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The map label for this gene is rlmG [H]

Identifier: 66047506

GI number: 66047506

Start: 5103190

End: 5104314

Strand: Direct

Name: rlmG [H]

Synonym: Psyr_4279

Alternate gene names: 66047506

Gene position: 5103190-5104314 (Clockwise)

Preceding gene: 66047505

Following gene: 66047513

Centisome position: 83.75

GC content: 63.91

Gene sequence:

>1125_bases
ATGCCCCTGCTCATCAGTCCCTTCGCTGAACTTGATCTCATTCGCCAACCCGAGCAACAGGATGAGCCCCTGCAGGCATT
CGATGCCGCCGACGAGTACCTGCTCAATCATGTTGCACAGGCAGGGCTCAGCCTGCCCAGCCGGGTTCTGGTGCTCAATG
ACAGTTTCGGCGCGCTGGCGGCGAGTCTCGCGCCGCATGCCACGGTGATCAGCAGTACCGACTCGTTTCTGGCGGCGCAG
GCGCTGGAAAAGAATCTGGCGCGCAACGGCATGAGCTACGACGCAGTACCGCACATCCCGGCCAGCGAAGCGTTGCAGGG
GCCCTTCGACTGGGTGCTGATCCGGGTGCCCAAGACCCTGGCGCTGCTGGAAGAGCAACTGATACGCCTGCAAGGCCAGC
TGGCCCCCGGCGCTCGGGTCATTGCTGCGGCAATGGTCAAGCATTTGCCGCGTTCGGCGGGCGACTTGCTGGAGGAATAT
GTAGGGCCGGTGCAGGCCTCGCTGGCAGTGAAAAAAGCCAGGCTGCTGTTCGCCACGCCACAGCCCATGGAAGTGCGCAC
CTCGCCCTATCCGACGCGCTACCGGCTGGAGGAGCCGGCCATCGAACTGCTCAACCATGCCAATGTGTTTTGCCGCGACG
GGCTGGACATCGGCACTCGCGCCTTCCTGCCGCATCTGCCGAAAAACCTTGGCACGGCAAGGGTCGCAGACCTGGGTTGC
GGCAACGGCGTACTGGCCATTGCCAGCGCGCTGGACAACCCGCAAGCGCACTACACGCTGGTCGACGAGTCGTTCATGGC
CGTGAAATCGGCAGCCGAGAACTGGCGCGCGACGCTGGGTGATCGCGACGTCCGGGTTCGGGCTGGCGACGGTCTGGAGA
TGCAGGAGCCTGACTCGCTGGATGTGGTGCTGTGCAATCCGCCCTTCCACCAGCAGCAAGTGGTCGGCGACTTTCTCGCC
TGGCGGATGTTTCTGCAGGCGCGTGCCGCGCTGGTGACCGGCGGGGCGCTGTACATCGTCGGCAATCGCCACCTGGGTTA
TCACACCAAGCTGTCGCGCCTGTTCCGCGGCGTCGAACAAGTGGCCGCCACGCCGAAATTCGTGATTCTGAAAGCCCGCA
AGTAA

Upstream 100 bases:

>100_bases
GGTATCGAAACGAAAAAATACGTAAAATCGTTTGTCTCAGCGAGCCCACCTGTCATCGGGCTCACTGACATACCTTCGAT
TGCACAGAGTTCTCCCGCCA

Downstream 100 bases:

>100_bases
CCCACGCTCACGACAAAAAAAAGACCCCCTTGCCACGCGAGTGGCAAGAGGGTCGCAAAACGTGTCCGCAGACACGAACG
GGAATTCAGTATCAGTGTGT

Product: rRNA (guanine-N(2)-)-methyltransferase

Products: NA

Alternate protein names: 23S rRNA m2G1835 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rlmG [H]

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MPLLISPFAELDLIRQPEQQDEPLQAFDAADEYLLNHVAQAGLSLPSRVLVLNDSFGALAASLAPHATVISSTDSFLAAQ
ALEKNLARNGMSYDAVPHIPASEALQGPFDWVLIRVPKTLALLEEQLIRLQGQLAPGARVIAAAMVKHLPRSAGDLLEEY
VGPVQASLAVKKARLLFATPQPMEVRTSPYPTRYRLEEPAIELLNHANVFCRDGLDIGTRAFLPHLPKNLGTARVADLGC
GNGVLAIASALDNPQAHYTLVDESFMAVKSAAENWRATLGDRDVRVRAGDGLEMQEPDSLDVVLCNPPFHQQQVVGDFLA
WRMFLQARAALVTGGALYIVGNRHLGYHTKLSRLFRGVEQVAATPKFVILKARK

Sequences:

>Translated_374_residues
MPLLISPFAELDLIRQPEQQDEPLQAFDAADEYLLNHVAQAGLSLPSRVLVLNDSFGALAASLAPHATVISSTDSFLAAQ
ALEKNLARNGMSYDAVPHIPASEALQGPFDWVLIRVPKTLALLEEQLIRLQGQLAPGARVIAAAMVKHLPRSAGDLLEEY
VGPVQASLAVKKARLLFATPQPMEVRTSPYPTRYRLEEPAIELLNHANVFCRDGLDIGTRAFLPHLPKNLGTARVADLGC
GNGVLAIASALDNPQAHYTLVDESFMAVKSAAENWRATLGDRDVRVRAGDGLEMQEPDSLDVVLCNPPFHQQQVVGDFLA
WRMFLQARAALVTGGALYIVGNRHLGYHTKLSRLFRGVEQVAATPKFVILKARK
>Mature_373_residues
PLLISPFAELDLIRQPEQQDEPLQAFDAADEYLLNHVAQAGLSLPSRVLVLNDSFGALAASLAPHATVISSTDSFLAAQA
LEKNLARNGMSYDAVPHIPASEALQGPFDWVLIRVPKTLALLEEQLIRLQGQLAPGARVIAAAMVKHLPRSAGDLLEEYV
GPVQASLAVKKARLLFATPQPMEVRTSPYPTRYRLEEPAIELLNHANVFCRDGLDIGTRAFLPHLPKNLGTARVADLGCG
NGVLAIASALDNPQAHYTLVDESFMAVKSAAENWRATLGDRDVRVRAGDGLEMQEPDSLDVVLCNPPFHQQQVVGDFLAW
RMFLQARAALVTGGALYIVGNRHLGYHTKLSRLFRGVEQVAATPKFVILKARK

Specific function: Specifically methylates the guanosine in position 1835 (m2G1835) of 23S rRNA [H]

COG id: COG2813

COG function: function code J; 16S RNA G1207 methylase RsmC

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmG family [H]

Homologues:

Organism=Escherichia coli, GI87082206, Length=377, Percent_Identity=42.1750663129974, Blast_Score=265, Evalue=4e-72,
Organism=Escherichia coli, GI1790830, Length=353, Percent_Identity=28.328611898017, Blast_Score=85, Evalue=9e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR017237
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.174 [H]

Molecular weight: Translated: 40736; Mature: 40605

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLISPFAELDLIRQPEQQDEPLQAFDAADEYLLNHVAQAGLSLPSRVLVLNDSFGALA
CCEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHH
ASLAPHATVISSTDSFLAAQALEKNLARNGMSYDAVPHIPASEALQGPFDWVLIRVPKTL
HHHCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCEEEEEECCHHH
ALLEEQLIRLQGQLAPGARVIAAAMVKHLPRSAGDLLEEYVGPVQASLAVKKARLLFATP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHEEEECC
QPMEVRTSPYPTRYRLEEPAIELLNHANVFCRDGLDIGTRAFLPHLPKNLGTARVADLGC
CCCCCCCCCCCCCEECCHHHHHHHHCCCEEEECCCCCCHHHHHHHCCCCCCCCHHHHCCC
GNGVLAIASALDNPQAHYTLVDESFMAVKSAAENWRATLGDRDVRVRAGDGLEMQEPDSL
CCCHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCC
DVVLCNPPFHQQQVVGDFLAWRMFLQARAALVTGGALYIVGNRHLGYHTKLSRLFRGVEQ
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEECCEEEEEECCCCCHHHHHHHHHHHHHH
VAATPKFVILKARK
HHCCCCEEEEEECC
>Mature Secondary Structure 
PLLISPFAELDLIRQPEQQDEPLQAFDAADEYLLNHVAQAGLSLPSRVLVLNDSFGALA
CEEECCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHH
ASLAPHATVISSTDSFLAAQALEKNLARNGMSYDAVPHIPASEALQGPFDWVLIRVPKTL
HHHCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCEEEEEECCHHH
ALLEEQLIRLQGQLAPGARVIAAAMVKHLPRSAGDLLEEYVGPVQASLAVKKARLLFATP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHCHHHHHHHHHHHHEEEECC
QPMEVRTSPYPTRYRLEEPAIELLNHANVFCRDGLDIGTRAFLPHLPKNLGTARVADLGC
CCCCCCCCCCCCCEECCHHHHHHHHCCCEEEECCCCCCHHHHHHHCCCCCCCCHHHHCCC
GNGVLAIASALDNPQAHYTLVDESFMAVKSAAENWRATLGDRDVRVRAGDGLEMQEPDSL
CCCHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCC
DVVLCNPPFHQQQVVGDFLAWRMFLQARAALVTGGALYIVGNRHLGYHTKLSRLFRGVEQ
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHEECCEEEEEECCCCCHHHHHHHHHHHHHH
VAATPKFVILKARK
HHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA