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The map label for this gene is cobK [H]

Identifier: 66047647

GI number: 66047647

Start: 5284407

End: 5285147

Strand: Direct

Name: cobK [H]

Synonym: Psyr_4420

Alternate gene names: 66047647

Gene position: 5284407-5285147 (Clockwise)

Preceding gene: 66047646

Following gene: 66047649

Centisome position: 86.72

GC content: 65.32

Gene sequence:

>741_bases
ATGAAACGCATCCTGCTGCTGGGCGGCATTACCGAGGCGCTGGCCATTGCGCGAAGGCTCGGGCCTGAGCACATCTACAG
CCTGGCGGGTGTGGGCCGGGTGCCATCGGATCTGGCCTGCCAATTGAAGGTCGGCGGTTATGGCGGCGCCGAGGGCATGG
CGCAGTACATGGGCGAACAGGGCGTCGACCTGCTGCTGGACGCAACCCATCCCTACGCCGCGCAGATCAGCCACAACGCA
GCGCGTGCGGCCAGGCTGGCGGGCATTCCCTGCTGGGCCTTGCGCCGCACCGCGTGGCAGGCAGGTCCGGGGGATGACTG
GCGTGAAGTGGCTGACTGGTCAGAACTGGCCTCTGCCTTGCTCCCCTTCAAGCGCCCGCTGTTCACGCTGGGTCGTGAGC
CCTTGCAGCACCTGAACGAAATCCCCCCGCACCAGTTCTGGACACTCCGGGCACTGGACGACTACCCCGGCAACGAACGC
TGCGAAGTGATCGGCGCACGCGGCCCCTTCATGCTGGAAGACGAACGCCAGTTGTTCGAACAGCGCCGCATCGACGTACT
GATCAGCAAAAACAGCGGCAGCAGCTCCACCGAACCCAAACTGGATGTCGCCCGCGAACGCGGCCTGCCCGTCCTGATCC
TCAAACGCCCGCAGTTGCCTGACGTCGACCGGCTGTTCTGGGGCGTGGATGAGGTGCTGGAGGCCTTGGGGCTGGAGTCA
ATGAGCCGTCAGTCCTCATGA

Upstream 100 bases:

>100_bases
GCAGCATCGTGCCTGCGAGCGTTCAGGTGGAGGTTTTCGCAATTGATCGTCAAGGCGGGCTGGTGGGTCAGGCTGGCGTT
GACTCACAGAGAGAAATCAC

Downstream 100 bases:

>100_bases
AAATTCTGAAAACACCCCGCCCCTGTGGGAGTGAGCTTGCTCACGAAGAGGCCGGGGCAGTCGCTGAAAATCTATATATC
CGTGACTCCCCCTTCGCGAG

Product: cobalt-precorrin-6x reductase

Products: NA

Alternate protein names: Precorrin-6X reductase [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKRILLLGGITEALAIARRLGPEHIYSLAGVGRVPSDLACQLKVGGYGGAEGMAQYMGEQGVDLLLDATHPYAAQISHNA
ARAARLAGIPCWALRRTAWQAGPGDDWREVADWSELASALLPFKRPLFTLGREPLQHLNEIPPHQFWTLRALDDYPGNER
CEVIGARGPFMLEDERQLFEQRRIDVLISKNSGSSSTEPKLDVARERGLPVLILKRPQLPDVDRLFWGVDEVLEALGLES
MSRQSS

Sequences:

>Translated_246_residues
MKRILLLGGITEALAIARRLGPEHIYSLAGVGRVPSDLACQLKVGGYGGAEGMAQYMGEQGVDLLLDATHPYAAQISHNA
ARAARLAGIPCWALRRTAWQAGPGDDWREVADWSELASALLPFKRPLFTLGREPLQHLNEIPPHQFWTLRALDDYPGNER
CEVIGARGPFMLEDERQLFEQRRIDVLISKNSGSSSTEPKLDVARERGLPVLILKRPQLPDVDRLFWGVDEVLEALGLES
MSRQSS
>Mature_246_residues
MKRILLLGGITEALAIARRLGPEHIYSLAGVGRVPSDLACQLKVGGYGGAEGMAQYMGEQGVDLLLDATHPYAAQISHNA
ARAARLAGIPCWALRRTAWQAGPGDDWREVADWSELASALLPFKRPLFTLGREPLQHLNEIPPHQFWTLRALDDYPGNER
CEVIGARGPFMLEDERQLFEQRRIDVLISKNSGSSSTEPKLDVARERGLPVLILKRPQLPDVDRLFWGVDEVLEALGLES
MSRQSS

Specific function: Catalyzes the reduction of the macrocycle of precorrin- 6X into precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: =1.3.1.54 [H]

Molecular weight: Translated: 27243; Mature: 27243

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILLLGGITEALAIARRLGPEHIYSLAGVGRVPSDLACQLKVGGYGGAEGMAQYMGEQ
CCEEEEECCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHCCC
GVDLLLDATHPYAAQISHNAARAARLAGIPCWALRRTAWQAGPGDDWREVADWSELASAL
CCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LPFKRPLFTLGREPLQHLNEIPPHQFWTLRALDDYPGNERCEVIGARGPFMLEDERQLFE
HHHCCHHHHHCHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEECCCCEEECHHHHHHH
QRRIDVLISKNSGSSSTEPKLDVARERGLPVLILKRPQLPDVDRLFWGVDEVLEALGLES
HCCEEEEEECCCCCCCCCCCHHHHHHCCCEEEEECCCCCCCHHHHHHCHHHHHHHHCHHH
MSRQSS
HHHCCC
>Mature Secondary Structure
MKRILLLGGITEALAIARRLGPEHIYSLAGVGRVPSDLACQLKVGGYGGAEGMAQYMGEQ
CCEEEEECCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHCCC
GVDLLLDATHPYAAQISHNAARAARLAGIPCWALRRTAWQAGPGDDWREVADWSELASAL
CCEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LPFKRPLFTLGREPLQHLNEIPPHQFWTLRALDDYPGNERCEVIGARGPFMLEDERQLFE
HHHCCHHHHHCHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEEEECCCCEEECHHHHHHH
QRRIDVLISKNSGSSSTEPKLDVARERGLPVLILKRPQLPDVDRLFWGVDEVLEALGLES
HCCEEEEEECCCCCCCCCCCHHHHHHCCCEEEEECCCCCCCHHHHHHCHHHHHHHHCHHH
MSRQSS
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2211521; 1732193 [H]