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The map label for this gene is pfpI [H]

Identifier: 66047987

GI number: 66047987

Start: 5638071

End: 5638610

Strand: Direct

Name: pfpI [H]

Synonym: Psyr_4763

Alternate gene names: 66047987

Gene position: 5638071-5638610 (Clockwise)

Preceding gene: 66047983

Following gene: 66047988

Centisome position: 92.52

GC content: 55.56

Gene sequence:

>540_bases
ATGTCTAAAGCATTGACTGGCAAACGCATAGCAATTCTTGTAACCGACGGTTTCGAACAGGTTGAACTGACCGGTCCGAA
AGAAGCGCTGGAGCAAGCAGGCGCCACCGTGGAAATCCTTTCCGCTGAAGAGGGCAAGGTCAAAGGCTGGAATCACGACA
AACCTGCCGATGACTTCAAGATCGACGGCACGTTCAAGGCTGCCAATGCCAGTGACTACCATGGTGTGGTGCTGCCGGGC
GGAGTACAGAACTCAGACACCATCCGCATAGACAGCGACGCGCAGAAGATCGTCAAGGACATCGAGGCCGCGGGCAAGCC
GGTGGCGGTTATCTGCCATGGCAGCTGGCTGTTGATCTCGGCAGGACTGGTAAAAGGTAAAACCCTGACCAGCTTCAAGA
CGCTGAAAGATGACCTGGTCAATGCTGGCGCGAAATGGGTCGATCAGGAAGTCGTCACCGACGGCAAACTGATCAGCAGC
CGTCAACCCGACGACATCCCCGCGTTCAACAGCAAACTGATCGAAGCACTGTCTGCCTGA

Upstream 100 bases:

>100_bases
TTGCCTGGTACGAAGCTTCGGACTCTGTGTTAACGGCGTGAACGGCGGCTGCAAAACGGCCTGCCAGACGCTACTTTTAA
GCCCGACACTGGAGGATCCC

Downstream 100 bases:

>100_bases
CAGATTCCGTCAGTTAATTGCAGTCATCCCGGCCCAGCGCCGGGATGACGCGCTATAATCCCGCTCTTTTTTCAGGAGCG
ACGTCATGTCCCTGCCTAGC

Product: peptidase C56, PfpI

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MSKALTGKRIAILVTDGFEQVELTGPKEALEQAGATVEILSAEEGKVKGWNHDKPADDFKIDGTFKAANASDYHGVVLPG
GVQNSDTIRIDSDAQKIVKDIEAAGKPVAVICHGSWLLISAGLVKGKTLTSFKTLKDDLVNAGAKWVDQEVVTDGKLISS
RQPDDIPAFNSKLIEALSA

Sequences:

>Translated_179_residues
MSKALTGKRIAILVTDGFEQVELTGPKEALEQAGATVEILSAEEGKVKGWNHDKPADDFKIDGTFKAANASDYHGVVLPG
GVQNSDTIRIDSDAQKIVKDIEAAGKPVAVICHGSWLLISAGLVKGKTLTSFKTLKDDLVNAGAKWVDQEVVTDGKLISS
RQPDDIPAFNSKLIEALSA
>Mature_178_residues
SKALTGKRIAILVTDGFEQVELTGPKEALEQAGATVEILSAEEGKVKGWNHDKPADDFKIDGTFKAANASDYHGVVLPGG
VQNSDTIRIDSDAQKIVKDIEAAGKPVAVICHGSWLLISAGLVKGKTLTSFKTLKDDLVNAGAKWVDQEVVTDGKLISSR
QPDDIPAFNSKLIEALSA

Specific function: Highly stable protease. Although the physiological function is unclear it is the dominant protease in P.furiosus [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Escherichia coli, GI87082219, Length=174, Percent_Identity=39.6551724137931, Blast_Score=122, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28571932, Length=173, Percent_Identity=29.4797687861272, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 18998; Mature: 18866

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKALTGKRIAILVTDGFEQVELTGPKEALEQAGATVEILSAEEGKVKGWNHDKPADDFK
CCCCCCCCEEEEEEECCCCEEEECCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEE
IDGTFKAANASDYHGVVLPGGVQNSDTIRIDSDAQKIVKDIEAAGKPVAVICHGSWLLIS
ECCEEEECCCCCCCCEEECCCCCCCCEEEECCHHHHHHHHHHHCCCCEEEEEECCEEEEE
AGLVKGKTLTSFKTLKDDLVNAGAKWVDQEVVTDGKLISSRQPDDIPAFNSKLIEALSA
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SKALTGKRIAILVTDGFEQVELTGPKEALEQAGATVEILSAEEGKVKGWNHDKPADDFK
CCCCCCCEEEEEEECCCCEEEECCHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEE
IDGTFKAANASDYHGVVLPGGVQNSDTIRIDSDAQKIVKDIEAAGKPVAVICHGSWLLIS
ECCEEEECCCCCCCCEEECCCCCCCCEEEECCHHHHHHHHHHHCCCCEEEEEECCEEEEE
AGLVKGKTLTSFKTLKDDLVNAGAKWVDQEVVTDGKLISSRQPDDIPAFNSKLIEALSA
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCEEECCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8626329 [H]