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The map label for this gene is cobT [H]

Identifier: 66046903

GI number: 66046903

Start: 4360408

End: 4361460

Strand: Reverse

Name: cobT [H]

Synonym: Psyr_3674

Alternate gene names: 66046903

Gene position: 4361460-4360408 (Counterclockwise)

Preceding gene: 66046904

Following gene: 66046902

Centisome position: 71.57

GC content: 66.29

Gene sequence:

>1053_bases
ATGAGTAATTCCTGGTGGCTCAAGCCTGCACAGGCTATTGATGTGCCGATGCGCGAGGCGGCACTGGCCCGTCAGCAGCA
ACTGACCAAACCCGCCGGATCACTGGCGCAACTGGAGCGCCTGGCGGTGCAACTGGCCGGTCTGCAGGGACGTGAGCGTC
CGGCCGTCGATCAACTGTGGATCGCGATTTTTGCCGCTGATCATGGGGTCGTCGCAGAGGGCGTGTCGGCGTACCCACAG
GAAGTCACCGGGCAGATGCTGCACAACTTCGTCAATGGCGGCGCCGCGATCAGCGTGCTGGCGCGTCAGCTCTCCGCACA
ACTGGACGTGGTCGATCTGGGCACCGTGTCGCCAATGGACCTGCCCGGGGTGCGCCATCTGCGCATTGGCGCGGGCACCG
CCAATTTTGCCCATGGGCCGGCCATGAGTGTCGAGCAGGGACTCGCCGCCCTGCAGGCCGGGCGTGACAGCGTATTGCGC
GCCAAGGCTGTCGGCACTGAACTGTTCATCGGTGGCGAGATGGGCATCGGCAACACCACAGCCGCCAGCGCAGTCGCCTG
CTCGCTGCTGGAGTGCGCCGCGCCATTGCTGGTCGGGCCGGGCACCGGGCTGAACGCCGAGGGTATTCAGCACAAGACGC
GCGTCATTGAGCGCGCACTGGCCTTGCACGCCGAGCAGGCCGGTGACCCGTTAAACAGCCTGTTCTGCCTGGGCGGCTTC
GAAATCGCCGCACTGGCCGGTGCGTACCTGGCCTGCGCGCAGGAAGGAATTGCGGTACTGGTCGACGGTTTCATTTGCAG
CGTGGCCGCGCTGGTGGCGGTACGCCTGAACCCTTCCTGCCGCAACTGGCTGCTGTTCGGTCATCGGGGCGCCGAACCGG
GCCATCGGCATCTGCTGGAAACGCTGCAGGCCGAACCGTTGCTGGACCTCGGTTTGCGTCTGGGCGAGGGCAGTGGTGCC
GCACTGGCAGTACCGCTGGTGCGCCTGGCGTGCGAGCTGCACAACGGCATGGCGACATTTGCCGAAGCGGCTGTGGCGGA
CCGCCCCGCATGA

Upstream 100 bases:

>100_bases
TCGATGAAGCCGGCCTGTTGCATCAGGCGCTGGCCGAGCGTTGCCAGCGTGTCGTGTTGACCGTTGCCGGCTTGCCCCTG
ACGTTGAAAGGAACCGCGCT

Downstream 100 bases:

>100_bases
CCTTGCACCTGGACTTGTTGCGTCACGGCGAAACCGAACGGGGCGGCGGCCTGCGCGGCAGCATCGACGACGCCCTGACC
GAGCCTGGCTGGCAGCAGAT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSNSWWLKPAQAIDVPMREAALARQQQLTKPAGSLAQLERLAVQLAGLQGRERPAVDQLWIAIFAADHGVVAEGVSAYPQ
EVTGQMLHNFVNGGAAISVLARQLSAQLDVVDLGTVSPMDLPGVRHLRIGAGTANFAHGPAMSVEQGLAALQAGRDSVLR
AKAVGTELFIGGEMGIGNTTAASAVACSLLECAAPLLVGPGTGLNAEGIQHKTRVIERALALHAEQAGDPLNSLFCLGGF
EIAALAGAYLACAQEGIAVLVDGFICSVAALVAVRLNPSCRNWLLFGHRGAEPGHRHLLETLQAEPLLDLGLRLGEGSGA
ALAVPLVRLACELHNGMATFAEAAVADRPA

