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The map label for this gene is aidB [H]

Identifier: 66047565

GI number: 66047565

Start: 5189819

End: 5191468

Strand: Reverse

Name: aidB [H]

Synonym: Psyr_4338

Alternate gene names: 66047565

Gene position: 5191468-5189819 (Counterclockwise)

Preceding gene: 66047566

Following gene: 66047564

Centisome position: 85.19

GC content: 64.42

Gene sequence:

>1650_bases
ATGAACCTGAATCAATTCGCCGAAACCCACGAAGTCACCAATCAACCGCCGCCGCTGGACGGGGCAAACCTTTACCGTAT
CGACGTGCCGCTTCAGGAGTGGAGCAGCAGATTCGGTGCAGGCTGGGCGCAGCCGCGTATCGACGCCTATGGTGCGCTGG
CAGGAGGTCCGCTGATGGCGGCGGGCTTCCTGGCCAACCAGCACAGGCCCGAGTTTGCCAGCCATGACCGCTACGGGCAC
CGCATCGACCTGGTCGAATTCCACCCGGCGTATCACCAGTTGATGAGCACGGCCATCGCGCATGGCATCCCGTCGTTGCC
GTGGACCGAGCCGCAGCCCGGTGCTCACGTGGCGCGTGCGGCCATGAGCTATCTGCACACCCAGGCTGAGCCCGGCAGCG
GCTGCCCGCTGACCATGACCTTTGCCAGCGTGCCTGCGCTCAGGCTGCAGCCGGATCTGGCTGAAATCTGGCTGCCCAAG
GTGCTGTCGACTGAGTACGATCCGCGCAACGTGGGCATTGCGCACAAGAACGGCGCGACCATCGGCATGGCCATGACCGA
GAAGCAGGGCGGCACCGACGTGCGGGCCAATACCACGCGTGCGTTTTCGGTGGGGGCCGGCGGCCCCGGCCAGGCCTACG
AACTGGTCGGGCATAAATGGTTCTGCTCGGCACCCATGTGCGATGCCTTCCTGACCCTGGCGCAGACCGACAAGGGCCTC
AGCTGTTTTCTGCTGCCACGCCACCGGCCTGATGACACGCGTAACGAGTTCTACATTCAGCGCCTGAAAAACAAGCTCGG
CAACTGGTCCAACGCCTCCAGCGAGGTCGAGTTTCGCGGTGCGCTGGCATGGATGATCGGCGAAGAAGGGCGCGGCGTGC
CGACCATCATCGAAATGGTCGCCATGACCCGTTTCGACTGCATGATCGGCTCCAGTGCCCTGATGCGTCAGGCGCTGACT
CAGGCGACTCATCATTGCGCGCACCGTGCGGTCAGTGGCCGGTTGCTCGCCGAGCAGCCGTTGATGCAGAACGTGCTGGC
TGACCTGGCACTGGAAAGCGAGGCCGCGCTGGCCCTGACCCTGCGTGTGGGGCGCGCGCTTGACCACCTGGATGATGATC
ACGAAAAGCGTTTTGTGCGCCTGGTCACCGCAGTGGGCAAATACTGGATCTGCAAGCGCGCCCCGGCCATGATCAACGAA
GCCGCCGAGTGCCTGGGTGGCGCCGGTTATGTCGAGGACAGCATTGTGCCCCGCTTGTACCGCGAAGCGCCGGTCAACTC
GACATGGGAAGGCTCCGGCAACGTGCAATGCCTGGACGTGCTGCGAACCCTGTCCAAGGAGCCCGGCGCACTCGATGCGC
TGTTCGACGAGCTGGGCGACGGGCATGGCGACCGGCATCTGGCGGCGCACATCGGCTCGCTCAAGGCCGCGTTTCAGGAC
ACCGGCGACATTCAGTATCGCGCCCGCCAGTTGACCGAAGACATCGCCATCGCCTTGCAGGGCAAGCTGCTGCTGGAAGC
GGGTAACGCGGCGGTCAGTGACGGCTTCATTGCCGGTCGGATAGCGTCCGGCGGGCGGGTGTATGGCGCATTGCCCACGG
GCGTTGACGTAGAAACATTGCTGCAAAGGTCCTCGCCGCAGGTGGCATGA

Upstream 100 bases:

>100_bases
TTAAAGCGCCGACCGTTAGGCGGCTGCGGTACTTTTGCGAGGGCCGGGTGCGTGATTCACTGTGTGCATATTGCGTGTGT
ATGCAGGCAGGAGATGACTC

Downstream 100 bases:

>100_bases
GCACGCGAACCCGTTACGATGCACGTCTGCAAGATCAGACAGGACATGAATCGTGACCCAAGCCTTTGTTGTTGTCGACA
CCGCCGAGCAGGCTGTAGAA

Product: Acyl-CoA dehydrogenase, C-terminal:Acyl-CoA dehydrogenase, central region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MNLNQFAETHEVTNQPPPLDGANLYRIDVPLQEWSSRFGAGWAQPRIDAYGALAGGPLMAAGFLANQHRPEFASHDRYGH
RIDLVEFHPAYHQLMSTAIAHGIPSLPWTEPQPGAHVARAAMSYLHTQAEPGSGCPLTMTFASVPALRLQPDLAEIWLPK
VLSTEYDPRNVGIAHKNGATIGMAMTEKQGGTDVRANTTRAFSVGAGGPGQAYELVGHKWFCSAPMCDAFLTLAQTDKGL
SCFLLPRHRPDDTRNEFYIQRLKNKLGNWSNASSEVEFRGALAWMIGEEGRGVPTIIEMVAMTRFDCMIGSSALMRQALT
QATHHCAHRAVSGRLLAEQPLMQNVLADLALESEAALALTLRVGRALDHLDDDHEKRFVRLVTAVGKYWICKRAPAMINE
AAECLGGAGYVEDSIVPRLYREAPVNSTWEGSGNVQCLDVLRTLSKEPGALDALFDELGDGHGDRHLAAHIGSLKAAFQD
TGDIQYRARQLTEDIAIALQGKLLLEAGNAAVSDGFIAGRIASGGRVYGALPTGVDVETLLQRSSPQVA

Sequences:

>Translated_549_residues
MNLNQFAETHEVTNQPPPLDGANLYRIDVPLQEWSSRFGAGWAQPRIDAYGALAGGPLMAAGFLANQHRPEFASHDRYGH
RIDLVEFHPAYHQLMSTAIAHGIPSLPWTEPQPGAHVARAAMSYLHTQAEPGSGCPLTMTFASVPALRLQPDLAEIWLPK
VLSTEYDPRNVGIAHKNGATIGMAMTEKQGGTDVRANTTRAFSVGAGGPGQAYELVGHKWFCSAPMCDAFLTLAQTDKGL
SCFLLPRHRPDDTRNEFYIQRLKNKLGNWSNASSEVEFRGALAWMIGEEGRGVPTIIEMVAMTRFDCMIGSSALMRQALT
QATHHCAHRAVSGRLLAEQPLMQNVLADLALESEAALALTLRVGRALDHLDDDHEKRFVRLVTAVGKYWICKRAPAMINE
AAECLGGAGYVEDSIVPRLYREAPVNSTWEGSGNVQCLDVLRTLSKEPGALDALFDELGDGHGDRHLAAHIGSLKAAFQD
TGDIQYRARQLTEDIAIALQGKLLLEAGNAAVSDGFIAGRIASGGRVYGALPTGVDVETLLQRSSPQVA
>Mature_549_residues
MNLNQFAETHEVTNQPPPLDGANLYRIDVPLQEWSSRFGAGWAQPRIDAYGALAGGPLMAAGFLANQHRPEFASHDRYGH
RIDLVEFHPAYHQLMSTAIAHGIPSLPWTEPQPGAHVARAAMSYLHTQAEPGSGCPLTMTFASVPALRLQPDLAEIWLPK
VLSTEYDPRNVGIAHKNGATIGMAMTEKQGGTDVRANTTRAFSVGAGGPGQAYELVGHKWFCSAPMCDAFLTLAQTDKGL
SCFLLPRHRPDDTRNEFYIQRLKNKLGNWSNASSEVEFRGALAWMIGEEGRGVPTIIEMVAMTRFDCMIGSSALMRQALT
QATHHCAHRAVSGRLLAEQPLMQNVLADLALESEAALALTLRVGRALDHLDDDHEKRFVRLVTAVGKYWICKRAPAMINE
AAECLGGAGYVEDSIVPRLYREAPVNSTWEGSGNVQCLDVLRTLSKEPGALDALFDELGDGHGDRHLAAHIGSLKAAFQD
TGDIQYRARQLTEDIAIALQGKLLLEAGNAAVSDGFIAGRIASGGRVYGALPTGVDVETLLQRSSPQVA

