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The map label for this gene is aroB [H]

Identifier: 162017106

GI number: 162017106

Start: 1556384

End: 1557496

Strand: Reverse

Name: aroB [H]

Synonym: XC_1268

Alternate gene names: 162017106

Gene position: 1557496-1556384 (Counterclockwise)

Preceding gene: 66767596

Following gene: 66767593

Centisome position: 30.25

GC content: 69.63

Gene sequence:

>1113_bases
ATGACTCTTCCCCCCTCCTTGCGCAGCGTCGAAGTCGACGGCGCGCAGCCGTACACCATCTCCATTGCGCCGGGCCTGCT
GGCCGACGGCGCGCGCCTGGCCCGCCACGTACGCGGCCGCCACGTGCTGCTGCTCAGCGACACCCAGGTGGCGCCGCACT
ATGCCGCCGGCGTGCGCGCTGCACTGTTGCAGGCGCGGCCGGACCTGCAGCTTGGCGAACTGGTCATCGCCGCCGGCGAA
GCCTCCAAAACCCTGGACAACTTCTCCCTGGCGATCACCGCACTGGCCGAACTGGGCGCCACCCGCGATGCCTGCGTGTT
CGCGCTCGGCGGTGGCGTGGTCGGCGATCTGGCCGGCTTTGCTGCCGCCTGCTGGATGCGCGGGGTGGATTGCGTGCAAC
TGCCCACCAGCCTGCTGGCGATGGTGGATTCCTCGGTCGGTGGCAAGACCGCGGTGGACATCCCGCAGGGCAAGAACCTG
GTGGGGGCATTCCACCCGCCACGCGCGGTGATTGCCGATACCGACACCTTGCGCACCCTGCCCACGCGCGAGCTGCGCGC
TGGCCTGGCGGAGGTAATCAAGTACGGCGCCATCGGCGACCCGTTGTTCTTCCAGTGGCTGCATGCCGAACGCCGCGCGC
TGCTGGACGGCGACCCGGCCGCGCTGGCGCAGGCGATTGCACGCAGTTGCGAGCACAAGGCCGACATCGTGGCGCGCGAC
CCGCTGGAAAAAGGCGAGCGCGCCCTGCTCAACCTGGGCCACACCTTCGGCCACGCCATCGAGACAGAACAGGGCTACGG
CGCGCCGGGTAACGACAACCTCAACCATGGCGAAGCGGTGGCAGTGGGCATGGTGCTGGCAGCGCGGCTCTCGGCCGCAC
TGGGCATGGCCGACGCCCAGGACACCGAGGCACTGCGCACCCTGCTGCATGAATTCGGCCTGCCCACCCAGATCCCGACC
GGCCTGGCACCGGAAGCCCTGCTCGGCCGCATGCGGCTGGACAAGAAAAACATCGCCGGCCGCCTGCGCCTGGTGCTGTG
GCGCGGGATCGGCAAGGCCGAAGTCGTCCCCGACGTGGACGAAGCTGCGGTGCTGGAGATTCTGGCCGACTGA

Upstream 100 bases:

>100_bases
CCGACCTCACCCTGGAAACCGATCACCTTTCCCCCGCCGAGGCCACCGCGCAGCTGGTGCTGCGCCTGGCCGCGCAATGG
CGCATGTCGAGTACCCCTGC

Downstream 100 bases:

>100_bases
GGTTTGTGCTCGCCGGCTGACGTTTGCGCTAGCCGACTGAGGTTTGGCGCTGGTCAGGTGATCTGGCTCATGCGCGGCCG
CGAGGCAAAATAGGCGTCCG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MTLPPSLRSVEVDGAQPYTISIAPGLLADGARLARHVRGRHVLLLSDTQVAPHYAAGVRAALLQARPDLQLGELVIAAGE
ASKTLDNFSLAITALAELGATRDACVFALGGGVVGDLAGFAAACWMRGVDCVQLPTSLLAMVDSSVGGKTAVDIPQGKNL
VGAFHPPRAVIADTDTLRTLPTRELRAGLAEVIKYGAIGDPLFFQWLHAERRALLDGDPAALAQAIARSCEHKADIVARD
PLEKGERALLNLGHTFGHAIETEQGYGAPGNDNLNHGEAVAVGMVLAARLSAALGMADAQDTEALRTLLHEFGLPTQIPT
GLAPEALLGRMRLDKKNIAGRLRLVLWRGIGKAEVVPDVDEAAVLEILAD

