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The map label for this gene is bga [H]

Identifier: 66767541

GI number: 66767541

Start: 1476358

End: 1478199

Strand: Reverse

Name: bga [H]

Synonym: XC_1214

Alternate gene names: 66767541

Gene position: 1478199-1476358 (Counterclockwise)

Preceding gene: 66767542

Following gene: 66767535

Centisome position: 28.71

GC content: 64.5

Gene sequence:

>1842_bases
ATGTTGCGTACCACGCTTGCCCCGCTTGTCCTGGCCCTGTCCATCGCACTGCCCATCACCGCCACGGCCGCCAGCGATGA
CCAGTGGCCCACCTTCGCCACCCAGGGCACGCAGTTCGTGCGCGACGGCAAGCCGTACCAAGTGCTTTCCGGTGCCATCC
ATTTCCAGCGCATTCCGCGTACCTACTGGAAAGACCGCCTGCAAAAAGCGCGTGCGCTGGGCTTGAACACGGTGGAAACC
TACGTGTTCTGGAACCTGGTCGAACCGCAGCAGGGGCAATTCGATTTCAACGCCAATAACGACGTGGCCGCGTTCGTGCG
CGAGGCCGCCGCGCAAGGTCTCAACGTGATCCTGCGGCCGGGCCCGTACGCCTGTGCGGAATGGGAAGCCGGTGGGTATC
CGGCCTGGCTCTTCGGCAAGGACAACATCCGCATACGCAGCCGCGACCCGCGCTTTCTCGCCGCCAGCCAGTCCTACCTG
GATGCAGTGGCGCAGCAGGTGCGCCCACTGCTCAACCACAACGGCGGCCCGATCATCGCCGTGCAGGTAGAGAACGAATA
CGGCTCCTACGACGACGACCATGCCTACATCGCCGACAACCGCGCCATGTTCGTCAAGGCCGGCTTCGACAAGGCGCTGC
TGTTTACCTCCGACGGCGCAGACATGCTCGCCAACGGCACCCTGCCGGGCACGTTGGCCGTGGTCAATTTCGCCCCGGGC
GAGGCCAAGAGTGCGTTCGACAAACTGATCAAGTTTCAGCCAGACCAACCGCGCATGGTCGGCGAATACTGGGCCGGCTG
GTTCGACCATTGGGGCACGCCGCACGCCAGCACCAACGCCAAGCAGCAAACCGAAGAACTGGAATGGATCCTGCGCCAGG
GCCATTCCGCCAACCTCTACATGTTCATCGGCGGCACCAGTTTCGGCTTCATGAATGGTGCCAATTTTCAGGGCAATCCC
AGCGACCATTACGCACCGCAGACCACCAGCTACGACTACGACGCCATCCTGGACGAAGCCGGCCGCCCCACGCCCAAGTT
CGCGCTGATGCGCGATGTCATCACGCGCGTCACCGGCGTGCAGCCGCCGGCCTTGCCGGCACCGATCGCCATGGCCGCGC
TGAAAGACGCACCGCTGCGCGAGTCGGCCTCGCTGTGGGACAACCTGCCCGCGCCCATCGCCATCGACACGCCGCAGCCG
ATGGAACATTTCGGCCAGGACTATGGCTACATCCTGTATCGCACCACCGTCACCGGCCCGCGCAAGGAGTCGCTGTATCT
GGGCGAGGTACGCGACGTAGCACGCGTCTATGTGGATCAGAAGCCTGTTGGTAGCGTCGAACGCCGGCTGCAACAGGTCG
CCACCGAGGTGGACATTCCGGCTGGCCAACACACCCTGGATGTTCTGGTCGAAAACAGCGGCCGCATCAACTACGGCCCG
CGCATGGCCGACGGCCGCGCCGGCCTGGTCGACCCGGTACTGCTGGACAACCAGCAACTCACCAACTGGCAGGCCTTCCC
GCTCCCCATGCGCTCGCCGGACAGCATCCGCGGCTGGACGCGTAACACAGTGGAAGGCCCCGCCTTTCATCGCGGCAACC
TGCGCATCGGCACGCCCGCCGACACCTACCTGGACATGCGCGCATTCGGCAAAGGCATCGCCTGGGCCAACGGCGTCAAC
CTCGGCAGGCACTGGAACATCGGCCCGCAACGTGCGCTGTACTTCCCGGCACCGTTCCAGCGCAAGGGCGACAACACCGT
GGTGGTGTTCGATCTGGACAGCACCGCCAAGCCCAGCGTGCGTGGTTTGCAGCAGCAGGTGTGGATCACGCCGAAGGAGT
AA

Upstream 100 bases:

>100_bases
TGCGCGCACAGCACCGCACTGCAGCCTGGCCCGTCATCCGTTCGTATCACTCGCCCCACGTCATTCGTCATTCGTCATTC
GTCATCGCCGAGAATTGCCC

Downstream 100 bases:

>100_bases
GCGCGGCCAAGAAACCACCGCGCTCATCATCAGACGGGCGCAGCGTTCGCTTCGATCGGTTAAGAGCCGCCAACAAAACT
ACTGCGTGGCCACCAGACGG

Product: beta-galactosidase

Products: NA

Alternate protein names: Lactase [H]

Number of amino acids: Translated: 613; Mature: 613

Protein sequence:

>613_residues
MLRTTLAPLVLALSIALPITATAASDDQWPTFATQGTQFVRDGKPYQVLSGAIHFQRIPRTYWKDRLQKARALGLNTVET
YVFWNLVEPQQGQFDFNANNDVAAFVREAAAQGLNVILRPGPYACAEWEAGGYPAWLFGKDNIRIRSRDPRFLAASQSYL
DAVAQQVRPLLNHNGGPIIAVQVENEYGSYDDDHAYIADNRAMFVKAGFDKALLFTSDGADMLANGTLPGTLAVVNFAPG
EAKSAFDKLIKFQPDQPRMVGEYWAGWFDHWGTPHASTNAKQQTEELEWILRQGHSANLYMFIGGTSFGFMNGANFQGNP
SDHYAPQTTSYDYDAILDEAGRPTPKFALMRDVITRVTGVQPPALPAPIAMAALKDAPLRESASLWDNLPAPIAIDTPQP
MEHFGQDYGYILYRTTVTGPRKESLYLGEVRDVARVYVDQKPVGSVERRLQQVATEVDIPAGQHTLDVLVENSGRINYGP
RMADGRAGLVDPVLLDNQQLTNWQAFPLPMRSPDSIRGWTRNTVEGPAFHRGNLRIGTPADTYLDMRAFGKGIAWANGVN
LGRHWNIGPQRALYFPAPFQRKGDNTVVVFDLDSTAKPSVRGLQQQVWITPKE

Sequences:

>Translated_613_residues
MLRTTLAPLVLALSIALPITATAASDDQWPTFATQGTQFVRDGKPYQVLSGAIHFQRIPRTYWKDRLQKARALGLNTVET
YVFWNLVEPQQGQFDFNANNDVAAFVREAAAQGLNVILRPGPYACAEWEAGGYPAWLFGKDNIRIRSRDPRFLAASQSYL
DAVAQQVRPLLNHNGGPIIAVQVENEYGSYDDDHAYIADNRAMFVKAGFDKALLFTSDGADMLANGTLPGTLAVVNFAPG
EAKSAFDKLIKFQPDQPRMVGEYWAGWFDHWGTPHASTNAKQQTEELEWILRQGHSANLYMFIGGTSFGFMNGANFQGNP
SDHYAPQTTSYDYDAILDEAGRPTPKFALMRDVITRVTGVQPPALPAPIAMAALKDAPLRESASLWDNLPAPIAIDTPQP
MEHFGQDYGYILYRTTVTGPRKESLYLGEVRDVARVYVDQKPVGSVERRLQQVATEVDIPAGQHTLDVLVENSGRINYGP
RMADGRAGLVDPVLLDNQQLTNWQAFPLPMRSPDSIRGWTRNTVEGPAFHRGNLRIGTPADTYLDMRAFGKGIAWANGVN
LGRHWNIGPQRALYFPAPFQRKGDNTVVVFDLDSTAKPSVRGLQQQVWITPKE
>Mature_613_residues
MLRTTLAPLVLALSIALPITATAASDDQWPTFATQGTQFVRDGKPYQVLSGAIHFQRIPRTYWKDRLQKARALGLNTVET
YVFWNLVEPQQGQFDFNANNDVAAFVREAAAQGLNVILRPGPYACAEWEAGGYPAWLFGKDNIRIRSRDPRFLAASQSYL
DAVAQQVRPLLNHNGGPIIAVQVENEYGSYDDDHAYIADNRAMFVKAGFDKALLFTSDGADMLANGTLPGTLAVVNFAPG
EAKSAFDKLIKFQPDQPRMVGEYWAGWFDHWGTPHASTNAKQQTEELEWILRQGHSANLYMFIGGTSFGFMNGANFQGNP
SDHYAPQTTSYDYDAILDEAGRPTPKFALMRDVITRVTGVQPPALPAPIAMAALKDAPLRESASLWDNLPAPIAIDTPQP
MEHFGQDYGYILYRTTVTGPRKESLYLGEVRDVARVYVDQKPVGSVERRLQQVATEVDIPAGQHTLDVLVENSGRINYGP
RMADGRAGLVDPVLLDNQQLTNWQAFPLPMRSPDSIRGWTRNTVEGPAFHRGNLRIGTPADTYLDMRAFGKGIAWANGVN
LGRHWNIGPQRALYFPAPFQRKGDNTVVVFDLDSTAKPSVRGLQQQVWITPKE

Specific function: Preferentially hydrolyzes beta(1->3) galactosyl linkages over beta(1->4) linkages [H]

COG id: COG1874

COG function: function code G; Beta-galactosidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 35 family [H]

Homologues:

Organism=Homo sapiens, GI31543093, Length=585, Percent_Identity=40.8547008547009, Blast_Score=413, Evalue=1e-115,
Organism=Homo sapiens, GI119372312, Length=595, Percent_Identity=40.672268907563, Blast_Score=387, Evalue=1e-107,
Organism=Homo sapiens, GI119372308, Length=595, Percent_Identity=40.672268907563, Blast_Score=387, Evalue=1e-107,
Organism=Homo sapiens, GI40255043, Length=593, Percent_Identity=39.6290050590219, Blast_Score=380, Evalue=1e-105,
Organism=Homo sapiens, GI164519026, Length=591, Percent_Identity=37.5634517766497, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI208022658, Length=396, Percent_Identity=36.1111111111111, Blast_Score=193, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI72000600, Length=610, Percent_Identity=33.2786885245902, Blast_Score=300, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI17568491, Length=635, Percent_Identity=31.496062992126, Blast_Score=268, Evalue=7e-72,
Organism=Drosophila melanogaster, GI24646169, Length=594, Percent_Identity=36.1952861952862, Blast_Score=335, Evalue=5e-92,
Organism=Drosophila melanogaster, GI24582088, Length=630, Percent_Identity=32.2222222222222, Blast_Score=314, Evalue=1e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR019801
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR001944 [H]

Pfam domain/function: PF01301 Glyco_hydro_35 [H]

EC number: =3.2.1.23 [H]

Molecular weight: Translated: 67965; Mature: 67965

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS01182 GLYCOSYL_HYDROL_F35

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRTTLAPLVLALSIALPITATAASDDQWPTFATQGTQFVRDGKPYQVLSGAIHFQRIPR
CCCHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCH
TYWKDRLQKARALGLNTVETYVFWNLVEPQQGQFDFNANNDVAAFVREAAAQGLNVILRP
HHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEECCCCHHHHHHHHHHHCCCEEEECC
GPYACAEWEAGGYPAWLFGKDNIRIRSRDPRFLAASQSYLDAVAQQVRPLLNHNGGPIIA
CCCEEECCCCCCCEEEEEECCCEEEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCCEEE
VQVENEYGSYDDDHAYIADNRAMFVKAGFDKALLFTSDGADMLANGTLPGTLAVVNFAPG
EEECCCCCCCCCCCEEEECCCEEEEEECCCEEEEEECCCCHHEECCCCCCEEEEEEECCC
EAKSAFDKLIKFQPDQPRMVGEYWAGWFDHWGTPHASTNAKQQTEELEWILRQGHSANLY
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEE
MFIGGTSFGFMNGANFQGNPSDHYAPQTTSYDYDAILDEAGRPTPKFALMRDVITRVTGV
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCC
QPPALPAPIAMAALKDAPLRESASLWDNLPAPIAIDTPQPMEHFGQDYGYILYRTTVTGP
CCCCCCCHHHHHHHCCCCCCCHHHHHHCCCCCEEECCCCHHHHHCCCCCEEEEEEEECCC
RKESLYLGEVRDVARVYVDQKPVGSVERRLQQVATEVDIPAGQHTLDVLVENSGRINYGP
CCCCEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCC
RMADGRAGLVDPVLLDNQQLTNWQAFPLPMRSPDSIRGWTRNTVEGPAFHRGNLRIGTPA
CCCCCCCCCCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEECCCEEECCCC
DTYLDMRAFGKGIAWANGVNLGRHWNIGPQRALYFPAPFQRKGDNTVVVFDLDSTAKPSV
HHHHHHHHHCCCCCEECCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEECCCCCCCHH
RGLQQQVWITPKE
HCCCCEEEECCCC
>Mature Secondary Structure
MLRTTLAPLVLALSIALPITATAASDDQWPTFATQGTQFVRDGKPYQVLSGAIHFQRIPR
CCCHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCH
TYWKDRLQKARALGLNTVETYVFWNLVEPQQGQFDFNANNDVAAFVREAAAQGLNVILRP
HHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEECCCCHHHHHHHHHHHCCCEEEECC
GPYACAEWEAGGYPAWLFGKDNIRIRSRDPRFLAASQSYLDAVAQQVRPLLNHNGGPIIA
CCCEEECCCCCCCEEEEEECCCEEEECCCCCEEECCHHHHHHHHHHHHHHHCCCCCCEEE
VQVENEYGSYDDDHAYIADNRAMFVKAGFDKALLFTSDGADMLANGTLPGTLAVVNFAPG
EEECCCCCCCCCCCEEEECCCEEEEEECCCEEEEEECCCCHHEECCCCCCEEEEEEECCC
EAKSAFDKLIKFQPDQPRMVGEYWAGWFDHWGTPHASTNAKQQTEELEWILRQGHSANLY
CHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEE
MFIGGTSFGFMNGANFQGNPSDHYAPQTTSYDYDAILDEAGRPTPKFALMRDVITRVTGV
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCC
QPPALPAPIAMAALKDAPLRESASLWDNLPAPIAIDTPQPMEHFGQDYGYILYRTTVTGP
CCCCCCCHHHHHHHCCCCCCCHHHHHHCCCCCEEECCCCHHHHHCCCCCEEEEEEEECCC
RKESLYLGEVRDVARVYVDQKPVGSVERRLQQVATEVDIPAGQHTLDVLVENSGRINYGP
CCCCEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCC
RMADGRAGLVDPVLLDNQQLTNWQAFPLPMRSPDSIRGWTRNTVEGPAFHRGNLRIGTPA
CCCCCCCCCCCCEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEECCCEEECCCC
DTYLDMRAFGKGIAWANGVNLGRHWNIGPQRALYFPAPFQRKGDNTVVVFDLDSTAKPSV
HHHHHHHHHCCCCCEECCCCCCCCCCCCCCCEEECCCCCCCCCCCEEEEEECCCCCCCHH
RGLQQQVWITPKE
HCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8563148 [H]