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The map label for this gene is bsaA [H]

Identifier: 66046842

GI number: 66046842

Start: 4297779

End: 4298264

Strand: Reverse

Name: bsaA [H]

Synonym: Psyr_3613

Alternate gene names: 66046842

Gene position: 4298264-4297779 (Counterclockwise)

Preceding gene: 66046843

Following gene: 66046840

Centisome position: 70.54

GC content: 59.05

Gene sequence:

>486_bases
ATGAGTGAAAACCTGCTGAGCATCCCGGTCACGACGATCAAGGGCGAACAGAAAACCCTCGCCGATTTCTCCGGCAAGGC
GCTGCTGGTGGTTAACACCGCCAGCCAGTGTGGCTTTACCCCTCAATACAAGGGCCTGGAAAAGCTCTGGCAGGACTATA
GGGATCAGGGCTTGGTGGTGCTGGGTTTCCCCTGTAACCAGTTCGGCAAGCAGGAGCCAGGCGACGAGGGGGCGATTTCC
GGCTTTTGCGAGCTGAACTACGGCGTCAGCTTCCCGTTGTTCAAGAAGATCGATGTGAACGGCGAGCAGGCCCATCCGCT
GTTCGTGCAGCTCAAGCAGCAGGCGCCGGGGTTGTTGGGCACGGAGCGCATCAAGTGGAATTTCACCAAGTTCCTGATTG
GCCAGGACGGTCGGCTGGTCAAGCGTTTTGCGCCATTGACCAAGCCTGAGGAACTGACGGGCGAGATCGAGGCGCTGCTG
CGCTGA

Upstream 100 bases:

>100_bases
TTGCATCAATTCGGTCTGCCTGGATCTGGTGCCACGCAGCTAGACGCTTTGCAGATTCAGCCAACGCCCTGTCCCAATTC
CAGTATCGAGGCCTCCTTTG

Downstream 100 bases:

>100_bases
GTCTTCAGTCGATGCCGGTAATGGGTATCCACTGATCGAGAATGCTGACCAGTTCGGCACGCCGGAACGGCTTGGCCAGA
TAGTCATTCATGCCCGCCGC

Product: glutathione peroxidase

Products: glutathione disulfide; H2O

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSENLLSIPVTTIKGEQKTLADFSGKALLVVNTASQCGFTPQYKGLEKLWQDYRDQGLVVLGFPCNQFGKQEPGDEGAIS
GFCELNYGVSFPLFKKIDVNGEQAHPLFVQLKQQAPGLLGTERIKWNFTKFLIGQDGRLVKRFAPLTKPEELTGEIEALL
R

Sequences:

>Translated_161_residues
MSENLLSIPVTTIKGEQKTLADFSGKALLVVNTASQCGFTPQYKGLEKLWQDYRDQGLVVLGFPCNQFGKQEPGDEGAIS
GFCELNYGVSFPLFKKIDVNGEQAHPLFVQLKQQAPGLLGTERIKWNFTKFLIGQDGRLVKRFAPLTKPEELTGEIEALL
R
>Mature_160_residues
SENLLSIPVTTIKGEQKTLADFSGKALLVVNTASQCGFTPQYKGLEKLWQDYRDQGLVVLGFPCNQFGKQEPGDEGAISG
FCELNYGVSFPLFKKIDVNGEQAHPLFVQLKQQAPGLLGTERIKWNFTKFLIGQDGRLVKRFAPLTKPEELTGEIEALLR

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=160, Percent_Identity=41.25, Blast_Score=122, Evalue=1e-28,
Organism=Homo sapiens, GI75709200, Length=151, Percent_Identity=43.7086092715232, Blast_Score=114, Evalue=4e-26,
Organism=Homo sapiens, GI90903240, Length=151, Percent_Identity=43.7086092715232, Blast_Score=114, Evalue=5e-26,
Organism=Homo sapiens, GI4557629, Length=167, Percent_Identity=41.3173652694611, Blast_Score=107, Evalue=4e-24,
Organism=Homo sapiens, GI192455698, Length=153, Percent_Identity=37.2549019607843, Blast_Score=103, Evalue=5e-23,
Organism=Homo sapiens, GI6006001, Length=186, Percent_Identity=36.5591397849462, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI90903238, Length=133, Percent_Identity=43.609022556391, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI33186887, Length=164, Percent_Identity=39.0243902439024, Blast_Score=93, Evalue=9e-20,
Organism=Homo sapiens, GI41406084, Length=170, Percent_Identity=35.8823529411765, Blast_Score=87, Evalue=6e-18,
Organism=Homo sapiens, GI32967607, Length=185, Percent_Identity=29.7297297297297, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1788003, Length=170, Percent_Identity=43.5294117647059, Blast_Score=154, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17535473, Length=155, Percent_Identity=47.0967741935484, Blast_Score=144, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17506887, Length=152, Percent_Identity=45.3947368421053, Blast_Score=136, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI71993584, Length=150, Percent_Identity=38.6666666666667, Blast_Score=113, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI193210707, Length=161, Percent_Identity=39.7515527950311, Blast_Score=108, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17550320, Length=182, Percent_Identity=31.3186813186813, Blast_Score=96, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI193209493, Length=182, Percent_Identity=30.2197802197802, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71999642, Length=75, Percent_Identity=37.3333333333333, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71993573, Length=87, Percent_Identity=36.7816091954023, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17507603, Length=106, Percent_Identity=34.9056603773585, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=160, Percent_Identity=53.75, Blast_Score=187, Evalue=8e-49,
Organism=Saccharomyces cerevisiae, GI6322228, Length=161, Percent_Identity=51.5527950310559, Blast_Score=174, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6322826, Length=136, Percent_Identity=47.7941176470588, Blast_Score=143, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24656772, Length=164, Percent_Identity=43.2926829268293, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24656767, Length=164, Percent_Identity=43.2926829268293, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24656777, Length=164, Percent_Identity=43.2926829268293, Blast_Score=123, Evalue=4e-29,
Organism=Drosophila melanogaster, GI85726443, Length=160, Percent_Identity=41.875, Blast_Score=110, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: 1.11.1.9

Molecular weight: Translated: 17892; Mature: 17761

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENLLSIPVTTIKGEQKTLADFSGKALLVVNTASQCGFTPQYKGLEKLWQDYRDQGLVV
CCCCEEECEEEEECCCCHHHHCCCCCEEEEEECHHHCCCCCCHHHHHHHHHHHHHCCEEE
LGFPCNQFGKQEPGDEGAISGFCELNYGVSFPLFKKIDVNGEQAHPLFVQLKQQAPGLLG
EECCCHHHCCCCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCHHEEEEHHHCCCCCC
TERIKWNFTKFLIGQDGRLVKRFAPLTKPEELTGEIEALLR
CCEEEEEEEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SENLLSIPVTTIKGEQKTLADFSGKALLVVNTASQCGFTPQYKGLEKLWQDYRDQGLVV
CCCEEECEEEEECCCCHHHHCCCCCEEEEEECHHHCCCCCCHHHHHHHHHHHHHCCEEE
LGFPCNQFGKQEPGDEGAISGFCELNYGVSFPLFKKIDVNGEQAHPLFVQLKQQAPGLLG
EECCCHHHCCCCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCHHEEEEHHHCCCCCC
TERIKWNFTKFLIGQDGRLVKRFAPLTKPEELTGEIEALLR
CCEEEEEEEEEEECCCCCHHHHHCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutathione; H2O2

Specific reaction: 2 glutathione + H2O2 = glutathione disulfide + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]