Click here to switch to the map view.

The map label for this gene is cirA [C]

Identifier: 66767785

GI number: 66767785

Start: 1759165

End: 1761231

Strand: Reverse

Name: cirA [C]

Synonym: XC_1459

Alternate gene names: 66767785

Gene position: 1761231-1759165 (Counterclockwise)

Preceding gene: 66767788

Following gene: 66767784

Centisome position: 34.21

GC content: 67.25

Gene sequence:

>2067_bases
ATGTCCCCCAGCCTTTCCTCCCCGCTCCGCCGCTCCACCCTCACGCTGGCCCTGGCCAGTGTGCTGATCCCCGCTCTGGC
CATGGCCGACGACACCCCGGTGCCTGCCGACCCGCAGACCCCGCCCAGTTCCGATACCCGGCATGACGCGACGCCGTCCA
GCGGCCGCCATATCAAGGACCTGGACAAGGTGGTGGTCACCGCCAGCCCGCTGCGCGATGCCGCCGGCGAGCTGAGCCGC
CCGGTCGAGGTGCTGGCAGGCGAGCGCCTGGACGAAGTGCGCGCCTCCAGCCTGGGCGAGACGGTGGCCAGCCTGCCTGG
CGTGCAGAGTTCCAACTTCGGCCCCGGCGTGGGCCGGCCGATCATCCGCGGCCTGGACGGCCCGCGCGTGGCGGTGCTGC
GCGACGGCCTCTCCACGCAGGACGTCTCCACCGTCAGCCAGGACCACTCGCCGGCGATCGAGCCGTTCCTGGCCAACCAG
ATCGAAGTGCTCAAGGGGCCCTCCACCCTGCTGTACGGCTCCGGCGCGATCGGCGGCGTGGTCAACGTGGTCGACGGCCG
CATTGCCGAGACGCCGGTGGATGGCTTCAGCGGGCGCGCCGAAGTGCGCTTCGACGGCGGCGACAAGGATGGCAACACCG
ACATGTTCCGCGTCGATGCCGGTAACGGCAGCGGGCTGTCGATCCACGCCGACGGCGTGTACCGCAACCAGAACGACTAC
GACACCCCGCAAGGGCGCCAGGCCAATTCGTTCCTGGACTCCAAGGTGGGCTCGATCGGTGCCTCGCTGGCGGGCGACTG
GGGCTTTGTCGGCCTGTCTGCCTCGCGGTTCCGCGACAACTATGGCAATCCGGGCGAGCCGGGCGATCTGTCGATCGGCG
AGCGCGGCGTTTCGCTGAAACTGCAGCAGGACCGCTACGACCTCAAGGGCGGGCTGACCGATCCGTGGGGCGATGGCAGC
GCATTGCGTTACAGCTTCGGCCATACCGACTACGCGCACACCGAATTCGAAGGCGCCGAAGTCGGCACCGTGTTCACCAA
GCGCGCCAACGAAGGCCGTGTGGAAGCGTCCTTCACCTTCGGCGGCGGCTGGCAGACTGCGTTCGGCCTGCAGGGCAGCG
ACACCACCTTCCAGGCGGTGGGCGAAGAATCCTTCGTGCCCAAGACCGATACCCGTTCGCTCGGCCTGTTCGGCGTGGCC
CGCAACAGCTGGGACCGCGTGACCGCCGAAGTGGGCGCGCGCGTGGACAAGGTGAAGTACAGCACCGACATCGGCGTGGA
CCGCGACTTCACCCCGACCAGCTTCTCGGCCAGCGCCGGCTTCCGCTTCAACGAGCAGTGGCGCCTCACCGCCAACCTCG
ACCATGCCGAACGCGCGCCGGCCGAGGAAGAACTGTTTGCCAACGGGCCGCACATCGCCACGCTGGCCTTCGAAATCGGC
GACGCCAATCTCAAGACCGAAAAGGCCAACCAGGCCGAGCTGGGTCTGAATTTCCAGAACGACTGGGTGGATGCCAAGAT
CGCGGCGTACTACAACCGCTACAACGACTTCGTCTATATCGTCGATACCGGCGGCCAGTGGTTCAACGAAGAAGACAACG
ACTTCCTGCCGATCCGCCAGTGGACGCAGGCCGACGCCATCTTCCACGGCTTTGAAGGCGAAGCCACCTTCCACCTGGCC
AACAACGACACCGGCGCATGGGACCTGCGCGTGTTCGGCGACACGGTGCAGGCGCGGCTGAAGGATGGCGGCAACCTGCC
GCGCATCGCACCGGGCCGCGTGGGCGCGGAAATGCGCTGGAACGCCGATGCATGGCGCGCGTCGCTGGGCGCGATCCGCA
CCATGAAGCAGGACAAGGTGGCGGTGAACGAAACCGCTACCGACGGCTACACCATGGTGGACGCGCATCTGGCCTACCAC
ATGGATCGCGGCGCCAACGCGTGGGAAGTGTTCCTGGATGGCAACAACCTCACCAACCAGGATGCGCGCGTGCACACCTC
CTTCCTCAAGGACGACGTGATGTTGCCCGGCCGCAACGCCTCCTTCGGCGTGCGCCTGTTCTTCTGA

Upstream 100 bases:

>100_bases
GCACCAGTCCATCACGCAGGTGCGGTGTGTGCCGTCGGCGCAGCAGGCAAGCTGCGCCATTCCATTGATACAAAGTAACA
ACCATAGAGTCCGGTCAGCC

Downstream 100 bases:

>100_bases
CGGCGCTCTCTCTCCCGCCGTCACAAGCGAGGCCGCCTTCGGGCGGCCTCTTCTTTTTTGAAGAGTGCATTCGTGTTGCG
CCATTCCAATTGGTAGCGGT

Product: outer membrane hemin receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 688; Mature: 687

Protein sequence:

>688_residues
MSPSLSSPLRRSTLTLALASVLIPALAMADDTPVPADPQTPPSSDTRHDATPSSGRHIKDLDKVVVTASPLRDAAGELSR
PVEVLAGERLDEVRASSLGETVASLPGVQSSNFGPGVGRPIIRGLDGPRVAVLRDGLSTQDVSTVSQDHSPAIEPFLANQ
IEVLKGPSTLLYGSGAIGGVVNVVDGRIAETPVDGFSGRAEVRFDGGDKDGNTDMFRVDAGNGSGLSIHADGVYRNQNDY
DTPQGRQANSFLDSKVGSIGASLAGDWGFVGLSASRFRDNYGNPGEPGDLSIGERGVSLKLQQDRYDLKGGLTDPWGDGS
ALRYSFGHTDYAHTEFEGAEVGTVFTKRANEGRVEASFTFGGGWQTAFGLQGSDTTFQAVGEESFVPKTDTRSLGLFGVA
RNSWDRVTAEVGARVDKVKYSTDIGVDRDFTPTSFSASAGFRFNEQWRLTANLDHAERAPAEEELFANGPHIATLAFEIG
DANLKTEKANQAELGLNFQNDWVDAKIAAYYNRYNDFVYIVDTGGQWFNEEDNDFLPIRQWTQADAIFHGFEGEATFHLA
NNDTGAWDLRVFGDTVQARLKDGGNLPRIAPGRVGAEMRWNADAWRASLGAIRTMKQDKVAVNETATDGYTMVDAHLAYH
MDRGANAWEVFLDGNNLTNQDARVHTSFLKDDVMLPGRNASFGVRLFF

Sequences:

