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The map label for this gene is dctD [H]

Identifier: 66047140

GI number: 66047140

Start: 4656319

End: 4657647

Strand: Direct

Name: dctD [H]

Synonym: Psyr_3913

Alternate gene names: 66047140

Gene position: 4656319-4657647 (Clockwise)

Preceding gene: 66047139

Following gene: 66047144

Centisome position: 76.41

GC content: 60.5

Gene sequence:

>1329_bases
ATGAGCATAAACAGCGACCTGACCGTCCTGATCGTCGAAGACGATCCGCATGTATTGCTCGGCTGCCAGCAGGCCCTCGC
GCTGGAAGACATCGCCAGCGAGGGCGTTTCGAGCGCCGAAGAGGCCTTGAAACGTATTGATGACAACTTCGCCGGTATCG
TCATCAGCGATATTCGCTTGCCGGGTATCGACGGGCTGGAGTTGCTGAGCCGTCTCAAGGCACGTGACAGCAGCCTGCCG
GTGGTGCTCATCACCGGCCATGGCGACATCACCATGGCCGTCAACGCAATGCGCGATGGCGCTTACGATTTCATGGAGAA
ACCCTTTTCGCCTGAGCGTCTGGTCGACGTCACCCGGCGCGCACTGGAGCAACGCGGCCTGGCCCGTGAAGTGTGGGCCT
TGCGCAAGCAACTGGCCGAACGCGATTCGCTGGAAGGCCGGATCATCGGCCGCTCCCCGGCCATGCAAAACCTGCGTGCG
TTGATTGCCAACGTCGCCGACACCTCGGCCAACGTACTGATCGAAGGTGAAACCGGCACGGGCAAGGAACTGGTCGCGCG
CTGCCTGCACGATTTCAGTCGGCGCAAGGACAGCCAGTTCGTGGCGCTCAACTGTGGCGGGCTGGCGGAAAGCCTGTTCG
AGTCGGAAATCTTCGGCCATGAAGCCAACGCCTTTACCGGCGCGGGCAAGCGGCGCATCGGCAAGATCGAACACGCGCAC
AACGGCACGCTGTTTCTCGATGAAGTGGAAAGCATGCCGGTCAATCTGCAGATCAAGCTGCTGCGCGTCCTGCAGGAGCG
AACCCTCGAGCGGCTGGGTTCCAACCAGAGCGTCGCCGTGGATTGCCGGGTCATAGCGGCGACCAAATCCGATTTGAATG
CCTTGGGCAAAACCAATCAGTTCCGCAGCGATCTGTATTACCGCCTCAACGTCGTCACGCTTGAACTGCCACCCTTGCGT
GAGCGCCGCGAAGACATTCTGCAGTTGTTCGAACACTTCCTGCAGTTGTCGTCGTTACGCTTCGACCGCGAACCGCCCGT
GCTGGATCGGCAAACCAGCTCGAACCTGATGAGCCATGACTGGCCGGGCAATGTACGCGAACTGCGCAACGTGGCCGAGC
GGTTTGCCCTGGGTCTGCCAGCGTTCAAGCAGTCAGGCACGGTCAGTGAAAACCAGAGTCTGGGGTTTGCCGAAGCGGTC
GAAGCCTTCGAACGCTCATTGCTCGGCGACGCCTTGCAACGCAGCGGCGGTAACCTCAGCCAGGCCAGTCAGGAACTGGG
CATGGCCAAGACCACACTGTTCGACAAGGTCAAGAAATACGGGCTTTGA

Upstream 100 bases:

>100_bases
AGCGCAGAGCATCCGCAGGACGGCGGTACGACGTTTGTCCTGAGCCTGCCGTTCATCCCCGATGCCCGCCACCCGGACAG
CCCGACATGAGACGACACCC

Downstream 100 bases:

>100_bases
GCACTGCGCCCGATCTGGAGCACGCGGCGTAGCGCAGATCTGTGACGCAGAGCGTCACCCACTGCACTCCCACGCTGGAG
CGTGAGGAACGATAGGCGTT

Product: helix-turn-helix, Fis-type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MSINSDLTVLIVEDDPHVLLGCQQALALEDIASEGVSSAEEALKRIDDNFAGIVISDIRLPGIDGLELLSRLKARDSSLP
VVLITGHGDITMAVNAMRDGAYDFMEKPFSPERLVDVTRRALEQRGLAREVWALRKQLAERDSLEGRIIGRSPAMQNLRA
LIANVADTSANVLIEGETGTGKELVARCLHDFSRRKDSQFVALNCGGLAESLFESEIFGHEANAFTGAGKRRIGKIEHAH
NGTLFLDEVESMPVNLQIKLLRVLQERTLERLGSNQSVAVDCRVIAATKSDLNALGKTNQFRSDLYYRLNVVTLELPPLR
ERREDILQLFEHFLQLSSLRFDREPPVLDRQTSSNLMSHDWPGNVRELRNVAERFALGLPAFKQSGTVSENQSLGFAEAV
EAFERSLLGDALQRSGGNLSQASQELGMAKTTLFDKVKKYGL

Sequences:

>Translated_442_residues
MSINSDLTVLIVEDDPHVLLGCQQALALEDIASEGVSSAEEALKRIDDNFAGIVISDIRLPGIDGLELLSRLKARDSSLP
VVLITGHGDITMAVNAMRDGAYDFMEKPFSPERLVDVTRRALEQRGLAREVWALRKQLAERDSLEGRIIGRSPAMQNLRA
LIANVADTSANVLIEGETGTGKELVARCLHDFSRRKDSQFVALNCGGLAESLFESEIFGHEANAFTGAGKRRIGKIEHAH
NGTLFLDEVESMPVNLQIKLLRVLQERTLERLGSNQSVAVDCRVIAATKSDLNALGKTNQFRSDLYYRLNVVTLELPPLR
ERREDILQLFEHFLQLSSLRFDREPPVLDRQTSSNLMSHDWPGNVRELRNVAERFALGLPAFKQSGTVSENQSLGFAEAV
EAFERSLLGDALQRSGGNLSQASQELGMAKTTLFDKVKKYGL
>Mature_441_residues
SINSDLTVLIVEDDPHVLLGCQQALALEDIASEGVSSAEEALKRIDDNFAGIVISDIRLPGIDGLELLSRLKARDSSLPV
VLITGHGDITMAVNAMRDGAYDFMEKPFSPERLVDVTRRALEQRGLAREVWALRKQLAERDSLEGRIIGRSPAMQNLRAL
IANVADTSANVLIEGETGTGKELVARCLHDFSRRKDSQFVALNCGGLAESLFESEIFGHEANAFTGAGKRRIGKIEHAHN
GTLFLDEVESMPVNLQIKLLRVLQERTLERLGSNQSVAVDCRVIAATKSDLNALGKTNQFRSDLYYRLNVVTLELPPLRE
RREDILQLFEHFLQLSSLRFDREPPVLDRQTSSNLMSHDWPGNVRELRNVAERFALGLPAFKQSGTVSENQSLGFAEAVE
AFERSLLGDALQRSGGNLSQASQELGMAKTTLFDKVKKYGL

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=451, Percent_Identity=39.2461197339246, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI1790437, Length=446, Percent_Identity=38.3408071748879, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI1790299, Length=472, Percent_Identity=37.2881355932203, Blast_Score=297, Evalue=8e-82,
Organism=Escherichia coli, GI1788905, Length=446, Percent_Identity=37.8923766816144, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1789087, Length=359, Percent_Identity=42.3398328690808, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI87082117, Length=342, Percent_Identity=41.812865497076, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1786524, Length=325, Percent_Identity=43.0769230769231, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1789233, Length=320, Percent_Identity=37.8125, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI87082152, Length=320, Percent_Identity=40.3125, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI87081872, Length=215, Percent_Identity=46.046511627907, Blast_Score=189, Evalue=4e-49,
Organism=Escherichia coli, GI1787583, Length=314, Percent_Identity=36.9426751592357, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI87081858, Length=294, Percent_Identity=34.0136054421769, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1789828, Length=264, Percent_Identity=35.6060606060606, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1790552, Length=108, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 48892; Mature: 48761

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINSDLTVLIVEDDPHVLLGCQQALALEDIASEGVSSAEEALKRIDDNFAGIVISDIRL
CCCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEECCCC
PGIDGLELLSRLKARDSSLPVVLITGHGDITMAVNAMRDGAYDFMEKPFSPERLVDVTRR
CCCCHHHHHHHHHHCCCCCCEEEEECCCCEEEEEHHHHCCHHHHHHCCCCHHHHHHHHHH
ALEQRGLAREVWALRKQLAERDSLEGRIIGRSPAMQNLRALIANVADTSANVLIEGETGT
HHHHCCHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCCC
GKELVARCLHDFSRRKDSQFVALNCGGLAESLFESEIFGHEANAFTGAGKRRIGKIEHAH
CHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCC
NGTLFLDEVESMPVNLQIKLLRVLQERTLERLGSNQSVAVDCRVIAATKSDLNALGKTNQ
CCCEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECHHHHHHHCCCHH
FRSDLYYRLNVVTLELPPLRERREDILQLFEHFLQLSSLRFDREPPVLDRQTSSNLMSHD
HHHHHEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
WPGNVRELRNVAERFALGLPAFKQSGTVSENQSLGFAEAVEAFERSLLGDALQRSGGNLS
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
QASQELGMAKTTLFDKVKKYGL
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SINSDLTVLIVEDDPHVLLGCQQALALEDIASEGVSSAEEALKRIDDNFAGIVISDIRL
CCCCCEEEEEECCCCCEEEHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEECCCC
PGIDGLELLSRLKARDSSLPVVLITGHGDITMAVNAMRDGAYDFMEKPFSPERLVDVTRR
CCCCHHHHHHHHHHCCCCCCEEEEECCCCEEEEEHHHHCCHHHHHHCCCCHHHHHHHHHH
ALEQRGLAREVWALRKQLAERDSLEGRIIGRSPAMQNLRALIANVADTSANVLIEGETGT
HHHHCCHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCCC
GKELVARCLHDFSRRKDSQFVALNCGGLAESLFESEIFGHEANAFTGAGKRRIGKIEHAH
CHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCC
NGTLFLDEVESMPVNLQIKLLRVLQERTLERLGSNQSVAVDCRVIAATKSDLNALGKTNQ
CCCEEEEHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECHHHHHHHCCCHH
FRSDLYYRLNVVTLELPPLRERREDILQLFEHFLQLSSLRFDREPPVLDRQTSSNLMSHD
HHHHHEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
WPGNVRELRNVAERFALGLPAFKQSGTVSENQSLGFAEAVEAFERSLLGDALQRSGGNLS
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHH
QASQELGMAKTTLFDKVKKYGL
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]