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The map label for this gene is aroK [H]

Identifier: 66767596

GI number: 66767596

Start: 1557493

End: 1558053

Strand: Reverse

Name: aroK [H]

Synonym: XC_1269

Alternate gene names: 66767596

Gene position: 1558053-1557493 (Counterclockwise)

Preceding gene: 66767606

Following gene: 162017106

Centisome position: 30.26

GC content: 68.81

Gene sequence:

>561_bases
ATGTTACGATCCGGGCGCATGAACCCCGCTCCCAATCTCGTGATGATCGGCCCGATGGGCGCCGGTAAAAGCTGCATCGG
CCGCCGCCTGGCCGAGCGCTTCGGGCTGGATTTCGTGGATGTGGACCAGGCCATCGTCGAGCAGGTCGGCAGCAGCATCC
CCGCGATCTTCGAACAGCACGGCGAAGCGCGCTTTCGCCAGCACGAAGCCGAGGCCCTGCACGGCCTGCTCGCGCAGAGC
AACAAACTGGTCTCCACCGGCGGCGGCGCGATCCTGGATGCGGGCAATCGCCAGCGCATCCGCGAGCGCGGCTTCGTGGT
GTACCTGCATGTGAGCGTGCCGGCCCAGCTCACCCGGCTGGCGCGCGACCGCAATCGCCCGCTGCTGCAGCGCCCGGACC
GCGAACAGGTGCTGCACGGCATGGCCGCGCTGCGCACCCCGCTGTACCAGGAAGTGGCCGACCTCACCCTGGAAACCGAT
CACCTTTCCCCCGCCGAGGCCACCGCGCAGCTGGTGCTGCGCCTGGCCGCGCAATGGCGCATGTCGAGTACCCCTGCATG
A

Upstream 100 bases:

>100_bases
TGGCGGCTGCGGCCAAGGCCGGCAGCGCAGGATCTGCAGCGACAGCCCACGCCGCCGGGAGGATCACGCATGGCGCACGC
GGCCCTGGGCCGCAATGCCA

Downstream 100 bases:

>100_bases
CTCTTCCCCCCTCCTTGCGCAGCGTCGAAGTCGACGGCGCGCAGCCGTACACCATCTCCATTGCGCCGGGCCTGCTGGCC
GACGGCGCGCGCCTGGCCCG

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MLRSGRMNPAPNLVMIGPMGAGKSCIGRRLAERFGLDFVDVDQAIVEQVGSSIPAIFEQHGEARFRQHEAEALHGLLAQS
NKLVSTGGGAILDAGNRQRIRERGFVVYLHVSVPAQLTRLARDRNRPLLQRPDREQVLHGMAALRTPLYQEVADLTLETD
HLSPAEATAQLVLRLAAQWRMSSTPA

Sequences:

>Translated_186_residues
MLRSGRMNPAPNLVMIGPMGAGKSCIGRRLAERFGLDFVDVDQAIVEQVGSSIPAIFEQHGEARFRQHEAEALHGLLAQS
NKLVSTGGGAILDAGNRQRIRERGFVVYLHVSVPAQLTRLARDRNRPLLQRPDREQVLHGMAALRTPLYQEVADLTLETD
HLSPAEATAQLVLRLAAQWRMSSTPA
>Mature_186_residues
MLRSGRMNPAPNLVMIGPMGAGKSCIGRRLAERFGLDFVDVDQAIVEQVGSSIPAIFEQHGEARFRQHEAEALHGLLAQS
NKLVSTGGGAILDAGNRQRIRERGFVVYLHVSVPAQLTRLARDRNRPLLQRPDREQVLHGMAALRTPLYQEVADLTLETD
HLSPAEATAQLVLRLAAQWRMSSTPA

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=168, Percent_Identity=39.8809523809524, Blast_Score=134, Evalue=3e-33,
Organism=Escherichia coli, GI1786587, Length=163, Percent_Identity=33.7423312883436, Blast_Score=81, Evalue=5e-17,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 20462; Mature: 20462

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRSGRMNPAPNLVMIGPMGAGKSCIGRRLAERFGLDFVDVDQAIVEQVGSSIPAIFEQH
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHH
GEARFRQHEAEALHGLLAQSNKLVSTGGGAILDAGNRQRIRERGFVVYLHVSVPAQLTRL
HHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEECCCHHHHHHCCEEEEEEECCHHHHHHH
ARDRNRPLLQRPDREQVLHGMAALRTPLYQEVADLTLETDHLSPAEATAQLVLRLAAQWR
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
MSSTPA
CCCCCC
>Mature Secondary Structure
MLRSGRMNPAPNLVMIGPMGAGKSCIGRRLAERFGLDFVDVDQAIVEQVGSSIPAIFEQH
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHH
GEARFRQHEAEALHGLLAQSNKLVSTGGGAILDAGNRQRIRERGFVVYLHVSVPAQLTRL
HHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEECCCHHHHHHCCEEEEEEECCHHHHHHH
ARDRNRPLLQRPDREQVLHGMAALRTPLYQEVADLTLETDHLSPAEATAQLVLRLAAQWR
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
MSSTPA
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA