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The map label for this gene is yicO [C]

Identifier: 66047513

GI number: 66047513

Start: 5111500

End: 5112795

Strand: Direct

Name: yicO [C]

Synonym: Psyr_4286

Alternate gene names: 66047513

Gene position: 5111500-5112795 (Clockwise)

Preceding gene: 66047506

Following gene: 66047514

Centisome position: 83.88

GC content: 62.11

Gene sequence:

>1296_bases
ATGCTGGAAAGGCTGTTTCAACTCAAGGCACACAACACCAACGTGCGAACCGAGATTCTTGCGGGCGTCACGACTTTCCT
GGCGATGGCTTACATCCTGTTCGTCAACCCGAGCATCCTCGGCGAAACCGGCATGGACAAGGGCGCGGTATTCGTCGCCA
CCTGCCTGGCGGCGGCCATCGGCTCGACAGTGATGGGCCTGATCGCCAACTACCCGATCGCCCTGGCACCGGGCATGGGC
CTGAACGCCTTCTTTACCTACACCGTGGTCCTGCACATGGGCCACAGCTGGCAGGTAGCGCTGGGCGCGGTGTTCATTTC
AGCGGTGATGTTCTTCATCCTGTCGATCTTCCGGATCCGTGAATGGATCATCAATAGCATTCCCCTGCCCCTGCGTTCGG
CGATTGCGGCCGGTATCGGCCTGTTTCTGGCGCTGATCGCCCTGCATAACGCCGGTATTGTGGTCAGCAACCCGGCGACC
ATGGTCGGCATGGGCGATCTCAAGCAGCCAGCCCCGGTACTGGCGACGCTGGGCTTCTTTCTGATCGTGGCCCTGGATTA
CCTCAAGGTGCGCGGCGCCGTGCTGATCGGCATCCTCGCGGTGACCCTGGTGTCTATCGCCCTGGGCTTCTCACCGTTTG
GCGGTGTGGTGTCGATGCCGCCTTCGCTGGCACCGACCTTCATGCAACTGGACATCATGGGCGCGCTGGACGTCGGTCTG
GTCAGCATCATCTTCGCTTTCCTGTTCGTCGACATCTTCGACAACTCCGGCACGCTGATCGGCGTGGCCAAACGCGCCGG
GCTGATGGGCAAGGACGGGCACATGCCGAAGATGGGCCGTGCGCTGATCGCCGACAGTACTGCCGCGATGGCCGGTTCCC
TGCTAGGCACCTCGACCACCACCAGCTACATCGAGTCGGCTGCAGGTGTGAGTGCCGGTGGCCGCACAGGTCTGACTGCA
GTGGTGGTCGCCGTGCTGTTCCTGCTGGCGCTGTTCTTCGCCCCGCTGGCCGGCAGCGTGCCCGCCTTCGCGACGGCCCC
CGCGCTGCTGTTCGTCGCTGTGTTGATGGCGTCTGGCATGGCGGAAATCGACTGGGATGACATTACGGTCGCAGCGCCAG
TAGTCATCACGGCCCTGGCCATGCCATTCACCTATTCCATCGCCAATGGCATTGCCTTTGGCTTCATTTCCTGGACAGCG
ATCAAGCTGCTGTCGGGACGCTGGCGCGAGCTGAATTCGGCGCTGGTGATCCTGTCGATCCTGTTCGTGATCAAGCTGGG
CTGGTTCAACGCATGA

Upstream 100 bases:

>100_bases
TTTTTCCGACCCGCAAAAATCAAACGGGCTGCCCTGCAGTCTGTGCATTGCTGTTGGAGTCGATCATTCACGACGCGCGC
CGCGTCACGGAGAGCCAGAC

Downstream 100 bases:

>100_bases
GTGTTCCCTTCGACCCTGCGAGCTACGACCGTCAGCTCGAAGAAAAAACCGTCCGCCTGCGCGAGTTGCTGGCGCCGTTC
GATGCTCCCGAGCCACAGGT

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MLERLFQLKAHNTNVRTEILAGVTTFLAMAYILFVNPSILGETGMDKGAVFVATCLAAAIGSTVMGLIANYPIALAPGMG
LNAFFTYTVVLHMGHSWQVALGAVFISAVMFFILSIFRIREWIINSIPLPLRSAIAAGIGLFLALIALHNAGIVVSNPAT
MVGMGDLKQPAPVLATLGFFLIVALDYLKVRGAVLIGILAVTLVSIALGFSPFGGVVSMPPSLAPTFMQLDIMGALDVGL
VSIIFAFLFVDIFDNSGTLIGVAKRAGLMGKDGHMPKMGRALIADSTAAMAGSLLGTSTTTSYIESAAGVSAGGRTGLTA
VVVAVLFLLALFFAPLAGSVPAFATAPALLFVAVLMASGMAEIDWDDITVAAPVVITALAMPFTYSIANGIAFGFISWTA
IKLLSGRWRELNSALVILSILFVIKLGWFNA

Sequences:

>Translated_431_residues
MLERLFQLKAHNTNVRTEILAGVTTFLAMAYILFVNPSILGETGMDKGAVFVATCLAAAIGSTVMGLIANYPIALAPGMG
LNAFFTYTVVLHMGHSWQVALGAVFISAVMFFILSIFRIREWIINSIPLPLRSAIAAGIGLFLALIALHNAGIVVSNPAT
MVGMGDLKQPAPVLATLGFFLIVALDYLKVRGAVLIGILAVTLVSIALGFSPFGGVVSMPPSLAPTFMQLDIMGALDVGL
VSIIFAFLFVDIFDNSGTLIGVAKRAGLMGKDGHMPKMGRALIADSTAAMAGSLLGTSTTTSYIESAAGVSAGGRTGLTA
VVVAVLFLLALFFAPLAGSVPAFATAPALLFVAVLMASGMAEIDWDDITVAAPVVITALAMPFTYSIANGIAFGFISWTA
IKLLSGRWRELNSALVILSILFVIKLGWFNA
>Mature_431_residues
MLERLFQLKAHNTNVRTEILAGVTTFLAMAYILFVNPSILGETGMDKGAVFVATCLAAAIGSTVMGLIANYPIALAPGMG
LNAFFTYTVVLHMGHSWQVALGAVFISAVMFFILSIFRIREWIINSIPLPLRSAIAAGIGLFLALIALHNAGIVVSNPAT
MVGMGDLKQPAPVLATLGFFLIVALDYLKVRGAVLIGILAVTLVSIALGFSPFGGVVSMPPSLAPTFMQLDIMGALDVGL
VSIIFAFLFVDIFDNSGTLIGVAKRAGLMGKDGHMPKMGRALIADSTAAMAGSLLGTSTTTSYIESAAGVSAGGRTGLTA
VVVAVLFLLALFFAPLAGSVPAFATAPALLFVAVLMASGMAEIDWDDITVAAPVVITALAMPFTYSIANGIAFGFISWTA
IKLLSGRWRELNSALVILSILFVIKLGWFNA

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=425, Percent_Identity=51.5294117647059, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI1790150, Length=431, Percent_Identity=50.8120649651972, Blast_Score=431, Evalue=1e-122,
Organism=Escherichia coli, GI1790499, Length=432, Percent_Identity=41.4351851851852, Blast_Score=291, Evalue=6e-80,
Organism=Escherichia coli, GI48994909, Length=427, Percent_Identity=38.6416861826698, Blast_Score=266, Evalue=1e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45011; Mature: 45011

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLERLFQLKAHNTNVRTEILAGVTTFLAMAYILFVNPSILGETGMDKGAVFVATCLAAAI
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHH
GSTVMGLIANYPIALAPGMGLNAFFTYTVVLHMGHSWQVALGAVFISAVMFFILSIFRIR
HHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EWIINSIPLPLRSAIAAGIGLFLALIALHNAGIVVSNPATMVGMGDLKQPAPVLATLGFF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEECCCCCCCHHHHHHHHHH
LIVALDYLKVRGAVLIGILAVTLVSIALGFSPFGGVVSMPPSLAPTFMQLDIMGALDVGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VSIIFAFLFVDIFDNSGTLIGVAKRAGLMGKDGHMPKMGRALIADSTAAMAGSLLGTSTT
HHHHHHHHHHHHHCCCCCEEEEHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCHH
TSYIESAAGVSAGGRTGLTAVVVAVLFLLALFFAPLAGSVPAFATAPALLFVAVLMASGM
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
AEIDWDDITVAAPVVITALAMPFTYSIANGIAFGFISWTAIKLLSGRWRELNSALVILSI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVIKLGWFNA
HHHHHHHCCCC
>Mature Secondary Structure
MLERLFQLKAHNTNVRTEILAGVTTFLAMAYILFVNPSILGETGMDKGAVFVATCLAAAI
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHHHHHH
GSTVMGLIANYPIALAPGMGLNAFFTYTVVLHMGHSWQVALGAVFISAVMFFILSIFRIR
HHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EWIINSIPLPLRSAIAAGIGLFLALIALHNAGIVVSNPATMVGMGDLKQPAPVLATLGFF
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEECCCCCCCHHHHHHHHHH
LIVALDYLKVRGAVLIGILAVTLVSIALGFSPFGGVVSMPPSLAPTFMQLDIMGALDVGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VSIIFAFLFVDIFDNSGTLIGVAKRAGLMGKDGHMPKMGRALIADSTAAMAGSLLGTSTT
HHHHHHHHHHHHHCCCCCEEEEHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCHH
TSYIESAAGVSAGGRTGLTAVVVAVLFLLALFFAPLAGSVPAFATAPALLFVAVLMASGM
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCC
AEIDWDDITVAAPVVITALAMPFTYSIANGIAFGFISWTAIKLLSGRWRELNSALVILSI
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVIKLGWFNA
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]