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The map label for this gene is creB [H]

Identifier: 66767745

GI number: 66767745

Start: 1714806

End: 1715501

Strand: Direct

Name: creB [H]

Synonym: XC_1419

Alternate gene names: 66767745

Gene position: 1714806-1715501 (Clockwise)

Preceding gene: 66767734

Following gene: 66767746

Centisome position: 33.31

GC content: 70.55

Gene sequence:

>696_bases
ATGTCCGAGACCCCCGCCCGTGTCCTTGTCGTCGAGGACGAAACCGCCATTGCCGACACCGTGCTGTACGCCCTGCGCAG
CGAGGGCTACGTGCCCGAGCACTGCCTGCTGGGGCGCGAGGCGCTGGAGCGGCTGCGCAACGATCCTGCCGACCTGGTGG
TGCTGGACGTGGGCCTGCCGGATATCAACGGCTTCGAGGTCTGCCGCACGCTGCGCAGTTTCAGCGAGGTGCCGGTGATC
TTCCTGACCGCACGCAACGACGAGATCGACCGCGTGCTGGGCCTGGAACTCGGTGCCGACGACTACATGGCCAAGCCGTT
TTCGCCGCGCGAGCTGGTGGCGCGCGTGCGCGCACGGCTGCGCCGGCGCAGCGTGGCCGTGGCCCAGGCCGAACCGGGCT
GGCAGCCGCACGGCGCGTTCGCGATTGATCGCGACGGCAGTCGCATCCGCTACGGCGAGACGCTGTTGCCGCTGACGCGC
TACGAATACGCGCTGCTGGCCGCGCTGCTGCAACGGCCCGGCGCCATCCTCAGCCGCACCCAGCTGATGGACCGCGGCTG
GGATGCCAGCGCCGACAGCGCCGACCGCACCGTGGATACCCATATCAAGACGCTGCGCGCCAAGCTGCGCCAGGCCGGCG
TGCCGGCCGACCCGATCCGCACCCACCGTGGCCTTGGCTACGCGCTGGAGGTCTGA

Upstream 100 bases:

>100_bases
AGGTGCAGCCAGTGTTGTGTGGTCGATGATGGCCCGCAGCGGCCGTGCACGGTGGCCGGCGTGCTATTGGCCGCGCCGGC
ATGCGGCTATGCTGCGCGCC

Downstream 100 bases:

>100_bases
GGATGGGTGCCGTATTTCAGAAGCCGGCGGTCGGGGTGGTCGAGCGTGCTGGTTTGCTTGGTCGGCGTGGGCTGACAGAA
GTGAACGGCCTGGCGGTCGG

Product: DNA-binding response regulator CreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MSETPARVLVVEDETAIADTVLYALRSEGYVPEHCLLGREALERLRNDPADLVVLDVGLPDINGFEVCRTLRSFSEVPVI
FLTARNDEIDRVLGLELGADDYMAKPFSPRELVARVRARLRRRSVAVAQAEPGWQPHGAFAIDRDGSRIRYGETLLPLTR
YEYALLAALLQRPGAILSRTQLMDRGWDASADSADRTVDTHIKTLRAKLRQAGVPADPIRTHRGLGYALEV

Sequences:

>Translated_231_residues
MSETPARVLVVEDETAIADTVLYALRSEGYVPEHCLLGREALERLRNDPADLVVLDVGLPDINGFEVCRTLRSFSEVPVI
FLTARNDEIDRVLGLELGADDYMAKPFSPRELVARVRARLRRRSVAVAQAEPGWQPHGAFAIDRDGSRIRYGETLLPLTR
YEYALLAALLQRPGAILSRTQLMDRGWDASADSADRTVDTHIKTLRAKLRQAGVPADPIRTHRGLGYALEV
>Mature_230_residues
SETPARVLVVEDETAIADTVLYALRSEGYVPEHCLLGREALERLRNDPADLVVLDVGLPDINGFEVCRTLRSFSEVPVIF
LTARNDEIDRVLGLELGADDYMAKPFSPRELVARVRARLRRRSVAVAQAEPGWQPHGAFAIDRDGSRIRYGETLLPLTRY
EYALLAALLQRPGAILSRTQLMDRGWDASADSADRTVDTHIKTLRAKLRQAGVPADPIRTHRGLGYALEV

Specific function: Member of the two-component regulatory system CreC/CreB involved in catabolic regulation [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=52.0179372197309, Blast_Score=218, Evalue=2e-58,
Organism=Escherichia coli, GI1788394, Length=234, Percent_Identity=39.3162393162393, Blast_Score=163, Evalue=9e-42,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=38.3928571428571, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=36.7713004484305, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=35.3982300884956, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787229, Length=237, Percent_Identity=37.9746835443038, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=40.7079646017699, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=36.7965367965368, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=35.7142857142857, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1790863, Length=238, Percent_Identity=33.6134453781513, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=36.283185840708, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI2367329, Length=182, Percent_Identity=40.6593406593407, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=31.858407079646, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI145693140, Length=198, Percent_Identity=28.7878787878788, Blast_Score=81, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25714; Mature: 25582

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETPARVLVVEDETAIADTVLYALRSEGYVPEHCLLGREALERLRNDPADLVVLDVGLP
CCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCC
DINGFEVCRTLRSFSEVPVIFLTARNDEIDRVLGLELGADDYMAKPFSPRELVARVRARL
CCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCEECCCHHHCCCCCHHHHHHHHHHHH
RRRSVAVAQAEPGWQPHGAFAIDRDGSRIRYGETLLPLTRYEYALLAALLQRPGAILSRT
HHHHHHEEECCCCCCCCCCEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHH
QLMDRGWDASADSADRTVDTHIKTLRAKLRQAGVPADPIRTHRGLGYALEV
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEECC
>Mature Secondary Structure 
SETPARVLVVEDETAIADTVLYALRSEGYVPEHCLLGREALERLRNDPADLVVLDVGLP
CCCCCEEEEEECCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCC
DINGFEVCRTLRSFSEVPVIFLTARNDEIDRVLGLELGADDYMAKPFSPRELVARVRARL
CCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHCEECCCHHHCCCCCHHHHHHHHHHHH
RRRSVAVAQAEPGWQPHGAFAIDRDGSRIRYGETLLPLTRYEYALLAALLQRPGAILSRT
HHHHHHEEECCCCCCCCCCEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHH
QLMDRGWDASADSADRTVDTHIKTLRAKLRQAGVPADPIRTHRGLGYALEV
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3531171; 7610040; 9278503 [H]