Sequences:

>Translated_370_residues
MTLPPSLRSVEVDGAQPYTISIAPGLLADGARLARHVRGRHVLLLSDTQVAPHYAAGVRAALLQARPDLQLGELVIAAGE
ASKTLDNFSLAITALAELGATRDACVFALGGGVVGDLAGFAAACWMRGVDCVQLPTSLLAMVDSSVGGKTAVDIPQGKNL
VGAFHPPRAVIADTDTLRTLPTRELRAGLAEVIKYGAIGDPLFFQWLHAERRALLDGDPAALAQAIARSCEHKADIVARD
PLEKGERALLNLGHTFGHAIETEQGYGAPGNDNLNHGEAVAVGMVLAARLSAALGMADAQDTEALRTLLHEFGLPTQIPT
GLAPEALLGRMRLDKKNIAGRLRLVLWRGIGKAEVVPDVDEAAVLEILAD
>Mature_369_residues
TLPPSLRSVEVDGAQPYTISIAPGLLADGARLARHVRGRHVLLLSDTQVAPHYAAGVRAALLQARPDLQLGELVIAAGEA
SKTLDNFSLAITALAELGATRDACVFALGGGVVGDLAGFAAACWMRGVDCVQLPTSLLAMVDSSVGGKTAVDIPQGKNLV
GAFHPPRAVIADTDTLRTLPTRELRAGLAEVIKYGAIGDPLFFQWLHAERRALLDGDPAALAQAIARSCEHKADIVARDP
LEKGERALLNLGHTFGHAIETEQGYGAPGNDNLNHGEAVAVGMVLAARLSAALGMADAQDTEALRTLLHEFGLPTQIPTG
LAPEALLGRMRLDKKNIAGRLRLVLWRGIGKAEVVPDVDEAAVLEILAD

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=363, Percent_Identity=49.0358126721763, Blast_Score=287, Evalue=6e-79,
Organism=Saccharomyces cerevisiae, GI6320332, Length=378, Percent_Identity=33.8624338624339, Blast_Score=174, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 38830; Mature: 38699

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLPPSLRSVEVDGAQPYTISIAPGLLADGARLARHVRGRHVLLLSDTQVAPHYAAGVRA
CCCCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHH
ALLQARPDLQLGELVIAAGEASKTLDNFSLAITALAELGATRDACVFALGGGVVGDLAGF
HHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHH
AAACWMRGVDCVQLPTSLLAMVDSSVGGKTAVDIPQGKNLVGAFHPPRAVIADTDTLRTL
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEECCCCCCEEEECCHHHHCC
PTRELRAGLAEVIKYGAIGDPLFFQWLHAERRALLDGDPAALAQAIARSCEHKADIVARD
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEECC
PLEKGERALLNLGHTFGHAIETEQGYGAPGNDNLNHGEAVAVGMVLAARLSAALGMADAQ
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCH
DTEALRTLLHEFGLPTQIPTGLAPEALLGRMRLDKKNIAGRLRLVLWRGIGKAEVVPDVD
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHEEEEECCCCCCCCCCCCH
EAAVLEILAD
HHHHHHHHCC
>Mature Secondary Structure 
TLPPSLRSVEVDGAQPYTISIAPGLLADGARLARHVRGRHVLLLSDTQVAPHYAAGVRA
CCCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHH
ALLQARPDLQLGELVIAAGEASKTLDNFSLAITALAELGATRDACVFALGGGVVGDLAGF
HHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHH
AAACWMRGVDCVQLPTSLLAMVDSSVGGKTAVDIPQGKNLVGAFHPPRAVIADTDTLRTL
HHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCEECCCCCCEEEECCHHHHCC
PTRELRAGLAEVIKYGAIGDPLFFQWLHAERRALLDGDPAALAQAIARSCEHKADIVARD
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCEEECC
PLEKGERALLNLGHTFGHAIETEQGYGAPGNDNLNHGEAVAVGMVLAARLSAALGMADAQ
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCH
DTEALRTLLHEFGLPTQIPTGLAPEALLGRMRLDKKNIAGRLRLVLWRGIGKAEVVPDVD
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHEEEEECCCCCCCCCCCCH
EAAVLEILAD
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]