Click here to switch to the map view.

The map label for this gene is fucP [H]

Identifier: 66047715

GI number: 66047715

Start: 5349720

End: 5351051

Strand: Direct

Name: fucP [H]

Synonym: Psyr_4488

Alternate gene names: 66047715

Gene position: 5349720-5351051 (Clockwise)

Preceding gene: 66047714

Following gene: 66047716

Centisome position: 87.79

GC content: 60.96

Gene sequence:

>1332_bases
ATGAATAAGCCTGCGCTGCAACAAACTCCGGACGGGTTCTACCTGAACCGCACGCCGTGGTTCGCCTTTCTCCTGCTCTG
CAGCATATTTGCCCTGTGGGCGGCGGCCGCGAGCATGAACGACGTGCTGATCGCGCACTTCAAGAAGGCCTTCCTGCTCA
GTGACTTCCAGACCGCTTTCGTGCAGTCGGCGTTTTACCTGGGTTACTTCTTCGTCGCCATTCCGGCGGCATTGGTGGTG
CGCCGCTTCAGCTACAAGACCACTATCCTCATCGGCCTGATGCTGTACCTGTTCGGCTGCGCCCTGTTCTTTCCGGCGGC
GTCGACTGCCAAGTACGGCATGTTCCTGATGGCGCTGTTCGTCATCGCCGCCGGCCTGTCGTTTCTCGAGACCGCGTGCA
ACACCTACTCGACACTGATGGGGCCGCGGGAAACCGGCACGCGGCGCCTGAACATCTCGCAGACCTTCCACCCATTCGGC
GCCATGACCGGGGTGTACGTCGGCAGCTTCGTGATGTTCAAGGACACAGACGCCACGCGCGAACAGTTGGCCCAGATGAG
CGCCAGCGAGGCGGCGGCGCAGCAGCTGCAAATGATCCAGTCGACCCTGCTGCCGTACAAATGGATGATCGCGGTACTCA
TATTGATGTTCATCCTGATAGCCATCACCCGCTTCCCCGCGTGCAAGGGCAACGGCACCGTCAGCGAATCGCGTTCGAGC
ATCGGCCAGAGCCTCGGCCGCCTGCGGCGCAATCCGCGCTTTTGCTTCGGTGTGCTGGCGCAGTTCCTCTACGTCGGCGC
GCAGGTCGGGGTATGGAGTTTCACTATTCGCCTGGCCATGCAAATGGGCGGCATGAACGAGCGCAGTGCCTCGTGGTTTC
TGCTGACCACCTTTGCCGCCTATTTTATCGGCAAGATGATCGCCAATCTGCTGATGCGCAAAATGCACCCGGCCAAAGTC
CTCGCGGTGTATGGCGTGCTGTGCATCGTGCTGCTGGCCTACACTATCCTGGTGCCGAATATCACTGCGGTGTATGCGGC
CGTAGGGGTCAGTGTGTTTCTCGGGCCTTGCTGGCCGACCATCTATGGTCTGACCATTGACGGGCTCGGCGAGGACACCG
GTGTCGGCGGCTCGTTGCTGGTGATGAGCATCGTTGGCGGTGGCGTGATGCCGATCTTCCAGGGCCTGCTCAGCGACGCC
AATGGCGGCAACATGCAGATTGCCTACAGCGTGCCGCTGCTGTGTTTCGTGGCCATCGTTATGTACGCAGTGTACTGCAT
GCGTCAGCCGCAACCGGTGCTGGGTGGTTCGGCCACGGCGGTAGCGCAATGA

Upstream 100 bases:

>100_bases
GCCTCGGCACGCAATCTTCTTACCCCGATGCGTCCACGTTTGCACGATTCCTCGATGCATCGGCCAACTGACACTCACCA
GCATCTCGCGGAGAACAATA

Downstream 100 bases:

>100_bases
GTAGCGAAGCGTGGCGCCTGCCGCTCTACCCACAGCTCTGGGACCAGGCCAGCCGGCTGCTGCTCGAATCAGCCAGTTTC
AGCGTGCGTGCCTGGACCTA

Product: L-fucose permease

Products: Proton [Cytoplasm]; L-fucose [Cytoplasm] [C]

Alternate protein names: 6-deoxy-L-galactose permease; L-fucose permease [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MNKPALQQTPDGFYLNRTPWFAFLLLCSIFALWAAAASMNDVLIAHFKKAFLLSDFQTAFVQSAFYLGYFFVAIPAALVV
RRFSYKTTILIGLMLYLFGCALFFPAASTAKYGMFLMALFVIAAGLSFLETACNTYSTLMGPRETGTRRLNISQTFHPFG
AMTGVYVGSFVMFKDTDATREQLAQMSASEAAAQQLQMIQSTLLPYKWMIAVLILMFILIAITRFPACKGNGTVSESRSS
IGQSLGRLRRNPRFCFGVLAQFLYVGAQVGVWSFTIRLAMQMGGMNERSASWFLLTTFAAYFIGKMIANLLMRKMHPAKV
LAVYGVLCIVLLAYTILVPNITAVYAAVGVSVFLGPCWPTIYGLTIDGLGEDTGVGGSLLVMSIVGGGVMPIFQGLLSDA
NGGNMQIAYSVPLLCFVAIVMYAVYCMRQPQPVLGGSATAVAQ

Sequences:

>Translated_443_residues
MNKPALQQTPDGFYLNRTPWFAFLLLCSIFALWAAAASMNDVLIAHFKKAFLLSDFQTAFVQSAFYLGYFFVAIPAALVV
RRFSYKTTILIGLMLYLFGCALFFPAASTAKYGMFLMALFVIAAGLSFLETACNTYSTLMGPRETGTRRLNISQTFHPFG
AMTGVYVGSFVMFKDTDATREQLAQMSASEAAAQQLQMIQSTLLPYKWMIAVLILMFILIAITRFPACKGNGTVSESRSS
IGQSLGRLRRNPRFCFGVLAQFLYVGAQVGVWSFTIRLAMQMGGMNERSASWFLLTTFAAYFIGKMIANLLMRKMHPAKV
LAVYGVLCIVLLAYTILVPNITAVYAAVGVSVFLGPCWPTIYGLTIDGLGEDTGVGGSLLVMSIVGGGVMPIFQGLLSDA
NGGNMQIAYSVPLLCFVAIVMYAVYCMRQPQPVLGGSATAVAQ
>Mature_443_residues
MNKPALQQTPDGFYLNRTPWFAFLLLCSIFALWAAAASMNDVLIAHFKKAFLLSDFQTAFVQSAFYLGYFFVAIPAALVV
RRFSYKTTILIGLMLYLFGCALFFPAASTAKYGMFLMALFVIAAGLSFLETACNTYSTLMGPRETGTRRLNISQTFHPFG
AMTGVYVGSFVMFKDTDATREQLAQMSASEAAAQQLQMIQSTLLPYKWMIAVLILMFILIAITRFPACKGNGTVSESRSS
IGQSLGRLRRNPRFCFGVLAQFLYVGAQVGVWSFTIRLAMQMGGMNERSASWFLLTTFAAYFIGKMIANLLMRKMHPAKV
LAVYGVLCIVLLAYTILVPNITAVYAAVGVSVFLGPCWPTIYGLTIDGLGEDTGVGGSLLVMSIVGGGVMPIFQGLLSDA
NGGNMQIAYSVPLLCFVAIVMYAVYCMRQPQPVLGGSATAVAQ

Specific function: Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-

COG id: COG0738

COG function: function code G; Fucose permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family [H]

Homologues:

Organism=Escherichia coli, GI1789166, Length=412, Percent_Identity=39.3203883495146, Blast_Score=298, Evalue=4e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005275
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48259; Mature: 48259

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPALQQTPDGFYLNRTPWFAFLLLCSIFALWAAAASMNDVLIAHFKKAFLLSDFQTAF
CCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
VQSAFYLGYFFVAIPAALVVRRFSYKTTILIGLMLYLFGCALFFPAASTAKYGMFLMALF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VIAAGLSFLETACNTYSTLMGPRETGTRRLNISQTFHPFGAMTGVYVGSFVMFKDTDATR
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHCHHHHHHHHHHHHEEEEECCHHHH
EQLAQMSASEAAAQQLQMIQSTLLPYKWMIAVLILMFILIAITRFPACKGNGTVSESRSS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
IGQSLGRLRRNPRFCFGVLAQFLYVGAQVGVWSFTIRLAMQMGGMNERSASWFLLTTFAA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
YFIGKMIANLLMRKMHPAKVLAVYGVLCIVLLAYTILVPNITAVYAAVGVSVFLGPCWPT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHH
IYGLTIDGLGEDTGVGGSLLVMSIVGGGVMPIFQGLLSDANGGNMQIAYSVPLLCFVAIV
HHCEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHH
MYAVYCMRQPQPVLGGSATAVAQ
HHHHHHHCCCCCCCCCCCHHCCC
>Mature Secondary Structure
MNKPALQQTPDGFYLNRTPWFAFLLLCSIFALWAAAASMNDVLIAHFKKAFLLSDFQTAF
CCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
VQSAFYLGYFFVAIPAALVVRRFSYKTTILIGLMLYLFGCALFFPAASTAKYGMFLMALF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VIAAGLSFLETACNTYSTLMGPRETGTRRLNISQTFHPFGAMTGVYVGSFVMFKDTDATR
HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCHHHCHHHHHHHHHHHHEEEEECCHHHH
EQLAQMSASEAAAQQLQMIQSTLLPYKWMIAVLILMFILIAITRFPACKGNGTVSESRSS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
IGQSLGRLRRNPRFCFGVLAQFLYVGAQVGVWSFTIRLAMQMGGMNERSASWFLLTTFAA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
YFIGKMIANLLMRKMHPAKVLAVYGVLCIVLLAYTILVPNITAVYAAVGVSVFLGPCWPT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHH
IYGLTIDGLGEDTGVGGSLLVMSIVGGGVMPIFQGLLSDANGGNMQIAYSVPLLCFVAIV
HHCEEECCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHH
MYAVYCMRQPQPVLGGSATAVAQ
HHHHHHHCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-fucose [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-fucose [Periplasm] = Proton [Cytoplasm] + L-fucose [Cytoplasm] [C]

General reaction: Permease [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2664711; 9278503; 2553671; 8052131; 2829831; 7783647 [H]