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The map label for this gene is flhF [H]

Identifier: 66046668

GI number: 66046668

Start: 4102262

End: 4103590

Strand: Reverse

Name: flhF [H]

Synonym: Psyr_3439

Alternate gene names: 66046668

Gene position: 4103590-4102262 (Counterclockwise)

Preceding gene: 66046669

Following gene: 66046667

Centisome position: 67.34

GC content: 61.7

Gene sequence:

>1329_bases
ATGCAAGTTAAGCGATTTTTCGCCGCCGATATGCGTCAAGCCATGAAGCTGGTTCGCGATGAGCTGGGCGCTGAAGCGGC
CATCATCGGTAACCGGCGCATTGCCGGTGGCGTAGAGCTGACTGCCGCTCTGGATTACAAGCTGTCCGCCCTGGCACCGC
GTGTGCCGAACATGGAGCTGGAAGACGAGTTGCGCAAGACTCAGTCGCGCATCGTCTCCGCCCAGGCCGAATTGAACAAC
CGCAGCGACAGCGACGCATCGGTCAACCTGCAGCTGTTTTCCGGCAAGCCGGGCAACCCTGCCGATACGCACATCGAGCC
GACACTCGAAGAGCCGCCGCGTCCATTCGCGTACGCACCGCCACAGGCCGCCGAGCCTGCCATTGGCCAGCGCGCCTATG
ACTCGATGCGCTCCGAATTGAACGGCCTGCGTGAGCTGCTGGAAGTCCAGCTCGGCTCGCTGGCCTGGAACCAGCTGCAG
GGCACTCGTCCGCAGCAGGCCAACCTGTGGCGCCGCCTGCAACGTGTCGGCCTGTCCGGCCCGCTGTCACGCGACCTGCT
GTCGATGATTCCGGAGATCGACGAGCCTCGTCAGGCCTGGCGCATGCTGCTGGCGCACCTGGCCCGCATGATCGCCGTCC
CTGAAGTCGAGCCACTCGAAGAGGGCGGCGTGATTGCAATGGTCGGTCCTGCCGGCATGGGCAAGACCACCACGCTGGCC
AAACTGGCAGCACGTTACGTGTTGAAGTACGGCCCGCAGAATATCGCACTGGTCAGCATGGACAGTTTCCGCATCGGCGC
GCAGGAGCAGCTCAAGACCCTTGGGCGCATCCTCAACGTACCGGTCACCCATATCGATCCTGGCCAGTCTCTGGTTCAGG
CGCTGGAACCGCTGCTGCGCAAGCGGGTGGTGCTGATTGACACCGCCGGCCTGCAGGCCAGTGATCCTGCGCTGCGCATG
CAGCTGGAAAGCCTCGCGGGTCGTGGCATCAAGTCGCGCAACTATCTGGTACTGGCAACCACCAGCCAGAAGCAGGTGCT
GACAGCCGCGTATCACAGTTACAAACGTTGTGGCCTGGCCGGATGCATTCTGACCAAGCTTGATGAAACAGCCAGCCTCG
GTGAAGTCCTGAGCCTGGCGATCAGTCACGAATTACCTGTGGCCTACCTCACGGACGGACCACGCATTCCTGATGACCTG
CATACCCCGCGTCGTCATCAACTGGTAAGCCGCGCGGTGAGTGTGCAAATGCAGGATGAGCCTAGTGAAGAAGCAATGGC
TGATATGTTTGCTGACCTCTATCACACCCCTGGCAAGAGAGTGGGTTAA

Upstream 100 bases:

>100_bases
CTGTACCGAACATGCATGTTCTGGCGTATCAGGAAATTCCGGACAACAAGCAAGTAACCATCGTAGCGACTGTCGGGCCA
AACGGCTGAGGTAGTGAGTC

Downstream 100 bases:

>100_bases
GTGATGGATATTATTGGAATGTCCCTGCGTCAACGGTCTGCCATGCGGTGTTCATTTGCGCACGTGCAGCCCTCGATGTG
GTTTCGGTCTACGCAAGACA

Product: flagellar biosynthesis regulator FlhF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MQVKRFFAADMRQAMKLVRDELGAEAAIIGNRRIAGGVELTAALDYKLSALAPRVPNMELEDELRKTQSRIVSAQAELNN
RSDSDASVNLQLFSGKPGNPADTHIEPTLEEPPRPFAYAPPQAAEPAIGQRAYDSMRSELNGLRELLEVQLGSLAWNQLQ
GTRPQQANLWRRLQRVGLSGPLSRDLLSMIPEIDEPRQAWRMLLAHLARMIAVPEVEPLEEGGVIAMVGPAGMGKTTTLA
KLAARYVLKYGPQNIALVSMDSFRIGAQEQLKTLGRILNVPVTHIDPGQSLVQALEPLLRKRVVLIDTAGLQASDPALRM
QLESLAGRGIKSRNYLVLATTSQKQVLTAAYHSYKRCGLAGCILTKLDETASLGEVLSLAISHELPVAYLTDGPRIPDDL
HTPRRHQLVSRAVSVQMQDEPSEEAMADMFADLYHTPGKRVG

Sequences:

