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The map label for this gene is dorA [H]

Identifier: 66046834

GI number: 66046834

Start: 4287079

End: 4289349

Strand: Reverse

Name: dorA [H]

Synonym: Psyr_3605

Alternate gene names: 66046834

Gene position: 4289349-4287079 (Counterclockwise)

Preceding gene: 66046835

Following gene: 66046829

Centisome position: 70.39

GC content: 62.75

Gene sequence:

>2271_bases
ATGAGTTTCACATCACTGCACTGGGGCGCTTACCGTCCACAGGTCGAGGACGGCAAGCTGACCGGGCTGCTGCCGGCAGA
ATGGGACAAGGACCCGTCTCCGATTGGCGATTCGGTTGCCGAGGCCATTACCTCACCGACCCGCATCAGGCGCCCGGCGA
TACGCCGCAGTTTTCTTCAGCAGGCCGGTGGACGGCCCGATCTGCGTGGTCAGGAGCCGTTCATCGAGGTTTCCTGGGAG
GTCGCGCTGGATCTGGTCGCCAGCGAGTTGCAGCGAGTCCGCCACGAGCATGGCAATCAGGCTATTTTCGGCGGCAGCTA
CGGCTGGGGTAGCGCGGGGCGTTTTCATCACGCGCAAAGCCAGTTGCATCGCTTCCTTAACTGCATTGGCGGCTATGTGT
TCAGCACCGACAGCTACAGCCTGGGTGCCGGGCGGGTGCTGATGCCGCACATCGTCGGCAACATGGACTGGCTGCTGGCG
GCGCATACCTCCTGGAAAAACCTGGCCGAGCATTGCGAGCTGTTCGTCGCGTTCGGTGGCTTGCCCGCCAAGAATGCCCA
GACCAGCCCCGGTGGTGCCAGCGATCATCTGCTGAGCGAGGCGCTGCAACGCATGTCCGACGCGGGCGTGCAGTTTGTCA
ATGTCAGCCCGCTGCGTGACGATCTGGTCGGCCCGACGCATAACCAGTGGCTGGCGGTACGTCCCGGCAGTGATACGGCG
TTGATGATGGCGCTGTCCTGGGTGTTGATCAGCGAAGGGCTGCACAACGAGGATTTCGTCCAGCGCTATACCGTGGGCTA
TGCGCGTTTTCGCGAGTACCTGCTGGGCCACACCGACGGCCAGCCGAAAGACCCGCGCTGGGCCGAGGCGCTGACCGATA
TCCCTGCGCAGCAGATCGTCGAGCTGGCCCGACGCATGGCCAGCAAGCGCACCATGATCAACGTCGCCTATTCATTGCAG
CGTTCTATACACGGCGAGCAACCGTTCTGGATGACCGTGACCCTGGCTGCGCTGTTGGGGCAGATCGGTTTGCCCGGTGC
CGGTTTCGGCCTGGGGTACGGCTGCATGAACAACACCGGCAGTGGCCGCAAGGCGTTCTCGGGGCCGCGCTTTTCCCAGG
GCAGCAACCCGGTCAGGGATTTCATTCCGGTCGCGCGGGTGACGGACATGTTGCTCAACCCCGGTACGCCCTTCGATTAC
AACGGACAGCAGCGCAGGTACCCGGACATTCGCCTGGTGTACTGGGCGGGTGGCAATATCTTTCACCACCATCAGGACCT
CAACCGGCTGCTGGAGGCGTGGCAGCGACCGCAAACGATCATCGTCCACGAGCAGTTCTGGACCGCCCAGGCGCGCTATG
CCGACATCGTGCTGCCGGCCACCACGGCCCTGGAGCGCAACGACATCGGCAGTTCGGCCTCCGACCGTTTCATGATCGCC
ATGCAGCAGGCGATCGAGCCCGTGGGCGAATCGCGTGACGACTACTCGATTCTGGCTGCGCTGGCCGAACGGCTGGGGGT
GGCACAGGCGTTTACCGAAGGTCGGGATGCCAGGGAATGGCTGCACTTTATCTATGACGAGTCTCGGCAACGGGCCGAAA
CGTTTGGCATCACCCTGCCTGATTTCGAGCAGTTCTGGCGTGACGGTGTACTGGAAATAGACTACCCGCACACCGACAAC
GTGTTGCTCGAATCCTTTCGTCATGACCCTGACGCGCATCCGTTGCCGACGCCGTCCGGACGCATCGAAATTTTCTCCGA
GCGCATCGCAGGCTTTGGCTATGCCGATTGTCCCGGTCACCCGGTGTGGCTGGAAAAGCCTGCGCCGACACACGCGCTGC
ACCTGTTGTCCAACCAACCGAAAACCCGTTTGCACAGTCAGTACGACCACGGCAGCTACAGTCGCTCCTCGAAAATTCAG
GCGCGCGAGCCGCTGACCCTTAATCCGCTGGATGCTCGCGCACGCGGGCTGGTCGATGGCGATGTGGTCAAGGTGTTCAA
CGAGCGTGGCGCGTTTCTGGCCGGGGTGATCGTGTCGGACGGCATTCGCCCCGGCGTAGTGCAGATTGCCACCGGTGCCT
GGTTCGACCCGCTGGTGCATGGCGAACGGGGCAGCCTGGAAAAACACGGCAACCCGAATGTGATCACCGAAGATGTGGGC
GCCTCCAGCCTGTCGCAGGGCTGTTCAGCACAGACAGCATCGGTGGACATCGTCAAATGGCATCAGGACCTGCCGCCGGT
GACGGCGTTCGAGCCGCCGTCACTGCTCTGA

Upstream 100 bases:

>100_bases
CCAGTGTGTTTGACGAGTCGTTCAGTGCAGCGCTGGCCGATCAGGCGCAAGCAGTACGCTGACCGACCGCCTGCCACTGC
GCTATCCGGGAGCCTTCACC

Downstream 100 bases:

>100_bases
CGCGTCTTATTGGTCTTTGCTGCGTGCTGCAAACGCCGCCTTGCCCACGTTCACCAGCACCGCATCGTTCTGTGGGGTAT
GCACCCGACCGCACAGGACG

Product: trimethylamine-N-oxide reductase (cytochrome c)

Products: NA

Alternate protein names: DMSO reductase; DMSOR [H]

Number of amino acids: Translated: 756; Mature: 755

Protein sequence:

>756_residues
MSFTSLHWGAYRPQVEDGKLTGLLPAEWDKDPSPIGDSVAEAITSPTRIRRPAIRRSFLQQAGGRPDLRGQEPFIEVSWE
VALDLVASELQRVRHEHGNQAIFGGSYGWGSAGRFHHAQSQLHRFLNCIGGYVFSTDSYSLGAGRVLMPHIVGNMDWLLA
AHTSWKNLAEHCELFVAFGGLPAKNAQTSPGGASDHLLSEALQRMSDAGVQFVNVSPLRDDLVGPTHNQWLAVRPGSDTA
LMMALSWVLISEGLHNEDFVQRYTVGYARFREYLLGHTDGQPKDPRWAEALTDIPAQQIVELARRMASKRTMINVAYSLQ
RSIHGEQPFWMTVTLAALLGQIGLPGAGFGLGYGCMNNTGSGRKAFSGPRFSQGSNPVRDFIPVARVTDMLLNPGTPFDY
NGQQRRYPDIRLVYWAGGNIFHHHQDLNRLLEAWQRPQTIIVHEQFWTAQARYADIVLPATTALERNDIGSSASDRFMIA
MQQAIEPVGESRDDYSILAALAERLGVAQAFTEGRDAREWLHFIYDESRQRAETFGITLPDFEQFWRDGVLEIDYPHTDN
VLLESFRHDPDAHPLPTPSGRIEIFSERIAGFGYADCPGHPVWLEKPAPTHALHLLSNQPKTRLHSQYDHGSYSRSSKIQ
AREPLTLNPLDARARGLVDGDVVKVFNERGAFLAGVIVSDGIRPGVVQIATGAWFDPLVHGERGSLEKHGNPNVITEDVG
ASSLSQGCSAQTASVDIVKWHQDLPPVTAFEPPSLL

Sequences:

>Translated_756_residues
MSFTSLHWGAYRPQVEDGKLTGLLPAEWDKDPSPIGDSVAEAITSPTRIRRPAIRRSFLQQAGGRPDLRGQEPFIEVSWE
VALDLVASELQRVRHEHGNQAIFGGSYGWGSAGRFHHAQSQLHRFLNCIGGYVFSTDSYSLGAGRVLMPHIVGNMDWLLA
AHTSWKNLAEHCELFVAFGGLPAKNAQTSPGGASDHLLSEALQRMSDAGVQFVNVSPLRDDLVGPTHNQWLAVRPGSDTA
LMMALSWVLISEGLHNEDFVQRYTVGYARFREYLLGHTDGQPKDPRWAEALTDIPAQQIVELARRMASKRTMINVAYSLQ
RSIHGEQPFWMTVTLAALLGQIGLPGAGFGLGYGCMNNTGSGRKAFSGPRFSQGSNPVRDFIPVARVTDMLLNPGTPFDY
NGQQRRYPDIRLVYWAGGNIFHHHQDLNRLLEAWQRPQTIIVHEQFWTAQARYADIVLPATTALERNDIGSSASDRFMIA
MQQAIEPVGESRDDYSILAALAERLGVAQAFTEGRDAREWLHFIYDESRQRAETFGITLPDFEQFWRDGVLEIDYPHTDN
VLLESFRHDPDAHPLPTPSGRIEIFSERIAGFGYADCPGHPVWLEKPAPTHALHLLSNQPKTRLHSQYDHGSYSRSSKIQ
AREPLTLNPLDARARGLVDGDVVKVFNERGAFLAGVIVSDGIRPGVVQIATGAWFDPLVHGERGSLEKHGNPNVITEDVG
ASSLSQGCSAQTASVDIVKWHQDLPPVTAFEPPSLL
>Mature_755_residues
SFTSLHWGAYRPQVEDGKLTGLLPAEWDKDPSPIGDSVAEAITSPTRIRRPAIRRSFLQQAGGRPDLRGQEPFIEVSWEV
ALDLVASELQRVRHEHGNQAIFGGSYGWGSAGRFHHAQSQLHRFLNCIGGYVFSTDSYSLGAGRVLMPHIVGNMDWLLAA
HTSWKNLAEHCELFVAFGGLPAKNAQTSPGGASDHLLSEALQRMSDAGVQFVNVSPLRDDLVGPTHNQWLAVRPGSDTAL
MMALSWVLISEGLHNEDFVQRYTVGYARFREYLLGHTDGQPKDPRWAEALTDIPAQQIVELARRMASKRTMINVAYSLQR
SIHGEQPFWMTVTLAALLGQIGLPGAGFGLGYGCMNNTGSGRKAFSGPRFSQGSNPVRDFIPVARVTDMLLNPGTPFDYN
GQQRRYPDIRLVYWAGGNIFHHHQDLNRLLEAWQRPQTIIVHEQFWTAQARYADIVLPATTALERNDIGSSASDRFMIAM
QQAIEPVGESRDDYSILAALAERLGVAQAFTEGRDAREWLHFIYDESRQRAETFGITLPDFEQFWRDGVLEIDYPHTDNV
LLESFRHDPDAHPLPTPSGRIEIFSERIAGFGYADCPGHPVWLEKPAPTHALHLLSNQPKTRLHSQYDHGSYSRSSKIQA
REPLTLNPLDARARGLVDGDVVKVFNERGAFLAGVIVSDGIRPGVVQIATGAWFDPLVHGERGSLEKHGNPNVITEDVGA
SSLSQGCSAQTASVDIVKWHQDLPPVTAFEPPSLL

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=777, Percent_Identity=38.7387387387387, Blast_Score=572, Evalue=1e-164,
Organism=Escherichia coli, GI145693196, Length=771, Percent_Identity=39.0402075226978, Blast_Score=551, Evalue=1e-158,
Organism=Escherichia coli, GI1787231, Length=781, Percent_Identity=40.3329065300896, Blast_Score=536, Evalue=1e-153,
Organism=Escherichia coli, GI87081797, Length=753, Percent_Identity=29.2164674634794, Blast_Score=299, Evalue=5e-82,
Organism=Escherichia coli, GI171474008, Length=746, Percent_Identity=29.7587131367292, Blast_Score=295, Evalue=8e-81,
Organism=Escherichia coli, GI1787870, Length=758, Percent_Identity=29.155672823219, Blast_Score=286, Evalue=5e-78,
Organism=Escherichia coli, GI3868721, Length=667, Percent_Identity=23.0884557721139, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.7.2.3 [H]

Molecular weight: Translated: 83766; Mature: 83635

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFTSLHWGAYRPQVEDGKLTGLLPAEWDKDPSPIGDSVAEAITSPTRIRRPAIRRSFLQ
CCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
QAGGRPDLRGQEPFIEVSWEVALDLVASELQRVRHEHGNQAIFGGSYGWGSAGRFHHAQS
HCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHH
QLHRFLNCIGGYVFSTDSYSLGAGRVLMPHIVGNMDWLLAAHTSWKNLAEHCELFVAFGG
HHHHHHHHHCCEEECCCCCCCCCCCEEHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCC
LPAKNAQTSPGGASDHLLSEALQRMSDAGVQFVNVSPLRDDLVGPTHNQWLAVRPGSDTA
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCHHHCCCCCCCCEEEEECCCCHH
LMMALSWVLISEGLHNEDFVQRYTVGYARFREYLLGHTDGQPKDPRWAEALTDIPAQQIV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHH
ELARRMASKRTMINVAYSLQRSIHGEQPFWMTVTLAALLGQIGLPGAGFGLGYGCMNNTG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SGRKAFSGPRFSQGSNPVRDFIPVARVTDMLLNPGTPFDYNGQQRRYPDIRLVYWAGGNI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCE
FHHHQDLNRLLEAWQRPQTIIVHEQFWTAQARYADIVLPATTALERNDIGSSASDRFMIA
EEHHHHHHHHHHHHCCCCEEEEECHHHCCCCCCEEEEECCHHHHHHCCCCCCCCCHHHHH
MQQAIEPVGESRDDYSILAALAERLGVAQAFTEGRDAREWLHFIYDESRQRAETFGITLP
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
DFEQFWRDGVLEIDYPHTDNVLLESFRHDPDAHPLPTPSGRIEIFSERIAGFGYADCPGH
CHHHHHHCCCEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
PVWLEKPAPTHALHLLSNQPKTRLHSQYDHGSYSRSSKIQAREPLTLNPLDARARGLVDG
CEEECCCCCHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCH
DVVKVFNERGAFLAGVIVSDGIRPGVVQIATGAWFDPLVHGERGSLEKHGNPNVITEDVG
HHHHHHHHCCCEEEEHHHHCCCCCCEEEEECCCCCCHHHCCCCCCCCCCCCCCEEECCCC
ASSLSQGCSAQTASVDIVKWHQDLPPVTAFEPPSLL
HHHHHCCCCCCCCEEEEEEHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SFTSLHWGAYRPQVEDGKLTGLLPAEWDKDPSPIGDSVAEAITSPTRIRRPAIRRSFLQ
CCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHH
QAGGRPDLRGQEPFIEVSWEVALDLVASELQRVRHEHGNQAIFGGSYGWGSAGRFHHAQS
HCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCHHHHHH
QLHRFLNCIGGYVFSTDSYSLGAGRVLMPHIVGNMDWLLAAHTSWKNLAEHCELFVAFGG
HHHHHHHHHCCEEECCCCCCCCCCCEEHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCC
LPAKNAQTSPGGASDHLLSEALQRMSDAGVQFVNVSPLRDDLVGPTHNQWLAVRPGSDTA
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCHHHCCCCCCCCEEEEECCCCHH
LMMALSWVLISEGLHNEDFVQRYTVGYARFREYLLGHTDGQPKDPRWAEALTDIPAQQIV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCHHHHH
ELARRMASKRTMINVAYSLQRSIHGEQPFWMTVTLAALLGQIGLPGAGFGLGYGCMNNTG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
SGRKAFSGPRFSQGSNPVRDFIPVARVTDMLLNPGTPFDYNGQQRRYPDIRLVYWAGGNI
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCE
FHHHQDLNRLLEAWQRPQTIIVHEQFWTAQARYADIVLPATTALERNDIGSSASDRFMIA
EEHHHHHHHHHHHHCCCCEEEEECHHHCCCCCCEEEEECCHHHHHHCCCCCCCCCHHHHH
MQQAIEPVGESRDDYSILAALAERLGVAQAFTEGRDAREWLHFIYDESRQRAETFGITLP
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCC
DFEQFWRDGVLEIDYPHTDNVLLESFRHDPDAHPLPTPSGRIEIFSERIAGFGYADCPGH
CHHHHHHCCCEEECCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCC
PVWLEKPAPTHALHLLSNQPKTRLHSQYDHGSYSRSSKIQAREPLTLNPLDARARGLVDG
CEEECCCCCHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCH
DVVKVFNERGAFLAGVIVSDGIRPGVVQIATGAWFDPLVHGERGSLEKHGNPNVITEDVG
HHHHHHHHCCCEEEEHHHHCCCCCCEEEEECCCCCCHHHCCCCCCCCCCCCCCEEECCCC
ASSLSQGCSAQTASVDIVKWHQDLPPVTAFEPPSLL
HHHHHCCCCCCCCEEEEEEHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8856102; 8890911; 8890912; 10835270; 10985771 [H]