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The map label for this gene is corC [H]

Identifier: 66047575

GI number: 66047575

Start: 5201324

End: 5202166

Strand: Direct

Name: corC [H]

Synonym: Psyr_4348

Alternate gene names: 66047575

Gene position: 5201324-5202166 (Clockwise)

Preceding gene: 66047574

Following gene: 66047576

Centisome position: 85.36

GC content: 58.84

Gene sequence:

>843_bases
ATGAGCGAAGACCGATCGAGCAACGGGCAAAAGTCATGGTTGGGTAAACTGACCCAGGCCTTTGTCCATGAGCCGAAAAA
CCGCCAGGAGCTGCTTGAGCTGCTGCGCGAAGCCCACCAGAACAAACTGCTGGACAGCGAAGCGCTGGCCATCGTCGAGG
GCGCCATTCAAGTGGCTGACCTGCAAGTGCGCGACATCATGGTGCCGCGCTCGCAGATGATCAGCATCAAGGCGACCCAG
ACACCCCGTGAATTTCTGCCGGCGGTCATCGATGCTGCGCACTCGCGCTATCCGGTGATCGGCGAGAGCCACGATGACGT
GCTCGGTGTGCTGCTGGCCAAGGATCTGCTGCCGCTGATCCTCAAGGCCGACGGCGACAGTGATGACGTCAAGAAGCTGC
TGCGTCCGGCCACCTTCGTGCCCGAATCCAAGCGTCTCAACGTGCTGCTGCGCGAGTTTCGCGCCAACCACAACCACATG
GCCATCGTCATTGACGAATACGGCGGCGTGGCAGGTCTGGTGACCATCGAAGACGTGCTGGAACAGATCGTCGGCGATAT
CGAAGACGAGCATGACGTCGAGGAAGACAGCTACATCAAACCGCTGCCCAGCGGCGACTTCCTGGTCAAGGCCCTTACCC
CGGTCGAGAATTTCAACGAATTCTTCGACAGCACGTTCTCGGACGACGAGTTCGATACTGTGGGCGGTCTGGTGATGAAT
GCCTTCGGCCATCTGCCCAAGCGCAACGAAATCACTGAAATCGGTGCTTATCGTTTCCGCATCCTGAGCGCTGACAGCCG
TCGCATTCATTTGCTGCGCGTGACGCCCATTTCACGTCCGTAA

Upstream 100 bases:

>100_bases
CGTTGCTTGAGGAGCTGGGCTATCCCGATCCTTACGCCGACGACGAAAGTGCCGACCCTCCCCATTCAGACACACCAAGC
AAGGACCACGAGTAAGGGCT

Downstream 100 bases:

>100_bases
ACACTTGATGCTGCTTTAAGGAATCTACATGCGCTGGATAACCCGCCCCGGCTGGCCCGGTAACCTGCTGGCCCTGGCGG
CTGGCGGGCTCACGACTCTG

Product: CBS:transporter-associated region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MSEDRSSNGQKSWLGKLTQAFVHEPKNRQELLELLREAHQNKLLDSEALAIVEGAIQVADLQVRDIMVPRSQMISIKATQ
TPREFLPAVIDAAHSRYPVIGESHDDVLGVLLAKDLLPLILKADGDSDDVKKLLRPATFVPESKRLNVLLREFRANHNHM
AIVIDEYGGVAGLVTIEDVLEQIVGDIEDEHDVEEDSYIKPLPSGDFLVKALTPVENFNEFFDSTFSDDEFDTVGGLVMN
AFGHLPKRNEITEIGAYRFRILSADSRRIHLLRVTPISRP

Sequences:

>Translated_280_residues
MSEDRSSNGQKSWLGKLTQAFVHEPKNRQELLELLREAHQNKLLDSEALAIVEGAIQVADLQVRDIMVPRSQMISIKATQ
TPREFLPAVIDAAHSRYPVIGESHDDVLGVLLAKDLLPLILKADGDSDDVKKLLRPATFVPESKRLNVLLREFRANHNHM
AIVIDEYGGVAGLVTIEDVLEQIVGDIEDEHDVEEDSYIKPLPSGDFLVKALTPVENFNEFFDSTFSDDEFDTVGGLVMN
AFGHLPKRNEITEIGAYRFRILSADSRRIHLLRVTPISRP
>Mature_279_residues
SEDRSSNGQKSWLGKLTQAFVHEPKNRQELLELLREAHQNKLLDSEALAIVEGAIQVADLQVRDIMVPRSQMISIKATQT
PREFLPAVIDAAHSRYPVIGESHDDVLGVLLAKDLLPLILKADGDSDDVKKLLRPATFVPESKRLNVLLREFRANHNHMA
IVIDEYGGVAGLVTIEDVLEQIVGDIEDEHDVEEDSYIKPLPSGDFLVKALTPVENFNEFFDSTFSDDEFDTVGGLVMNA
FGHLPKRNEITEIGAYRFRILSADSRRIHLLRVTPISRP

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=179, Percent_Identity=31.8435754189944, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI40068055, Length=192, Percent_Identity=30.2083333333333, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI40068053, Length=192, Percent_Identity=30.2083333333333, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI94681046, Length=188, Percent_Identity=29.2553191489362, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1786879, Length=268, Percent_Identity=52.6119402985075, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI145693175, Length=220, Percent_Identity=29.0909090909091, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788119, Length=228, Percent_Identity=30.2631578947368, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082033, Length=259, Percent_Identity=25.0965250965251, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790664, Length=233, Percent_Identity=25.3218884120172, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 31397; Mature: 31266

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDRSSNGQKSWLGKLTQAFVHEPKNRQELLELLREAHQNKLLDSEALAIVEGAIQVAD
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
LQVRDIMVPRSQMISIKATQTPREFLPAVIDAAHSRYPVIGESHDDVLGVLLAKDLLPLI
CHHHHEECCHHHEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHE
LKADGDSDDVKKLLRPATFVPESKRLNVLLREFRANHNHMAIVIDEYGGVAGLVTIEDVL
EECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEEEHHHHHHH
EQIVGDIEDEHDVEEDSYIKPLPSGDFLVKALTPVENFNEFFDSTFSDDEFDTVGGLVMN
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHH
AFGHLPKRNEITEIGAYRFRILSADSRRIHLLRVTPISRP
HHHCCCCCCCHHHHHHEEEEEEECCCCEEEEEEECCCCCC
>Mature Secondary Structure 
SEDRSSNGQKSWLGKLTQAFVHEPKNRQELLELLREAHQNKLLDSEALAIVEGAIQVAD
CCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
LQVRDIMVPRSQMISIKATQTPREFLPAVIDAAHSRYPVIGESHDDVLGVLLAKDLLPLI
CHHHHEECCHHHEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHE
LKADGDSDDVKKLLRPATFVPESKRLNVLLREFRANHNHMAIVIDEYGGVAGLVTIEDVL
EECCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCEEEEHHHHHHH
EQIVGDIEDEHDVEEDSYIKPLPSGDFLVKALTPVENFNEFFDSTFSDDEFDTVGGLVMN
HHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHH
AFGHLPKRNEITEIGAYRFRILSADSRRIHLLRVTPISRP
HHHCCCCCCCHHHHHHEEEEEEECCCCEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]