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The map label for this gene is grxD [H]

Identifier: 66767940

GI number: 66767940

Start: 1938581

End: 1938901

Strand: Direct

Name: grxD [H]

Synonym: XC_1616

Alternate gene names: 66767940

Gene position: 1938581-1938901 (Clockwise)

Preceding gene: 66767938

Following gene: 66767941

Centisome position: 37.65

GC content: 62.31

Gene sequence:

>321_bases
ATGCCGGTGATGGAACGGATCCAGGCCGAAGTCGAGCAGCACCCGATCGTGCTGTTCATGAAAGGCACCCCGCAATTCCC
GATGTGCGGTTTTTCCAGCCGCGCCGTGCAGGCTCTGGTGGCCGCAGGCGCCGACCAGCTGCGCACCGTCAACGTGCTCG
AAGAACCTGAAATCCGCGCCAATCTGCCGCGGTATTCGAACTGGCCGACCTTCCCGCAGCTCTTCATCCACGGTGAGCTG
ATCGGTGGCTGCGACATCACCATGGAGCTGTTCGAAGCAGGCGAGCTCAAGCGCATCGTCAGTGAGGCCTACCAGCCGTG
A

Upstream 100 bases:

>100_bases
AGTCCGGCGAGAGGGCGCGTTGAAGGCTTACAATGCGCGCCTTTGCGGAAGTCTATCCGACCCGGCGGTCGGGCCTGCCG
CTCCCAGTCAGGAGAGTTCA

Downstream 100 bases:

>100_bases
GCAGCACGCAGGCAGCCGCTGCAGCGGCGCTGGCCGGGCGGGTCGTGCTGGTCACCGGCGCCGCCGGCGGGTTGGGCGCT
GCGGCCGCGCAGGCCTGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: Grx4; Monothiol glutaredoxin [H]

Number of amino acids: Translated: 106; Mature: 105

Protein sequence:

>106_residues
MPVMERIQAEVEQHPIVLFMKGTPQFPMCGFSSRAVQALVAAGADQLRTVNVLEEPEIRANLPRYSNWPTFPQLFIHGEL
IGGCDITMELFEAGELKRIVSEAYQP

Sequences:

>Translated_106_residues
MPVMERIQAEVEQHPIVLFMKGTPQFPMCGFSSRAVQALVAAGADQLRTVNVLEEPEIRANLPRYSNWPTFPQLFIHGEL
IGGCDITMELFEAGELKRIVSEAYQP
>Mature_105_residues
PVMERIQAEVEQHPIVLFMKGTPQFPMCGFSSRAVQALVAAGADQLRTVNVLEEPEIRANLPRYSNWPTFPQLFIHGELI
GGCDITMELFEAGELKRIVSEAYQP

Specific function: Monothiol glutaredoxin involved in the biogenesis of iron-sulfur clusters [H]

COG id: COG0278

COG function: function code O; Glutaredoxin-related protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI42516576, Length=92, Percent_Identity=44.5652173913043, Blast_Score=102, Evalue=9e-23,
Organism=Homo sapiens, GI95113651, Length=92, Percent_Identity=45.6521739130435, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1787943, Length=100, Percent_Identity=52, Blast_Score=129, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17556042, Length=101, Percent_Identity=38.6138613861386, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71988153, Length=85, Percent_Identity=44.7058823529412, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71988159, Length=86, Percent_Identity=40.6976744186046, Blast_Score=79, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6325198, Length=103, Percent_Identity=43.6893203883495, Blast_Score=101, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320303, Length=87, Percent_Identity=41.3793103448276, Blast_Score=77, Evalue=7e-16,
Organism=Saccharomyces cerevisiae, GI6321022, Length=89, Percent_Identity=42.6966292134831, Blast_Score=75, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24642023, Length=86, Percent_Identity=43.0232558139535, Blast_Score=89, Evalue=7e-19,
Organism=Drosophila melanogaster, GI19921242, Length=96, Percent_Identity=39.5833333333333, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002109
- InterPro:   IPR014434
- InterPro:   IPR004480
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 11903; Mature: 11772

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVMERIQAEVEQHPIVLFMKGTPQFPMCGFSSRAVQALVAAGADQLRTVNVLEEPEIRA
CCHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCHHHHEEECCCCCCCCCC
NLPRYSNWPTFPQLFIHGELIGGCDITMELFEAGELKRIVSEAYQP
CCCCCCCCCCCCEEEEECCEECCCHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure 
PVMERIQAEVEQHPIVLFMKGTPQFPMCGFSSRAVQALVAAGADQLRTVNVLEEPEIRA
CHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCHHHHEEECCCCCCCCCC
NLPRYSNWPTFPQLFIHGELIGGCDITMELFEAGELKRIVSEAYQP
CCCCCCCCCCCCEEEEECCEECCCHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]