>Translated_442_residues
MQVKRFFAADMRQAMKLVRDELGAEAAIIGNRRIAGGVELTAALDYKLSALAPRVPNMELEDELRKTQSRIVSAQAELNN
RSDSDASVNLQLFSGKPGNPADTHIEPTLEEPPRPFAYAPPQAAEPAIGQRAYDSMRSELNGLRELLEVQLGSLAWNQLQ
GTRPQQANLWRRLQRVGLSGPLSRDLLSMIPEIDEPRQAWRMLLAHLARMIAVPEVEPLEEGGVIAMVGPAGMGKTTTLA
KLAARYVLKYGPQNIALVSMDSFRIGAQEQLKTLGRILNVPVTHIDPGQSLVQALEPLLRKRVVLIDTAGLQASDPALRM
QLESLAGRGIKSRNYLVLATTSQKQVLTAAYHSYKRCGLAGCILTKLDETASLGEVLSLAISHELPVAYLTDGPRIPDDL
HTPRRHQLVSRAVSVQMQDEPSEEAMADMFADLYHTPGKRVG
>Mature_442_residues
MQVKRFFAADMRQAMKLVRDELGAEAAIIGNRRIAGGVELTAALDYKLSALAPRVPNMELEDELRKTQSRIVSAQAELNN
RSDSDASVNLQLFSGKPGNPADTHIEPTLEEPPRPFAYAPPQAAEPAIGQRAYDSMRSELNGLRELLEVQLGSLAWNQLQ
GTRPQQANLWRRLQRVGLSGPLSRDLLSMIPEIDEPRQAWRMLLAHLARMIAVPEVEPLEEGGVIAMVGPAGMGKTTTLA
KLAARYVLKYGPQNIALVSMDSFRIGAQEQLKTLGRILNVPVTHIDPGQSLVQALEPLLRKRVVLIDTAGLQASDPALRM
QLESLAGRGIKSRNYLVLATTSQKQVLTAAYHSYKRCGLAGCILTKLDETASLGEVLSLAISHELPVAYLTDGPRIPDDL
HTPRRHQLVSRAVSVQMQDEPSEEAMADMFADLYHTPGKRVG

Specific function: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum [H]

COG id: COG1419

COG function: function code N; Flagellar GTP-binding protein

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI226371618, Length=195, Percent_Identity=28.7179487179487, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI4507215, Length=195, Percent_Identity=28.7179487179487, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789874, Length=199, Percent_Identity=31.6582914572864, Blast_Score=78, Evalue=9e-16,
Organism=Drosophila melanogaster, GI17647949, Length=238, Percent_Identity=25.2100840336134, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR020006 [H]

Pfam domain/function: PF00448 SRP54 [H]

EC number: NA

Molecular weight: Translated: 48472; Mature: 48472

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKRFFAADMRQAMKLVRDELGAEAAIIGNRRIAGGVELTAALDYKLSALAPRVPNMEL
CCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCEECCCEEEEEECCHHHHHHCCCCCCCCH
EDELRKTQSRIVSAQAELNNRSDSDASVNLQLFSGKPGNPADTHIEPTLEEPPRPFAYAP
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
PQAAEPAIGQRAYDSMRSELNGLRELLEVQLGSLAWNQLQGTRPQQANLWRRLQRVGLSG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
PLSRDLLSMIPEIDEPRQAWRMLLAHLARMIAVPEVEPLEEGGVIAMVGPAGMGKTTTLA
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHH
KLAARYVLKYGPQNIALVSMDSFRIGAQEQLKTLGRILNVPVTHIDPGQSLVQALEPLLR
HHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
KRVVLIDTAGLQASDPALRMQLESLAGRGIKSRNYLVLATTSQKQVLTAAYHSYKRCGLA
CCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCHH
GCILTKLDETASLGEVLSLAISHELPVAYLTDGPRIPDDLHTPRRHQLVSRAVSVQMQDE
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHEEECCC
PSEEAMADMFADLYHTPGKRVG
CHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQVKRFFAADMRQAMKLVRDELGAEAAIIGNRRIAGGVELTAALDYKLSALAPRVPNMEL
CCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCEECCCEEEEEECCHHHHHHCCCCCCCCH
EDELRKTQSRIVSAQAELNNRSDSDASVNLQLFSGKPGNPADTHIEPTLEEPPRPFAYAP
HHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
PQAAEPAIGQRAYDSMRSELNGLRELLEVQLGSLAWNQLQGTRPQQANLWRRLQRVGLSG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
PLSRDLLSMIPEIDEPRQAWRMLLAHLARMIAVPEVEPLEEGGVIAMVGPAGMGKTTTLA
CHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCHHHHH
KLAARYVLKYGPQNIALVSMDSFRIGAQEQLKTLGRILNVPVTHIDPGQSLVQALEPLLR
HHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
KRVVLIDTAGLQASDPALRMQLESLAGRGIKSRNYLVLATTSQKQVLTAAYHSYKRCGLA
CCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCHH
GCILTKLDETASLGEVLSLAISHELPVAYLTDGPRIPDDLHTPRRHQLVSRAVSVQMQDE
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHEEECCC
PSEEAMADMFADLYHTPGKRVG
CHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9503621 [H]