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The map label for this gene is flhA [H]

Identifier: 66046669

GI number: 66046669

Start: 4103602

End: 4105731

Strand: Reverse

Name: flhA [H]

Synonym: Psyr_3440

Alternate gene names: 66046669

Gene position: 4105731-4103602 (Counterclockwise)

Preceding gene: 66046670

Following gene: 66046668

Centisome position: 67.38

GC content: 58.69

Gene sequence:

>2130_bases
GTGGATCGCTCTCAATTACTCAGTAGCGCACGCAGCAATATCACAGGCCTTGGCCGTGGTCAGTTGGGCGTTCCGTTGTT
GTTGCTGGTCATGATGGCAATGATGATGTTGCCGATGCCGCCGTTCCTGCTGGACGTGTTCTTCACGTTCAACATTGCAC
TGTCCATCGTCGTGCTGCTGGTGTGCGTGTACGCACTGCGGCCGCTGGACTTCTCGGTATTTCCGACCATTCTGCTGGTC
GCCACGTTGCTGCGTCTGGCGCTGAACGTCGCTTCCACGCGGGTGGTCATGCTTCATGGTCAGGACGGCCACGCCGCTGC
GGGCAAGGTGATTCAGGCCTTCGGTGAAGTGGTGATCGGTGGCAACTACGTCGTCGGTATCGTGGTGTTCGCGATTCTGA
TGATCATCAACTTCGTGGTCATCACCAAGGGTGCCGGCCGTATTTCCGAGGTGAGCGCGCGCTTCACCCTCGACGCGATG
CCCGGCAAACAGATGGCGATCGACGCCGACCTCAACGCCGGCCTCATCGATCAGCCTGAAGCCAAGCGCCGCCGTGCCGA
AGTCGCCCAGGAAGCCGAGTTCTACGGTTCCATGGACGGTGCCAGTAAATTCGTGCGCGGCGATGCGATTGCCGGTCTGC
TGATTCTGTTCATCAATCTGATCGGCGGCATGCTGGTCGGCATCCTGCAACACAACATGACCTTCGCCGACGCCGGCCGC
GTTTACACCCTGCTGACCATCGGTGACGGTTTGGTGGCGCAATTGCCATCACTGCTGCTGTCCACCGCCGCAGCGATCAT
GGTGACCCGTGCTTCCGGTTCGGAAGAGATGGGCAAGCTGATCAATCGTCAGATGTTCGCCTCGCCCAAGGCGCTGGGGG
TTTCCGCTGCAATCATGATCGTCATGGGCCTTGTCCCGGGCATGCCGCACTTTTCCTTTATCAGTCTCGGGCTGGTTGCC
GCAGGCGGCGCCTACCTGCTCTGGAAAAAAGAAAATCAGGTGAAGGTCGAGGCCATCGCCGAAGTGCAGCGCCAGCAAGA
CCTGCTGCCTTCGCCGACCCGTGTTCAGGATGCCAAAGAACTGGGTTGGGATGACGTGACGCCCATCGATATCATTGGCC
TGGAAGTGGGTTATCGCCTGATTCCGCTGGTGGATCGCAATCAAGGTGGCCAGTTGCTGGCGCGTATCAAGGGTGTGCGC
AAGAAGCTCTCGCAAGAGCTCGGTTTCCTGATGCCTACCGTGCACATTCGCGACAACCTCGATCTGGCGCCCAGCGCCTA
TCGTCTGACGCTGATGGGTGTGATTCTGGCCGAGGCCGAGATCTACCCGGATCGCGAACTGGCGATCAACCCCGGTCAAG
TGTTCGGCACCCTGAACGGCATTACCGCCAGAGACCCGGCGTTTGGTCTGGAAGCCGTGTGGATCGAAATCAGCCAGCGC
AGTCAGGCGCAGTCACTGGGTTACACCGTGGTCGATGCCAGTACGGTAGTGGCAACCCACCTGAACCAGATTCTCTACAA
ACATTCGCATGAGCTGATCGGCCACGAAGAAGTCCAGCAATTGATGCAATTGCTGGCCAAAAGCTCGCCCAAGCTGGCTG
AAGAGCTGGTACCGGGCGTGCTGTCGCTGTCCTCGCTGCTCAACGTGCTGCAGGCGCTGCTGGCTGAACACGTACCTGTG
CGGGATATTCGCAGCATTGCAGAGGCTATCGCCAACAACGCCGGGAAGAGTCAAGATACCGCCGCTTTGGTGGCCGCAGT
GCGCGTGGGTCTGAGCCGCGCAATCGTCCAAAGCATTGTAGGCGTTGAGCCGGAGCTGCCTGTTATCACTCTGGAGCCAA
GGTTGGAACAGATATTGCTCAATAGTTTGCAGAAGGCTGGTCAGGGTCAGGAAGAAGGCGTTCTTCTTGAGCCAAGCATG
GCTGAGAAGCTCCAGCGTTCGTTGATCGAGGCCGCCCAGCGTCAGGAGATGCAGGGGTTGCCGGTAATTCTTCTGGTAGC
AGGGCCTGTCCGGGCGATGCTGTCACGATTTGGACGATTGGCTGTACCGAACATGCATGTTCTGGCGTATCAGGAAATTC
CGGACAACAAGCAAGTAACCATCGTAGCGACTGTCGGGCCAAACGGCTGA

Upstream 100 bases:

>100_bases
CGCCACTGGCTTTGTAAAAGTTGGACAGATTTTTGCAACAGGGTCGATACAGGTCGCCATCGGCGTCAATGTTTTGATCT
AGTGCGCAGGTAACGAATCA

Downstream 100 bases:

>100_bases
GGTAGTGAGTCATGCAAGTTAAGCGATTTTTCGCCGCCGATATGCGTCAAGCCATGAAGCTGGTTCGCGATGAGCTGGGC
GCTGAAGCGGCCATCATCGG

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 709; Mature: 709

Protein sequence:

>709_residues
MDRSQLLSSARSNITGLGRGQLGVPLLLLVMMAMMMLPMPPFLLDVFFTFNIALSIVVLLVCVYALRPLDFSVFPTILLV
ATLLRLALNVASTRVVMLHGQDGHAAAGKVIQAFGEVVIGGNYVVGIVVFAILMIINFVVITKGAGRISEVSARFTLDAM
PGKQMAIDADLNAGLIDQPEAKRRRAEVAQEAEFYGSMDGASKFVRGDAIAGLLILFINLIGGMLVGILQHNMTFADAGR
VYTLLTIGDGLVAQLPSLLLSTAAAIMVTRASGSEEMGKLINRQMFASPKALGVSAAIMIVMGLVPGMPHFSFISLGLVA
AGGAYLLWKKENQVKVEAIAEVQRQQDLLPSPTRVQDAKELGWDDVTPIDIIGLEVGYRLIPLVDRNQGGQLLARIKGVR
KKLSQELGFLMPTVHIRDNLDLAPSAYRLTLMGVILAEAEIYPDRELAINPGQVFGTLNGITARDPAFGLEAVWIEISQR
SQAQSLGYTVVDASTVVATHLNQILYKHSHELIGHEEVQQLMQLLAKSSPKLAEELVPGVLSLSSLLNVLQALLAEHVPV
RDIRSIAEAIANNAGKSQDTAALVAAVRVGLSRAIVQSIVGVEPELPVITLEPRLEQILLNSLQKAGQGQEEGVLLEPSM
AEKLQRSLIEAAQRQEMQGLPVILLVAGPVRAMLSRFGRLAVPNMHVLAYQEIPDNKQVTIVATVGPNG

Sequences:

>Translated_709_residues
MDRSQLLSSARSNITGLGRGQLGVPLLLLVMMAMMMLPMPPFLLDVFFTFNIALSIVVLLVCVYALRPLDFSVFPTILLV
ATLLRLALNVASTRVVMLHGQDGHAAAGKVIQAFGEVVIGGNYVVGIVVFAILMIINFVVITKGAGRISEVSARFTLDAM
PGKQMAIDADLNAGLIDQPEAKRRRAEVAQEAEFYGSMDGASKFVRGDAIAGLLILFINLIGGMLVGILQHNMTFADAGR
VYTLLTIGDGLVAQLPSLLLSTAAAIMVTRASGSEEMGKLINRQMFASPKALGVSAAIMIVMGLVPGMPHFSFISLGLVA
AGGAYLLWKKENQVKVEAIAEVQRQQDLLPSPTRVQDAKELGWDDVTPIDIIGLEVGYRLIPLVDRNQGGQLLARIKGVR
KKLSQELGFLMPTVHIRDNLDLAPSAYRLTLMGVILAEAEIYPDRELAINPGQVFGTLNGITARDPAFGLEAVWIEISQR
SQAQSLGYTVVDASTVVATHLNQILYKHSHELIGHEEVQQLMQLLAKSSPKLAEELVPGVLSLSSLLNVLQALLAEHVPV
RDIRSIAEAIANNAGKSQDTAALVAAVRVGLSRAIVQSIVGVEPELPVITLEPRLEQILLNSLQKAGQGQEEGVLLEPSM
AEKLQRSLIEAAQRQEMQGLPVILLVAGPVRAMLSRFGRLAVPNMHVLAYQEIPDNKQVTIVATVGPNG
>Mature_709_residues
MDRSQLLSSARSNITGLGRGQLGVPLLLLVMMAMMMLPMPPFLLDVFFTFNIALSIVVLLVCVYALRPLDFSVFPTILLV
ATLLRLALNVASTRVVMLHGQDGHAAAGKVIQAFGEVVIGGNYVVGIVVFAILMIINFVVITKGAGRISEVSARFTLDAM
PGKQMAIDADLNAGLIDQPEAKRRRAEVAQEAEFYGSMDGASKFVRGDAIAGLLILFINLIGGMLVGILQHNMTFADAGR
VYTLLTIGDGLVAQLPSLLLSTAAAIMVTRASGSEEMGKLINRQMFASPKALGVSAAIMIVMGLVPGMPHFSFISLGLVA
AGGAYLLWKKENQVKVEAIAEVQRQQDLLPSPTRVQDAKELGWDDVTPIDIIGLEVGYRLIPLVDRNQGGQLLARIKGVR
KKLSQELGFLMPTVHIRDNLDLAPSAYRLTLMGVILAEAEIYPDRELAINPGQVFGTLNGITARDPAFGLEAVWIEISQR
SQAQSLGYTVVDASTVVATHLNQILYKHSHELIGHEEVQQLMQLLAKSSPKLAEELVPGVLSLSSLLNVLQALLAEHVPV
RDIRSIAEAIANNAGKSQDTAALVAAVRVGLSRAIVQSIVGVEPELPVITLEPRLEQILLNSLQKAGQGQEEGVLLEPSM
AEKLQRSLIEAAQRQEMQGLPVILLVAGPVRAMLSRFGRLAVPNMHVLAYQEIPDNKQVTIVATVGPNG

