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The map label for this gene is yjiA [H]

Identifier: 66047159

GI number: 66047159

Start: 4678015

End: 4679022

Strand: Reverse

Name: yjiA [H]

Synonym: Psyr_3932

Alternate gene names: 66047159

Gene position: 4679022-4678015 (Counterclockwise)

Preceding gene: 66047160

Following gene: 66047158

Centisome position: 76.78

GC content: 62.5

Gene sequence:

>1008_bases
ATGAGCATTGCCCTGAACGTGATTACCGGCTTCCTCGGCAGCGGCAAGACCACGTTGCTCAAACGCCTGCTGGCCGATGA
AAACATGGGCGACACCGCACTGCTGATCAACGAATTCGGCGATGTCGGTATCGATCATCTGCTGGTTGAAGAGGTCGCAC
CGGACACCGTGCTGCTGCCCAGCGGTTGTGTCTGTTGCACCGTTCGCGGTGAATTGAAAGACGCGCTGCTCGGTCTTCTG
GAGCGGCGTAATCGAGGTGAAATTCCTGCGTTCCGCCGGGTGATTCTGGAGACTACCGGCCTGGCCGATCCGGCACCGAT
TCTCACCACGCTGAGCAACGACCCGCAACTGCGCGGGCGTTTTCATATCGGCCTGATCGTCACGCTGGTGGACGCCTGCC
ACGCGACGCTGCAAGAGCGTCTGCATCCGGAGTGGCTGGCGCAGGTCGCGGCGGCGGACCGGCTGCTGTTGAGCAAGACC
GATCTGGTCGACGAGTCGGTGCTGGATGGCCTGCGCGAGCATCTGCAAGCGCTGAATTTTTCGGCGCCGCTGCTGGATAC
AGCGGACGTCCACAGCGGCGATCAGTTGCTGCTGGGCGAGGGCATGCGCAGCGACGAACCGGCCGCTGAAGTGACGCGCT
GGCAACTGCACCGGGTACTGTCGACCTCCGCGCGGCATGGTGATGCGCAAGTCTGTTGCCTGACGTTCGAGCGCCCTCTG
GACTGGGTCGGCTTCGGGGTGTGGCTGTCGATGCTGTTAAGATGCCACGGTGAACGAATCCTCCGCGTCAAAGGGCTGCT
CAACGTGAACGACAATCAGGCTCCCATCGTGATTCATGGTGTGCAGCATTGCCTGCATGCGCCGGTGCACCTTGCCGCCT
GGCCGGGCGAGGATCGCACCTCACGGCTGGTGTTCATCCTGCGCGGTCTCGATCCCGATCTGCTGCGTCGTTCGTTTGAA
GTCTTCTCCGGCAGTTTCGCGCCGCCGCTCGGCGAGTCGTCAGCATGA

Upstream 100 bases:

>100_bases
CGACCGGGCTGGAGCAGCTCTGGCAGAAAGCCGAATTGCTGATCGGCCGGCCGCTGGATCCGCTTGATTCACGTCTGCTC
GATCATTTGCAGAGGTCATC

Downstream 100 bases:

>100_bases
CCATCACCTTGCGTGTGCTGGGCACCTCCGTGACCCTGCTGGAGTCTTTGCGTGAGCGGGCCGAGCAGGAACTGGGGATC
AAGCTGGTCTACCAGATTCA

Product: cobalamin synthesis protein/P47K:cobalamin synthesis protein/P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MSIALNVITGFLGSGKTTLLKRLLADENMGDTALLINEFGDVGIDHLLVEEVAPDTVLLPSGCVCCTVRGELKDALLGLL
ERRNRGEIPAFRRVILETTGLADPAPILTTLSNDPQLRGRFHIGLIVTLVDACHATLQERLHPEWLAQVAAADRLLLSKT
DLVDESVLDGLREHLQALNFSAPLLDTADVHSGDQLLLGEGMRSDEPAAEVTRWQLHRVLSTSARHGDAQVCCLTFERPL
DWVGFGVWLSMLLRCHGERILRVKGLLNVNDNQAPIVIHGVQHCLHAPVHLAAWPGEDRTSRLVFILRGLDPDLLRRSFE
VFSGSFAPPLGESSA

Sequences:

>Translated_335_residues
MSIALNVITGFLGSGKTTLLKRLLADENMGDTALLINEFGDVGIDHLLVEEVAPDTVLLPSGCVCCTVRGELKDALLGLL
ERRNRGEIPAFRRVILETTGLADPAPILTTLSNDPQLRGRFHIGLIVTLVDACHATLQERLHPEWLAQVAAADRLLLSKT
DLVDESVLDGLREHLQALNFSAPLLDTADVHSGDQLLLGEGMRSDEPAAEVTRWQLHRVLSTSARHGDAQVCCLTFERPL
DWVGFGVWLSMLLRCHGERILRVKGLLNVNDNQAPIVIHGVQHCLHAPVHLAAWPGEDRTSRLVFILRGLDPDLLRRSFE
VFSGSFAPPLGESSA
>Mature_334_residues
SIALNVITGFLGSGKTTLLKRLLADENMGDTALLINEFGDVGIDHLLVEEVAPDTVLLPSGCVCCTVRGELKDALLGLLE
RRNRGEIPAFRRVILETTGLADPAPILTTLSNDPQLRGRFHIGLIVTLVDACHATLQERLHPEWLAQVAAADRLLLSKTD
LVDESVLDGLREHLQALNFSAPLLDTADVHSGDQLLLGEGMRSDEPAAEVTRWQLHRVLSTSARHGDAQVCCLTFERPLD
WVGFGVWLSMLLRCHGERILRVKGLLNVNDNQAPIVIHGVQHCLHAPVHLAAWPGEDRTSRLVFILRGLDPDLLRRSFEV
FSGSFAPPLGESSA

Specific function: Binds GTP. May function as GTP-dependent regulator [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=350, Percent_Identity=28.5714285714286, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI33469141, Length=350, Percent_Identity=28.5714285714286, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI223941779, Length=340, Percent_Identity=28.5294117647059, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI148727351, Length=350, Percent_Identity=28.5714285714286, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI146231952, Length=350, Percent_Identity=28.5714285714286, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI223941776, Length=339, Percent_Identity=27.7286135693215, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI119120938, Length=335, Percent_Identity=25.3731343283582, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI87082430, Length=324, Percent_Identity=32.0987654320988, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788499, Length=162, Percent_Identity=36.4197530864198, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324356, Length=368, Percent_Identity=25.5434782608696, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 36669; Mature: 36538

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIALNVITGFLGSGKTTLLKRLLADENMGDTALLINEFGDVGIDHLLVEEVAPDTVLLP
CEEEHEEHHHHCCCCHHHHHHHHHHCCCCCCCEEEEHHHCCCCHHHHHHHHCCCCEEECC
SGCVCCTVRGELKDALLGLLERRNRGEIPAFRRVILETTGLADPAPILTTLSNDPQLRGR
CCCEEEEECHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHEECCCCCCCCCE
FHIGLIVTLVDACHATLQERLHPEWLAQVAAADRLLLSKTDLVDESVLDGLREHLQALNF
EEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SAPLLDTADVHSGDQLLLGEGMRSDEPAAEVTRWQLHRVLSTSARHGDAQVCCLTFERPL
CCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCH
DWVGFGVWLSMLLRCHGERILRVKGLLNVNDNQAPIVIHGVQHCLHAPVHLAAWPGEDRT
HHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEHHHHHHHCCCEEEEECCCCCCC
SRLVFILRGLDPDLLRRSFEVFSGSFAPPLGESSA
CEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SIALNVITGFLGSGKTTLLKRLLADENMGDTALLINEFGDVGIDHLLVEEVAPDTVLLP
EEEHEEHHHHCCCCHHHHHHHHHHCCCCCCCEEEEHHHCCCCHHHHHHHHCCCCEEECC
SGCVCCTVRGELKDALLGLLERRNRGEIPAFRRVILETTGLADPAPILTTLSNDPQLRGR
CCCEEEEECHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHEECCCCCCCCCE
FHIGLIVTLVDACHATLQERLHPEWLAQVAAADRLLLSKTDLVDESVLDGLREHLQALNF
EEHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SAPLLDTADVHSGDQLLLGEGMRSDEPAAEVTRWQLHRVLSTSARHGDAQVCCLTFERPL
CCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCH
DWVGFGVWLSMLLRCHGERILRVKGLLNVNDNQAPIVIHGVQHCLHAPVHLAAWPGEDRT
HHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCEEEHHHHHHHCCCEEEEECCCCCCC
SRLVFILRGLDPDLLRRSFEVFSGSFAPPLGESSA
CEEEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 1650347 [H]