>Translated_688_residues
MSPSLSSPLRRSTLTLALASVLIPALAMADDTPVPADPQTPPSSDTRHDATPSSGRHIKDLDKVVVTASPLRDAAGELSR
PVEVLAGERLDEVRASSLGETVASLPGVQSSNFGPGVGRPIIRGLDGPRVAVLRDGLSTQDVSTVSQDHSPAIEPFLANQ
IEVLKGPSTLLYGSGAIGGVVNVVDGRIAETPVDGFSGRAEVRFDGGDKDGNTDMFRVDAGNGSGLSIHADGVYRNQNDY
DTPQGRQANSFLDSKVGSIGASLAGDWGFVGLSASRFRDNYGNPGEPGDLSIGERGVSLKLQQDRYDLKGGLTDPWGDGS
ALRYSFGHTDYAHTEFEGAEVGTVFTKRANEGRVEASFTFGGGWQTAFGLQGSDTTFQAVGEESFVPKTDTRSLGLFGVA
RNSWDRVTAEVGARVDKVKYSTDIGVDRDFTPTSFSASAGFRFNEQWRLTANLDHAERAPAEEELFANGPHIATLAFEIG
DANLKTEKANQAELGLNFQNDWVDAKIAAYYNRYNDFVYIVDTGGQWFNEEDNDFLPIRQWTQADAIFHGFEGEATFHLA
NNDTGAWDLRVFGDTVQARLKDGGNLPRIAPGRVGAEMRWNADAWRASLGAIRTMKQDKVAVNETATDGYTMVDAHLAYH
MDRGANAWEVFLDGNNLTNQDARVHTSFLKDDVMLPGRNASFGVRLFF
>Mature_687_residues
SPSLSSPLRRSTLTLALASVLIPALAMADDTPVPADPQTPPSSDTRHDATPSSGRHIKDLDKVVVTASPLRDAAGELSRP
VEVLAGERLDEVRASSLGETVASLPGVQSSNFGPGVGRPIIRGLDGPRVAVLRDGLSTQDVSTVSQDHSPAIEPFLANQI
EVLKGPSTLLYGSGAIGGVVNVVDGRIAETPVDGFSGRAEVRFDGGDKDGNTDMFRVDAGNGSGLSIHADGVYRNQNDYD
TPQGRQANSFLDSKVGSIGASLAGDWGFVGLSASRFRDNYGNPGEPGDLSIGERGVSLKLQQDRYDLKGGLTDPWGDGSA
LRYSFGHTDYAHTEFEGAEVGTVFTKRANEGRVEASFTFGGGWQTAFGLQGSDTTFQAVGEESFVPKTDTRSLGLFGVAR
NSWDRVTAEVGARVDKVKYSTDIGVDRDFTPTSFSASAGFRFNEQWRLTANLDHAERAPAEEELFANGPHIATLAFEIGD
ANLKTEKANQAELGLNFQNDWVDAKIAAYYNRYNDFVYIVDTGGQWFNEEDNDFLPIRQWTQADAIFHGFEGEATFHLAN
NDTGAWDLRVFGDTVQARLKDGGNLPRIAPGRVGAEMRWNADAWRASLGAIRTMKQDKVAVNETATDGYTMVDAHLAYHM
DRGANAWEVFLDGNNLTNQDARVHTSFLKDDVMLPGRNASFGVRLFF

Specific function: Probable receptor, tonB-dependent [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=187, Percent_Identity=26.7379679144385, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1790405, Length=129, Percent_Identity=32.5581395348837, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 74263; Mature: 74132