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=685, Percent_Identity=53.1386861313869, Blast_Score=691, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 76219; Mature: 76219

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRSQLLSSARSNITGLGRGQLGVPLLLLVMMAMMMLPMPPFLLDVFFTFNIALSIVVLL
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VCVYALRPLDFSVFPTILLVATLLRLALNVASTRVVMLHGQDGHAAAGKVIQAFGEVVIG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCEEEC
GNYVVGIVVFAILMIINFVVITKGAGRISEVSARFTLDAMPGKQMAIDADLNAGLIDQPE
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCCCH
AKRRRAEVAQEAEFYGSMDGASKFVRGDAIAGLLILFINLIGGMLVGILQHNMTFADAGR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCC
VYTLLTIGDGLVAQLPSLLLSTAAAIMVTRASGSEEMGKLINRQMFASPKALGVSAAIMI
EEEEEEECCCHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
VMGLVPGMPHFSFISLGLVAAGGAYLLWKKENQVKVEAIAEVQRQQDLLPSPTRVQDAKE
HHHHCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHH
LGWDDVTPIDIIGLEVGYRLIPLVDRNQGGQLLARIKGVRKKLSQELGFLMPTVHIRDNL
CCCCCCCCCEEEEHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCC
DLAPSAYRLTLMGVILAEAEIYPDRELAINPGQVFGTLNGITARDPAFGLEAVWIEISQR
CCCCCHHHHHHHHHHHHHHHCCCCCCEEECCHHHHEECCCCCCCCCCCCCEEEEEEEHHH
SQAQSLGYTVVDASTVVATHLNQILYKHSHELIGHEEVQQLMQLLAKSSPKLAEELVPGV
HHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHH
LSLSSLLNVLQALLAEHVPVRDIRSIAEAIANNAGKSQDTAALVAAVRVGLSRAIVQSIV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GVEPELPVITLEPRLEQILLNSLQKAGQGQEEGVLLEPSMAEKLQRSLIEAAQRQEMQGL
CCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCC
PVILLVAGPVRAMLSRFGRLAVPNMHVLAYQEIPDNKQVTIVATVGPNG
CEEEEECCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MDRSQLLSSARSNITGLGRGQLGVPLLLLVMMAMMMLPMPPFLLDVFFTFNIALSIVVLL
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VCVYALRPLDFSVFPTILLVATLLRLALNVASTRVVMLHGQDGHAAAGKVIQAFGEVVIG
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHHCCEEEC
GNYVVGIVVFAILMIINFVVITKGAGRISEVSARFTLDAMPGKQMAIDADLNAGLIDQPE
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCCCH
AKRRRAEVAQEAEFYGSMDGASKFVRGDAIAGLLILFINLIGGMLVGILQHNMTFADAGR
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCC
VYTLLTIGDGLVAQLPSLLLSTAAAIMVTRASGSEEMGKLINRQMFASPKALGVSAAIMI
EEEEEEECCCHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
VMGLVPGMPHFSFISLGLVAAGGAYLLWKKENQVKVEAIAEVQRQQDLLPSPTRVQDAKE
HHHHCCCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCCHHHHHH
LGWDDVTPIDIIGLEVGYRLIPLVDRNQGGQLLARIKGVRKKLSQELGFLMPTVHIRDNL
CCCCCCCCCEEEEHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCC
DLAPSAYRLTLMGVILAEAEIYPDRELAINPGQVFGTLNGITARDPAFGLEAVWIEISQR
CCCCCHHHHHHHHHHHHHHHCCCCCCEEECCHHHHEECCCCCCCCCCCCCEEEEEEEHHH
SQAQSLGYTVVDASTVVATHLNQILYKHSHELIGHEEVQQLMQLLAKSSPKLAEELVPGV
HHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHH
LSLSSLLNVLQALLAEHVPVRDIRSIAEAIANNAGKSQDTAALVAAVRVGLSRAIVQSIV
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GVEPELPVITLEPRLEQILLNSLQKAGQGQEEGVLLEPSMAEKLQRSLIEAAQRQEMQGL
CCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHCCC
PVILLVAGPVRAMLSRFGRLAVPNMHVLAYQEIPDNKQVTIVATVGPNG
CEEEEECCHHHHHHHHCCCCCCCCEEEEEEECCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]