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The map label for this gene is surA [H]

Identifier: 66047852

GI number: 66047852

Start: 5485325

End: 5486653

Strand: Direct

Name: surA [H]

Synonym: Psyr_4625

Alternate gene names: 66047852

Gene position: 5485325-5486653 (Clockwise)

Preceding gene: 66047851

Following gene: 66047853

Centisome position: 90.02

GC content: 58.47

Gene sequence:

>1329_bases
GTGAACGTGAAGACCAAGCTTTCTGATTGTCTGCGCCCGCTGATGCTGGGCGCGTTACTCCTGAGCGGTGCAGTGCATGC
TGCGGTTCAACCTCTGGACAGTGTCGTGGCCATCGTCGACAACGACGTGATCATGAAAAGCCAGATGGACCAGCGTGTAC
GTGAAGTTCAGCAGACCATTGCCAAGCGTGGCTCTGGTGTACCGCCTGCCGAAGCCCTGCAACCACAGGTTCTGGATCGT
CTGATTCTGGAAAACCTGCAGTTGCAGATGGGCGAACGGTCTGGCATTCGAGTCTCCGACGAAGAGCTGAACCAGGCCAT
CGGCACCATTGCCCAGCGCAACAACATGAGCGTGGAGCAGTTCCGCGCCGCGCTGGCGCATGACGGCCTGTCCTATAACG
ATGCGCGCGAACAGGTGCGCCGGGAAATGATCATCAGCCGCGTGCGTCAGCGCCGGGTGGCCGAACGTATCCAGGTGTCC
CAGCAGGAAGTGAAGAACTTCCTCGCCTCCGATATGGGCAAGGCTCAGCTGTCTGAAGAGTTTCACCTGGCCAACATTCT
GATCGCCACACCTGACAGCGCTTCTTCGGACGCCATCCAGGCCGCAGCGGTCAAGGCCAAGGGTATCTACGACCAGCTGA
AGAAAGGTGCTGACTTCACCCGTCTTGCAGCCACCTCCTCGTCCAGCGAAAACGCACTGGAAGGCGGCGACATGGGCTGG
CGCAAGGCTGCACAGTTGCCACCACCCTTCGGCGACATGCTCAGCTCGATGCCGGTCGGTGACGTAACGCCTCCTGCGCG
TACGCCGGGTGGTTTCATCATTCTCAAGCTGTTGGAAAAGCGTGGCGGTCAGGGTCAGGCGCAAATGCGTGATGAAGTGC
ATGTGCGTCATATCCTGATCAAGCCAAGCGAAATCCGTAATGAGGAAGAGACCAAGCGTCTTGCCCAGAAGATCTACGAC
CGCATCGAGAACGGCGAAGATTTCGCCGAGCTGGCGAAAAGCTTTTCGGAAGATCCGGGTTCTGCACTCAATGGCGGCGA
TCTGAACTGGGTTGATCCCAATTCTCTGGTTCCGGAATTCCGTCAGGTCATGAGCGAAACACCACAAGGCGTCTTGTCCA
AACCGTTCCAGACCCAGTACGGCTGGCATGTCCTCGAAGTGCTCGGTCGTCGCTCCACGGACGCTACCGATCAGGCTCGC
GAACAGCAGGCGCTGAACGTACTGCGTAACCGCAAGTACGACGAAGAGCTGCAAACCTGGCTGCGTCAGATCCGCGACGA
AGCCTACGTTGAAATCAAACTCCCTGGCGCGACCCAGGCTGCACAGTGA

Upstream 100 bases:

>100_bases
GGCGACCGCGGCATATTCCTACAAATCGTGTTGAAGGGGCTCGGCGGTGTAACTGGCGCCAAGGTAGACAGCTTCCTCGA
CAAAGGCATCCAAGGTTATC

Downstream 100 bases:

>100_bases
AACCCAAGCGTTTCGCACTGACACCCGGCGAGCCGGCCGGCATAGGTCCTGACCTTTGCCTGCTGCTCGCCACGCAGCCT
CAGCCATACCCCCTGATTGC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MNVKTKLSDCLRPLMLGALLLSGAVHAAVQPLDSVVAIVDNDVIMKSQMDQRVREVQQTIAKRGSGVPPAEALQPQVLDR
LILENLQLQMGERSGIRVSDEELNQAIGTIAQRNNMSVEQFRAALAHDGLSYNDAREQVRREMIISRVRQRRVAERIQVS
QQEVKNFLASDMGKAQLSEEFHLANILIATPDSASSDAIQAAAVKAKGIYDQLKKGADFTRLAATSSSSENALEGGDMGW
RKAAQLPPPFGDMLSSMPVGDVTPPARTPGGFIILKLLEKRGGQGQAQMRDEVHVRHILIKPSEIRNEEETKRLAQKIYD
RIENGEDFAELAKSFSEDPGSALNGGDLNWVDPNSLVPEFRQVMSETPQGVLSKPFQTQYGWHVLEVLGRRSTDATDQAR
EQQALNVLRNRKYDEELQTWLRQIRDEAYVEIKLPGATQAAQ

Sequences:

>Translated_442_residues
MNVKTKLSDCLRPLMLGALLLSGAVHAAVQPLDSVVAIVDNDVIMKSQMDQRVREVQQTIAKRGSGVPPAEALQPQVLDR
LILENLQLQMGERSGIRVSDEELNQAIGTIAQRNNMSVEQFRAALAHDGLSYNDAREQVRREMIISRVRQRRVAERIQVS
QQEVKNFLASDMGKAQLSEEFHLANILIATPDSASSDAIQAAAVKAKGIYDQLKKGADFTRLAATSSSSENALEGGDMGW
RKAAQLPPPFGDMLSSMPVGDVTPPARTPGGFIILKLLEKRGGQGQAQMRDEVHVRHILIKPSEIRNEEETKRLAQKIYD
RIENGEDFAELAKSFSEDPGSALNGGDLNWVDPNSLVPEFRQVMSETPQGVLSKPFQTQYGWHVLEVLGRRSTDATDQAR
EQQALNVLRNRKYDEELQTWLRQIRDEAYVEIKLPGATQAAQ
>Mature_442_residues
MNVKTKLSDCLRPLMLGALLLSGAVHAAVQPLDSVVAIVDNDVIMKSQMDQRVREVQQTIAKRGSGVPPAEALQPQVLDR
LILENLQLQMGERSGIRVSDEELNQAIGTIAQRNNMSVEQFRAALAHDGLSYNDAREQVRREMIISRVRQRRVAERIQVS
QQEVKNFLASDMGKAQLSEEFHLANILIATPDSASSDAIQAAAVKAKGIYDQLKKGADFTRLAATSSSSENALEGGDMGW
RKAAQLPPPFGDMLSSMPVGDVTPPARTPGGFIILKLLEKRGGQGQAQMRDEVHVRHILIKPSEIRNEEETKRLAQKIYD
RIENGEDFAELAKSFSEDPGSALNGGDLNWVDPNSLVPEFRQVMSETPQGVLSKPFQTQYGWHVLEVLGRRSTDATDQAR
EQQALNVLRNRKYDEELQTWLRQIRDEAYVEIKLPGATQAAQ

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=422, Percent_Identity=40.0473933649289, Blast_Score=314, Evalue=8e-87,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 49035; Mature: 49035

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVKTKLSDCLRPLMLGALLLSGAVHAAVQPLDSVVAIVDNDVIMKSQMDQRVREVQQTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AKRGSGVPPAEALQPQVLDRLILENLQLQMGERSGIRVSDEELNQAIGTIAQRNNMSVEQ
HHCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHH
FRAALAHDGLSYNDAREQVRREMIISRVRQRRVAERIQVSQQEVKNFLASDMGKAQLSEE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
FHLANILIATPDSASSDAIQAAAVKAKGIYDQLKKGADFTRLAATSSSSENALEGGDMGW
HHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCH
RKAAQLPPPFGDMLSSMPVGDVTPPARTPGGFIILKLLEKRGGQGQAQMRDEVHVRHILI
HHHCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHEE
KPSEIRNEEETKRLAQKIYDRIENGEDFAELAKSFSEDPGSALNGGDLNWVDPNSLVPEF
CCHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
RQVMSETPQGVLSKPFQTQYGWHVLEVLGRRSTDATDQAREQQALNVLRNRKYDEELQTW
HHHHHHCCHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
LRQIRDEAYVEIKLPGATQAAQ
HHHHCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MNVKTKLSDCLRPLMLGALLLSGAVHAAVQPLDSVVAIVDNDVIMKSQMDQRVREVQQTI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AKRGSGVPPAEALQPQVLDRLILENLQLQMGERSGIRVSDEELNQAIGTIAQRNNMSVEQ
HHCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHH
FRAALAHDGLSYNDAREQVRREMIISRVRQRRVAERIQVSQQEVKNFLASDMGKAQLSEE
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
FHLANILIATPDSASSDAIQAAAVKAKGIYDQLKKGADFTRLAATSSSSENALEGGDMGW
HHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCH
RKAAQLPPPFGDMLSSMPVGDVTPPARTPGGFIILKLLEKRGGQGQAQMRDEVHVRHILI
HHHCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHEE
KPSEIRNEEETKRLAQKIYDRIENGEDFAELAKSFSEDPGSALNGGDLNWVDPNSLVPEF
CCHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
RQVMSETPQGVLSKPFQTQYGWHVLEVLGRRSTDATDQAREQQALNVLRNRKYDEELQTW
HHHHHHCCHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
LRQIRDEAYVEIKLPGATQAAQ
HHHHCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA