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The map label for this gene is aes [H]

Identifier: 66047557

GI number: 66047557

Start: 5181945

End: 5182838

Strand: Reverse

Name: aes [H]

Synonym: Psyr_4330

Alternate gene names: 66047557

Gene position: 5182838-5181945 (Counterclockwise)

Preceding gene: 66047558

Following gene: 66047554

Centisome position: 85.05

GC content: 61.63

Gene sequence:

>894_bases
ATGCCGCGTTTCCAGATTCGCAATCGCGTCACGCCCCGGCTGATTCAGGCGCTGTTACGTGCAGCTCAGATCGGCAGCGC
CCTGAAACCGGGAGGGCATGACCTGCGCATTGAGAAAAGAACGGTCAGCTCGGATAACGTACCGGTGCCCTTGCGCATCA
TCCGCCCCAAAGGCAAACCCCGGGGCGTGGTGTTCGACATCCACGGCGGCGGATGGGTGATCGGCAATGCGCAGATGAAC
GATGATCTCAACGTCGCCATGGTCAATGCCTGCGACGTGGCCATTGTTTCGGTTGATTATCGACTCGCTGTGACAACCCC
CATTGAGGGCCTGATGGAGGACTGTTTTTCTGCCGCCTGCTGGCTGTTGGGCAAAGACTGCGAAGAGTTTGCCGGCCTGC
CGGTTATCGTGGTCGGCGAATCCGCTGGCGGGCATCTTGCCGCAGCCACCCTCCTGAAATTGAAAAACCGACCTGATCTG
CTCGAGCGGATAGTGGGTACGGTCCTGTATTACGGCGTCTACGACCTGACGGGCACCATGAGCGTGCGTACCGCAGGGCC
CGAGACGCTGGTGCTGGACGGTCCGGGCATGGTCGGCGCCATGCGCGCGCTCACCCCTGATCGAAGCGACGATAAACGCC
GTGAACCGCCATTGTCACCACTGTATGGCGATTTGACCGGCCTTCCGCCCGCACTGATGTTCGTCGGAGAGATCGACCCG
CTGCTGGATGACACACTGCAAATGGCCGAGCGCTGGGCCAACTCGGCAGAGGTCGAAATGCACCTCATGCCCGAGTCGCC
GCACGGCTTCATCCACTTCCCGACCACGTTGGCGCGCAAGGCGCTGGCGCGCAGCCGCGAGTGGATCAATGAGCGGATCG
ATGCGCTGGGTTGA

Upstream 100 bases:

>100_bases
CAGCCTGACAAGAGAGCAGAAATTGGACACAAAACAGCTTTGGCCTTGCAGTGAACAGGAGTTGGTAGAAGTACGACGGT
TCAATAAAACCCTCTCGCGG

Downstream 100 bases:

>100_bases
GCCCGCCCCTCAACCTATCTCCGCGACCCACTTCGATACCGGGTCGCCACTGCTCAAGCCCGGCTGCACAAGACCGTCGA
TCATGAAGGTCGGCGAGACG

Product: hypothetical protein

Products: alcohol; a carboxylate [C]

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MPRFQIRNRVTPRLIQALLRAAQIGSALKPGGHDLRIEKRTVSSDNVPVPLRIIRPKGKPRGVVFDIHGGGWVIGNAQMN
DDLNVAMVNACDVAIVSVDYRLAVTTPIEGLMEDCFSAACWLLGKDCEEFAGLPVIVVGESAGGHLAAATLLKLKNRPDL
LERIVGTVLYYGVYDLTGTMSVRTAGPETLVLDGPGMVGAMRALTPDRSDDKRREPPLSPLYGDLTGLPPALMFVGEIDP
LLDDTLQMAERWANSAEVEMHLMPESPHGFIHFPTTLARKALARSREWINERIDALG

Sequences:

>Translated_297_residues
MPRFQIRNRVTPRLIQALLRAAQIGSALKPGGHDLRIEKRTVSSDNVPVPLRIIRPKGKPRGVVFDIHGGGWVIGNAQMN
DDLNVAMVNACDVAIVSVDYRLAVTTPIEGLMEDCFSAACWLLGKDCEEFAGLPVIVVGESAGGHLAAATLLKLKNRPDL
LERIVGTVLYYGVYDLTGTMSVRTAGPETLVLDGPGMVGAMRALTPDRSDDKRREPPLSPLYGDLTGLPPALMFVGEIDP
LLDDTLQMAERWANSAEVEMHLMPESPHGFIHFPTTLARKALARSREWINERIDALG
>Mature_296_residues
PRFQIRNRVTPRLIQALLRAAQIGSALKPGGHDLRIEKRTVSSDNVPVPLRIIRPKGKPRGVVFDIHGGGWVIGNAQMND
DLNVAMVNACDVAIVSVDYRLAVTTPIEGLMEDCFSAACWLLGKDCEEFAGLPVIVVGESAGGHLAAATLLKLKNRPDLL
ERIVGTVLYYGVYDLTGTMSVRTAGPETLVLDGPGMVGAMRALTPDRSDDKRREPPLSPLYGDLTGLPPALMFVGEIDPL
LDDTLQMAERWANSAEVEMHLMPESPHGFIHFPTTLARKALARSREWINERIDALG

Specific function: Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Escherichia coli, GI1786682, Length=247, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI72001146, Length=90, Percent_Identity=42.2222222222222, Blast_Score=67, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: 3.1.1.- [C]

Molecular weight: Translated: 32377; Mature: 32246

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFQIRNRVTPRLIQALLRAAQIGSALKPGGHDLRIEKRTVSSDNVPVPLRIIRPKGKP
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCC
RGVVFDIHGGGWVIGNAQMNDDLNVAMVNACDVAIVSVDYRLAVTTPIEGLMEDCFSAAC
CEEEEEECCCCEEEECCEECCCCCEEEEEECEEEEEEEEEEEEEECCHHHHHHHHHHHHH
WLLGKDCEEFAGLPVIVVGESAGGHLAAATLLKLKNRPDLLERIVGTVLYYGVYDLTGTM
HHHCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCE
SVRTAGPETLVLDGPGMVGAMRALTPDRSDDKRREPPLSPLYGDLTGLPPALMFVGEIDP
EEEECCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCH
LLDDTLQMAERWANSAEVEMHLMPESPHGFIHFPTTLARKALARSREWINERIDALG
HHHHHHHHHHHCCCCCEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRFQIRNRVTPRLIQALLRAAQIGSALKPGGHDLRIEKRTVSSDNVPVPLRIIRPKGKP
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCCCCEEEEEECCCCCC
RGVVFDIHGGGWVIGNAQMNDDLNVAMVNACDVAIVSVDYRLAVTTPIEGLMEDCFSAAC
CEEEEEECCCCEEEECCEECCCCCEEEEEECEEEEEEEEEEEEEECCHHHHHHHHHHHHH
WLLGKDCEEFAGLPVIVVGESAGGHLAAATLLKLKNRPDLLERIVGTVLYYGVYDLTGTM
HHHCCCHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCE
SVRTAGPETLVLDGPGMVGAMRALTPDRSDDKRREPPLSPLYGDLTGLPPALMFVGEIDP
EEEECCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCH
LLDDTLQMAERWANSAEVEMHLMPESPHGFIHFPTTLARKALARSREWINERIDALG
HHHHHHHHHHHCCCCCEEEEEEECCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA