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The map label for this gene is mdtA [H]

Identifier: 66046360

GI number: 66046360

Start: 3754317

End: 3755408

Strand: Direct

Name: mdtA [H]

Synonym: Psyr_3131

Alternate gene names: 66046360

Gene position: 3754317-3755408 (Clockwise)

Preceding gene: 66046359

Following gene: 66046361

Centisome position: 61.61

GC content: 63.0

Gene sequence:

>1092_bases
ATGAGCACCTCGTACGCAGAAACACGAACCAGATCCCGCTGCTGGCTGATCTGCATTCTGATCGTGGCTCTGCCGGGCTG
CCGCGACAAACCGCTTCGCGAGGTTGTCGAACGCCCGGTACTGTTCACCGAAATAGTCGATCAGCGCAGCGCCTCTCATG
GCCGCTTCGCCGGCGTCATTCAGCCGCAGTATGAAGTGGCATTGGGGTTTCGCGTCGCAGGGCGACTGGCAAGCCGGCAT
GCGGAGATCGGTGATCGGGTGCGCAAGGGCGATCTGCTCGCCACGCTGGAACCCGGCGACCAGCAACACCGTTTGCGTGC
CCGCCAGGCAGAACTCGGCAAAGCCCAATCCGCCTGGCAACAGGCACGCGATGAATTGACGCGCTACCAGCAACTCTATG
AGCGCGGTATCGGCTCGCGAGCGCGAATGGATCAGCTGGACAACGACCTGCGCACTCAGGACGCGCTGCGCAATCAGGCC
CGCGTCGCGGTGCAGCAAGCCGGTGATCATGTGTCCTACACACATTTGTCAGCCGAGTTCGATGGCCTGATCACAGGATG
GCAAGCCGAAGTCGGCCAGGTCATGGCGACCGGTCAGGCAGTGGTCAGTCTTGCGCGCCCGGACAGCCGTGAAGCGGTCG
TCGACTTGCCACTCGGTTCGCTGGATGAACGCCACCGCATCAGAGTGATTTCGCAAATCAACGAACAGCTTTCAGTGGCC
GCGGACGTCCGCCAGCTTGCGCCGCAAATCAATGCCGAGACCCGCACTCAGCGCGTCCGCCTGGCCTTGCAGAACCCTGC
GGACAGCTTTCGCCTGGGCTCGACCGTCACGGTAGAGATCAGTGGCGACGCGCCGGCGTTTCATGAGCTGCCCGGCAGCG
CAGTGCTGCAGCGTGACGGCACGTATCAGGTGTGGGTGATCGACCCAACGACATCGACACTGGTCCCGCGCGCGGTGCAG
GTACTGGCGCGATCAGGCTCGACGGTAAGGGTCAGCGGCGCGCTGCACGAGGGCGAAAAAGTAGTGACTGCCGGAGTCAA
CGGCATGCAGTCCGGACAGAAGATCCGCCTGCAGCGAGAGGTCAGTTTGTGA

Upstream 100 bases:

>100_bases
CCCGGGGGCTGCAGTTTCTCTACCCGGGGCAACGGGTAGAGGTCGCAGGGCAAGCGCAAGCCGAACAAAGCGTCTCGCTG
GCGTCATCGGGAGCTGCGCA

Downstream 100 bases:

>100_bases
AGGAGCGCTTCAATCTGTCGGCCTGGGGGCTCAGGCATCGCACGCTGGTCTGGTACATGATGTTCGTTTCACTGCTGATG
GGCAGCTGGTCATTCCTGAA

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSTSYAETRTRSRCWLICILIVALPGCRDKPLREVVERPVLFTEIVDQRSASHGRFAGVIQPQYEVALGFRVAGRLASRH
AEIGDRVRKGDLLATLEPGDQQHRLRARQAELGKAQSAWQQARDELTRYQQLYERGIGSRARMDQLDNDLRTQDALRNQA
RVAVQQAGDHVSYTHLSAEFDGLITGWQAEVGQVMATGQAVVSLARPDSREAVVDLPLGSLDERHRIRVISQINEQLSVA
ADVRQLAPQINAETRTQRVRLALQNPADSFRLGSTVTVEISGDAPAFHELPGSAVLQRDGTYQVWVIDPTTSTLVPRAVQ
VLARSGSTVRVSGALHEGEKVVTAGVNGMQSGQKIRLQREVSL

Sequences:

>Translated_363_residues
MSTSYAETRTRSRCWLICILIVALPGCRDKPLREVVERPVLFTEIVDQRSASHGRFAGVIQPQYEVALGFRVAGRLASRH
AEIGDRVRKGDLLATLEPGDQQHRLRARQAELGKAQSAWQQARDELTRYQQLYERGIGSRARMDQLDNDLRTQDALRNQA
RVAVQQAGDHVSYTHLSAEFDGLITGWQAEVGQVMATGQAVVSLARPDSREAVVDLPLGSLDERHRIRVISQINEQLSVA
ADVRQLAPQINAETRTQRVRLALQNPADSFRLGSTVTVEISGDAPAFHELPGSAVLQRDGTYQVWVIDPTTSTLVPRAVQ
VLARSGSTVRVSGALHEGEKVVTAGVNGMQSGQKIRLQREVSL
>Mature_362_residues
STSYAETRTRSRCWLICILIVALPGCRDKPLREVVERPVLFTEIVDQRSASHGRFAGVIQPQYEVALGFRVAGRLASRHA
EIGDRVRKGDLLATLEPGDQQHRLRARQAELGKAQSAWQQARDELTRYQQLYERGIGSRARMDQLDNDLRTQDALRNQAR
VAVQQAGDHVSYTHLSAEFDGLITGWQAEVGQVMATGQAVVSLARPDSREAVVDLPLGSLDERHRIRVISQINEQLSVAA
DVRQLAPQINAETRTQRVRLALQNPADSFRLGSTVTVEISGDAPAFHELPGSAVLQRDGTYQVWVIDPTTSTLVPRAVQV
LARSGSTVRVSGALHEGEKVVTAGVNGMQSGQKIRLQREVSL

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=348, Percent_Identity=23.5632183908046, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40045; Mature: 39914

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSYAETRTRSRCWLICILIVALPGCRDKPLREVVERPVLFTEIVDQRSASHGRFAGVI
CCCCCHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCEEEEE
QPQYEVALGFRVAGRLASRHAEIGDRVRKGDLLATLEPGDQQHRLRARQAELGKAQSAWQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
QARDELTRYQQLYERGIGSRARMDQLDNDLRTQDALRNQARVAVQQAGDHVSYTHLSAEF
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHH
DGLITGWQAEVGQVMATGQAVVSLARPDSREAVVDLPLGSLDERHRIRVISQINEQLSVA
CCCEECHHHHHHHHHHHHHHHHEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
ADVRQLAPQINAETRTQRVRLALQNPADSFRLGSTVTVEISGDAPAFHELPGSAVLQRDG
HHHHHHHHCCCCHHHHHHHHEEECCCCCCEECCCEEEEEECCCCCHHHHCCCCCEEECCC
TYQVWVIDPTTSTLVPRAVQVLARSGSTVRVSGALHEGEKVVTAGVNGMQSGQKIRLQRE
CEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCCCCEEEEEEC
VSL
CCC
>Mature Secondary Structure 
STSYAETRTRSRCWLICILIVALPGCRDKPLREVVERPVLFTEIVDQRSASHGRFAGVI
CCCCHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCEEEEE
QPQYEVALGFRVAGRLASRHAEIGDRVRKGDLLATLEPGDQQHRLRARQAELGKAQSAWQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHH
QARDELTRYQQLYERGIGSRARMDQLDNDLRTQDALRNQARVAVQQAGDHVSYTHLSAEF
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHH
DGLITGWQAEVGQVMATGQAVVSLARPDSREAVVDLPLGSLDERHRIRVISQINEQLSVA
CCCEECHHHHHHHHHHHHHHHHEECCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHH
ADVRQLAPQINAETRTQRVRLALQNPADSFRLGSTVTVEISGDAPAFHELPGSAVLQRDG
HHHHHHHHCCCCHHHHHHHHEEECCCCCCEECCCEEEEEECCCCCHHHHCCCCCEEECCC
TYQVWVIDPTTSTLVPRAVQVLARSGSTVRVSGALHEGEKVVTAGVNGMQSGQKIRLQRE
CEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCCCCCCCCEEEEEEC
VSL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]