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The map label for this gene is nadR [C]

Identifier: 66046241

GI number: 66046241

Start: 3604250

End: 3604795

Strand: Direct

Name: nadR [C]

Synonym: Psyr_3010

Alternate gene names: 66046241

Gene position: 3604250-3604795 (Clockwise)

Preceding gene: 66046240

Following gene: 66046243

Centisome position: 59.15

GC content: 63.55

Gene sequence:

>546_bases
ATGAAAGTTCTGGTCCTCACCGGCCCCGAGTCCAGCGGCAAGAGCTGGCTGTCGGCGCAAATACAGCATAGGTTTGGCGG
CCTGCTGGTCGGCGAATACGTCCGGCAGTTCATCGATCAGCAGGGCCGCGATACCGATTACGCCGACATACCGGCCATCG
CCCGGGGCCAGCTGGCCTGGGAGGACGCCGCGCGCAGCGCCGAGCCAAACTTGCTGATACTCGACACGCACCTGTTGAGC
AACATGCTCTGGAGCCGCACCCTGTTCGGCGATTGCCCTGCGTGGATCGAACAGCAACTGCTGAGCCGATCCTATGACCT
GCACCTGCTGCTGTCGCCCGAAGGCGTTGACTGGATCAGCGACGGCCAGCGCTGCCAGCCGCAGTTGGGTGAACGCCAGG
CCTTTTTCGACGCCAGCCGGGAATGGCTGGAACACCACCTGCAGGCTTACCGGGTACTGGGCGGTAACTGGGAGCAGCGC
CGCGAACAGGCGCTGACCGCTGTCTCACAGTTGCTGGGCGACTCAGCGGATCTGGTGCTTGTGTAA

Upstream 100 bases:

>100_bases
TCTACAAGGAGCTGTACCTGACGGCTGCGCTGTATGGCTTGTTCACCCTGCTGGCGGTACAGGGCTGGCGCGAGTGGCGT
AACGATCTGGCGCTGGCGCG

Downstream 100 bases:

>100_bases
CAGCCGATAGAACGTTGGCCGCGAAATACCCAGCACTCTGGCCGCCACACTCAAATTGTCACTGTGGCGCGTCAACACGT
CGCACAACGCCTGACGCTCG

Product: nicotinamide-nucleotide adenylyltransferase, putative

Products: NAD; pyrophosphate [C]

Alternate protein names: ATPase/Kinase Involved In NAD Metabolism-Like Protein; ATPase/Kinase Involved In NAD Metabolism-Like; NADR-Like Protein

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MKVLVLTGPESSGKSWLSAQIQHRFGGLLVGEYVRQFIDQQGRDTDYADIPAIARGQLAWEDAARSAEPNLLILDTHLLS
NMLWSRTLFGDCPAWIEQQLLSRSYDLHLLLSPEGVDWISDGQRCQPQLGERQAFFDASREWLEHHLQAYRVLGGNWEQR
REQALTAVSQLLGDSADLVLV

Sequences:

>Translated_181_residues
MKVLVLTGPESSGKSWLSAQIQHRFGGLLVGEYVRQFIDQQGRDTDYADIPAIARGQLAWEDAARSAEPNLLILDTHLLS
NMLWSRTLFGDCPAWIEQQLLSRSYDLHLLLSPEGVDWISDGQRCQPQLGERQAFFDASREWLEHHLQAYRVLGGNWEQR
REQALTAVSQLLGDSADLVLV
>Mature_181_residues
MKVLVLTGPESSGKSWLSAQIQHRFGGLLVGEYVRQFIDQQGRDTDYADIPAIARGQLAWEDAARSAEPNLLILDTHLLS
NMLWSRTLFGDCPAWIEQQLLSRSYDLHLLLSPEGVDWISDGQRCQPQLGERQAFFDASREWLEHHLQAYRVLGGNWEQR
REQALTAVSQLLGDSADLVLV

Specific function: NADr Is Bifunctional; It Interacts With Pnuc At Low Internal NAD Levels, Permitting Transport Of Nmn Intact Into The Cell. As NAD Levels Increase Within The Cell, The Affinity Of NADr For The Operator Regions Of NADa, NADb, And Pncb Increases, Repressing

COG id: COG3172

COG function: function code H; Predicted ATPase/kinase involved in NAD metabolism

Gene ontology:

Cell location: May Loosely Associate With The Membrane Through Its Interaction With The Membrane-Bound Pnuc [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 20485; Mature: 20485

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVLVLTGPESSGKSWLSAQIQHRFGGLLVGEYVRQFIDQQGRDTDYADIPAIARGQLAW
CEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHH
EDAARSAEPNLLILDTHLLSNMLWSRTLFGDCPAWIEQQLLSRSYDLHLLLSPEGVDWIS
HHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHC
DGQRCQPQLGERQAFFDASREWLEHHLQAYRVLGGNWEQRREQALTAVSQLLGDSADLVL
CCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEE
V
C
>Mature Secondary Structure
MKVLVLTGPESSGKSWLSAQIQHRFGGLLVGEYVRQFIDQQGRDTDYADIPAIARGQLAW
CEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCCHHH
EDAARSAEPNLLILDTHLLSNMLWSRTLFGDCPAWIEQQLLSRSYDLHLLLSPEGVDWIS
HHHHCCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCCCCCHHC
DGQRCQPQLGERQAFFDASREWLEHHLQAYRVLGGNWEQRREQALTAVSQLLGDSADLVL
CCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCEEE
V
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide; ATP [C]

Specific reaction: nicotinamide nucleotide + ATP = NAD + pyrophosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA