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The map label for this gene is rbsK [H]

Identifier: 66047714

GI number: 66047714

Start: 5348764

End: 5349690

Strand: Direct

Name: rbsK [H]

Synonym: Psyr_4487

Alternate gene names: 66047714

Gene position: 5348764-5349690 (Clockwise)

Preceding gene: 66047712

Following gene: 66047715

Centisome position: 87.78

GC content: 64.94

Gene sequence:

>927_bases
ATGAGCAAGATTGCAGTCATCGGCAGCAACATGGTCGACCTGATCACTTACATCGAACGCATGCCCGCCCAGGGCGAAAC
GCTCGAGGCACCGCGTTTTGCCATGGGGTGCGGCGGCAAGGGCGCCAATCAGGCCGCCGCCGCGGCGCTGCTGGGCGCCG
ACGTGCTGATGCTCAGCAAGGTCGGCGACGATGCGTTCGCCGATACCACCCTGGCCAATTTTCAGCGACTGGGCATTGAT
ACGCGCTTCGTCGAACGGGTACCGGGCGTGTCGAGCGGCGTGGCACCGATCTTCGTCCAGGAGAACTCCCATAACAGCAT
CCTTATCGTCAAAGGCGCCAATGCCCACCTGAGCCCGGCCGATATCGACCGCGCCGAGGCGCAACTGCGCGATTGCGCTT
TGATTGTGCTGCAACTGGAAGTCGAGCTGGCGACCGTCTACCACGCCATCGCCTTCGCTCACCGGCACGCAATCCCGGTG
CTGCTCAATCCGGCCCCAGCCTTGGCCGGCCTGAGCCGCGAGCACCTCGCGCAGCTGGACTTCCTGATCCCCAACGAGAG
CGAGCTGGCCCTGATCAGCGGCCAGCCGGTGACGTGCGCCGAGGAAGCGGCTCAGGCTGCACGCCAATTGGTCGCGCTGG
GCGTACGCCACGTCATCGTCACCCTCGGCGAACAAGGGGCGCTGTACGTCGGCGCCGAAGGCGAGTGGCAGGTGCCAGGG
GTCAAGGTTCAGGCGCGTGACACCACCGGTGCCGGTGACGCCTTCATTGGCTGCTTCGCCCGGCACTGGAGCCAGGACGG
AAATATTCGCCAAGCCATGCACCAGGCGGTGGCCTACTCCGCCTGCTCGGTCACCGGCCTCGGCACGCAATCTTCTTACC
CCGATGCGTCCACGTTTGCACGATTCCTCGATGCATCGGCCAACTGA

Upstream 100 bases:

>100_bases
AGCAAAAAATAAAGATTGAATCCTCACAAAAAATGTTATTTAAATAACACAAATAAAAGCCGTCGAGGCTTCCATCGGCG
CTGGTGAGGTCAACATAACA

Downstream 100 bases:

>100_bases
CACTCACCAGCATCTCGCGGAGAACAATAATGAATAAGCCTGCGCTGCAACAAACTCCGGACGGGTTCTACCTGAACCGC
ACGCCGTGGTTCGCCTTTCT

Product: carbohydrate kinase, PfkB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSKIAVIGSNMVDLITYIERMPAQGETLEAPRFAMGCGGKGANQAAAAALLGADVLMLSKVGDDAFADTTLANFQRLGID
TRFVERVPGVSSGVAPIFVQENSHNSILIVKGANAHLSPADIDRAEAQLRDCALIVLQLEVELATVYHAIAFAHRHAIPV
LLNPAPALAGLSREHLAQLDFLIPNESELALISGQPVTCAEEAAQAARQLVALGVRHVIVTLGEQGALYVGAEGEWQVPG
VKVQARDTTGAGDAFIGCFARHWSQDGNIRQAMHQAVAYSACSVTGLGTQSSYPDASTFARFLDASAN

Sequences:

>Translated_308_residues
MSKIAVIGSNMVDLITYIERMPAQGETLEAPRFAMGCGGKGANQAAAAALLGADVLMLSKVGDDAFADTTLANFQRLGID
TRFVERVPGVSSGVAPIFVQENSHNSILIVKGANAHLSPADIDRAEAQLRDCALIVLQLEVELATVYHAIAFAHRHAIPV
LLNPAPALAGLSREHLAQLDFLIPNESELALISGQPVTCAEEAAQAARQLVALGVRHVIVTLGEQGALYVGAEGEWQVPG
VKVQARDTTGAGDAFIGCFARHWSQDGNIRQAMHQAVAYSACSVTGLGTQSSYPDASTFARFLDASAN
>Mature_307_residues
SKIAVIGSNMVDLITYIERMPAQGETLEAPRFAMGCGGKGANQAAAAALLGADVLMLSKVGDDAFADTTLANFQRLGIDT
RFVERVPGVSSGVAPIFVQENSHNSILIVKGANAHLSPADIDRAEAQLRDCALIVLQLEVELATVYHAIAFAHRHAIPVL
LNPAPALAGLSREHLAQLDFLIPNESELALISGQPVTCAEEAAQAARQLVALGVRHVIVTLGEQGALYVGAEGEWQVPGV
KVQARDTTGAGDAFIGCFARHWSQDGNIRQAMHQAVAYSACSVTGLGTQSSYPDASTFARFLDASAN

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=291, Percent_Identity=38.1443298969072, Blast_Score=184, Evalue=1e-46,
Organism=Escherichia coli, GI1790193, Length=302, Percent_Identity=37.7483443708609, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI87082343, Length=309, Percent_Identity=28.8025889967638, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788491, Length=272, Percent_Identity=25.3676470588235, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788484, Length=257, Percent_Identity=25.6809338521401, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=293, Percent_Identity=35.8361774744027, Blast_Score=180, Evalue=8e-46,
Organism=Saccharomyces cerevisiae, GI6319884, Length=323, Percent_Identity=28.1733746130031, Blast_Score=99, Evalue=6e-22,
Organism=Drosophila melanogaster, GI20128807, Length=306, Percent_Identity=36.9281045751634, Blast_Score=161, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24583886, Length=310, Percent_Identity=31.2903225806452, Blast_Score=139, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32410; Mature: 32279

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKIAVIGSNMVDLITYIERMPAQGETLEAPRFAMGCGGKGANQAAAAALLGADVLMLSK
CCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHH
VGDDAFADTTLANFQRLGIDTRFVERVPGVSSGVAPIFVQENSHNSILIVKGANAHLSPA
CCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCHH
DIDRAEAQLRDCALIVLQLEVELATVYHAIAFAHRHAIPVLLNPAPALAGLSREHLAQLD
HHHHHHHHHHHHEEEEEEEHHHHHHHHHHHHHHHHCCCEEEECCCHHHHCCCHHHHHHHH
FLIPNESELALISGQPVTCAEEAAQAARQLVALGVRHVIVTLGEQGALYVGAEGEWQVPG
EECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEECCCCCEECCC
VKVQARDTTGAGDAFIGCFARHWSQDGNIRQAMHQAVAYSACSVTGLGTQSSYPDASTFA
EEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHH
RFLDASAN
HHHHCCCC
>Mature Secondary Structure 
SKIAVIGSNMVDLITYIERMPAQGETLEAPRFAMGCGGKGANQAAAAALLGADVLMLSK
CCEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHH
VGDDAFADTTLANFQRLGIDTRFVERVPGVSSGVAPIFVQENSHNSILIVKGANAHLSPA
CCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCEEEEEECCCCEEEEEECCCCCCCHH
DIDRAEAQLRDCALIVLQLEVELATVYHAIAFAHRHAIPVLLNPAPALAGLSREHLAQLD
HHHHHHHHHHHHEEEEEEEHHHHHHHHHHHHHHHHCCCEEEECCCHHHHCCCHHHHHHHH
FLIPNESELALISGQPVTCAEEAAQAARQLVALGVRHVIVTLGEQGALYVGAEGEWQVPG
EECCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEECCCCCEECCC
VKVQARDTTGAGDAFIGCFARHWSQDGNIRQAMHQAVAYSACSVTGLGTQSSYPDASTFA
EEEEECCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHH
RFLDASAN
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]