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The map label for this gene is nuoE [H]

Identifier: 66046429

GI number: 66046429

Start: 3830663

End: 3831160

Strand: Direct

Name: nuoE [H]

Synonym: Psyr_3200

Alternate gene names: 66046429

Gene position: 3830663-3831160 (Clockwise)

Preceding gene: 66046428

Following gene: 66046430

Centisome position: 62.86

GC content: 60.44

Gene sequence:

>498_bases
ATGAATAGCCCGCTAATCCAGACTGACCGTTTCGCCCTGAGCGAAACCGAGCGCTCGGCCATCGAGCATGAGATGCATCA
CTACGAGGACCCGCGCGCGGCGTCCATCGAAGCCCTGAAAATTGTTCAGAAGGAACGTGGCTGGGTGCCTGACGGTGCCA
TTTACGCGATCGGCGACCTGCTGGGCATCCCCGCCAGCGACGTCGAAGGCGTTGCCACCTTCTACAGCCAGATCTTTCGC
CAGCCGGTCGGGCGTCACATCATTCGTGTCTGTAACAGCATGGTGTGTTTCATCGGCGGCCACGAAAACGTGGTCGACGA
GATCAAGAACTCACTGGGCATCGGCCTGGGCCAGACCACCGCCGACGGTCGTTTCACACTGCTGCCGGTCTGCTGCCTCG
GCAACTGTGACAAGGCGCCGGCCGTGATGGTCGACGACGACACTTTCGGCGATGTACAGCCTGCTGGCGTTGCCAAGATG
CTGGAGGGTTACCTATGA

Upstream 100 bases:

>100_bases
TGCAGCAGATCCCTTCGGTGATCAAAGGCAGCATGGTCGCGGACTTGATCGCGTACCTGGGTAGTATCGATTTCGTTATG
GCCGACGTGGACCGCTAAGC

Downstream 100 bases:

>100_bases
CCATCACTTCCTTCGGCCCTGCCAACCGCATTGCGCGCACGGCAGAAACCCATCCGCTGACCTGGCGTCTGCGCGACGAC
GGCGAACCGGTCTGGCTCGA

Product: NADH dehydrogenase subunit E

Products: NA

Alternate protein names: NADH dehydrogenase I subunit E; NDH-1 subunit E [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MNSPLIQTDRFALSETERSAIEHEMHHYEDPRAASIEALKIVQKERGWVPDGAIYAIGDLLGIPASDVEGVATFYSQIFR
QPVGRHIIRVCNSMVCFIGGHENVVDEIKNSLGIGLGQTTADGRFTLLPVCCLGNCDKAPAVMVDDDTFGDVQPAGVAKM
LEGYL

Sequences:

>Translated_165_residues
MNSPLIQTDRFALSETERSAIEHEMHHYEDPRAASIEALKIVQKERGWVPDGAIYAIGDLLGIPASDVEGVATFYSQIFR
QPVGRHIIRVCNSMVCFIGGHENVVDEIKNSLGIGLGQTTADGRFTLLPVCCLGNCDKAPAVMVDDDTFGDVQPAGVAKM
LEGYL
>Mature_165_residues
MNSPLIQTDRFALSETERSAIEHEMHHYEDPRAASIEALKIVQKERGWVPDGAIYAIGDLLGIPASDVEGVATFYSQIFR
QPVGRHIIRVCNSMVCFIGGHENVVDEIKNSLGIGLGQTTADGRFTLLPVCCLGNCDKAPAVMVDDDTFGDVQPAGVAKM
LEGYL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=130, Percent_Identity=34.6153846153846, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI1788621, Length=158, Percent_Identity=68.9873417721519, Blast_Score=239, Evalue=7e-65,
Organism=Caenorhabditis elegans, GI17561328, Length=155, Percent_Identity=35.4838709677419, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI18859877, Length=153, Percent_Identity=33.3333333333333, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21355353, Length=154, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 17935; Mature: 17935

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS01099 COMPLEX1_24K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSPLIQTDRFALSETERSAIEHEMHHYEDPRAASIEALKIVQKERGWVPDGAIYAIGDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LGIPASDVEGVATFYSQIFRQPVGRHIIRVCNSMVCFIGGHENVVDEIKNSLGIGLGQTT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHCCCCCCCC
ADGRFTLLPVCCLGNCDKAPAVMVDDDTFGDVQPAGVAKMLEGYL
CCCCEEEEHEECCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNSPLIQTDRFALSETERSAIEHEMHHYEDPRAASIEALKIVQKERGWVPDGAIYAIGDL
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHH
LGIPASDVEGVATFYSQIFRQPVGRHIIRVCNSMVCFIGGHENVVDEIKNSLGIGLGQTT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHCCCCCCCC
ADGRFTLLPVCCLGNCDKAPAVMVDDDTFGDVQPAGVAKMLEGYL
CCCCEEEEHEECCCCCCCCCEEEECCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]