Click here to switch to the map view.

The map label for this gene is era

Identifier: 66047177

GI number: 66047177

Start: 4697791

End: 4698693

Strand: Reverse

Name: era

Synonym: Psyr_3950

Alternate gene names: 66047177

Gene position: 4698693-4697791 (Counterclockwise)

Preceding gene: 66047178

Following gene: 66047176

Centisome position: 77.11

GC content: 59.69

Gene sequence:

>903_bases
ATGAATGATACAACCGCAACACGCTGTGGCTATGTTGCCATTGTCGGCCGTCCCAACGTAGGCAAGTCCACGCTGCTCAA
CCACATTCTCGGTCAGAAGCTCGCGATCACCTCGCGCAAGCCGCAGACCACGCGCCACAACATGCTGGGCATCAAGACCG
AGGGCGCCGTGCAGGCGATCTATGTCGACACTCCCGGTATGCACAAGAATGGCGAGAAAGCGCTCAACCGTTACATGAAC
AAGACCGCTTCGGCGGCGCTGAAGGACGTCGACGTGGTCATCTTCGTCGTCGATCGCACCCGCTGGACGGACGAAGACCA
GATGGTTCTGGAGCGCGTTCAGTATGTCCAGGGTCCGGTCATCCTGGCGATCAACAAGACCGATCGCATCGAGGACAAGA
GCGACCTGATGCCGCACTTGGAGTGGCTGCAGGGCCAGCTGCCGAATGCGTCCATCGTGCCGATCTCCGCGCAGCATGGC
CACAACCTCGAAGCGCTGGAAAGCCTGATTGCCTCGCATCTGCCGGAGAATGACCACTTCTTCCCGGAAGACCAGATCAC
CGATCGCAGCAGCCGCTTTCTGGCCGCCGAACTGGTTCGCGAGAAGATCATGCGCCAGCTGGGTGCCGAGCTTCCGTACC
AGATCACCGTCGAGATCGAAGAGTTCAAGCAGCAGGGCCGCACCCTGCATATCCACGCGCTGATTCTCGTCGAGCGCGAC
GGACAGAAGAAGATCATCATTGGCGACAAGGGCGATCGCATCAAGCGCATCGGCAGTGATGCGCGTCGTGACATGGAACT
GCTGTTCGACTCCAAGGTGATGCTCAACCTCTGGGTCAAGGTCAAAGGTGGCTGGTCCGATGACGAGCGCGCCCTGCGTT
CCCTTGGCTACGGCGACCTCTAA

Upstream 100 bases:

>100_bases
CTATTGAATGAAAAAAGCCGAGGACAGGGTGTCAGCCGCCGGATTGCCGAACAGGTAGCCGCCGCAGCAGCACTCATCGC
CCTGGGCGTGGAGAACGGTC

Downstream 100 bases:

>100_bases
GCTGTCCTTTCGCCCGACCTTTCGGTGGTCGGGCGAACACTTCCCTCTCGAGCCAGCCTGATGAGCACGCCCACCGGCCA
ACCTGCTTATGTGCTCCACA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MNDTTATRCGYVAIVGRPNVGKSTLLNHILGQKLAITSRKPQTTRHNMLGIKTEGAVQAIYVDTPGMHKNGEKALNRYMN
KTASAALKDVDVVIFVVDRTRWTDEDQMVLERVQYVQGPVILAINKTDRIEDKSDLMPHLEWLQGQLPNASIVPISAQHG
HNLEALESLIASHLPENDHFFPEDQITDRSSRFLAAELVREKIMRQLGAELPYQITVEIEEFKQQGRTLHIHALILVERD
GQKKIIIGDKGDRIKRIGSDARRDMELLFDSKVMLNLWVKVKGGWSDDERALRSLGYGDL

Sequences:

>Translated_300_residues
MNDTTATRCGYVAIVGRPNVGKSTLLNHILGQKLAITSRKPQTTRHNMLGIKTEGAVQAIYVDTPGMHKNGEKALNRYMN
KTASAALKDVDVVIFVVDRTRWTDEDQMVLERVQYVQGPVILAINKTDRIEDKSDLMPHLEWLQGQLPNASIVPISAQHG
HNLEALESLIASHLPENDHFFPEDQITDRSSRFLAAELVREKIMRQLGAELPYQITVEIEEFKQQGRTLHIHALILVERD
GQKKIIIGDKGDRIKRIGSDARRDMELLFDSKVMLNLWVKVKGGWSDDERALRSLGYGDL
>Mature_300_residues
MNDTTATRCGYVAIVGRPNVGKSTLLNHILGQKLAITSRKPQTTRHNMLGIKTEGAVQAIYVDTPGMHKNGEKALNRYMN
KTASAALKDVDVVIFVVDRTRWTDEDQMVLERVQYVQGPVILAINKTDRIEDKSDLMPHLEWLQGQLPNASIVPISAQHG
HNLEALESLIASHLPENDHFFPEDQITDRSSRFLAAELVREKIMRQLGAELPYQITVEIEEFKQQGRTLHIHALILVERD
GQKKIIIGDKGDRIKRIGSDARRDMELLFDSKVMLNLWVKVKGGWSDDERALRSLGYGDL

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain

Homologues:

Organism=Homo sapiens, GI24307899, Length=332, Percent_Identity=26.8072289156627, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1788919, Length=294, Percent_Identity=60.2040816326531, Blast_Score=379, Evalue=1e-106,
Organism=Escherichia coli, GI87082120, Length=177, Percent_Identity=29.9435028248588, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17532761, Length=198, Percent_Identity=31.3131313131313, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24646434, Length=311, Percent_Identity=24.4372990353698, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERA_PSE14 (Q48EV4)

Other databases:

- EMBL:   CP000058
- RefSeq:   YP_276083.1
- ProteinModelPortal:   Q48EV4
- SMR:   Q48EV4
- STRING:   Q48EV4
- GeneID:   3560603
- GenomeReviews:   CP000058_GR
- KEGG:   psp:PSPPH_3947
- eggNOG:   COG1159
- HOGENOM:   HBG561652
- OMA:   AKDWQRD
- PhylomeDB:   Q48EV4
- ProtClustDB:   PRK00089
- GO:   GO:0005737
- HAMAP:   MF_00367
- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PRINTS:   PR00326
- TIGRFAMs:   TIGR00436
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1; SSF54814 KH_prok

EC number: NA

Molecular weight: Translated: 33892; Mature: 33892

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTTATRCGYVAIVGRPNVGKSTLLNHILGQKLAITSRKPQTTRHNMLGIKTEGAVQAI
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEECCCCCCCCCCCEEEEECCCCEEEE
YVDTPGMHKNGEKALNRYMNKTASAALKDVDVVIFVVDRTRWTDEDQMVLERVQYVQGPV
EECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCE
ILAINKTDRIEDKSDLMPHLEWLQGQLPNASIVPISAQHGHNLEALESLIASHLPENDHF
EEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCC
FPEDQITDRSSRFLAAELVREKIMRQLGAELPYQITVEIEEFKQQGRTLHIHALILVERD
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCEEEEEEEEEEEEC
GQKKIIIGDKGDRIKRIGSDARRDMELLFDSKVMLNLWVKVKGGWSDDERALRSLGYGDL
CCEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCHHHHHHHHCCCCCC
>Mature Secondary Structure
MNDTTATRCGYVAIVGRPNVGKSTLLNHILGQKLAITSRKPQTTRHNMLGIKTEGAVQAI
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEECCCCCCCCCCCEEEEECCCCEEEE
YVDTPGMHKNGEKALNRYMNKTASAALKDVDVVIFVVDRTRWTDEDQMVLERVQYVQGPV
EECCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCE
ILAINKTDRIEDKSDLMPHLEWLQGQLPNASIVPISAQHGHNLEALESLIASHLPENDHF
EEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCC
FPEDQITDRSSRFLAAELVREKIMRQLGAELPYQITVEIEEFKQQGRTLHIHALILVERD
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHCCCEEEEEEEEEEEEC
GQKKIIIGDKGDRIKRIGSDARRDMELLFDSKVMLNLWVKVKGGWSDDERALRSLGYGDL
CCEEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEEEEEEEEECCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA