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The map label for this gene is lpsI [H]

Identifier: 66046466

GI number: 66046466

Start: 3875627

End: 3876328

Strand: Direct

Name: lpsI [H]

Synonym: Psyr_3237

Alternate gene names: 66046466

Gene position: 3875627-3876328 (Clockwise)

Preceding gene: 66046462

Following gene: 66046467

Centisome position: 63.6

GC content: 60.4

Gene sequence:

>702_bases
ATGGCTGGACTCGATAAACGAGTAGCGACCTACGAAGAAGCCCTCGCCGGGCTGACCGACGACATGACGGTACTCTGCGG
CGGCTTCGGCCTGTGCGGCATCCCGGAAAATCTCATCGCGCAGATCAGGCGCATGGGCATCAAGGGCCTGACCGTGGTCT
CCAACAACTGCGGCGTTGACGGCTTCGGACTCGGCATCCTGCTTGAGGACCGGCAGATCCGGAAAATGATTTCGTCCTAC
GTCGGCGAGAATGCCTTGTTCGAAAAGCAGTTGCTCAGCGGCGAGCTGGAAGTCGAACTCACTCCACAAGGCACTCTGGC
GGAGAAACTGCGCGCCGGCGGCGCGGGCATTCCGGCGTTCTATACCGCCACCGGTTACGGAACGCCGGTCGCCGAAGGCA
AGGAAACCCGCCAGTTCAACGGCCGCAACGTGATTCTGGAAGAGGCCATCACCGGTGACTTCGCCTTGATCAAGGGCTGG
AAAGCCGACCACTTCGGCAATGTCATCTATCGTCATACCGCACAGAACTTCAACCCGGTGGTGGCCACCGCCGGACGGAT
CACCGTGGTCGAGGTCGAGGAAATCGTCGAACCCGGCGTGCTGCTGCCGACCCAGATCCACACCCCCGGCATCTACGTCG
ACCGGGTCATACAGGGCACTTTCGAAAAACGCATCGAACAACGCACCGTCAGAAAATCCTGA

Upstream 100 bases:

>100_bases
AAAACAAAATTAACAAATCAGTCGCACCGAGAGAAGATGCAGGTCACCCGATCCTCCGGCAGCGCGACTGCCGGTCAACA
ACTATAAAAGGCGGATCATC

Downstream 100 bases:

>100_bases
TAGCGCAGCCTTGGCCCTACAACAATAAAGAGGCTTCAGACGATGGCACTTTCCCGCGAACAAATGGCTCAACGCGTCGC
CCGTGAACTCAAGGACGGTT

Product: 3-oxoacid CoA-transferase

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MAGLDKRVATYEEALAGLTDDMTVLCGGFGLCGIPENLIAQIRRMGIKGLTVVSNNCGVDGFGLGILLEDRQIRKMISSY
VGENALFEKQLLSGELEVELTPQGTLAEKLRAGGAGIPAFYTATGYGTPVAEGKETRQFNGRNVILEEAITGDFALIKGW
KADHFGNVIYRHTAQNFNPVVATAGRITVVEVEEIVEPGVLLPTQIHTPGIYVDRVIQGTFEKRIEQRTVRKS

Sequences:

>Translated_233_residues
MAGLDKRVATYEEALAGLTDDMTVLCGGFGLCGIPENLIAQIRRMGIKGLTVVSNNCGVDGFGLGILLEDRQIRKMISSY
VGENALFEKQLLSGELEVELTPQGTLAEKLRAGGAGIPAFYTATGYGTPVAEGKETRQFNGRNVILEEAITGDFALIKGW
KADHFGNVIYRHTAQNFNPVVATAGRITVVEVEEIVEPGVLLPTQIHTPGIYVDRVIQGTFEKRIEQRTVRKS
>Mature_232_residues
AGLDKRVATYEEALAGLTDDMTVLCGGFGLCGIPENLIAQIRRMGIKGLTVVSNNCGVDGFGLGILLEDRQIRKMISSYV
GENALFEKQLLSGELEVELTPQGTLAEKLRAGGAGIPAFYTATGYGTPVAEGKETRQFNGRNVILEEAITGDFALIKGWK
ADHFGNVIYRHTAQNFNPVVATAGRITVVEVEEIVEPGVLLPTQIHTPGIYVDRVIQGTFEKRIEQRTVRKS

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=239, Percent_Identity=61.0878661087866, Blast_Score=289, Evalue=2e-78,
Organism=Homo sapiens, GI11545841, Length=239, Percent_Identity=56.9037656903766, Blast_Score=251, Evalue=4e-67,
Organism=Escherichia coli, GI1788551, Length=214, Percent_Identity=39.7196261682243, Blast_Score=173, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17531517, Length=239, Percent_Identity=57.3221757322176, Blast_Score=276, Evalue=7e-75,
Organism=Drosophila melanogaster, GI21358325, Length=234, Percent_Identity=50.8547008547009, Blast_Score=239, Evalue=9e-64,
Organism=Drosophila melanogaster, GI24655794, Length=234, Percent_Identity=50.8547008547009, Blast_Score=239, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25267; Mature: 25136

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGLDKRVATYEEALAGLTDDMTVLCGGFGLCGIPENLIAQIRRMGIKGLTVVSNNCGVD
CCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCC
GFGLGILLEDRQIRKMISSYVGENALFEKQLLSGELEVELTPQGTLAEKLRAGGAGIPAF
CEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCEE
YTATGYGTPVAEGKETRQFNGRNVILEEAITGDFALIKGWKADHFGNVIYRHTAQNFNPV
EEECCCCCCCCCCCCHHHCCCCEEEEEHHCCCCEEEEECCCCCHHCCEEEEECCCCCCCE
VATAGRITVVEVEEIVEPGVLLPTQIHTPGIYVDRVIQGTFEKRIEQRTVRKS
EEECCCEEEEEHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AGLDKRVATYEEALAGLTDDMTVLCGGFGLCGIPENLIAQIRRMGIKGLTVVSNNCGVD
CCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCC
GFGLGILLEDRQIRKMISSYVGENALFEKQLLSGELEVELTPQGTLAEKLRAGGAGIPAF
CEEEEEEECCHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCEE
YTATGYGTPVAEGKETRQFNGRNVILEEAITGDFALIKGWKADHFGNVIYRHTAQNFNPV
EEECCCCCCCCCCCCHHHCCCCEEEEEHHCCCCEEEEECCCCCHHCCEEEEECCCCCCCE
VATAGRITVVEVEEIVEPGVLLPTQIHTPGIYVDRVIQGTFEKRIEQRTVRKS
EEECCCEEEEEHHHHHCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]