Sequences:

>Translated_350_residues
MSNSWWLKPAQAIDVPMREAALARQQQLTKPAGSLAQLERLAVQLAGLQGRERPAVDQLWIAIFAADHGVVAEGVSAYPQ
EVTGQMLHNFVNGGAAISVLARQLSAQLDVVDLGTVSPMDLPGVRHLRIGAGTANFAHGPAMSVEQGLAALQAGRDSVLR
AKAVGTELFIGGEMGIGNTTAASAVACSLLECAAPLLVGPGTGLNAEGIQHKTRVIERALALHAEQAGDPLNSLFCLGGF
EIAALAGAYLACAQEGIAVLVDGFICSVAALVAVRLNPSCRNWLLFGHRGAEPGHRHLLETLQAEPLLDLGLRLGEGSGA
ALAVPLVRLACELHNGMATFAEAAVADRPA
>Mature_349_residues
SNSWWLKPAQAIDVPMREAALARQQQLTKPAGSLAQLERLAVQLAGLQGRERPAVDQLWIAIFAADHGVVAEGVSAYPQE
VTGQMLHNFVNGGAAISVLARQLSAQLDVVDLGTVSPMDLPGVRHLRIGAGTANFAHGPAMSVEQGLAALQAGRDSVLRA
KAVGTELFIGGEMGIGNTTAASAVACSLLECAAPLLVGPGTGLNAEGIQHKTRVIERALALHAEQAGDPLNSLFCLGGFE
IAALAGAYLACAQEGIAVLVDGFICSVAALVAVRLNPSCRNWLLFGHRGAEPGHRHLLETLQAEPLLDLGLRLGEGSGAA
LAVPLVRLACELHNGMATFAEAAVADRPA

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=337, Percent_Identity=36.4985163204748, Blast_Score=200, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 36257; Mature: 36126

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSWWLKPAQAIDVPMREAALARQQQLTKPAGSLAQLERLAVQLAGLQGRERPAVDQLW
CCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHH
IAIFAADHGVVAEGVSAYPQEVTGQMLHNFVNGGAAISVLARQLSAQLDVVDLGTVSPMD
HHHHCCCCCHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCCCC
LPGVRHLRIGAGTANFAHGPAMSVEQGLAALQAGRDSVLRAKAVGTELFIGGEMGIGNTT
CCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHCCCEEEECCCCCCCCCH
AASAVACSLLECAAPLLVGPGTGLNAEGIQHKTRVIERALALHAEQAGDPLNSLFCLGGF
HHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCH
EIAALAGAYLACAQEGIAVLVDGFICSVAALVAVRLNPSCRNWLLFGHRGAEPGHRHLLE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHH
TLQAEPLLDLGLRLGEGSGAALAVPLVRLACELHNGMATFAEAAVADRPA
HHCCCCHHHHHCEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC
>Mature Secondary Structure 
SNSWWLKPAQAIDVPMREAALARQQQLTKPAGSLAQLERLAVQLAGLQGRERPAVDQLW
CCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHH
IAIFAADHGVVAEGVSAYPQEVTGQMLHNFVNGGAAISVLARQLSAQLDVVDLGTVSPMD
HHHHCCCCCHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCCCC
LPGVRHLRIGAGTANFAHGPAMSVEQGLAALQAGRDSVLRAKAVGTELFIGGEMGIGNTT
CCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHCCCEEEECCCCCCCCCH
AASAVACSLLECAAPLLVGPGTGLNAEGIQHKTRVIERALALHAEQAGDPLNSLFCLGGF
HHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCH
EIAALAGAYLACAQEGIAVLVDGFICSVAALVAVRLNPSCRNWLLFGHRGAEPGHRHLLE
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCHHHHHHHH
TLQAEPLLDLGLRLGEGSGAALAVPLVRLACELHNGMATFAEAAVADRPA
HHCCCCHHHHHCEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA