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The map label for this gene is coaE

Identifier: 66767383

GI number: 66767383

Start: 1270957

End: 1271580

Strand: Reverse

Name: coaE

Synonym: XC_1055

Alternate gene names: 66767383

Gene position: 1271580-1270957 (Counterclockwise)

Preceding gene: 66767384

Following gene: 66767381

Centisome position: 24.7

GC content: 61.22

Gene sequence:

>624_bases
ATGAGCAACTTCATCGTCGGCCTCACCGGCGGCATCGCCTCCGGCAAAAGCGCACTTGCCGCTGAGTTCGAGAAGTTGGG
CGTGCCGGTGGTCGATGCCGATGTCGTTGCGCGGCAAGTGGTGGCGCCTGGTCTCATACTTGATGCCATCACGAACCGCT
TTGGCCAAGGCATCTTGTTGCCGGATGGCACGCTGGATCGACAGGCCTTACGCAAGATCGTCTTCGCGGATCCAACCGAG
CGGAGAGCGCTCGAAGCGATCACCCATCCTGCCATTCGCACCGAATTGCAGCGCGCGGCGAAAGCGGCCAATCACCCCTA
CGCTATCGTGGCAATCCCATTACTCGCTGAAGCAGGGGCACGGGCGACCTATCCCTGGCTCGACCGCATCCTGGTCGTCG
ACGTACCGGTTGCGCTTCAACACGCCCGCCTGATGCAACGCGACGGCAGTACGTCGGCCCTTGCCGGTCAGATGATTGCC
GCGCAGGCCTCTCGCGCACAGCGACTGGCCATCGCCGATGATGTTGTCAGTAATGAGGGCAATACGGACCAGTTGGCGCA
ACAGGCGCAACGGCTGGATGCGACTTACAGAGCGGCGCTTCAAACCCATCGAATCGAAAACTAA

Upstream 100 bases:

>100_bases
CCTTATCTGGCCATCGCCGGCTGGGTAGTGTTCTTCTGGGGTAACGACCTGGTGGATGGCTACCTGCGTTTCGCAGGCCT
GCGTTGAGCAAGCCACGACG

Downstream 100 bases:

>100_bases
CGTTTGATACTCCCGTATGCGATATGCGCCACGGCCGCACGGCCACCATCACATCGGTTAAAAATGATTTGGATGCAATG
CACGGAATCCACTATTCCTG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSNFIVGLTGGIASGKSALAAEFEKLGVPVVDADVVARQVVAPGLILDAITNRFGQGILLPDGTLDRQALRKIVFADPTE
RRALEAITHPAIRTELQRAAKAANHPYAIVAIPLLAEAGARATYPWLDRILVVDVPVALQHARLMQRDGSTSALAGQMIA
AQASRAQRLAIADDVVSNEGNTDQLAQQAQRLDATYRAALQTHRIEN

Sequences:

>Translated_207_residues
MSNFIVGLTGGIASGKSALAAEFEKLGVPVVDADVVARQVVAPGLILDAITNRFGQGILLPDGTLDRQALRKIVFADPTE
RRALEAITHPAIRTELQRAAKAANHPYAIVAIPLLAEAGARATYPWLDRILVVDVPVALQHARLMQRDGSTSALAGQMIA
AQASRAQRLAIADDVVSNEGNTDQLAQQAQRLDATYRAALQTHRIEN
>Mature_206_residues
SNFIVGLTGGIASGKSALAAEFEKLGVPVVDADVVARQVVAPGLILDAITNRFGQGILLPDGTLDRQALRKIVFADPTER
RALEAITHPAIRTELQRAAKAANHPYAIVAIPLLAEAGARATYPWLDRILVVDVPVALQHARLMQRDGSTSALAGQMIAA
QASRAQRLAIADDVVSNEGNTDQLAQQAQRLDATYRAALQTHRIEN

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=181, Percent_Identity=38.121546961326, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI191252795, Length=181, Percent_Identity=38.121546961326, Blast_Score=111, Evalue=5e-25,
Organism=Homo sapiens, GI110227607, Length=180, Percent_Identity=28.8888888888889, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1786292, Length=194, Percent_Identity=47.4226804123711, Blast_Score=161, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17554944, Length=206, Percent_Identity=33.9805825242718, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320402, Length=200, Percent_Identity=37, Blast_Score=99, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24644728, Length=202, Percent_Identity=31.6831683168317, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24658602, Length=194, Percent_Identity=32.4742268041237, Blast_Score=91, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_XANC8 (Q4UXU8)

Other databases:

- EMBL:   CP000050
- RefSeq:   YP_242145.1
- ProteinModelPortal:   Q4UXU8
- SMR:   Q4UXU8
- STRING:   Q4UXU8
- GeneID:   3382741
- GenomeReviews:   CP000050_GR
- KEGG:   xcb:XC_1055
- eggNOG:   COG0237
- HOGENOM:   HBG650290
- OMA:   IIAREVV
- PhylomeDB:   Q4UXU8
- ProtClustDB:   PRK00081
- BioCyc:   XCAM314565:XC_1055-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 22099; Mature: 21967

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS51219 DPCK; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNFIVGLTGGIASGKSALAAEFEKLGVPVVDADVVARQVVAPGLILDAITNRFGQGILL
CCCEEEEECCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHCCHHHHHHHHHHHCCEEEC
PDGTLDRQALRKIVFADPTERRALEAITHPAIRTELQRAAKAANHPYAIVAIPLLAEAGA
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCC
RATYPWLDRILVVDVPVALQHARLMQRDGSTSALAGQMIAAQASRAQRLAIADDVVSNEG
CCCCHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NTDQLAQQAQRLDATYRAALQTHRIEN
CHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SNFIVGLTGGIASGKSALAAEFEKLGVPVVDADVVARQVVAPGLILDAITNRFGQGILL
CCEEEEECCCCCCCHHHHHHHHHHCCCCEECHHHHHHHHHCCHHHHHHHHHHHCCEEEC
PDGTLDRQALRKIVFADPTERRALEAITHPAIRTELQRAAKAANHPYAIVAIPLLAEAGA
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHCCC
RATYPWLDRILVVDVPVALQHARLMQRDGSTSALAGQMIAAQASRAQRLAIADDVVSNEG
CCCCHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
NTDQLAQQAQRLDATYRAALQTHRIEN
CHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA