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The map label for this gene is arnT2 [H]

Identifier: 66048333

GI number: 66048333

Start: 6060139

End: 6061668

Strand: Direct

Name: arnT2 [H]

Synonym: Psyr_5109

Alternate gene names: 66048333

Gene position: 6060139-6061668 (Clockwise)

Preceding gene: 66048332

Following gene: 66048334

Centisome position: 99.45

GC content: 61.83

Gene sequence:

>1530_bases
ATGACGGTGCGAACTCACCTTTCGCCTCGCCTCGAGGGATGGCTACTGGTCGCGCTGGCCGTTTTACTGGTCGGGGGCGG
CCTGGGCTTGCGTCTGCCGCAGAACGTGGACGAAGAGCGTTTTCTCGGCGTCGCCCTGGAAATGCTGCAGAACGGCTCAT
GGTTCGTCCCGCACCGGGCCGCGCAGATTTATGCCGACAAACCGCCGCTGTTCATGTGGGCGACGGCATTCTTCATTTGG
CTGACGGGCAGCCCGAACATCGCGCTGTACCTGCCCGGGCTGCTCTCTGCAGGCGCGACCACCGCAGTCCTCTACGATCT
GGGCACCCGCCTGTGGAACCGACGCATCGGTCGGTACGCCGCCTTGCTGTTCCTGGCCACCTATCAGACCTACAGCATCC
TGCGCACCGGGCAGATCGACAGTTTTCTGTGCCTGTGGATTGCGCTGGGCTTCTACGGCCTGGTTCGCCACGTGTTGCTC
GGGCCGGCCTGGGGCTGGTTCTATTTCAGCTGTGCGGCGATGGGCCTGGGCATTATCACCAAGGGCGTCGGTTTTGTTCC
CGCGTTGATGTTGATCCCTTACGCCTATGCCGCGCGCAAAGGTTGGCAAGGTGTCGTGGCCATGCCTGGACAGGCCGCTC
GCTGGGCGCTGGGTCTGCTGGTGTTATTGCTGGCCTGCTGCCTGTGGCTGGTGCCGATGATTATCTCGGTCGTGCGTGAC
GGCGGCCCGGAAGGCTTCGCCTACGTGCAGGAAATACTCTTGCACCAGACCGCCAATCGCTACGCCAGCGCCTGGGACCA
TCGCGAGCCCTTCTGGTATTTCTTCGTCAAAGTCATCCCGCAGTATTGGCTGCCGCTGGTGCTGGTGCTGCCCTGGCTGA
TCCCGGCCTGGCGCCGACAGTTGGGCAAGCACGATGGCCGGGTGTTGGTACTGCTCGGCTGGGTGTTGCTGGTGCTGCTG
TTCTTCAGCCTCTCCAGTGGCAAACGCAAGATCTACATCTTTCCGGCGCTGCCCGGCCTGGTACTGGTAGCCGCCCCCTT
GCTGCCTTGGTTATTGAAACGCTGGTTCCATGACCGCATACGGGCTCGGCGAATCGTCCCGGTGGTGGTGGTTGTCTGGC
TTGGTCTGTGGTTCGCCAGAGGGTTCGTCGAACCCTTTATAGAGGGCCAAAACCCACACAAGGAACTGATGGAACAGGCC
GCTTACGTCACTCAAGGTGCCGATCTGGTGCTGATCAACTGGCGCGAGGGGCACTGGCTCTATGCACGCCAACCCATTGT
GCATTTCGGTTTTGCCAAGCCGTCGGCAACCGAACAGGCCGCCCGCTGGCTAAGAGAACACCCCGGCACCTTTGCGCTGG
TGCCAGGCGAGCAACTGGCCAATTGCTTCTTGCCGGAAAAAGCCCGGCCGCTGGGCCAGACCTCCAGAGCTGACTGGTTC
ATCGTCGATGCCGATGCCGACAACGGCCGGTGTAAACCGCAACGCCCTATGCAGGCCTATCGCTTCGCCTGGCAGCAGAA
TGTTGATTAA

Upstream 100 bases:

>100_bases
GACAGGACCCGGTCTTCATCGCCGGCCAGGCCTTTGGCCTGCTGGTGTACATGCGTAACCTGCAGCTGATCAGCCGACAG
GCCAAGACACCTGAGGAGCA

Downstream 100 bases:

>100_bases
TCCCCCGCCCAGCCGCCCAACACGCGGGAGTGCCTGACGCCATGCAACTGGAAACGATCAAGGCAAAGCGCTTGACGTGG
TCGAACGTCGCTCGAAGGCA

Product: glycosyl transferase family protein

Products: NA

Alternate protein names: 4-amino-4-deoxy-L-arabinose lipid A transferase 2; Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase; Undecaprenyl phosphate-alpha-L-Ara4N transferase 2 [H]

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MTVRTHLSPRLEGWLLVALAVLLVGGGLGLRLPQNVDEERFLGVALEMLQNGSWFVPHRAAQIYADKPPLFMWATAFFIW
LTGSPNIALYLPGLLSAGATTAVLYDLGTRLWNRRIGRYAALLFLATYQTYSILRTGQIDSFLCLWIALGFYGLVRHVLL
GPAWGWFYFSCAAMGLGIITKGVGFVPALMLIPYAYAARKGWQGVVAMPGQAARWALGLLVLLLACCLWLVPMIISVVRD
GGPEGFAYVQEILLHQTANRYASAWDHREPFWYFFVKVIPQYWLPLVLVLPWLIPAWRRQLGKHDGRVLVLLGWVLLVLL
FFSLSSGKRKIYIFPALPGLVLVAAPLLPWLLKRWFHDRIRARRIVPVVVVVWLGLWFARGFVEPFIEGQNPHKELMEQA
AYVTQGADLVLINWREGHWLYARQPIVHFGFAKPSATEQAARWLREHPGTFALVPGEQLANCFLPEKARPLGQTSRADWF
IVDADADNGRCKPQRPMQAYRFAWQQNVD

Sequences:

>Translated_509_residues
MTVRTHLSPRLEGWLLVALAVLLVGGGLGLRLPQNVDEERFLGVALEMLQNGSWFVPHRAAQIYADKPPLFMWATAFFIW
LTGSPNIALYLPGLLSAGATTAVLYDLGTRLWNRRIGRYAALLFLATYQTYSILRTGQIDSFLCLWIALGFYGLVRHVLL
GPAWGWFYFSCAAMGLGIITKGVGFVPALMLIPYAYAARKGWQGVVAMPGQAARWALGLLVLLLACCLWLVPMIISVVRD
GGPEGFAYVQEILLHQTANRYASAWDHREPFWYFFVKVIPQYWLPLVLVLPWLIPAWRRQLGKHDGRVLVLLGWVLLVLL
FFSLSSGKRKIYIFPALPGLVLVAAPLLPWLLKRWFHDRIRARRIVPVVVVVWLGLWFARGFVEPFIEGQNPHKELMEQA
AYVTQGADLVLINWREGHWLYARQPIVHFGFAKPSATEQAARWLREHPGTFALVPGEQLANCFLPEKARPLGQTSRADWF
IVDADADNGRCKPQRPMQAYRFAWQQNVD
>Mature_508_residues
TVRTHLSPRLEGWLLVALAVLLVGGGLGLRLPQNVDEERFLGVALEMLQNGSWFVPHRAAQIYADKPPLFMWATAFFIWL
TGSPNIALYLPGLLSAGATTAVLYDLGTRLWNRRIGRYAALLFLATYQTYSILRTGQIDSFLCLWIALGFYGLVRHVLLG
PAWGWFYFSCAAMGLGIITKGVGFVPALMLIPYAYAARKGWQGVVAMPGQAARWALGLLVLLLACCLWLVPMIISVVRDG
GPEGFAYVQEILLHQTANRYASAWDHREPFWYFFVKVIPQYWLPLVLVLPWLIPAWRRQLGKHDGRVLVLLGWVLLVLLF
FSLSSGKRKIYIFPALPGLVLVAAPLLPWLLKRWFHDRIRARRIVPVVVVVWLGLWFARGFVEPFIEGQNPHKELMEQAA
YVTQGADLVLINWREGHWLYARQPIVHFGFAKPSATEQAARWLREHPGTFALVPGEQLANCFLPEKARPLGQTSRADWFI
VDADADNGRCKPQRPMQAYRFAWQQNVD

Specific function: Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG1807

COG function: function code M; 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 83 family [H]

Homologues:

Organism=Escherichia coli, GI1788591, Length=329, Percent_Identity=27.6595744680851, Blast_Score=92, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022839
- InterPro:   IPR003342 [H]

Pfam domain/function: PF02366 PMT [H]

EC number: =2.4.2.43 [H]

Molecular weight: Translated: 57681; Mature: 57550

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRTHLSPRLEGWLLVALAVLLVGGGLGLRLPQNVDEERFLGVALEMLQNGSWFVPHRA
CCEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCHH
AQIYADKPPLFMWATAFFIWLTGSPNIALYLPGLLSAGATTAVLYDLGTRLWNRRIGRYA
HHHCCCCCCHHHHHHHHHEEECCCCCEEEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHH
ALLFLATYQTYSILRTGQIDSFLCLWIALGFYGLVRHVLLGPAWGWFYFSCAAMGLGIIT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
KGVGFVPALMLIPYAYAARKGWQGVVAMPGQAARWALGLLVLLLACCLWLVPMIISVVRD
HCHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGPEGFAYVQEILLHQTANRYASAWDHREPFWYFFVKVIPQYWLPLVLVLPWLIPAWRRQ
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGKHDGRVLVLLGWVLLVLLFFSLSSGKRKIYIFPALPGLVLVAAPLLPWLLKRWFHDRI
HCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHH
RARRIVPVVVVVWLGLWFARGFVEPFIEGQNPHKELMEQAAYVTQGADLVLINWREGHWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEE
YARQPIVHFGFAKPSATEQAARWLREHPGTFALVPGEQLANCFLPEKARPLGQTSRADWF
EECCCCCEECCCCCCCHHHHHHHHHHCCCCEEEECHHHHHHCCCCCCCCCCCCCCCCCEE
IVDADADNGRCKPQRPMQAYRFAWQQNVD
EEECCCCCCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
TVRTHLSPRLEGWLLVALAVLLVGGGLGLRLPQNVDEERFLGVALEMLQNGSWFVPHRA
CEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEECCCHH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EEECCCCCCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA