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The map label for this gene is alsT [H]

Identifier: 66048276

GI number: 66048276

Start: 5993786

End: 5995237

Strand: Direct

Name: alsT [H]

Synonym: Psyr_5052

Alternate gene names: 66048276

Gene position: 5993786-5995237 (Clockwise)

Preceding gene: 66048275

Following gene: 66048277

Centisome position: 98.36

GC content: 59.44

Gene sequence:

>1452_bases
ATGCTGGAAATGATTAACGACTTTCTCTCCGGTAAGGTACTGATCGTCCTTATCGTAGGCCTGGGTAGTTACTTCACGAT
CCGCTCGCGTTTCGTTCAGTTTCGACACTTTTTCCACATGTTCTCGGTTTTTCGCGACAGTCTGCGCAGCAGCGCGGGAC
AATTGAGTTCGTTTCAGGCCCTGATGCTCAGCCTGGCGGGCCGCGTCGGTGCCGGTAACATCGCAGGCGTCGGCATTGCC
GTGACGCTCGGCGGGCCGGGTGCCGTGTTCTGGATGTGGGTGACCGCACTGGTCGGCATGGCCAGCAGCTTCATCGAGTG
TTCACTCGCTCAGCTCTACAAGCGCAAGGATACCGAAGGCCAGTTCCGTGGCGGTCCGGCGTTCTACATCCAGCACGGTC
TGGGCAAGCGCTGGCTGGGCATGGTCATGGCCGTACTGCTGCTGGTGACCTTCGGTTTTGCTTTCAACGGCCTGCAATCG
CACGCTGTGACCGACTCGCTGAAAAGCGCGTTCAACGTCGACACCCGAACCACCGGCATCTGCCTGGTCGTACTGCTGGG
CCTGGCGTTCATCGGCGGCATCAAGCGTATCGCGGCGATTTCCGACCTGCTGGTTCCGGTCAAGACCCTGATCTACATCG
CGGTCACCATCTACGTCATCGTCCTGCAGATCGACCACGTTCCCGGCATGCTTATGACGATCGTCAGAAGCGCCTTCGGC
CTTGATCCGGTCTTCGGCGGCCTGATCGGCAGCGCGATCGTGATGGGCGTCAAACGTGGCGTCTTCGCCAACGAAGCCGG
TCTGGGCAGTGCGCCCAACGTGGCTGCCGTGGCACAGGTCGAGCACCCGGTGGCACAGGGCGTGGTTCAGGCGTTCAGCG
TGTTCCTCGACACCTTCGTGATCTGCACCTGCACCGCCTTGCTGATTCTTCTGTCCGGTATATACGACATCGGCTACGAC
GGCAACGGCATCGTTCTGGCACAGAACTCGCTGGCAGCCGTGGTCGGAGACTGGGGCCGGGTGTTTATCAGCGTAGCGCT
GGCACTGTTCGTCTTCACCTCGATTCTCTACAACTACTACTTGGGCGAAAACAGCCTGCGGTTCCTGTTTGGCGAGAAGA
TGCAGACCATCATCATCTACCGCATCGCGGTACTGGTATTGATCATGTGGGGTGCCGTCGTCGACCTGAAAGATGTACTG
GCATTCGCCGACATCACCATGACCATGCTGGCGTTCGTCAACCTGATCGCCCTCGCCATGCTGTTCAAAGTCGTCAAGCG
CATTTTGAATGACTACGATGCGCAACGTCGGGCCGGGGTCAAGACGCCGGTGTTCGATTCCAGTCAGTTCCCTGATCTGG
ACCTGGACCGCAACGCATGGCCAGCCAATCCGACCCGTCAGTCGACGCAGGATGCCGAAGCGGCAGCCAAGCCTGCGCCC
GAAGCACGATAA

Upstream 100 bases:

>100_bases
GTCGCGAATGAAGAATCAGCCGTCCAAGAAAGCGACTACAGACGTAAAAACTTTGCACCGGTATAGTGCGCCCCCTCAAA
AGTAGCGAGGAATAACAAAA

Downstream 100 bases:

>100_bases
CCACCGCGACACTACGCCGGAGAAGAGCCATGCCTGATGACGCACAACAACCCGCCCAACGCGTGATGGTTCTTTACACC
GGCGGCACCATCGGCATGCA

Product: Sodium:alanine symporter

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MLEMINDFLSGKVLIVLIVGLGSYFTIRSRFVQFRHFFHMFSVFRDSLRSSAGQLSSFQALMLSLAGRVGAGNIAGVGIA
VTLGGPGAVFWMWVTALVGMASSFIECSLAQLYKRKDTEGQFRGGPAFYIQHGLGKRWLGMVMAVLLLVTFGFAFNGLQS
HAVTDSLKSAFNVDTRTTGICLVVLLGLAFIGGIKRIAAISDLLVPVKTLIYIAVTIYVIVLQIDHVPGMLMTIVRSAFG
LDPVFGGLIGSAIVMGVKRGVFANEAGLGSAPNVAAVAQVEHPVAQGVVQAFSVFLDTFVICTCTALLILLSGIYDIGYD
GNGIVLAQNSLAAVVGDWGRVFISVALALFVFTSILYNYYLGENSLRFLFGEKMQTIIIYRIAVLVLIMWGAVVDLKDVL
AFADITMTMLAFVNLIALAMLFKVVKRILNDYDAQRRAGVKTPVFDSSQFPDLDLDRNAWPANPTRQSTQDAEAAAKPAP
EAR

Sequences:

>Translated_483_residues
MLEMINDFLSGKVLIVLIVGLGSYFTIRSRFVQFRHFFHMFSVFRDSLRSSAGQLSSFQALMLSLAGRVGAGNIAGVGIA
VTLGGPGAVFWMWVTALVGMASSFIECSLAQLYKRKDTEGQFRGGPAFYIQHGLGKRWLGMVMAVLLLVTFGFAFNGLQS
HAVTDSLKSAFNVDTRTTGICLVVLLGLAFIGGIKRIAAISDLLVPVKTLIYIAVTIYVIVLQIDHVPGMLMTIVRSAFG
LDPVFGGLIGSAIVMGVKRGVFANEAGLGSAPNVAAVAQVEHPVAQGVVQAFSVFLDTFVICTCTALLILLSGIYDIGYD
GNGIVLAQNSLAAVVGDWGRVFISVALALFVFTSILYNYYLGENSLRFLFGEKMQTIIIYRIAVLVLIMWGAVVDLKDVL
AFADITMTMLAFVNLIALAMLFKVVKRILNDYDAQRRAGVKTPVFDSSQFPDLDLDRNAWPANPTRQSTQDAEAAAKPAP
EAR
>Mature_483_residues
MLEMINDFLSGKVLIVLIVGLGSYFTIRSRFVQFRHFFHMFSVFRDSLRSSAGQLSSFQALMLSLAGRVGAGNIAGVGIA
VTLGGPGAVFWMWVTALVGMASSFIECSLAQLYKRKDTEGQFRGGPAFYIQHGLGKRWLGMVMAVLLLVTFGFAFNGLQS
HAVTDSLKSAFNVDTRTTGICLVVLLGLAFIGGIKRIAAISDLLVPVKTLIYIAVTIYVIVLQIDHVPGMLMTIVRSAFG
LDPVFGGLIGSAIVMGVKRGVFANEAGLGSAPNVAAVAQVEHPVAQGVVQAFSVFLDTFVICTCTALLILLSGIYDIGYD
GNGIVLAQNSLAAVVGDWGRVFISVALALFVFTSILYNYYLGENSLRFLFGEKMQTIIIYRIAVLVLIMWGAVVDLKDVL
AFADITMTMLAFVNLIALAMLFKVVKRILNDYDAQRRAGVKTPVFDSSQFPDLDLDRNAWPANPTRQSTQDAEAAAKPAP
EAR

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=466, Percent_Identity=42.7038626609442, Blast_Score=354, Evalue=9e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 52186; Mature: 52186

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS00873 NA_ALANINE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCC
>Mature Secondary Structure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CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969507; 9384377; 7710280 [H]