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The map label for this gene is mltB [H]

Identifier: 66047584

GI number: 66047584

Start: 5210314

End: 5211651

Strand: Direct

Name: mltB [H]

Synonym: Psyr_4357

Alternate gene names: 66047584

Gene position: 5210314-5211651 (Clockwise)

Preceding gene: 66047583

Following gene: 66047597

Centisome position: 85.5

GC content: 61.88

Gene sequence:

>1338_bases
ATGCCTTCTCGTTTTACCCATCGCCCGCAGCTGCGCCAACTCATCGCTGCCTCCAGTCTTGTTGCCCTGGTAGCCTGCGC
AGAAAAACCCACTGCAGCCGATGCCACACCTCTTCAATCCAGCAAGGTGCAGACAAACGCTCCTGCCGTAGCGCCTACGC
CAGCACTGGTCGTTGATGACAACCTCACGATTCAGCCCGCCGTCAGCTTCAGCGAATGGCAGGCCGGCTTTCGTGCCCAG
GCGTTGAAGGCAGGCATTCGCGCGGACGTATTCGATCTGGCATTTGCCGGCGTCACCCCCGACATGAGCGTAGTCAAGGC
CGACCGCAGTCAGCCTGAATTCAGCCGCCCGGTCTGGGAATACCTTGACGGTGCCATCTCTGCCGCACGCGTACGCAAGG
GTCAGGCGCTGCTGTCGCAGTATGCCGACGACCTGCAGAAGATCGAGCAGCAGTACGGCGTCGATCGTCAGACGCTGGTC
GCGGTGTGGGGCATGGAAAGTAATTTCGGGTCGTTACAGGGTACGCAATCCGTCATTCGCTCACTCGCGACACTGGCCTA
TGAAGGTCGCCGTCCCGGCTTTGCACAAAGCCAGTTGCTCGCCGCGCTGGAAATCATCCAGCATGGCGACATAACCCCGG
ACAAAATGCTGGGTTCGTGGGCCGGTGCGATGGGCCAGACGCAGTTCATCCCTACCACCTACAACACCCACGCCGTGGAT
TTTGACGGCGATGGCCGACGTGATATCTGGAACACCCCGGCCGATGCCCTGGCCTCCACTGCGCACTACCTGCAAAGCTC
CGGCTGGCAGCGTGGTCAGCCCTGGGGCTTTGAAGTGGTGCTCGGCTCGGGGTTCGATTACTCGCTGGCCGATTCGACAA
CCCGCAAGAGTCTCGTTGAATGGCAGCAACTGGGTCTGAAACAGCCCGACGGCTCAGCCATTCCGGTCGCCGCCAGCCAG
CAGCAAGCCGCCTTGCTGTTGCCAGCCGGTTATCGCGGGCCAGCCTTTCTGGTGCTGGACAACTTCCGCGCGATTCTCAA
GTACAACAACTCGACCTCCTACGCGTTGGCGATCAGCCTGCTCTCCGATCGCTTCAAGGGCGCGGGCTATGTCGTGGGCA
GCTGGCCGCGCGGAGACCTGCCGCTGAGCCGCTCAGAGCGCATTGAGCTGCAAACCCTGCTCTCGGCACGCCAGTACGAC
GCAGGCGCGCCAGACGGCATTATCGGCGCCAATACACGCAAGGCCATCCGCAGTGCGCAGCAATCGCTCGGCTGGCCAGC
CGATGGTTACCCGACGCATGAATTGCTGGAGAACCTGCGCAAGCCTGTCGGGCAGTAA

Upstream 100 bases:

>100_bases
GCTTTATGGCAGCCTGATATCGAGCAACATTTCCGGGGCGCTTTCAACCGCTTAGCCGTGTTATGGTCTGCACCTAACGG
TAATACCCTTGGACTCAAGC

Downstream 100 bases:

>100_bases
TCGGGAGGACGCAGAGCGTCCAGAACGGCATGCCAACGCGGAGCATTGGCACGATAGCGTTCTTACGGACGCCTATCGCT
CCTCACGCTCCAGCGTGGGA

Product: hypothetical protein

Products: Muramic Acid Residue [C]

Alternate protein names: 35 kDa soluble lytic transglycosylase; Murein hydrolase B; Slt35 [H]

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MPSRFTHRPQLRQLIAASSLVALVACAEKPTAADATPLQSSKVQTNAPAVAPTPALVVDDNLTIQPAVSFSEWQAGFRAQ
ALKAGIRADVFDLAFAGVTPDMSVVKADRSQPEFSRPVWEYLDGAISAARVRKGQALLSQYADDLQKIEQQYGVDRQTLV
AVWGMESNFGSLQGTQSVIRSLATLAYEGRRPGFAQSQLLAALEIIQHGDITPDKMLGSWAGAMGQTQFIPTTYNTHAVD
FDGDGRRDIWNTPADALASTAHYLQSSGWQRGQPWGFEVVLGSGFDYSLADSTTRKSLVEWQQLGLKQPDGSAIPVAASQ
QQAALLLPAGYRGPAFLVLDNFRAILKYNNSTSYALAISLLSDRFKGAGYVVGSWPRGDLPLSRSERIELQTLLSARQYD
AGAPDGIIGANTRKAIRSAQQSLGWPADGYPTHELLENLRKPVGQ

Sequences:

>Translated_445_residues
MPSRFTHRPQLRQLIAASSLVALVACAEKPTAADATPLQSSKVQTNAPAVAPTPALVVDDNLTIQPAVSFSEWQAGFRAQ
ALKAGIRADVFDLAFAGVTPDMSVVKADRSQPEFSRPVWEYLDGAISAARVRKGQALLSQYADDLQKIEQQYGVDRQTLV
AVWGMESNFGSLQGTQSVIRSLATLAYEGRRPGFAQSQLLAALEIIQHGDITPDKMLGSWAGAMGQTQFIPTTYNTHAVD
FDGDGRRDIWNTPADALASTAHYLQSSGWQRGQPWGFEVVLGSGFDYSLADSTTRKSLVEWQQLGLKQPDGSAIPVAASQ
QQAALLLPAGYRGPAFLVLDNFRAILKYNNSTSYALAISLLSDRFKGAGYVVGSWPRGDLPLSRSERIELQTLLSARQYD
AGAPDGIIGANTRKAIRSAQQSLGWPADGYPTHELLENLRKPVGQ
>Mature_444_residues
PSRFTHRPQLRQLIAASSLVALVACAEKPTAADATPLQSSKVQTNAPAVAPTPALVVDDNLTIQPAVSFSEWQAGFRAQA
LKAGIRADVFDLAFAGVTPDMSVVKADRSQPEFSRPVWEYLDGAISAARVRKGQALLSQYADDLQKIEQQYGVDRQTLVA
VWGMESNFGSLQGTQSVIRSLATLAYEGRRPGFAQSQLLAALEIIQHGDITPDKMLGSWAGAMGQTQFIPTTYNTHAVDF
DGDGRRDIWNTPADALASTAHYLQSSGWQRGQPWGFEVVLGSGFDYSLADSTTRKSLVEWQQLGLKQPDGSAIPVAASQQ
QAALLLPAGYRGPAFLVLDNFRAILKYNNSTSYALAISLLSDRFKGAGYVVGSWPRGDLPLSRSERIELQTLLSARQYDA
GAPDGIIGANTRKAIRSAQQSLGWPADGYPTHELLENLRKPVGQ

Specific function: Murein-degrading enzyme. Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N- acetylglucosamine residues in peptidoglycan. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG2951

COG function: function code M; Membrane-bound lytic murein transglycosylase B

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789053, Length=244, Percent_Identity=33.6065573770492, Blast_Score=118, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011757 [H]

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 48147; Mature: 48015

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSRFTHRPQLRQLIAASSLVALVACAEKPTAADATPLQSSKVQTNAPAVAPTPALVVDD
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECC
NLTIQPAVSFSEWQAGFRAQALKAGIRADVFDLAFAGVTPDMSVVKADRSQPEFSRPVWE
CEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCHHHH
YLDGAISAARVRKGQALLSQYADDLQKIEQQYGVDRQTLVAVWGMESNFGSLQGTQSVIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCHHHHHHHH
SLATLAYEGRRPGFAQSQLLAALEIIQHGDITPDKMLGSWAGAMGQTQFIPTTYNTHAVD
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEECCCCCCEEEE
FDGDGRRDIWNTPADALASTAHYLQSSGWQRGQPWGFEVVLGSGFDYSLADSTTRKSLVE
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHH
WQQLGLKQPDGSAIPVAASQQQAALLLPAGYRGPAFLVLDNFRAILKYNNSTSYALAISL
HHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCEEEEEECCCCCHHHHHHH
LSDRFKGAGYVVGSWPRGDLPLSRSERIELQTLLSARQYDAGAPDGIIGANTRKAIRSAQ
HHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
QSLGWPADGYPTHELLENLRKPVGQ
HHCCCCCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSRFTHRPQLRQLIAASSLVALVACAEKPTAADATPLQSSKVQTNAPAVAPTPALVVDD
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECC
NLTIQPAVSFSEWQAGFRAQALKAGIRADVFDLAFAGVTPDMSVVKADRSQPEFSRPVWE
CEEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCHHHH
YLDGAISAARVRKGQALLSQYADDLQKIEQQYGVDRQTLVAVWGMESNFGSLQGTQSVIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCHHHHHHHH
SLATLAYEGRRPGFAQSQLLAALEIIQHGDITPDKMLGSWAGAMGQTQFIPTTYNTHAVD
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEECCCCCCEEEE
FDGDGRRDIWNTPADALASTAHYLQSSGWQRGQPWGFEVVLGSGFDYSLADSTTRKSLVE
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHH
WQQLGLKQPDGSAIPVAASQQQAALLLPAGYRGPAFLVLDNFRAILKYNNSTSYALAISL
HHHCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEECCCEEEEEECCCCCHHHHHHH
LSDRFKGAGYVVGSWPRGDLPLSRSERIELQTLLSARQYDAGAPDGIIGANTRKAIRSAQ
HHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
QSLGWPADGYPTHELLENLRKPVGQ
HHCCCCCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

General reaction: Cleavage Bond [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7476170; 7789526; 9205837; 9278503; 3553176; 9761817; 10570954; 10545329; 10684641 [H]