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The map label for this gene is gntK [H]

Identifier: 66046566

GI number: 66046566

Start: 3992589

End: 3993116

Strand: Direct

Name: gntK [H]

Synonym: Psyr_3337

Alternate gene names: 66046566

Gene position: 3992589-3993116 (Clockwise)

Preceding gene: 66046563

Following gene: 66046567

Centisome position: 65.52

GC content: 62.69

Gene sequence:

>528_bases
GTGACAACTGCGAATACTGCTATTTCCGCCCTTGTGGTGATGGGTGTGTCTGGCTGCGGCAAGAGCGCCGTGGGTGCCGA
GATCGCGCTGAACAGCGGCGGCCGCCTGATCGAAGGCGATGCGTTCCACCCACCGGCCAACATCGAAAAGATGAGCGCCG
GAACCCCCCTCAACGACGAAGACCGTGCCGGCTGGCTGACCCGCCTGGGCGAAGAGATGGCTGCAGCCCTCGCCAAGGGT
GAACACCCGGTCCTGACCTGCTCCTCGCTCAAGCTCATCTATCGCCAGCGCCTGCGTGATGCGGTGCCTGGCCTGGGTTT
TGTATTTCTGGAACTCAGCAAGGAACTCGCCGCCGAACGTTGCTCGCACCGGCCTGGACACTTCATGCCCGCCAGCCTGG
TGGACAGCCAGTTCGCGACCCTCGAACCGCCTTATGGCGAACCGCTGACATTGATCGTGGACGCCTCCCAGCCTATCGAT
GTCATCGGCAAACAAGCCGCAGCATGGTGGAAAGGCTCTCACGCCTGA

Upstream 100 bases:

>100_bases
TTGATGAGCCCAAAACAACGACAAATAACTGGAACAGCCCGGGCTGAGACTCATGTCCACCCGCAAGAAGACAGCGCTGT
CTCCAGATGAGGTGCCTACT

Downstream 100 bases:

>100_bases
CACAGGCATGAGTGCAAAAGACAGCGCTGTCTTGCGCACACACGATTGAAGTCGGCGCTGTTAGGCTTTGTACGAAAAGT
CGGCGAGCGAAGGTCAGGCA

Product: carbohydrate kinase, thermoresistant glucokinase

Products: NA

Alternate protein names: Gluconate kinase 2 [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MTTANTAISALVVMGVSGCGKSAVGAEIALNSGGRLIEGDAFHPPANIEKMSAGTPLNDEDRAGWLTRLGEEMAAALAKG
EHPVLTCSSLKLIYRQRLRDAVPGLGFVFLELSKELAAERCSHRPGHFMPASLVDSQFATLEPPYGEPLTLIVDASQPID
VIGKQAAAWWKGSHA

Sequences:

>Translated_175_residues
MTTANTAISALVVMGVSGCGKSAVGAEIALNSGGRLIEGDAFHPPANIEKMSAGTPLNDEDRAGWLTRLGEEMAAALAKG
EHPVLTCSSLKLIYRQRLRDAVPGLGFVFLELSKELAAERCSHRPGHFMPASLVDSQFATLEPPYGEPLTLIVDASQPID
VIGKQAAAWWKGSHA
>Mature_174_residues
TTANTAISALVVMGVSGCGKSAVGAEIALNSGGRLIEGDAFHPPANIEKMSAGTPLNDEDRAGWLTRLGEEMAAALAKGE
HPVLTCSSLKLIYRQRLRDAVPGLGFVFLELSKELAAERCSHRPGHFMPASLVDSQFATLEPPYGEPLTLIVDASQPIDV
IGKQAAAWWKGSHA

Specific function: Gluconate utilization system GNT-I. [C]

COG id: COG3265

COG function: function code G; Gluconate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gluconokinase gntK/gntV family [H]

Homologues:

Organism=Homo sapiens, GI299758445, Length=153, Percent_Identity=41.8300653594771, Blast_Score=110, Evalue=7e-25,
Organism=Escherichia coli, GI87082265, Length=161, Percent_Identity=40.3726708074534, Blast_Score=126, Evalue=8e-31,
Organism=Escherichia coli, GI1790719, Length=157, Percent_Identity=39.4904458598726, Blast_Score=124, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI25146487, Length=173, Percent_Identity=42.1965317919075, Blast_Score=126, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6320454, Length=146, Percent_Identity=41.0958904109589, Blast_Score=111, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR006001 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 18492; Mature: 18361

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTANTAISALVVMGVSGCGKSAVGAEIALNSGGRLIEGDAFHPPANIEKMSAGTPLNDE
CCCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCHHHCCCCCCCCC
DRAGWLTRLGEEMAAALAKGEHPVLTCSSLKLIYRQRLRDAVPGLGFVFLELSKELAAER
HHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
CSHRPGHFMPASLVDSQFATLEPPYGEPLTLIVDASQPIDVIGKQAAAWWKGSHA
HCCCCCCCCCHHHHCCCHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TTANTAISALVVMGVSGCGKSAVGAEIALNSGGRLIEGDAFHPPANIEKMSAGTPLNDE
CCCHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCHHHCCCCCCCCC
DRAGWLTRLGEEMAAALAKGEHPVLTCSSLKLIYRQRLRDAVPGLGFVFLELSKELAAER
HHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
CSHRPGHFMPASLVDSQFATLEPPYGEPLTLIVDASQPIDVIGKQAAAWWKGSHA
HCCCCCCCCCHHHHCCCHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9135111; 9278503; 8655507; 11468405 [H]