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The map label for this gene is mdtA [H]

Identifier: 66046359

GI number: 66046359

Start: 3753133

End: 3754320

Strand: Direct

Name: mdtA [H]

Synonym: Psyr_3130

Alternate gene names: 66046359

Gene position: 3753133-3754320 (Clockwise)

Preceding gene: 66046358

Following gene: 66046360

Centisome position: 61.59

GC content: 62.71

Gene sequence:

>1188_bases
ATGACTTTTTCCTTTGCAACGCTCCTGCGTTCGTGCTGCCGTGTTTCCGGAAATATCCGGCCGTTGCACTCCCTGTACGC
CCAGCCCCATGTGGTACTGGGTTTCATCTCGCTACTGTCACTCAGCGCCTGTTCTGCAGGAAAACCCGCAGAAAAGGCGC
TGGTGCGAGTCAGCGCGCAACCGGTTGCCTTACTGAACGTTGCCAGCAGTGTGACGCTGACGGGCGATATCCAGGCTCGC
AAGGTGACCGAGCAATCGTTTCGTGTCTCCGGCAAGCTGATCAAGCGCTACGTGGATGTCGGGGATCGAGTGCGGGTCGG
ACAGGTGCTGGCCAGACTCGACGCACGCGAGCAAAACACCGAGCTGGCGTCAGCCCGTACCGAAGTCGCGGTACGACAGT
CGCGGCTGCACCTCGCCGAACAGAACTACCAGCGGCAGCAAGTGCTGCTGCCCAAGGGTTTTACCAACCTCAGTGAATAC
CAGAAGGCCCGCTCCGGCCTCGACAGTGCGCGGGGGGATCTCGCCGCGCTGCAGGCGCAGCAGGCCAATGCGCGTGACCA
GGTCGGTTATACCGGGCTGTTCGCAGCAGCCGATGGCATCGTGACGGCGCGGTATGCCGAAGAAGGTCAGGTGGTTCAGG
CCGCCACTGCGATTTTCAGCGTCGCCCACGATGGCGAGCGCGAAGCGGTATTTTCCGCGTATGAATCACTGCTGCGAGCC
GATCAGAAAGGTGCCGCAGTGACTGTCAGCCCCTTGGGCCAGCCAGGGACTCAGTTGACCGGCATCATCAGGGAAATCAC
CCCTATCGTCTCCGCTGCAAATGGCACGTTGCGAGTGCGCGTTGCTCTGCAGGGCGCCGCTGCGTCGCTCGCGCTGGGCT
CCGTGGTCAGCGCTCGCTTGCAGACGCAGTCGCAATCGGCGTTCGCCCTGCCCTGGTCCGCCTTGAGCCGCACACAAGGA
CAACCGGCAGTCTGGCGGGTGGACGCCCAGGCCAGGGTCAGGCTGACGCCTGTCAAAGTGCTGCGTTACGAACAGGGTCA
GGTCATCGTTTCAGAAGGGCTGTCCGAAGGTGATCGGGTGGTGTCCCGGGGGCTGCAGTTTCTCTACCCGGGGCAACGGG
TAGAGGTCGCAGGGCAAGCGCAAGCCGAACAAAGCGTCTCGCTGGCGTCATCGGGAGCTGCGCAATGA

Upstream 100 bases:

>100_bases
TGAAGCACTCGCCTGCGCCCGGGAAGCCCTTGCGCTTTTCCGGCGTGACGCTGTGATTCATGGGTGTTGGCTTTCTTTGA
TCGGGCAGTGCTATTCGTTG

Downstream 100 bases:

>100_bases
GCACCTCGTACGCAGAAACACGAACCAGATCCCGCTGCTGGCTGATCTGCATTCTGATCGTGGCTCTGCCGGGCTGCCGC
GACAAACCGCTTCGCGAGGT

Product: secretion protein HlyD

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MTFSFATLLRSCCRVSGNIRPLHSLYAQPHVVLGFISLLSLSACSAGKPAEKALVRVSAQPVALLNVASSVTLTGDIQAR
KVTEQSFRVSGKLIKRYVDVGDRVRVGQVLARLDAREQNTELASARTEVAVRQSRLHLAEQNYQRQQVLLPKGFTNLSEY
QKARSGLDSARGDLAALQAQQANARDQVGYTGLFAAADGIVTARYAEEGQVVQAATAIFSVAHDGEREAVFSAYESLLRA
DQKGAAVTVSPLGQPGTQLTGIIREITPIVSAANGTLRVRVALQGAAASLALGSVVSARLQTQSQSAFALPWSALSRTQG
QPAVWRVDAQARVRLTPVKVLRYEQGQVIVSEGLSEGDRVVSRGLQFLYPGQRVEVAGQAQAEQSVSLASSGAAQ

Sequences:

>Translated_395_residues
MTFSFATLLRSCCRVSGNIRPLHSLYAQPHVVLGFISLLSLSACSAGKPAEKALVRVSAQPVALLNVASSVTLTGDIQAR
KVTEQSFRVSGKLIKRYVDVGDRVRVGQVLARLDAREQNTELASARTEVAVRQSRLHLAEQNYQRQQVLLPKGFTNLSEY
QKARSGLDSARGDLAALQAQQANARDQVGYTGLFAAADGIVTARYAEEGQVVQAATAIFSVAHDGEREAVFSAYESLLRA
DQKGAAVTVSPLGQPGTQLTGIIREITPIVSAANGTLRVRVALQGAAASLALGSVVSARLQTQSQSAFALPWSALSRTQG
QPAVWRVDAQARVRLTPVKVLRYEQGQVIVSEGLSEGDRVVSRGLQFLYPGQRVEVAGQAQAEQSVSLASSGAAQ
>Mature_394_residues
TFSFATLLRSCCRVSGNIRPLHSLYAQPHVVLGFISLLSLSACSAGKPAEKALVRVSAQPVALLNVASSVTLTGDIQARK
VTEQSFRVSGKLIKRYVDVGDRVRVGQVLARLDAREQNTELASARTEVAVRQSRLHLAEQNYQRQQVLLPKGFTNLSEYQ
KARSGLDSARGDLAALQAQQANARDQVGYTGLFAAADGIVTARYAEEGQVVQAATAIFSVAHDGEREAVFSAYESLLRAD
QKGAAVTVSPLGQPGTQLTGIIREITPIVSAANGTLRVRVALQGAAASLALGSVVSARLQTQSQSAFALPWSALSRTQGQ
PAVWRVDAQARVRLTPVKVLRYEQGQVIVSEGLSEGDRVVSRGLQFLYPGQRVEVAGQAQAEQSVSLASSGAAQ

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=298, Percent_Identity=24.496644295302, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1789929, Length=359, Percent_Identity=25.6267409470752, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786668, Length=387, Percent_Identity=26.6149870801034, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42076; Mature: 41945

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFSFATLLRSCCRVSGNIRPLHSLYAQPHVVLGFISLLSLSACSAGKPAEKALVRVSAQ
CCCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHEEECCC
PVALLNVASSVTLTGDIQARKVTEQSFRVSGKLIKRYVDVGDRVRVGQVLARLDAREQNT
CEEEEEHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
ELASARTEVAVRQSRLHLAEQNYQRQQVLLPKGFTNLSEYQKARSGLDSARGDLAALQAQ
HHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCHHHHHHHHHCHHHHCCHHHHHHHH
QANARDQVGYTGLFAAADGIVTARYAEEGQVVQAATAIFSVAHDGEREAVFSAYESLLRA
HCCCCCCCCCCCHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
DQKGAAVTVSPLGQPGTQLTGIIREITPIVSAANGTLRVRVALQGAAASLALGSVVSARL
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHH
QTQSQSAFALPWSALSRTQGQPAVWRVDAQARVRLTPVKVLRYEQGQVIVSEGLSEGDRV
HHCCCCCEECCHHHHHCCCCCCCEEEECCCCEEEEEHHHEEEECCCCEEEECCCCCHHHH
VSRGLQFLYPGQRVEVAGQAQAEQSVSLASSGAAQ
HHHCHHHCCCCCEEEECCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TFSFATLLRSCCRVSGNIRPLHSLYAQPHVVLGFISLLSLSACSAGKPAEKALVRVSAQ
CCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHEEECCC
PVALLNVASSVTLTGDIQARKVTEQSFRVSGKLIKRYVDVGDRVRVGQVLARLDAREQNT
CEEEEEHHCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
ELASARTEVAVRQSRLHLAEQNYQRQQVLLPKGFTNLSEYQKARSGLDSARGDLAALQAQ
HHHHHHHHHHHHHHHHHHHHHCCCHHEEECCCCCCCHHHHHHHHHCHHHHCCHHHHHHHH
QANARDQVGYTGLFAAADGIVTARYAEEGQVVQAATAIFSVAHDGEREAVFSAYESLLRA
HCCCCCCCCCCCHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
DQKGAAVTVSPLGQPGTQLTGIIREITPIVSAANGTLRVRVALQGAAASLALGSVVSARL
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHH
QTQSQSAFALPWSALSRTQGQPAVWRVDAQARVRLTPVKVLRYEQGQVIVSEGLSEGDRV
HHCCCCCEECCHHHHHCCCCCCCEEEECCCCEEEEEHHHEEEECCCCEEEECCCCCHHHH
VSRGLQFLYPGQRVEVAGQAQAEQSVSLASSGAAQ
HHHCHHHCCCCCEEEECCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]