Click here to switch to the map view.

The map label for this gene is cobC [H]

Identifier: 66046902

GI number: 66046902

Start: 4359839

End: 4360411

Strand: Reverse

Name: cobC [H]

Synonym: Psyr_3673

Alternate gene names: 66046902

Gene position: 4360411-4359839 (Counterclockwise)

Preceding gene: 66046903

Following gene: 66046901

Centisome position: 71.56

GC content: 64.05

Gene sequence:

>573_bases
ATGACCTTGCACCTGGACTTGTTGCGTCACGGCGAAACCGAACGGGGCGGCGGCCTGCGCGGCAGCATCGACGACGCCCT
GACCGAGCCTGGCTGGCAGCAGATGCGTGCGGCAGTGGCTGGTGGCGGACCGTGGACGCGGATTGTCAGCTCGCCGCTGC
AACGTTGCGCACGTTTCTCCGAAGAGCTGGCGCAGCGCTTGTCGTTGCCCCTGCACCTGGAGCCCGGTTTGCAGGAGCTG
CATTTCGGCGACTGGGAAGGGCACAGCCCTGCGCAACTCATGGAAACCGATGCTGAGGGCCTGGGTCTGTTCTGGGCGGA
TCCTTATGCCTTCACACCTCCCAATGGCGAGCCGGTAGTGGATTTCTCGAACCGGGTATTGAGTGCCGTTGAGCGTCTGC
ATCAGGCTTATGCCGGTGAGCGCGTGTTGCTGGTCAGTCATGGCGGTGTCATGCGCCTGCTGTTGGCGCAGGCGCGTGGC
CTGCCGCGTGAGCAACTGTTGCAGGTGGTGGTCGGGCATGGCGCGCTGTTGTCGATTCAGGTCGCTGCTGATCGCGTACT
CACGGAGGTCTGA

Upstream 100 bases:

>100_bases
GCAGTGGTGCCGCACTGGCAGTACCGCTGGTGCGCCTGGCGTGCGAGCTGCACAACGGCATGGCGACATTTGCCGAAGCG
GCTGTGGCGGACCGCCCCGC

Downstream 100 bases:

>100_bases
GATGCTGCCGTTCTGGATCGCCCTGCAATTTCTCGGCAGCCTGCCGATCAGGCTGCCCGGCATGCCGAGCCCCGAGGAGC
TGGGGCGTTCCTTGCTGTTT

Product: phosphoglycerate/bisphosphoglycerate mutase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MTLHLDLLRHGETERGGGLRGSIDDALTEPGWQQMRAAVAGGGPWTRIVSSPLQRCARFSEELAQRLSLPLHLEPGLQEL
HFGDWEGHSPAQLMETDAEGLGLFWADPYAFTPPNGEPVVDFSNRVLSAVERLHQAYAGERVLLVSHGGVMRLLLAQARG
LPREQLLQVVVGHGALLSIQVAADRVLTEV

Sequences:

>Translated_190_residues
MTLHLDLLRHGETERGGGLRGSIDDALTEPGWQQMRAAVAGGGPWTRIVSSPLQRCARFSEELAQRLSLPLHLEPGLQEL
HFGDWEGHSPAQLMETDAEGLGLFWADPYAFTPPNGEPVVDFSNRVLSAVERLHQAYAGERVLLVSHGGVMRLLLAQARG
LPREQLLQVVVGHGALLSIQVAADRVLTEV
>Mature_189_residues
TLHLDLLRHGETERGGGLRGSIDDALTEPGWQQMRAAVAGGGPWTRIVSSPLQRCARFSEELAQRLSLPLHLEPGLQELH
FGDWEGHSPAQLMETDAEGLGLFWADPYAFTPPNGEPVVDFSNRVLSAVERLHQAYAGERVLLVSHGGVMRLLLAQARGL
PREQLLQVVVGHGALLSIQVAADRVLTEV

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=183, Percent_Identity=31.6939890710383, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 20734; Mature: 20603

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLHLDLLRHGETERGGGLRGSIDDALTEPGWQQMRAAVAGGGPWTRIVSSPLQRCARFS
CEEEEEHHHCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EELAQRLSLPLHLEPGLQELHFGDWEGHSPAQLMETDAEGLGLFWADPYAFTPPNGEPVV
HHHHHHCCCCCEECCCHHHHCCCCCCCCCHHHHHHCCCCCCEEEEECCEEECCCCCCEEE
DFSNRVLSAVERLHQAYAGERVLLVSHGGVMRLLLAQARGLPREQLLQVVVGHGALLSIQ
HHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEH
VAADRVLTEV
HHHHHHHHCC
>Mature Secondary Structure 
TLHLDLLRHGETERGGGLRGSIDDALTEPGWQQMRAAVAGGGPWTRIVSSPLQRCARFS
EEEEEHHHCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
EELAQRLSLPLHLEPGLQELHFGDWEGHSPAQLMETDAEGLGLFWADPYAFTPPNGEPVV
HHHHHHCCCCCEECCCHHHHCCCCCCCCCHHHHHHCCCCCCEEEEECCEEECCCCCCEEE
DFSNRVLSAVERLHQAYAGERVLLVSHGGVMRLLLAQARGLPREQLLQVVVGHGALLSIQ
HHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEH
VAADRVLTEV
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]