Click here to switch to the map view.

The map label for this gene is lpxB [H]

Identifier: 66048332

GI number: 66048332

Start: 6059858

End: 6060142

Strand: Direct

Name: lpxB [H]

Synonym: Psyr_5108

Alternate gene names: 66048332

Gene position: 6059858-6060142 (Clockwise)

Preceding gene: 66048331

Following gene: 66048333

Centisome position: 99.44

GC content: 57.89

Gene sequence:

>285_bases
ATGAAGCCGGACAACGAGACTTTCTGGCTGATCCTCGGCTTTGTCGGGCAGGCGGTTTTTACCGGCCGCTTTGTCCTGCA
ATGGCTGTACAGCGAATTCAAGAAGCGCAGCATCATCCCGGTAGGCTTCTGGTACCTGAGCATGCTGGGCAGCACGATCC
TGCTGGCCTACGCCATTTATCGACAGGACCCGGTCTTCATCGCCGGCCAGGCCTTTGGCCTGCTGGTGTACATGCGTAAC
CTGCAGCTGATCAGCCGACAGGCCAAGACACCTGAGGAGCAATGA

Upstream 100 bases:

>100_bases
GCAACCTGGACCGCGCGCTGGTGGGCATTCTTGATCTGGTCGGCGTCTGGTGGCTGATCCGTCGGACTCGCCTGGATGTT
CAGGCACAGGAACTGCGGCC

Downstream 100 bases:

>100_bases
CGGTGCGAACTCACCTTTCGCCTCGCCTCGAGGGATGGCTACTGGTCGCGCTGGCCGTTTTACTGGTCGGGGGCGGCCTG
GGCTTGCGTCTGCCGCAGAA

Product: Lipid A biosynthesis, N-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 94; Mature: 94

Protein sequence:

>94_residues
MKPDNETFWLILGFVGQAVFTGRFVLQWLYSEFKKRSIIPVGFWYLSMLGSTILLAYAIYRQDPVFIAGQAFGLLVYMRN
LQLISRQAKTPEEQ

Sequences:

>Translated_94_residues
MKPDNETFWLILGFVGQAVFTGRFVLQWLYSEFKKRSIIPVGFWYLSMLGSTILLAYAIYRQDPVFIAGQAFGLLVYMRN
LQLISRQAKTPEEQ
>Mature_94_residues
MKPDNETFWLILGFVGQAVFTGRFVLQWLYSEFKKRSIIPVGFWYLSMLGSTILLAYAIYRQDPVFIAGQAFGLLVYMRN
LQLISRQAKTPEEQ

Specific function: Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG3952

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the lpxB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003835
- InterPro:   IPR011499
- ProDom:   PD339292 [H]

Pfam domain/function: PF07578 LAB_N; PF02684 LpxB [H]

EC number: =2.4.1.182 [H]

Molecular weight: Translated: 10928; Mature: 10928

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPDNETFWLILGFVGQAVFTGRFVLQWLYSEFKKRSIIPVGFWYLSMLGSTILLAYAIY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RQDPVFIAGQAFGLLVYMRNLQLISRQAKTPEEQ
HCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKPDNETFWLILGFVGQAVFTGRFVLQWLYSEFKKRSIIPVGFWYLSMLGSTILLAYAIY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
RQDPVFIAGQAFGLLVYMRNLQLISRQAKTPEEQ
HCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA