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The map label for this gene is glpR [H]

Identifier: 66047133

GI number: 66047133

Start: 4647542

End: 4648297

Strand: Direct

Name: glpR [H]

Synonym: Psyr_3906

Alternate gene names: 66047133

Gene position: 4647542-4648297 (Clockwise)

Preceding gene: 66047132

Following gene: 66047134

Centisome position: 76.27

GC content: 58.47

Gene sequence:

>756_bases
ATGAACCTGCCTCCCCGCCAACAACAGATCCTCGAACTGGTCCGTGACCGTGGTTATGTCAGCATCGAGGAGATGGCGAC
GCTGTTCGTCGTGACCCCACAAACCATTCGCCGTGATATCAATCAATTGGCGGAAATGAACCTGTTGCGCCGCTACCACG
GCGGCGCGGCCTATGACTCAAGCATCGAAAATACCGCCTACGCCATGCGTGCGGACCAGATGCGCGACGAAAAACAACGG
ATCGCCGAGGCCATCGCCGCGCAGATCCCGGACAACGCCTCGTTGTTCATCAATATCGGTACCACCACCGAATCCATCGC
ACGTGCGTTGCTCAACCACAACAACCTGAAGATCATCACCAATAACCTGCATGTGGCGTCGATCCTCAGCACCAAGGATG
ATTTCGAGGTGCTGATAGCAGGCGGCAATGTGCGACGTGACGGCGGCGTTGTGGGCCAGGGCAGCATCGACTTCATCACC
CAGTTCAAAGTGGACTTCGCCCTGGTGGGCATCAGTGGCATCGACGAAGACGGCAGCCTGCTGGATTTCGATTACCAGGA
AGTGCGGGTGTCCCAGGCGATCATCGCCAACGCTCGCAAAGTGCTGCTGGCGGCTGATTCCAGCAAGTTCGGACGCAACG
CCATGGTCCGCTTGGGGCCGATCACCCTCATCGATTGCCTGGTCACCGACCAGCCACCGGTGCCCGCACTGCAGCAACTG
CTGACCCAGCACAAGATTCGTCTGGAAGTGGTGTGA

Upstream 100 bases:

>100_bases
ACAGTGCTGTTGTAAGGAGGGGAGCAGGATTCCGGCTGACAGGTTGCACTTTCCTGCGGCATGATGGGCGCCATTTGTAG
AGGGCGCCCAAGGAAAAACA

Downstream 100 bases:

>100_bases
TTGTCAGGCGCGAGCGGTGTTCGCGCGGCGGTCCGCAGTGCTCATGAAGACGGTGCATCGAGCGCCCCATTTTCTGGAGT
CTGTACCGGCCTCTTCGCGA

Product: regulatory protein, DeoR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MNLPPRQQQILELVRDRGYVSIEEMATLFVVTPQTIRRDINQLAEMNLLRRYHGGAAYDSSIENTAYAMRADQMRDEKQR
IAEAIAAQIPDNASLFINIGTTTESIARALLNHNNLKIITNNLHVASILSTKDDFEVLIAGGNVRRDGGVVGQGSIDFIT
QFKVDFALVGISGIDEDGSLLDFDYQEVRVSQAIIANARKVLLAADSSKFGRNAMVRLGPITLIDCLVTDQPPVPALQQL
LTQHKIRLEVV

Sequences:

>Translated_251_residues
MNLPPRQQQILELVRDRGYVSIEEMATLFVVTPQTIRRDINQLAEMNLLRRYHGGAAYDSSIENTAYAMRADQMRDEKQR
IAEAIAAQIPDNASLFINIGTTTESIARALLNHNNLKIITNNLHVASILSTKDDFEVLIAGGNVRRDGGVVGQGSIDFIT
QFKVDFALVGISGIDEDGSLLDFDYQEVRVSQAIIANARKVLLAADSSKFGRNAMVRLGPITLIDCLVTDQPPVPALQQL
LTQHKIRLEVV
>Mature_251_residues
MNLPPRQQQILELVRDRGYVSIEEMATLFVVTPQTIRRDINQLAEMNLLRRYHGGAAYDSSIENTAYAMRADQMRDEKQR
IAEAIAAQIPDNASLFINIGTTTESIARALLNHNNLKIITNNLHVASILSTKDDFEVLIAGGNVRRDGGVVGQGSIDFIT
QFKVDFALVGISGIDEDGSLLDFDYQEVRVSQAIIANARKVLLAADSSKFGRNAMVRLGPITLIDCLVTDQPPVPALQQL
LTQHKIRLEVV

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=252, Percent_Identity=54.7619047619048, Blast_Score=296, Evalue=7e-82,
Organism=Escherichia coli, GI87082344, Length=245, Percent_Identity=43.265306122449, Blast_Score=220, Evalue=7e-59,
Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=31.8548387096774, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1788069, Length=236, Percent_Identity=27.1186440677966, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789519, Length=245, Percent_Identity=25.7142857142857, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787540, Length=250, Percent_Identity=27.6, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI226510968, Length=233, Percent_Identity=27.8969957081545, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789170, Length=233, Percent_Identity=24.8927038626609, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1790635, Length=243, Percent_Identity=28.8065843621399, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1790753, Length=234, Percent_Identity=26.0683760683761, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787063, Length=231, Percent_Identity=26.4069264069264, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27754; Mature: 27754

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPPRQQQILELVRDRGYVSIEEMATLFVVTPQTIRRDINQLAEMNLLRRYHGGAAYDS
CCCCHHHHHHHHHHHCCCCEEHHHHEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SIENTAYAMRADQMRDEKQRIAEAIAAQIPDNASLFINIGTTTESIARALLNHNNLKIIT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEE
NNLHVASILSTKDDFEVLIAGGNVRRDGGVVGQGSIDFITQFKVDFALVGISGIDEDGSL
CCEEEEEEECCCCCEEEEEECCCEECCCCEECCCCHHEEEEEEEEEEEEEECCCCCCCCE
LDFDYQEVRVSQAIIANARKVLLAADSSKFGRNAMVRLGPITLIDCLVTDQPPVPALQQL
EECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCEEEEEEECCCCCHHHHHHH
LTQHKIRLEVV
HHHCCEEEEEC
>Mature Secondary Structure
MNLPPRQQQILELVRDRGYVSIEEMATLFVVTPQTIRRDINQLAEMNLLRRYHGGAAYDS
CCCCHHHHHHHHHHHCCCCEEHHHHEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SIENTAYAMRADQMRDEKQRIAEAIAAQIPDNASLFINIGTTTESIARALLNHNNLKIIT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEE
NNLHVASILSTKDDFEVLIAGGNVRRDGGVVGQGSIDFITQFKVDFALVGISGIDEDGSL
CCEEEEEEECCCCCEEEEEECCCEECCCCEECCCCHHEEEEEEEEEEEEEECCCCCCCCE
LDFDYQEVRVSQAIIANARKVLLAADSSKFGRNAMVRLGPITLIDCLVTDQPPVPALQQL
EECCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEECCCEEEEEEECCCCCHHHHHHH
LTQHKIRLEVV
HHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]