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The map label for this gene is suhB [C]

Identifier: 66047734

GI number: 66047734

Start: 5371105

End: 5371848

Strand: Direct

Name: suhB [C]

Synonym: Psyr_4507

Alternate gene names: 66047734

Gene position: 5371105-5371848 (Clockwise)

Preceding gene: 66047733

Following gene: 66047735

Centisome position: 88.14

GC content: 61.83

Gene sequence:

>744_bases
ATGAACAACCGACTCAGCGTCGCCATGCACGCCGTAGAACAGGCCACTGGCCTGGCCATGGCGTATTTTAACGACCGCCA
CACCCTCGACATCACCACCAAAAGCGCGCAAGACCTCGTCTCCCGCGCCGACTTTGAAGTGGAACAACTGCTGCGTGCAG
AACTGAGCAAACACTTCCCCGACGATACAATCCTCGGCGAAGAAATGGGCGGCGAGTTCATCACCGATGGCTGGGTCATC
GATCCCATCGACGGCACCGGTAACTACCTGCGCGGCACCCCATTGTGGGGAATCGCGGTGGCGTACATGTCGGCAGGCGA
GCCCGAAATCGGCGTCGTCGCCTACCCGGCACTGGGCTATACCCTGGCAGCCCGCACGGGCGATGGCTTGCTGCGCAACG
GTGTCCCCTTTGTCCGCCCGCAACCACCCGAGCACCTGCGCATCGCCGGCGTTGGCGAAAACACCCGCTGGGACGCCGAA
GAGATGGGCAAACTGCACCTGAGCCTGCGCCGCCAGGGCTGGGGCCTTGCCGGTTATCGCTGCGCCACCATCGGCCTGGC
GTTCGCCGCTTTGGGGCAAACGGACGGCTACATGGAGAAATTCACCAGCCTGTGGGACATCGCAGCAGGTGCAGTGATTT
GCCGGGAAGCCGGATTGTTGTGCACGATTGAAGGCGAACAGAAACAAGGCTCGATGACGGTGATGGTAGGCCGTGAGGAG
CTGATGGGGATTTTTGGTGCGTAA

Upstream 100 bases:

>100_bases
ACAGCCCGAAACGTGCGCGCTACCTGCTAGAACATGGCGCACAGTCGATTCTCAGTGATTACCCGGACTTGTTGAACCTG
CCGAACGGAGGCTGTCTGCA

Downstream 100 bases:

>100_bases
TGCGCCGTGCTAGTCGACGCAGTTTTCTGACTGCGTTTGTCCGCCTGCTGGCGTGCCTGCCCTTTGTGAACAGCAGGCTG
CTGGCGGCAGAAACCTTTAC

Product: inositol monophosphatase

Products: myo-Inositol; Phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MNNRLSVAMHAVEQATGLAMAYFNDRHTLDITTKSAQDLVSRADFEVEQLLRAELSKHFPDDTILGEEMGGEFITDGWVI
DPIDGTGNYLRGTPLWGIAVAYMSAGEPEIGVVAYPALGYTLAARTGDGLLRNGVPFVRPQPPEHLRIAGVGENTRWDAE
EMGKLHLSLRRQGWGLAGYRCATIGLAFAALGQTDGYMEKFTSLWDIAAGAVICREAGLLCTIEGEQKQGSMTVMVGREE
LMGIFGA

Sequences:

>Translated_247_residues
MNNRLSVAMHAVEQATGLAMAYFNDRHTLDITTKSAQDLVSRADFEVEQLLRAELSKHFPDDTILGEEMGGEFITDGWVI
DPIDGTGNYLRGTPLWGIAVAYMSAGEPEIGVVAYPALGYTLAARTGDGLLRNGVPFVRPQPPEHLRIAGVGENTRWDAE
EMGKLHLSLRRQGWGLAGYRCATIGLAFAALGQTDGYMEKFTSLWDIAAGAVICREAGLLCTIEGEQKQGSMTVMVGREE
LMGIFGA
>Mature_247_residues
MNNRLSVAMHAVEQATGLAMAYFNDRHTLDITTKSAQDLVSRADFEVEQLLRAELSKHFPDDTILGEEMGGEFITDGWVI
DPIDGTGNYLRGTPLWGIAVAYMSAGEPEIGVVAYPALGYTLAARTGDGLLRNGVPFVRPQPPEHLRIAGVGENTRWDAE
EMGKLHLSLRRQGWGLAGYRCATIGLAFAALGQTDGYMEKFTSLWDIAAGAVICREAGLLCTIEGEQKQGSMTVMVGREE
LMGIFGA

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=205, Percent_Identity=28.2926829268293, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI221625487, Length=205, Percent_Identity=28.2926829268293, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI7657236, Length=207, Percent_Identity=30.4347826086957, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1788882, Length=225, Percent_Identity=28, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193202570, Length=231, Percent_Identity=30.7359307359307, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193202572, Length=228, Percent_Identity=29.3859649122807, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6320493, Length=198, Percent_Identity=29.7979797979798, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21357329, Length=234, Percent_Identity=30.3418803418803, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24664926, Length=228, Percent_Identity=31.5789473684211, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24664922, Length=210, Percent_Identity=30, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24664918, Length=198, Percent_Identity=28.2828282828283, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21357957, Length=202, Percent_Identity=26.7326732673267, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357303, Length=225, Percent_Identity=28.8888888888889, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: 3.1.3.25 [C]

Molecular weight: Translated: 26783; Mature: 26783

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNRLSVAMHAVEQATGLAMAYFNDRHTLDITTKSAQDLVSRADFEVEQLLRAELSKHFP
CCCHHHHHHHHHHHHHCEEEEEECCCEEEEEECHHHHHHHHHCCHHHHHHHHHHHHHHCC
DDTILGEEMGGEFITDGWVIDPIDGTGNYLRGTPLWGIAVAYMSAGEPEIGVVAYPALGY
CCCCCCHHHCCCEEECCEEEECCCCCCCCEECCCHHHHHHHHHCCCCCCCEEEEECCCCE
TLAARTGDGLLRNGVPFVRPQPPEHLRIAGVGENTRWDAEEMGKLHLSLRRQGWGLAGYR
EEEECCCCCHHHCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHH
CATIGLAFAALGQTDGYMEKFTSLWDIAAGAVICREAGLLCTIEGEQKQGSMTVMVGREE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECHHH
LMGIFGA
HHHHCCC
>Mature Secondary Structure
MNNRLSVAMHAVEQATGLAMAYFNDRHTLDITTKSAQDLVSRADFEVEQLLRAELSKHFP
CCCHHHHHHHHHHHHHCEEEEEECCCEEEEEECHHHHHHHHHCCHHHHHHHHHHHHHHCC
DDTILGEEMGGEFITDGWVIDPIDGTGNYLRGTPLWGIAVAYMSAGEPEIGVVAYPALGY
CCCCCCHHHCCCEEECCEEEECCCCCCCCEECCCHHHHHHHHHCCCCCCCEEEEECCCCE
TLAARTGDGLLRNGVPFVRPQPPEHLRIAGVGENTRWDAEEMGKLHLSLRRQGWGLAGYR
EEEECCCCCHHHCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCHH
CATIGLAFAALGQTDGYMEKFTSLWDIAAGAVICREAGLLCTIEGEQKQGSMTVMVGREE
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECHHH
LMGIFGA
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; 1D-myo-Inositol 1-phosphate [C]

Specific reaction: H2O + 1D-myo-Inositol 1-phosphate --> myo-Inositol + Phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]