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The map label for this gene is sdaA [H]

Identifier: 66046751

GI number: 66046751

Start: 4197604

End: 4198980

Strand: Direct

Name: sdaA [H]

Synonym: Psyr_3522

Alternate gene names: 66046751

Gene position: 4197604-4198980 (Clockwise)

Preceding gene: 66046749

Following gene: 66046755

Centisome position: 68.88

GC content: 62.02

Gene sequence:

>1377_bases
ATGGCTATCAGCGTCTTCGACATGTTCAAAATCGGCATCGGGCCGTCCAGTTCCCACACCGTCGGGCCAATGCGCGCCGG
TGCGCTGTTCGTGACCGAGCTGCGCGACCACAACCGGTTGCACAGCGTAGAACGGATCGAGGTGCGATTGTACGGTTCTC
TGTCGGCCACGGGCATCGGTCACGGCAGTGATCGCGCGACAGTCATGGGCCTGATGGGCGAATGGCCGGACCAGATCGAC
CCCAGCCAGGTCAACCAGCGTATCGACGCGCTGCGTGCCGATAACCAGCTGATGCTGGCGGGCGAACAGGCCATCACCTT
CGTCTGGGAGCGAGACATGTGCCTGCTCGATGAAAGCCTCCCCTACCATCCCAACGGCATGACCCTGTGTGCCTACGGCA
AGAACGGCGAACTCCACGAGCAGACTTATTATTCGGTGGGCGGCGGTTTCGTAATCGATGCCGAACAGGCCGCCAGCGGC
GTGCTGGACAACGACACAACCGTCCTGCCCTATGATTTTTTCAGTGGCGCGCAGTTGCTCAAGCTGTGCAAGACCCACGG
CATGAGCATTTCCGAACTGATGATGGCCAATGAAAAGGTCTGGCGCAGCGAGGAGGAAATCCGCGAGAAAATCATGGTGA
TCTGGGCCGCAATGCGCGCCTGCGTCGACAAGGGCCTGTTGGAAACCGGCATCCTGCCCGGTGGCCTGAACGTGCGGCGG
CGTGCCTACCGCCTGCATCAGAACCTGCAGAACCTGGATAACCCCAACGTAATCGGCTCGACCCTGAGCGCCATGGAATG
GGTCAACCTGTTCGCCCTCGCAGTCAACGAAGAAAACGCCGCAGGCGGGCGCATGGTGACCGCGCCCACCAACGGCGCAG
CTGGCATCGTGCCCGCCGTGCTGCATTACTTCATGAAATTCAAGCCCACGGCCAATGACGATGACGTGGTGCGCTTTTTC
CTGAGCGCCGCTGCGGTCGGCATTCTGTGCAAGAAAAACGCTTCGATTTCCGGTGCCGAGGTCGGTTGTCAGGGTGAGGT
AGGATCGGCCTGCGCAATGGCCGCCGCCGGTCTGGCGGAGATCCTCGGCGCGACGCCCGAGCAGGTAGAGAACGCTGCCG
AGATTGGCCTGGAGCATAATCTGGGGCTGACCTGCGACCCGGTCGGCGGGCTGGTGCAGATCCCCTGCATCGAGCGCAAT
GCGATTGCTGCCGTAAAGGCCATCAATGCCGCCCAGATGGCCCTGCGCGGCGACGGCGAGCACCACATCTCGCTGGACCA
TGCCATCCGCACCATGCGTGACACCGGCGCCGACATGCACGACAAATACAAGGAAACCTCACGCGGCGGGCTGGCGGTCA
ACCTGATCGAGTGCTGA

Upstream 100 bases:

>100_bases
AACAATCGTTTGTCGTTTCGACAGCCGAAGCCAAAGATGAGTAACAGAAAAAGGGGAATACCAAATTCCCGTGCATCATC
TCACCTGAAGGACCTTCGTG

Downstream 100 bases:

>100_bases
CAGACATCCACCGGCGTCGCGACGTATTCGAGAGTGTCCGGGACGGTACATCCCCTGCGGAGGTACCGTCCTTTTCGCGA
ACCGCTTCGCTCCTATGACC

Product: Iron-sulfur-dependent L-serine dehydratase single chain form

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MAISVFDMFKIGIGPSSSHTVGPMRAGALFVTELRDHNRLHSVERIEVRLYGSLSATGIGHGSDRATVMGLMGEWPDQID
PSQVNQRIDALRADNQLMLAGEQAITFVWERDMCLLDESLPYHPNGMTLCAYGKNGELHEQTYYSVGGGFVIDAEQAASG
VLDNDTTVLPYDFFSGAQLLKLCKTHGMSISELMMANEKVWRSEEEIREKIMVIWAAMRACVDKGLLETGILPGGLNVRR
RAYRLHQNLQNLDNPNVIGSTLSAMEWVNLFALAVNEENAAGGRMVTAPTNGAAGIVPAVLHYFMKFKPTANDDDVVRFF
LSAAAVGILCKKNASISGAEVGCQGEVGSACAMAAAGLAEILGATPEQVENAAEIGLEHNLGLTCDPVGGLVQIPCIERN
AIAAVKAINAAQMALRGDGEHHISLDHAIRTMRDTGADMHDKYKETSRGGLAVNLIEC

Sequences:

>Translated_458_residues
MAISVFDMFKIGIGPSSSHTVGPMRAGALFVTELRDHNRLHSVERIEVRLYGSLSATGIGHGSDRATVMGLMGEWPDQID
PSQVNQRIDALRADNQLMLAGEQAITFVWERDMCLLDESLPYHPNGMTLCAYGKNGELHEQTYYSVGGGFVIDAEQAASG
VLDNDTTVLPYDFFSGAQLLKLCKTHGMSISELMMANEKVWRSEEEIREKIMVIWAAMRACVDKGLLETGILPGGLNVRR
RAYRLHQNLQNLDNPNVIGSTLSAMEWVNLFALAVNEENAAGGRMVTAPTNGAAGIVPAVLHYFMKFKPTANDDDVVRFF
LSAAAVGILCKKNASISGAEVGCQGEVGSACAMAAAGLAEILGATPEQVENAAEIGLEHNLGLTCDPVGGLVQIPCIERN
AIAAVKAINAAQMALRGDGEHHISLDHAIRTMRDTGADMHDKYKETSRGGLAVNLIEC
>Mature_457_residues
AISVFDMFKIGIGPSSSHTVGPMRAGALFVTELRDHNRLHSVERIEVRLYGSLSATGIGHGSDRATVMGLMGEWPDQIDP
SQVNQRIDALRADNQLMLAGEQAITFVWERDMCLLDESLPYHPNGMTLCAYGKNGELHEQTYYSVGGGFVIDAEQAASGV
LDNDTTVLPYDFFSGAQLLKLCKTHGMSISELMMANEKVWRSEEEIREKIMVIWAAMRACVDKGLLETGILPGGLNVRRR
AYRLHQNLQNLDNPNVIGSTLSAMEWVNLFALAVNEENAAGGRMVTAPTNGAAGIVPAVLHYFMKFKPTANDDDVVRFFL
SAAAVGILCKKNASISGAEVGCQGEVGSACAMAAAGLAEILGATPEQVENAAEIGLEHNLGLTCDPVGGLVQIPCIERNA
IAAVKAINAAQMALRGDGEHHISLDHAIRTMRDTGADMHDKYKETSRGGLAVNLIEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1789161, Length=457, Percent_Identity=52.7352297592998, Blast_Score=468, Evalue=1e-133,
Organism=Escherichia coli, GI48994925, Length=455, Percent_Identity=52.5274725274725, Blast_Score=465, Evalue=1e-132,
Organism=Escherichia coli, GI1788116, Length=457, Percent_Identity=53.3916849015317, Blast_Score=464, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 49326; Mature: 49195

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAISVFDMFKIGIGPSSSHTVGPMRAGALFVTELRDHNRLHSVERIEVRLYGSLSATGIG
CEEEEEEHHEECCCCCCCCCCCCCCCCEEEEEEHHCCHHHCCCEEEEEEEEECEEECCCC
HGSDRATVMGLMGEWPDQIDPSQVNQRIDALRADNQLMLAGEQAITFVWERDMCLLDESL
CCCCCCEEEEHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCEEEEEEECCEEEECCCC
PYHPNGMTLCAYGKNGELHEQTYYSVGGGFVIDAEQAASGVLDNDTTVLPYDFFSGAQLL
CCCCCCEEEEEECCCCCCCHHHEEECCCCEEEEHHHHHCCCCCCCCEEEEEHHCCHHHHH
KLCKTHGMSISELMMANEKVWRSEEEIREKIMVIWAAMRACVDKGLLETGILPGGLNVRR
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHH
RAYRLHQNLQNLDNPNVIGSTLSAMEWVNLFALAVNEENAAGGRMVTAPTNGAAGIVPAV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEECCCCCCCCEEEECCCCCCCHHHHHH
LHYFMKFKPTANDDDVVRFFLSAAAVGILCKKNASISGAEVGCQGEVGSACAMAAAGLAE
HHHHHHCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ILGATPEQVENAAEIGLEHNLGLTCDPVGGLVQIPCIERNAIAAVKAINAAQMALRGDGE
HHCCCHHHHHHHHHCCCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCC
HHISLDHAIRTMRDTGADMHDKYKETSRGGLAVNLIEC
CEEEHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECC
>Mature Secondary Structure 
AISVFDMFKIGIGPSSSHTVGPMRAGALFVTELRDHNRLHSVERIEVRLYGSLSATGIG
EEEEEEHHEECCCCCCCCCCCCCCCCEEEEEEHHCCHHHCCCEEEEEEEEECEEECCCC
HGSDRATVMGLMGEWPDQIDPSQVNQRIDALRADNQLMLAGEQAITFVWERDMCLLDESL
CCCCCCEEEEHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCEEEEEEECCEEEECCCC
PYHPNGMTLCAYGKNGELHEQTYYSVGGGFVIDAEQAASGVLDNDTTVLPYDFFSGAQLL
CCCCCCEEEEEECCCCCCCHHHEEECCCCEEEEHHHHHCCCCCCCCEEEEEHHCCHHHHH
KLCKTHGMSISELMMANEKVWRSEEEIREKIMVIWAAMRACVDKGLLETGILPGGLNVRR
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCHHHH
RAYRLHQNLQNLDNPNVIGSTLSAMEWVNLFALAVNEENAAGGRMVTAPTNGAAGIVPAV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHEEEEEECCCCCCCCEEEECCCCCCCHHHHHH
LHYFMKFKPTANDDDVVRFFLSAAAVGILCKKNASISGAEVGCQGEVGSACAMAAAGLAE
HHHHHHCCCCCCCHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ILGATPEQVENAAEIGLEHNLGLTCDPVGGLVQIPCIERNAIAAVKAINAAQMALRGDGE
HHCCCHHHHHHHHHCCCCCCCCEEECCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCC
HHISLDHAIRTMRDTGADMHDKYKETSRGGLAVNLIEC
CEEEHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]