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The map label for this gene is lpsJ [H]

Identifier: 66046467

GI number: 66046467

Start: 3876371

End: 3877027

Strand: Direct

Name: lpsJ [H]

Synonym: Psyr_3238

Alternate gene names: 66046467

Gene position: 3876371-3877027 (Clockwise)

Preceding gene: 66046466

Following gene: 66046468

Centisome position: 63.61

GC content: 60.27

Gene sequence:

>657_bases
ATGGCACTTTCCCGCGAACAAATGGCTCAACGCGTCGCCCGTGAACTCAAGGACGGTTATTACGTGAACCTTGGCATCGG
CATTCCAACCCTGGTGGCCAACTATGTACCCGATGACATCGACGTCATGCTCCAGTCGGAAAACGGCCTGCTGGGCATGG
GCGCCTTCCCGACCGAAGACACCATCGACGCGGACATGATCAATGCCGGCAAGCAGACGGTCACCGCGCGCATTGGCGCC
TCCATTTTCTCGTCGGCCGAATCCTTTGCCATGATCCGCGGCGGCCATGTCGACCTGACAGTACTCGGCGCTTTCGAGGT
GGATATCGAGGGCAACATCGCTTCGTGGATGATCCCCGGCAAGCTGATCAAGGGCATGGGTGGCGCGATGGACCTGGTGG
CGGGCGCCGACAACATCATCGTCACCATGACCCATGCGTCGAAGGACGGCGAATCCAAGCTGCTCACCCGTTGCAGCCTG
CCACTGACCGGCGCAGGCTGCATCCGCAAGGTGCTGACTGATCTGGCCTACCTGGAAATCGAAAACGGCGCGTTCATCCT
CCGCGAACGCGCGCCGGGGGTCAGCGTGGAAGAAATCGTGGCCAAAACCGCAGGCAAGCTGATCGTGCCGGATGACGTGA
TCGAGATGAGTTTCTGA

Upstream 100 bases:

>100_bases
GGTCATACAGGGCACTTTCGAAAAACGCATCGAACAACGCACCGTCAGAAAATCCTGATAGCGCAGCCTTGGCCCTACAA
CAATAAAGAGGCTTCAGACG

Downstream 100 bases:

>100_bases
GTGCGGACATCCTTGATGCGTCTCTCGTTGCCACACGCCCGTGTGGCCTGCGTAACGGTGTGACGCGGAGCGTCACGAAC
TGCATTCCCACGCGGAGCAT

Product: 3-oxoacid CoA-transferase

Products: NA

Alternate protein names: OXCT B; Succinyl CoA:3-oxoacid CoA-transferase [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MALSREQMAQRVARELKDGYYVNLGIGIPTLVANYVPDDIDVMLQSENGLLGMGAFPTEDTIDADMINAGKQTVTARIGA
SIFSSAESFAMIRGGHVDLTVLGAFEVDIEGNIASWMIPGKLIKGMGGAMDLVAGADNIIVTMTHASKDGESKLLTRCSL
PLTGAGCIRKVLTDLAYLEIENGAFILRERAPGVSVEEIVAKTAGKLIVPDDVIEMSF

Sequences:

>Translated_218_residues
MALSREQMAQRVARELKDGYYVNLGIGIPTLVANYVPDDIDVMLQSENGLLGMGAFPTEDTIDADMINAGKQTVTARIGA
SIFSSAESFAMIRGGHVDLTVLGAFEVDIEGNIASWMIPGKLIKGMGGAMDLVAGADNIIVTMTHASKDGESKLLTRCSL
PLTGAGCIRKVLTDLAYLEIENGAFILRERAPGVSVEEIVAKTAGKLIVPDDVIEMSF
>Mature_217_residues
ALSREQMAQRVARELKDGYYVNLGIGIPTLVANYVPDDIDVMLQSENGLLGMGAFPTEDTIDADMINAGKQTVTARIGAS
IFSSAESFAMIRGGHVDLTVLGAFEVDIEGNIASWMIPGKLIKGMGGAMDLVAGADNIIVTMTHASKDGESKLLTRCSLP
LTGAGCIRKVLTDLAYLEIENGAFILRERAPGVSVEEIVAKTAGKLIVPDDVIEMSF

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=215, Percent_Identity=48.8372093023256, Blast_Score=216, Evalue=8e-57,
Organism=Homo sapiens, GI11545841, Length=216, Percent_Identity=47.2222222222222, Blast_Score=213, Evalue=8e-56,
Organism=Escherichia coli, GI1788552, Length=210, Percent_Identity=47.1428571428571, Blast_Score=206, Evalue=9e-55,
Organism=Caenorhabditis elegans, GI17531517, Length=216, Percent_Identity=51.8518518518518, Blast_Score=216, Evalue=5e-57,
Organism=Drosophila melanogaster, GI21358325, Length=214, Percent_Identity=55.1401869158878, Blast_Score=241, Evalue=3e-64,
Organism=Drosophila melanogaster, GI24655794, Length=214, Percent_Identity=55.1401869158878, Blast_Score=241, Evalue=4e-64,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012791
- InterPro:   IPR004165
- InterPro:   IPR004164 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 23165; Mature: 23034

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS01274 COA_TRANSF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALSREQMAQRVARELKDGYYVNLGIGIPTLVANYVPDDIDVMLQSENGLLGMGAFPTED
CCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCEEEEEECCCCEEEECCCCCCC
TIDADMINAGKQTVTARIGASIFSSAESFAMIRGGHVDLTVLGAFEVDIEGNIASWMIPG
CCCHHHHCCCCHHHHHHHHHHHHHCCHHEEEEECCCEEEEEEEEEEEEECCCEEEEECCH
KLIKGMGGAMDLVAGADNIIVTMTHASKDGESKLLTRCSLPLTGAGCIRKVLTDLAYLEI
HHHHCCCCHHHHHCCCCCEEEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHEEEE
ENGAFILRERAPGVSVEEIVAKTAGKLIVPDDVIEMSF
CCCEEEEEECCCCCCHHHHHHHHCCCEECCCHHHCCCC
>Mature Secondary Structure 
ALSREQMAQRVARELKDGYYVNLGIGIPTLVANYVPDDIDVMLQSENGLLGMGAFPTED
CCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCEEEEEECCCCEEEECCCCCCC
TIDADMINAGKQTVTARIGASIFSSAESFAMIRGGHVDLTVLGAFEVDIEGNIASWMIPG
CCCHHHHCCCCHHHHHHHHHHHHHCCHHEEEEECCCEEEEEEEEEEEEECCCEEEEECCH
KLIKGMGGAMDLVAGADNIIVTMTHASKDGESKLLTRCSLPLTGAGCIRKVLTDLAYLEI
HHHHCCCCHHHHHCCCCCEEEEEEECCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHEEEE
ENGAFILRERAPGVSVEEIVAKTAGKLIVPDDVIEMSF
CCCEEEEEECCCCCCHHHHHHHHCCCEECCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134 [H]