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=274, Percent_Identity=28.4671532846715, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI4501859, Length=273, Percent_Identity=26.3736263736264, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI87082384, Length=472, Percent_Identity=47.6694915254237, Blast_Score=409, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI86563383, Length=467, Percent_Identity=29.5503211991435, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI86563381, Length=467, Percent_Identity=29.5503211991435, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17538396, Length=300, Percent_Identity=26, Blast_Score=79, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17508101, Length=273, Percent_Identity=25.2747252747253, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281363737, Length=344, Percent_Identity=22.9651162790698, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356377, Length=274, Percent_Identity=25.1824817518248, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21355753, Length=309, Percent_Identity=24.9190938511327, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 59511; Mature: 59511

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNQFAETHEVTNQPPPLDGANLYRIDVPLQEWSSRFGAGWAQPRIDAYGALAGGPLMA
CCHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCCCHHHHHCCCCCHHHH
AGFLANQHRPEFASHDRYGHRIDLVEFHPAYHQLMSTAIAHGIPSLPWTEPQPGAHVARA
HHHHHCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
AMSYLHTQAEPGSGCPLTMTFASVPALRLQPDLAEIWLPKVLSTEYDPRNVGIAHKNGAT
HHHHHHHCCCCCCCCCEEEEHHHCCCCEECCCHHHHHHHHHHCCCCCCCCCCEEECCCCE
IGMAMTEKQGGTDVRANTTRAFSVGAGGPGQAYELVGHKWFCSAPMCDAFLTLAQTDKGL
EEEEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHCCCEEECCCHHHHHHHHHHCCCCC
SCFLLPRHRPDDTRNEFYIQRLKNKLGNWSNASSEVEFRGALAWMIGEEGRGVPTIIEMV
EEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHH
AMTRFDCMIGSSALMRQALTQATHHCAHRAVSGRLLAEQPLMQNVLADLALESEAALALT
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEH
LRVGRALDHLDDDHEKRFVRLVTAVGKYWICKRAPAMINEAAECLGGAGYVEDSIVPRLY
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHH
REAPVNSTWEGSGNVQCLDVLRTLSKEPGALDALFDELGDGHGDRHLAAHIGSLKAAFQD
HHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
TGDIQYRARQLTEDIAIALQGKLLLEAGNAAVSDGFIAGRIASGGRVYGALPTGVDVETL
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEECCCCEEEECCCCCCCHHHH
LQRSSPQVA
HHCCCCCCC
>Mature Secondary Structure
MNLNQFAETHEVTNQPPPLDGANLYRIDVPLQEWSSRFGAGWAQPRIDAYGALAGGPLMA
CCHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHCCCCCCCCHHHHHCCCCCHHHH
AGFLANQHRPEFASHDRYGHRIDLVEFHPAYHQLMSTAIAHGIPSLPWTEPQPGAHVARA
HHHHHCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHH
AMSYLHTQAEPGSGCPLTMTFASVPALRLQPDLAEIWLPKVLSTEYDPRNVGIAHKNGAT
HHHHHHHCCCCCCCCCEEEEHHHCCCCEECCCHHHHHHHHHHCCCCCCCCCCEEECCCCE
IGMAMTEKQGGTDVRANTTRAFSVGAGGPGQAYELVGHKWFCSAPMCDAFLTLAQTDKGL
EEEEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHCCCEEECCCHHHHHHHHHHCCCCC
SCFLLPRHRPDDTRNEFYIQRLKNKLGNWSNASSEVEFRGALAWMIGEEGRGVPTIIEMV
EEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHH
AMTRFDCMIGSSALMRQALTQATHHCAHRAVSGRLLAEQPLMQNVLADLALESEAALALT
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCEEEH
LRVGRALDHLDDDHEKRFVRLVTAVGKYWICKRAPAMINEAAECLGGAGYVEDSIVPRLY
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHH
REAPVNSTWEGSGNVQCLDVLRTLSKEPGALDALFDELGDGHGDRHLAAHIGSLKAAFQD
HHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
TGDIQYRARQLTEDIAIALQGKLLLEAGNAAVSDGFIAGRIASGGRVYGALPTGVDVETL
CCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEECCCCEEEECCCCCCCHHHH
LQRSSPQVA
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]