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The map label for this gene is dppC [H]

Identifier: 66047467

GI number: 66047467

Start: 5052641

End: 5053552

Strand: Direct

Name: dppC [H]

Synonym: Psyr_4240

Alternate gene names: 66047467

Gene position: 5052641-5053552 (Clockwise)

Preceding gene: 66047466

Following gene: 66047468

Centisome position: 82.92

GC content: 63.05

Gene sequence:

>912_bases
ATGAGCACCCCTACTCCTGCGGTAGCAGTCGATCAAAGCCTGCTTTACCCATCCCCGTACAAAGAATTCTGGCAAGCCTT
CTCGAAAAACAAAGGCGCGGTTGCCGGCCTGCTGTTCATGATCCTGATCGTGTTCTGCGCCCTGTTCGCGCCCTGGGTTG
CACCCCATGACCCGAGCGAGCAATACCGCGACTTCCTGCTGACGCCTCCGGTGTGGCTCGAAGGCGGCCAATGGCAATTC
ATCCTCGGTACCGACGAACTGGGCCGCGATCTGCTGTCACGTCTGATCCAGGGTTCGCGCCTGTCGCTGCTGATCGGTCT
GGCATCGGTGGTCATGTCGCTGATCCCCGGCATTCTGCTGGGCCTGCTGGCGGGCTTCTTCCCTCGCGTGCTCGGCCCTT
CGGTGATGCGCCTGATGGACATCATGCTCGCCCTGCCTTCGCTGCTGCTGGCTGTGGCCATCGTGGCGATCCTCGGCCCA
GGCCTGATCAATACCGTAATCGCCATCGCCATCGTGTCGCTGCCTTCCTATGTTCGTCTGACCCGCGCTGCGGTGATGGG
CGAGCTGAACCGCGACTACGTGACGGCTGCCCGTCTGGCTGGCGCCACACTGCCACGCCTGATGTTCATCACCGTGCTGC
CCAACTGCATGGCACCGCTGATCGTTCAGGCGACCCTGAGCTTCTCGTCGGCGATTCTCGATGCCGCAGCGCTGGGCTTC
CTGGGTCTGGGCGTACAGCCACCGACGCCTGAGTGGGGCACCATGCTCGCCTCGGCGCGCGACTACATCGAACGTGCCTG
GTGGGTCGTGAGCCTGCCCGGTCTGACCATTTTGCTCAGCGTGCTGGCAATCAACCTGATGGGCGACGGTCTGCGCGATG
CGCTGGACCCGAAACTCAAGAACGCCGCCTGA

Upstream 100 bases:

>100_bases
CTGCTGATCGCCTGTCTGGTGATCCTGGTCAATTTCGTGGTGGATATCCTCTACGGCTTTGCCAACCCACGCATTCGTCA
CCAGCGCTGAGATCATCGAT

Downstream 100 bases:

>100_bases
GGAGATTCGCATGTCACTTCTTGAAATCAAGAATCTCAACGTCCGCTTCGGCGACGCCAAGGCCGTACCTGTTGTGGACG
GCCTGTCCCTGAGCGTCGAA

Product: binding-protein dependent transport system inner membrane protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MSTPTPAVAVDQSLLYPSPYKEFWQAFSKNKGAVAGLLFMILIVFCALFAPWVAPHDPSEQYRDFLLTPPVWLEGGQWQF
ILGTDELGRDLLSRLIQGSRLSLLIGLASVVMSLIPGILLGLLAGFFPRVLGPSVMRLMDIMLALPSLLLAVAIVAILGP
GLINTVIAIAIVSLPSYVRLTRAAVMGELNRDYVTAARLAGATLPRLMFITVLPNCMAPLIVQATLSFSSAILDAAALGF
LGLGVQPPTPEWGTMLASARDYIERAWWVVSLPGLTILLSVLAINLMGDGLRDALDPKLKNAA

Sequences:

>Translated_303_residues
MSTPTPAVAVDQSLLYPSPYKEFWQAFSKNKGAVAGLLFMILIVFCALFAPWVAPHDPSEQYRDFLLTPPVWLEGGQWQF
ILGTDELGRDLLSRLIQGSRLSLLIGLASVVMSLIPGILLGLLAGFFPRVLGPSVMRLMDIMLALPSLLLAVAIVAILGP
GLINTVIAIAIVSLPSYVRLTRAAVMGELNRDYVTAARLAGATLPRLMFITVLPNCMAPLIVQATLSFSSAILDAAALGF
LGLGVQPPTPEWGTMLASARDYIERAWWVVSLPGLTILLSVLAINLMGDGLRDALDPKLKNAA
>Mature_302_residues
STPTPAVAVDQSLLYPSPYKEFWQAFSKNKGAVAGLLFMILIVFCALFAPWVAPHDPSEQYRDFLLTPPVWLEGGQWQFI
LGTDELGRDLLSRLIQGSRLSLLIGLASVVMSLIPGILLGLLAGFFPRVLGPSVMRLMDIMLALPSLLLAVAIVAILGPG
LINTVIAIAIVSLPSYVRLTRAAVMGELNRDYVTAARLAGATLPRLMFITVLPNCMAPLIVQATLSFSSAILDAAALGFL
GLGVQPPTPEWGTMLASARDYIERAWWVVSLPGLTILLSVLAINLMGDGLRDALDPKLKNAA

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789964, Length=284, Percent_Identity=62.3239436619718, Blast_Score=320, Evalue=8e-89,
Organism=Escherichia coli, GI1787054, Length=295, Percent_Identity=41.6949152542373, Blast_Score=223, Evalue=9e-60,
Organism=Escherichia coli, GI1787760, Length=265, Percent_Identity=45.2830188679245, Blast_Score=217, Evalue=8e-58,
Organism=Escherichia coli, GI1787549, Length=279, Percent_Identity=40.1433691756272, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1789889, Length=254, Percent_Identity=39.3700787401575, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1787498, Length=282, Percent_Identity=30.1418439716312, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1788505, Length=221, Percent_Identity=28.0542986425339, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32532; Mature: 32401

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPTPAVAVDQSLLYPSPYKEFWQAFSKNKGAVAGLLFMILIVFCALFAPWVAPHDPSE
CCCCCCCHHHCCHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHH
QYRDFLLTPPVWLEGGQWQFILGTDELGRDLLSRLIQGSRLSLLIGLASVVMSLIPGILL
HHHHHCCCCCCEEECCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GLLAGFFPRVLGPSVMRLMDIMLALPSLLLAVAIVAILGPGLINTVIAIAIVSLPSYVRL
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
TRAAVMGELNRDYVTAARLAGATLPRLMFITVLPNCMAPLIVQATLSFSSAILDAAALGF
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLGVQPPTPEWGTMLASARDYIERAWWVVSLPGLTILLSVLAINLMGDGLRDALDPKLK
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHCCCCC
NAA
CCC
>Mature Secondary Structure 
STPTPAVAVDQSLLYPSPYKEFWQAFSKNKGAVAGLLFMILIVFCALFAPWVAPHDPSE
CCCCCCHHHCCHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHH
QYRDFLLTPPVWLEGGQWQFILGTDELGRDLLSRLIQGSRLSLLIGLASVVMSLIPGILL
HHHHHCCCCCCEEECCCEEEEECCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GLLAGFFPRVLGPSVMRLMDIMLALPSLLLAVAIVAILGPGLINTVIAIAIVSLPSYVRL
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
TRAAVMGELNRDYVTAARLAGATLPRLMFITVLPNCMAPLIVQATLSFSSAILDAAALGF
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLGVQPPTPEWGTMLASARDYIERAWWVVSLPGLTILLSVLAINLMGDGLRDALDPKLK
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHHCCCCC
NAA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800; 8550458 [H]