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The map label for this gene is yciK [H]

Identifier: 66767941

GI number: 66767941

Start: 1938898

End: 1939638

Strand: Direct

Name: yciK [H]

Synonym: XC_1617

Alternate gene names: 66767941

Gene position: 1938898-1939638 (Clockwise)

Preceding gene: 66767940

Following gene: 66767942

Centisome position: 37.66

GC content: 71.52

Gene sequence:

>741_bases
GTGAGCAGCACGCAGGCAGCCGCTGCAGCGGCGCTGGCCGGGCGGGTCGTGCTGGTCACCGGCGCCGCCGGCGGGTTGGG
CGCTGCGGCCGCGCAGGCCTGCGCACAGGCAGGTGCCACCGTGGTGTTGCTGGGCCGCAAGCTGCGCCCGCTCGAGCGTG
TCTATGACGCGCTGGCCGGGCAGGGCGCAGCACCATTGCTGTACCCGCTGGATCTGGCCGGCGCGACGCCGGACGACTAT
GCCGCGCTCGCACAGCGTCTGCAGTCCGAGTTGGGTGGACTCAGCGGCGTGCTGCATTGCGCCGCCGAGTTCGCCGGGCT
CACGCCGGCTGAACTGGCCGCGCCTGCGGAGTTCGCACGCAGCATCCACGTCAACCTGACCGCACGCGCCTGGCTCACTC
AGGCCTGTCTGCCGCTGCTGCGCCAGCAACAGGATGCGGCGCTGGTGTTCGTCGTGGATGATCCCGCGCGCGTCGGCCAG
GCCTACTGGGGCGCGTACGGCGCTGCCCAGCATGCGCAACGTGGTCTGATTGCCAGCCTGCATCATGAAACGGCCGCCGG
CTCGGTCCGCGTCAGCGGGCTGCAGCCAGGGCCGATGCGCACCGCCTTGCGCGCACGTGCATTTACGCATCAGGAAGACA
GCGACGCGCTGGATCCCGCGCGCTACGCCGCTGCCTGCGTTACCTTGTTGTGCATGGCGGGCGCCTCGCACCGCGGTGCG
ATCTGGAGCCCCCCCGCATGA

Upstream 100 bases:

>100_bases
AGCTCTTCATCCACGGTGAGCTGATCGGTGGCTGCGACATCACCATGGAGCTGTTCGAAGCAGGCGAGCTCAAGCGCATC
GTCAGTGAGGCCTACCAGCC

Downstream 100 bases:

>100_bases
CCATCCTATCGGCAGCGCTGCTGCTGTTCCTGATCCTCGACCCGCTCGGCAACATCCCGGTGTTTCTCAGCGTGCTCAAG
CCGCTGCCGCCGAAGCGCCA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 245

Protein sequence:

>246_residues
MSSTQAAAAAALAGRVVLVTGAAGGLGAAAAQACAQAGATVVLLGRKLRPLERVYDALAGQGAAPLLYPLDLAGATPDDY
AALAQRLQSELGGLSGVLHCAAEFAGLTPAELAAPAEFARSIHVNLTARAWLTQACLPLLRQQQDAALVFVVDDPARVGQ
AYWGAYGAAQHAQRGLIASLHHETAAGSVRVSGLQPGPMRTALRARAFTHQEDSDALDPARYAAACVTLLCMAGASHRGA
IWSPPA

Sequences:

>Translated_246_residues
MSSTQAAAAAALAGRVVLVTGAAGGLGAAAAQACAQAGATVVLLGRKLRPLERVYDALAGQGAAPLLYPLDLAGATPDDY
AALAQRLQSELGGLSGVLHCAAEFAGLTPAELAAPAEFARSIHVNLTARAWLTQACLPLLRQQQDAALVFVVDDPARVGQ
AYWGAYGAAQHAQRGLIASLHHETAAGSVRVSGLQPGPMRTALRARAFTHQEDSDALDPARYAAACVTLLCMAGASHRGA
IWSPPA
>Mature_245_residues
SSTQAAAAAALAGRVVLVTGAAGGLGAAAAQACAQAGATVVLLGRKLRPLERVYDALAGQGAAPLLYPLDLAGATPDDYA
ALAQRLQSELGGLSGVLHCAAEFAGLTPAELAAPAEFARSIHVNLTARAWLTQACLPLLRQQQDAALVFVVDDPARVGQA
YWGAYGAAQHAQRGLIASLHHETAAGSVRVSGLQPGPMRTALRARAFTHQEDSDALDPARYAAACVTLLCMAGASHRGAI
WSPPA

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI5031737, Length=252, Percent_Identity=26.5873015873016, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787526, Length=210, Percent_Identity=37.6190476190476, Blast_Score=113, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21355319, Length=206, Percent_Identity=28.1553398058252, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI21358495, Length=205, Percent_Identity=30.2439024390244, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25089; Mature: 24958

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTQAAAAAALAGRVVLVTGAAGGLGAAAAQACAQAGATVVLLGRKLRPLERVYDALAG
CCCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHC
QGAAPLLYPLDLAGATPDDYAALAQRLQSELGGLSGVLHCAAEFAGLTPAELAAPAEFAR
CCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHCHHHHHH
SIHVNLTARAWLTQACLPLLRQQQDAALVFVVDDPARVGQAYWGAYGAAQHAQRGLIASL
HEEEEEHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHH
HHETAAGSVRVSGLQPGPMRTALRARAFTHQEDSDALDPARYAAACVTLLCMAGASHRGA
HHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
IWSPPA
CCCCCC
>Mature Secondary Structure 
SSTQAAAAAALAGRVVLVTGAAGGLGAAAAQACAQAGATVVLLGRKLRPLERVYDALAG
CCHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHC
QGAAPLLYPLDLAGATPDDYAALAQRLQSELGGLSGVLHCAAEFAGLTPAELAAPAEFAR
CCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHCHHHHHH
SIHVNLTARAWLTQACLPLLRQQQDAALVFVVDDPARVGQAYWGAYGAAQHAQRGLIASL
HEEEEEHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHH
HHETAAGSVRVSGLQPGPMRTALRARAFTHQEDSDALDPARYAAACVTLLCMAGASHRGA
HHHHCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
IWSPPA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]