRKHPAGKRQ
HHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10940027 [H]