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The map label for this gene is ftsW [H]

Identifier: 66047330

GI number: 66047330

Start: 4891990

End: 4893204

Strand: Reverse

Name: ftsW [H]

Synonym: Psyr_4103

Alternate gene names: 66047330

Gene position: 4893204-4891990 (Counterclockwise)

Preceding gene: 66047331

Following gene: 66047329

Centisome position: 80.3

GC content: 61.73

Gene sequence:

>1215_bases
ATGATCTTCGGTGTGATCAAGCCTTATCCATCGCCACTGATCAGCGGGCGCGGCATCGACCTCGATTTCCCGATGCTGGT
CGGCTGCCTGGCGCTGCTCGGCCTTGGCCTGGTAATGATTACCTCGGCTTCTTCGGAAGTGGCCGCGGTGCAGTCGGGCA
ACACGCTGTACATGATGACCCGTCACCTGGTTTATCTGCTGATCGGCCTGGGTGCCTGCGGCGTGACCATGATGATTCCG
GTGGCCACCTGGCAGCGCCTGGGCTGGATGATGCTGCTCGGTGCGTTCGGCCTGTTGCTGCTGGTACTGGTGCCGGGAAT
CGGGCGCGAGGTGAACGGTTCGATGCGCTGGATCGGCTTCGGCGCGTTCAACGTGCAGCCGTCGGAAATCGCCAAGGTGT
TTGTGGTGATCTTCCTTGCCGGCTACCTGATTCGTCAGCAGCAGGAAGTTCGCGAAAGCTGGATGGGCTTTTTCAAGCCG
TTCATCGTGCTGTTGCCGATGGCCGGTCTGCTGCTCATGGAGCCTGACTTCGGTGCCACCGTGGTCATGATGGGCGCCGC
GGCGGCCATGCTGTTTCTTGGCGGGGTCGGCCTGTTCCGCTTCTCGCTGATGGTGGTACTGGCGGTCGCTTCTGTGGTGG
TGCTGGTTCAGGCCCAACCTTACCGGATGGCGCGTCTGACCAACTTTACCGACCCGTGGGCCGACCAGTTCGGTTCCGGC
TATCAGTTGACCCAGGCGCTGATCGCCTTCGGTCGCGGCGAGTGGTTCGGCGTCGGGCTGGGCAACAGCGTGCAGAAGCA
GTTCTACCTTCCGGAAGCGCACACCGACTTCGTGTTCTCGGTCCTTGCAGAAGAGCTGGGCGTCGTGGGTTCGCTGATCA
CCGTCGCGCTGTTTCTGTTCGTCAGTATTCGCGGCATGTACATCGGCATGTGGGCCGAGCGCGCCAAGCAGTTCTTCGGT
GCCTACGTGGCCTACGGTCTGTCGTTCCTGTGGATCGGTCAGTTCCTGATCAACATCGGTGTGAACGTCGGCTTGCTGCC
CACCAAGGGCCTGACACTGCCGTTCCTCAGCTACGGCGGCAGCTCGCTGGTGATCTGCTGCGCGAGCCTCGGGCTGCTGC
TGCGCATCGAGTGGGAATCGCGCAACAACATGGGCAGTGAAGAAGCCGAGTTCAAGGAAAGCGACTTCGCCGAGGAGACG
CCCCATGGACGCTAA

Upstream 100 bases:

>100_bases
GCGACGCCGTATTGCTTTCTCCTGCATGCGCCAGTCTGGACATGTTCAAGAATTATGAAGAGCGCGGACGTGTGTTCGCG
CAGGCAGTGGAGTGCTTGTC

Downstream 100 bases:

>100_bases
TGTGCTGATCATGGCGGGCGGGACCGGCGGGCATGTATTCCCGGCGCTGGCCTGTGCCCGCGAGTTTCAGGCACGCGGCT
ACAAGGTCCATTGGCTGGGC

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MIFGVIKPYPSPLISGRGIDLDFPMLVGCLALLGLGLVMITSASSEVAAVQSGNTLYMMTRHLVYLLIGLGACGVTMMIP
VATWQRLGWMMLLGAFGLLLLVLVPGIGREVNGSMRWIGFGAFNVQPSEIAKVFVVIFLAGYLIRQQQEVRESWMGFFKP
FIVLLPMAGLLLMEPDFGATVVMMGAAAAMLFLGGVGLFRFSLMVVLAVASVVVLVQAQPYRMARLTNFTDPWADQFGSG
YQLTQALIAFGRGEWFGVGLGNSVQKQFYLPEAHTDFVFSVLAEELGVVGSLITVALFLFVSIRGMYIGMWAERAKQFFG
AYVAYGLSFLWIGQFLINIGVNVGLLPTKGLTLPFLSYGGSSLVICCASLGLLLRIEWESRNNMGSEEAEFKESDFAEET
PHGR

Sequences:

>Translated_404_residues
MIFGVIKPYPSPLISGRGIDLDFPMLVGCLALLGLGLVMITSASSEVAAVQSGNTLYMMTRHLVYLLIGLGACGVTMMIP
VATWQRLGWMMLLGAFGLLLLVLVPGIGREVNGSMRWIGFGAFNVQPSEIAKVFVVIFLAGYLIRQQQEVRESWMGFFKP
FIVLLPMAGLLLMEPDFGATVVMMGAAAAMLFLGGVGLFRFSLMVVLAVASVVVLVQAQPYRMARLTNFTDPWADQFGSG
YQLTQALIAFGRGEWFGVGLGNSVQKQFYLPEAHTDFVFSVLAEELGVVGSLITVALFLFVSIRGMYIGMWAERAKQFFG
AYVAYGLSFLWIGQFLINIGVNVGLLPTKGLTLPFLSYGGSSLVICCASLGLLLRIEWESRNNMGSEEAEFKESDFAEET
PHGR
>Mature_404_residues
MIFGVIKPYPSPLISGRGIDLDFPMLVGCLALLGLGLVMITSASSEVAAVQSGNTLYMMTRHLVYLLIGLGACGVTMMIP
VATWQRLGWMMLLGAFGLLLLVLVPGIGREVNGSMRWIGFGAFNVQPSEIAKVFVVIFLAGYLIRQQQEVRESWMGFFKP
FIVLLPMAGLLLMEPDFGATVVMMGAAAAMLFLGGVGLFRFSLMVVLAVASVVVLVQAQPYRMARLTNFTDPWADQFGSG
YQLTQALIAFGRGEWFGVGLGNSVQKQFYLPEAHTDFVFSVLAEELGVVGSLITVALFLFVSIRGMYIGMWAERAKQFFG
AYVAYGLSFLWIGQFLINIGVNVGLLPTKGLTLPFLSYGGSSLVICCASLGLLLRIEWESRNNMGSEEAEFKESDFAEET
PHGR

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=360, Percent_Identity=44.1666666666667, Blast_Score=295, Evalue=5e-81,
Organism=Escherichia coli, GI1786853, Length=334, Percent_Identity=35.0299401197605, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 44037; Mature: 44037

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFGVIKPYPSPLISGRGIDLDFPMLVGCLALLGLGLVMITSASSEVAAVQSGNTLYMMT
CCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEHHHH
RHLVYLLIGLGACGVTMMIPVATWQRLGWMMLLGAFGLLLLVLVPGIGREVNGSMRWIGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEE
GAFNVQPSEIAKVFVVIFLAGYLIRQQQEVRESWMGFFKPFIVLLPMAGLLLMEPDFGAT
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHH
VVMMGAAAAMLFLGGVGLFRFSLMVVLAVASVVVLVQAQPYRMARLTNFTDPWADQFGSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHCCCC
YQLTQALIAFGRGEWFGVGLGNSVQKQFYLPEAHTDFVFSVLAEELGVVGSLITVALFLF
HHHHHHHHHHCCCCEEEECCCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSIRGMYIGMWAERAKQFFGAYVAYGLSFLWIGQFLINIGVNVGLLPTKGLTLPFLSYGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHCCC
SSLVICCASLGLLLRIEWESRNNMGSEEAEFKESDFAEETPHGR
CHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIFGVIKPYPSPLISGRGIDLDFPMLVGCLALLGLGLVMITSASSEVAAVQSGNTLYMMT
CCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEHHHH
RHLVYLLIGLGACGVTMMIPVATWQRLGWMMLLGAFGLLLLVLVPGIGREVNGSMRWIGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEE
GAFNVQPSEIAKVFVVIFLAGYLIRQQQEVRESWMGFFKPFIVLLPMAGLLLMEPDFGAT
EECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHH
VVMMGAAAAMLFLGGVGLFRFSLMVVLAVASVVVLVQAQPYRMARLTNFTDPWADQFGSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHCCCC
YQLTQALIAFGRGEWFGVGLGNSVQKQFYLPEAHTDFVFSVLAEELGVVGSLITVALFLF
HHHHHHHHHHCCCCEEEECCCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSIRGMYIGMWAERAKQFFGAYVAYGLSFLWIGQFLINIGVNVGLLPTKGLTLPFLSYGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHCCC
SSLVICCASLGLLLRIEWESRNNMGSEEAEFKESDFAEETPHGR
CHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]