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The map label for this gene is lytH [H]

Identifier: 66767681

GI number: 66767681

Start: 1638890

End: 1639480

Strand: Reverse

Name: lytH [H]

Synonym: XC_1354

Alternate gene names: 66767681

Gene position: 1639480-1638890 (Counterclockwise)

Preceding gene: 66767682

Following gene: 66767680

Centisome position: 31.84

GC content: 68.02

Gene sequence:

>591_bases
GTGCCCGTGACCGCGCCATCGCCCACCCGCAGCCCAGCCAGACGCGTGCGCCACCTGCTGGTATCGATCGTGATGCTGTG
CGCGCTGGGTGTTGCCGCGCGCTGGGCCTGGCTGTCACCGATGGCCGAACGCCTGCGCACCAGCTGGGAGTTATCGCAAA
TGCCGGCACCCACGCAGTTGCACATCCCGGTAGACGGTGTGCGTGGTCGCCAGATTGCCGACACCTTCGGCGCCCCACGC
GGACGCGACCGCAGCCATGCCGGTGTCGATATCTTCGCGCCGCGCGGCACAGCGGTAGTGGCTGCCACCCGTGGCGTAGT
CAGTTCCATTCGCGACACAGGGCTGGGTGGCAAACAGGTGTGGGTGCTTGGGCCGGCGATGGAACGGCACTACTACGCGC
ACCTGGACGACTGGGCACCCGGACTGGCAGTCGGCGATGTGGTCGAGCCCGGCACTGCACTGGGCATGGTCGGCACCACC
GGCAACGCGCGTGGTACGCCGCCGCATCTTCATTACGGGATCTATGGGCGCAACGGTGCGTACGATCCGTTGCCACTGCT
CCGGCAACCCGCGCCACAGCAGGCACCCTGA

Upstream 100 bases:

>100_bases
TTTTTTTGCGCGTTTGCCACGTCTTCTCCGCCTCCTGACAGGCACACCACATCGCACTCATCGCCGCTGCCCTACCCTGG
CGGTGAGTTCGCAACCAAGA

Downstream 100 bases:

>100_bases
GCGCGCTGGAACACTGCGTCATGGCCCGGCCTATCGAGACCCTGCGCATGCGCGCCTATGGTGGAGCCAGCCCCACAGTG
ACGCGACCTTCCATGTCCCG

Product: peptidase

Products: NA

Alternate protein names: Peptidoglycan hydrolase; Sporulation-specific endopeptidase [H]

Number of amino acids: Translated: 196; Mature: 195

Protein sequence:

>196_residues
MPVTAPSPTRSPARRVRHLLVSIVMLCALGVAARWAWLSPMAERLRTSWELSQMPAPTQLHIPVDGVRGRQIADTFGAPR
GRDRSHAGVDIFAPRGTAVVAATRGVVSSIRDTGLGGKQVWVLGPAMERHYYAHLDDWAPGLAVGDVVEPGTALGMVGTT
GNARGTPPHLHYGIYGRNGAYDPLPLLRQPAPQQAP

Sequences:

>Translated_196_residues
MPVTAPSPTRSPARRVRHLLVSIVMLCALGVAARWAWLSPMAERLRTSWELSQMPAPTQLHIPVDGVRGRQIADTFGAPR
GRDRSHAGVDIFAPRGTAVVAATRGVVSSIRDTGLGGKQVWVLGPAMERHYYAHLDDWAPGLAVGDVVEPGTALGMVGTT
GNARGTPPHLHYGIYGRNGAYDPLPLLRQPAPQQAP
>Mature_195_residues
PVTAPSPTRSPARRVRHLLVSIVMLCALGVAARWAWLSPMAERLRTSWELSQMPAPTQLHIPVDGVRGRQIADTFGAPRG
RDRSHAGVDIFAPRGTAVVAATRGVVSSIRDTGLGGKQVWVLGPAMERHYYAHLDDWAPGLAVGDVVEPGTALGMVGTTG
NARGTPPHLHYGIYGRNGAYDPLPLLRQPAPQQAP

Specific function: L-Ala--D-Glu endopeptidase involved in production of single L-alanine side chains from tetrapeptides in the spore cortex peptidoglycan. Therefore, is required for the endospore cortex maturation [H]

COG id: COG0739

COG function: function code M; Membrane proteins related to metalloendopeptidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M23B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR016047 [H]

Pfam domain/function: PF01551 Peptidase_M23 [H]

EC number: NA

Molecular weight: Translated: 20970; Mature: 20839

Theoretical pI: Translated: 10.79; Mature: 10.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVTAPSPTRSPARRVRHLLVSIVMLCALGVAARWAWLSPMAERLRTSWELSQMPAPTQL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
HIPVDGVRGRQIADTFGAPRGRDRSHAGVDIFAPRGTAVVAATRGVVSSIRDTGLGGKQV
EECCCCCCCCCHHHHHCCCCCCCCCCCCEEEECCCCCEEEEHHHHHHHHHHHCCCCCCEE
WVLGPAMERHYYAHLDDWAPGLAVGDVVEPGTALGMVGTTGNARGTPPHLHYGIYGRNGA
EEECCHHHHHEEEECCCCCCCCEECCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCC
YDPLPLLRQPAPQQAP
CCCCHHHCCCCCCCCC
>Mature Secondary Structure 
PVTAPSPTRSPARRVRHLLVSIVMLCALGVAARWAWLSPMAERLRTSWELSQMPAPTQL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
HIPVDGVRGRQIADTFGAPRGRDRSHAGVDIFAPRGTAVVAATRGVVSSIRDTGLGGKQV
EECCCCCCCCCHHHHHCCCCCCCCCCCCEEEECCCCCEEEEHHHHHHHHHHHCCCCCCEE
WVLGPAMERHYYAHLDDWAPGLAVGDVVEPGTALGMVGTTGNARGTPPHLHYGIYGRNGA
EEECCHHHHHEEEECCCCCCCCEECCCCCCCCEEEEEECCCCCCCCCCEEEEEEECCCCC
YDPLPLLRQPAPQQAP
CCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12813075 [H]