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The map label for this gene is blh [H]

Identifier: 66767239

GI number: 66767239

Start: 1089719

End: 1090531

Strand: Reverse

Name: blh [H]

Synonym: XC_0907

Alternate gene names: 66767239

Gene position: 1090531-1089719 (Counterclockwise)

Preceding gene: 66767240

Following gene: 66767238

Centisome position: 21.18

GC content: 66.42

Gene sequence:

>813_bases
ATGCAGCCGCAGGTCCTTGCGTTCTTCCATGCCGACAGCAACACCTTTACCTACGTGGTTGCCGATACGCGCACCGGGGC
GGCGGCGGTGATCGACCCGGCGCTGGACTACGCTGCCGACACCGGCGCGATCACCACACAGGCGGCGCAAGCCATTGTCG
ATGCCGTACAGCAGCATGGCTGGCAGGTGCAGTGGTTGTTGGAAACGCACGCACACGCCGATCACCTCAGCGCCGCGCAA
TGGTTGAAGCAGCACTGGCCGGACGCGCGAGTCGGGATCGGCGAAGGCATCACACAGGTCCAGCAGACGCTGGCGCCGCA
GTACGCATTGCCGGCCGGGTTTCGTGCCGATGGCGCGCAGTTCGACCATCTGTTTGCCGATGACGAGCGCTTCGCGTTGG
GCGCGATTGCCTGCCGCGTGATTGCAGTGCCCGGGCACACCAGCGACAGCATCGCCTACCTGATGGGCGATGCACTGTTT
CCTGGCGACTCGCTGTTCATGCCGGACGCGGGCACCGCGCGCTGCGACTTCCCCGGCGGTGACGCGCGTCAACTCTATGC
GTCGATCCAACGCTTGTACGCCTTGCCGGATGCCACGCGCGTGTTCGTGTGCCATGACTACGGCCCGGGCGGGCGCGCGA
TTGCACACGCGACCACCATCGGCGAGCAGCGCCGCAGCAATATCCATGTGCGCGATGGTGTGGACGTGGAGGCTTATGTG
GCGCAACGGCAAGCCCGCGATGCCGGCCTGCCCGAACCCAAGTTGATGGGCCCGGCGTTGCAGGCCAATCTGCAGGCGGG
CTGGCGCGGCTGA

Upstream 100 bases:

>100_bases
ACCTATCGCCCGATTGCCGAGACCCAGCTGCGTGTCGCGGGCGACCGGCTGGCCGCGCTGCTCAATGCGGCGCTGCGCAG
TCCCTGAGACGGAGATACCG

Downstream 100 bases:

>100_bases
GTGCAGTACGTGCGGCCTGCGCGCGATGCTTCTTTCGGGCCGATGGTTTTCTTCCGTTCCTAAGAACCTGTTCACGATCT
TTCCTGATCAGTGCAGACTA

Product: beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MQPQVLAFFHADSNTFTYVVADTRTGAAAVIDPALDYAADTGAITTQAAQAIVDAVQQHGWQVQWLLETHAHADHLSAAQ
WLKQHWPDARVGIGEGITQVQQTLAPQYALPAGFRADGAQFDHLFADDERFALGAIACRVIAVPGHTSDSIAYLMGDALF
PGDSLFMPDAGTARCDFPGGDARQLYASIQRLYALPDATRVFVCHDYGPGGRAIAHATTIGEQRRSNIHVRDGVDVEAYV
AQRQARDAGLPEPKLMGPALQANLQAGWRG

Sequences:

>Translated_270_residues
MQPQVLAFFHADSNTFTYVVADTRTGAAAVIDPALDYAADTGAITTQAAQAIVDAVQQHGWQVQWLLETHAHADHLSAAQ
WLKQHWPDARVGIGEGITQVQQTLAPQYALPAGFRADGAQFDHLFADDERFALGAIACRVIAVPGHTSDSIAYLMGDALF
PGDSLFMPDAGTARCDFPGGDARQLYASIQRLYALPDATRVFVCHDYGPGGRAIAHATTIGEQRRSNIHVRDGVDVEAYV
AQRQARDAGLPEPKLMGPALQANLQAGWRG
>Mature_270_residues
MQPQVLAFFHADSNTFTYVVADTRTGAAAVIDPALDYAADTGAITTQAAQAIVDAVQQHGWQVQWLLETHAHADHLSAAQ
WLKQHWPDARVGIGEGITQVQQTLAPQYALPAGFRADGAQFDHLFADDERFALGAIACRVIAVPGHTSDSIAYLMGDALF
PGDSLFMPDAGTARCDFPGGDARQLYASIQRLYALPDATRVFVCHDYGPGGRAIAHATTIGEQRRSNIHVRDGVDVEAYV
AQRQARDAGLPEPKLMGPALQANLQAGWRG

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-B beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=263, Percent_Identity=26.2357414448669, Blast_Score=89, Evalue=3e-18,
Organism=Escherichia coli, GI1787158, Length=215, Percent_Identity=27.4418604651163, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538952, Length=267, Percent_Identity=25.0936329588015, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221330176, Length=263, Percent_Identity=28.5171102661597, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005939
- InterPro:   IPR001279 [H]

Pfam domain/function: PF04273 DUF442; PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 29057; Mature: 29057

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPQVLAFFHADSNTFTYVVADTRTGAAAVIDPALDYAADTGAITTQAAQAIVDAVQQHG
CCCCEEEEEECCCCEEEEEEEECCCCCEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHCC
WQVQWLLETHAHADHLSAAQWLKQHWPDARVGIGEGITQVQQTLAPQYALPAGFRADGAQ
CEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
FDHLFADDERFALGAIACRVIAVPGHTSDSIAYLMGDALFPGDSLFMPDAGTARCDFPGG
CCCEECCCCCHHHEEEEEEEEEECCCCCCCHHHHHCCCCCCCCCEECCCCCCCCCCCCCC
DARQLYASIQRLYALPDATRVFVCHDYGPGGRAIAHATTIGEQRRSNIHVRDGVDVEAYV
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCEEEECCCCHHHHH
AQRQARDAGLPEPKLMGPALQANLQAGWRG
HHHHHHHCCCCCCHHCCHHHHHCCCCCCCC
>Mature Secondary Structure
MQPQVLAFFHADSNTFTYVVADTRTGAAAVIDPALDYAADTGAITTQAAQAIVDAVQQHG
CCCCEEEEEECCCCEEEEEEEECCCCCEEEECHHHHHCCCCCCHHHHHHHHHHHHHHHCC
WQVQWLLETHAHADHLSAAQWLKQHWPDARVGIGEGITQVQQTLAPQYALPAGFRADGAQ
CEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
FDHLFADDERFALGAIACRVIAVPGHTSDSIAYLMGDALFPGDSLFMPDAGTARCDFPGG
CCCEECCCCCHHHEEEEEEEEEECCCCCCCHHHHHCCCCCCCCCEECCCCCCCCCCCCCC
DARQLYASIQRLYALPDATRVFVCHDYGPGGRAIAHATTIGEQRRSNIHVRDGVDVEAYV
HHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEHHHHHHHHHHCCEEEECCCCHHHHH
AQRQARDAGLPEPKLMGPALQANLQAGWRG
HHHHHHHCCCCCCHHCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]