Click here to switch to the map view.

The map label for this gene is mucB [H]

Identifier: 66047183

GI number: 66047183

Start: 4704426

End: 4705385

Strand: Reverse

Name: mucB [H]

Synonym: Psyr_3956

Alternate gene names: 66047183

Gene position: 4705385-4704426 (Counterclockwise)

Preceding gene: 66047184

Following gene: 66047182

Centisome position: 77.22

GC content: 56.88

Gene sequence:

>960_bases
ATGCGAGCCGTCCCTCTACTGCCGTTACTGCTTGGTGGATGGCTTGCCCTCCCGGTACAGGCTGATGATGCGCAAGACGC
AATCAATCGTCTTGCCAAGGTTGATCAGCAGCAGAGCTATCAAGGTACGTTTGTATACGAGCGCAATGGTAGTTTTTCTA
CCCATCGAATCTGGCACCGCATAGCGGACGGTCATATTCAGGAGCGCCTGCTACAGCTTGATGGTTCCGCTCAGGAAGTA
TTGCGTGTTGACGGGTTCACTCAGTGCGTCAGCGGCACGCTGGAAGCGGGGGTGGCCAATCCGGCCGATTCTTCTGCCCG
CGCATTCGATGTCAAAAGACTATCCGCCTGGTACGACATGAAAATTGCCGGCAAATCCAGAGTGGCCGGTCGTCAGGCAA
CTATCGTTGCGCTGTCCCCCAAGGACCAGCATCGATACGGCCTCGAATTGCACCTGGATAACGAAACCGGTCTTGTGCTC
AAGTCGCTTCTGTTGAGTGAGAAGGGGCAGTTGCTCGAGCGTTTCCAGTTTACCGATCTCGATACCGCCAGCGTGCTGTC
CGAACAGATGCTCAAGACCAGTGCCGACTGCAAGCCTGTTTCTGTGGTGAAGACCAAGCCTGAGGCCTCCATCAGCCCTG
TGGCCTGGCACTCAGACTGGCTGCCGCCGGGTTTTGACGTCAGCAGCAGCGGTGTGCGCAAAGACGCTGCTACGCAGTCG
GCGGTGACGCATCTCATGTACAGCGACGGTCTGGCGCGTTTTTCGGTGTTCATCGAATCGGTGAAAGGTGGCGCGTCTTC
GGATATTCGCACTCAGCTAGGCCCGACAGTGGCCGTTTCCCGCCGTCTGACAACGCCGCAGGGCGACATGATGGTGACGG
TCGTCGGAGAAGTTCCGATGGGCACTGCAGAGCGCATAGCATTGTCGATGCGTAACGACGAACCTTCAGCCAATAAATAA

Upstream 100 bases:

>100_bases
GCTATCTGCGCCAGCACGCCCAGGAAGCAGCGTTGAAAGGTACTGAAAGCGCGCTGCCATACGCACGTGCTGCGAGCCTG
GAAAACCGTTAAGGAGGATC

Downstream 100 bases:

>100_bases
ACATTTGGAGTCACGGCTCCCGGGATGTAAAAATTTTCATCCTGGGTTAAAGAAGCCGCCAGGCCGCACTCAACCTGGCT
TGAGCAAAGGCGCTGAAATG

Product: MucB/RseB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MRAVPLLPLLLGGWLALPVQADDAQDAINRLAKVDQQQSYQGTFVYERNGSFSTHRIWHRIADGHIQERLLQLDGSAQEV
LRVDGFTQCVSGTLEAGVANPADSSARAFDVKRLSAWYDMKIAGKSRVAGRQATIVALSPKDQHRYGLELHLDNETGLVL
KSLLLSEKGQLLERFQFTDLDTASVLSEQMLKTSADCKPVSVVKTKPEASISPVAWHSDWLPPGFDVSSSGVRKDAATQS
AVTHLMYSDGLARFSVFIESVKGGASSDIRTQLGPTVAVSRRLTTPQGDMMVTVVGEVPMGTAERIALSMRNDEPSANK

Sequences:

>Translated_319_residues
MRAVPLLPLLLGGWLALPVQADDAQDAINRLAKVDQQQSYQGTFVYERNGSFSTHRIWHRIADGHIQERLLQLDGSAQEV
LRVDGFTQCVSGTLEAGVANPADSSARAFDVKRLSAWYDMKIAGKSRVAGRQATIVALSPKDQHRYGLELHLDNETGLVL
KSLLLSEKGQLLERFQFTDLDTASVLSEQMLKTSADCKPVSVVKTKPEASISPVAWHSDWLPPGFDVSSSGVRKDAATQS
AVTHLMYSDGLARFSVFIESVKGGASSDIRTQLGPTVAVSRRLTTPQGDMMVTVVGEVPMGTAERIALSMRNDEPSANK
>Mature_319_residues
MRAVPLLPLLLGGWLALPVQADDAQDAINRLAKVDQQQSYQGTFVYERNGSFSTHRIWHRIADGHIQERLLQLDGSAQEV
LRVDGFTQCVSGTLEAGVANPADSSARAFDVKRLSAWYDMKIAGKSRVAGRQATIVALSPKDQHRYGLELHLDNETGLVL
KSLLLSEKGQLLERFQFTDLDTASVLSEQMLKTSADCKPVSVVKTKPEASISPVAWHSDWLPPGFDVSSSGVRKDAATQS
AVTHLMYSDGLARFSVFIESVKGGASSDIRTQLGPTVAVSRRLTTPQGDMMVTVVGEVPMGTAERIALSMRNDEPSANK

Specific function: Negative regulator of the sigma factor AlgU. Plays a role in the differentiation of P.aeruginosa into the alginate- producing form. Inactivation of mucB causes conversion to mucoidy [H]

COG id: COG3026

COG function: function code T; Negative regulator of sigma E activity

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rseB family [H]

Homologues:

Organism=Escherichia coli, GI1788924, Length=283, Percent_Identity=28.6219081272085, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005588 [H]

Pfam domain/function: PF03888 MucB_RseB [H]

EC number: NA

Molecular weight: Translated: 34704; Mature: 34704

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVPLLPLLLGGWLALPVQADDAQDAINRLAKVDQQQSYQGTFVYERNGSFSTHRIWHR
CCCCCHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
IADGHIQERLLQLDGSAQEVLRVDGFTQCVSGTLEAGVANPADSSARAFDVKRLSAWYDM
HHCHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEE
KIAGKSRVAGRQATIVALSPKDQHRYGLELHLDNETGLVLKSLLLSEKGQLLERFQFTDL
EECCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
DTASVLSEQMLKTSADCKPVSVVKTKPEASISPVAWHSDWLPPGFDVSSSGVRKDAATQS
CHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHH
AVTHLMYSDGLARFSVFIESVKGGASSDIRTQLGPTVAVSRRLTTPQGDMMVTVVGEVPM
HHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHCCCCEEEHCCCCCCCCCEEEEEECCCCC
GTAERIALSMRNDEPSANK
CCHHHEEEEECCCCCCCCC
>Mature Secondary Structure
MRAVPLLPLLLGGWLALPVQADDAQDAINRLAKVDQQQSYQGTFVYERNGSFSTHRIWHR
CCCCCHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
IADGHIQERLLQLDGSAQEVLRVDGFTQCVSGTLEAGVANPADSSARAFDVKRLSAWYDM
HHCHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEE
KIAGKSRVAGRQATIVALSPKDQHRYGLELHLDNETGLVLKSLLLSEKGQLLERFQFTDL
EECCCCCCCCCEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
DTASVLSEQMLKTSADCKPVSVVKTKPEASISPVAWHSDWLPPGFDVSSSGVRKDAATQS
CHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHH
AVTHLMYSDGLARFSVFIESVKGGASSDIRTQLGPTVAVSRRLTTPQGDMMVTVVGEVPM
HHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHCCCCEEEHCCCCCCCCCEEEEEECCCCC
GTAERIALSMRNDEPSANK
CCHHHEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8412698; 8378309; 8444793; 10984043 [H]