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPSLSSPLRRSTLTLALASVLIPALAMADDTPVPADPQTPPSSDTRHDATPSSGRHIKD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LDKVVVTASPLRDAAGELSRPVEVLAGERLDEVRASSLGETVASLPGVQSSNFGPGVGRP
HHHEEEECCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
IIRGLDGPRVAVLRDGLSTQDVSTVSQDHSPAIEPFLANQIEVLKGPSTLLYGSGAIGGV
HHHCCCCCEEEEEECCCCCCHHHHHHCCCCCCCCHHHHCCCEEECCCCEEEECCCCCCCE
VNVVDGRIAETPVDGFSGRAEVRFDGGDKDGNTDMFRVDAGNGSGLSIHADGVYRNQNDY
EECCCCCEECCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCEEEEECCEEECCCCC
DTPQGRQANSFLDSKVGSIGASLAGDWGFVGLSASRFRDNYGNPGEPGDLSIGERGVSLK
CCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHCCCCCCCCCCCCCCCCCCCEEE
LQQDRYDLKGGLTDPWGDGSALRYSFGHTDYAHTEFEGAEVGTVFTKRANEGRVEASFTF
ECCCCHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEECEEEEECCCCCEEEEEEEE
GGGWQTAFGLQGSDTTFQAVGEESFVPKTDTRSLGLFGVARNSWDRVTAEVGARVDKVKY
CCCCCEEECCCCCCCHHEECCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCEEEE
STDIGVDRDFTPTSFSASAGFRFNEQWRLTANLDHAERAPAEEELFANGPHIATLAFEIG
ECCCCCCCCCCCCCCCCCCCCEECCEEEEEECCCHHHHCCCHHHHHCCCCEEEEEEEEEC
DANLKTEKANQAELGLNFQNDWVDAKIAAYYNRYNDFVYIVDTGGQWFNEEDNDFLPIRQ
CCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEECCHH
WTQADAIFHGFEGEATFHLANNDTGAWDLRVFGDTVQARLKDGGNLPRIAPGRVGAEMRW
HCCHHHEEECCCCCEEEEEECCCCCEEEEEEECHHHHHHHHCCCCCCCCCCCCCCCEEEE
NADAWRASLGAIRTMKQDKVAVNETATDGYTMVDAHLAYHMDRGANAWEVFLDGNNLTNQ
CHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEHHHHHHHCCCCCEEEEEECCCCCCCC
DARVHTSFLKDDVMLPGRNASFGVRLFF
CHHHHHHHHHCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure 
SPSLSSPLRRSTLTLALASVLIPALAMADDTPVPADPQTPPSSDTRHDATPSSGRHIKD
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
LDKVVVTASPLRDAAGELSRPVEVLAGERLDEVRASSLGETVASLPGVQSSNFGPGVGRP
HHHEEEECCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
IIRGLDGPRVAVLRDGLSTQDVSTVSQDHSPAIEPFLANQIEVLKGPSTLLYGSGAIGGV
HHHCCCCCEEEEEECCCCCCHHHHHHCCCCCCCCHHHHCCCEEECCCCEEEECCCCCCCE
VNVVDGRIAETPVDGFSGRAEVRFDGGDKDGNTDMFRVDAGNGSGLSIHADGVYRNQNDY
EECCCCCEECCCCCCCCCEEEEEECCCCCCCCCCEEEEECCCCCCEEEEECCEEECCCCC
DTPQGRQANSFLDSKVGSIGASLAGDWGFVGLSASRFRDNYGNPGEPGDLSIGERGVSLK
CCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHCCCCCCCCCCCCCCCCCCCEEE
LQQDRYDLKGGLTDPWGDGSALRYSFGHTDYAHTEFEGAEVGTVFTKRANEGRVEASFTF
ECCCCHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEECEEEEECCCCCEEEEEEEE
GGGWQTAFGLQGSDTTFQAVGEESFVPKTDTRSLGLFGVARNSWDRVTAEVGARVDKVKY
CCCCCEEECCCCCCCHHEECCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCEEEE
STDIGVDRDFTPTSFSASAGFRFNEQWRLTANLDHAERAPAEEELFANGPHIATLAFEIG
ECCCCCCCCCCCCCCCCCCCCEECCEEEEEECCCHHHHCCCHHHHHCCCCEEEEEEEEEC
DANLKTEKANQAELGLNFQNDWVDAKIAAYYNRYNDFVYIVDTGGQWFNEEDNDFLPIRQ
CCCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEECCHH
WTQADAIFHGFEGEATFHLANNDTGAWDLRVFGDTVQARLKDGGNLPRIAPGRVGAEMRW
HCCHHHEEECCCCCEEEEEECCCCCEEEEEEECHHHHHHHHCCCCCCCCCCCCCCCEEEE
NADAWRASLGAIRTMKQDKVAVNETATDGYTMVDAHLAYHMDRGANAWEVFLDGNNLTNQ
CHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEHHHHHHHCCCCCEEEEEECCCCCCCC
DARVHTSFLKDDVMLPGRNASFGVRLFF
CHHHHHHHHHCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]