Click here to switch to the map view.

The map label for this gene is tsr [C]

Identifier: 66046197

GI number: 66046197

Start: 3554136

End: 3556064

Strand: Reverse

Name: tsr [C]

Synonym: Psyr_2966

Alternate gene names: 66046197

Gene position: 3556064-3554136 (Counterclockwise)

Preceding gene: 66046203

Following gene: 66046182

Centisome position: 58.36

GC content: 58.89

Gene sequence:

>1929_bases
ATGAAGTCGACATGGCTGGACAATTTGAAGGTCAGCAAAAAGCTGAGTGTAGGCTTCGGTCTGATACTGCTGGGCGTACT
GACGGTCACCGCGATCGGTTACCTCAGTACCAACCTGCTGATCGAACGGCTGGGCAAGGCAGCCAAGGTTTCTGAGGTGA
AGGCCGATGCGCTGAGCCTCAGGATCGCTGCGCAGACCTACACCGCCAAGCCTGACGCGAGCAATTCGCAGGGCTACACG
TCGGCTCTGGACAACCTGGGCAAGACCATCGAGGACGGCCTGAAGATTCTGACCGTTCCGGTCAACGCCGATATGCTCAG
AGGGATTCGCGACCAGGCGGGTGTCTTGAAGCAAACGTTCAGCCAGTTGGTCGATAACAATCGGCAAATTGATCAGGCCA
TGCAGCCGCTCATCACTATTTCCGAACAGGTCAGCGGAAGTTTCGAAACACTGCTGCAAAAGACCTTTGACGACGTTTCC
CGCTCGCTGGACCAGAGCGGCATCGATCAGGTGAAGATTGCCGGCGACCTGCGCAATGGCATGACCAACTTTCGCCTGGT
GTTTCGCCGTTATATCAGTATCCCGACTGCTGAAAACAGGCAGATTACTTTCGACGCTGCCGACTCGCTGATCGCTCAGG
TGGGCAGCGCGCGCAATCAATTGCCGAACAAGGCCGGCCCGGCGGTGGATGAGGCGCTCGCGGCGCTGCAACAGTACAAG
TCGTTGATGGTCTCCATCTCGCAACTGATGCAACAGAACGATCAGATTCGCGACAGCCTTCGCCAGCAGTCAATGGACAT
CGTCACCAGTGCGGAAAAGCTGATGGCGGGTCAGGTGGTCAGCGCCAATAAAGAAAAAGACAGCGCAGTAACCCAGTTGC
TCACGGTGGCGGTGATCGTATTGCTGCTGGGTATCTTCGCGGCGATCCTGATTACCCGTCAGATCACCCGTCCGCTCGAT
TCGACTGTGATCGCGGCGCGTCGGATTGCCGACGGCGATCTGACCAACGACCTCAGCACCACTCGCCAGGATGAGCTGGG
CCTGCTGCAAAACACCATGCAACACATGACCGTATCGCTGCGGACCCTGATTGGCGGTATCAGCAATGGTGTGACACAGA
TTGCCACGGCAGCCGAGGAGCTTTCAGCCGTCAGTGAGCAGACCAGCGCGGGTGTTACTCAGCAGAAACTGGAAGTCGAT
CAGGTGGCGACCGCCATGAACCAGATGGCGTCCACCGTCCAGGAAGTGGCGCAGAACACTGAAGATGCATCGCAGGCCGC
CAGACAGGCCAGTGATCGTGCCGCCCATGGCAGCAGCGTGGTGCAACACGCCACGCGTGAAATCAGCCAGCTCGCCGGTG
AAGTGGGACAACTGGGCGAGGCCATGCAGCGCCTGATTCAGGACAGTGACAAGATCGGCGGCGTCATCGATGTGATCAAG
GCGGTGGCAGAACAAACCAACCTGCTGGCCCTCAATGCGGCGATCGAAGCTGCACGTGCAGGTGAGCAGGGCCGTGGCTT
TGCCGTGGTGGCCGATGAGGTGCGCTCGCTGGCTCAGCGTACACAGTCATCCACGACTGAAATCGAGGCGCTGATAAAGT
CCTTGCAGGATGGCACCGGCGCAGCGTCGGAGCTGATGAATGCCAGCCGTCAACGCACTGAAGGCACCGTGGCGCTGGCG
CGGCAGGCCGAAGAATCGCTGCTTGAAATCACTCATTCGATCGTGACCATCGAGCAGATGAGTCAACAGATCTCTGCTGC
CGCTGAAGAGCAGAGCGCCGTGACCGACGAAATCAATCGCAGTGTCATCAGCGTACGCGATATTGCCGATCAGTCGGCCA
CGGCCACTGAGCAGAGCGCGGCGTCTACCGTGGAACTGGCGCGCCTGGGCAGCAACCTGCAGGACATGGTTGCGCGCTTC
CGGATCTGA

Upstream 100 bases:

>100_bases
TTGCTATCTCGTCGATCAATCTTTGCAATCGCCGCGACTATTAAGTTGTTCCGCAGACAGTCGATCCTTGGGTATCACGA
TAAATCCCCAGGAAAAATTT

Downstream 100 bases:

>100_bases
TGGTCGCCACTTTCAAATCGTTGCGAAGTTCAAACGTCTCACCCTGTAAAAAGAGCGGCGCTGGCAATCAGCGCTGCTCC
ACCCGCTGCAGAAACCTTCG

Product: histidine kinase, HAMP region: chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 642; Mature: 642

Protein sequence:

>642_residues
MKSTWLDNLKVSKKLSVGFGLILLGVLTVTAIGYLSTNLLIERLGKAAKVSEVKADALSLRIAAQTYTAKPDASNSQGYT
SALDNLGKTIEDGLKILTVPVNADMLRGIRDQAGVLKQTFSQLVDNNRQIDQAMQPLITISEQVSGSFETLLQKTFDDVS
RSLDQSGIDQVKIAGDLRNGMTNFRLVFRRYISIPTAENRQITFDAADSLIAQVGSARNQLPNKAGPAVDEALAALQQYK
SLMVSISQLMQQNDQIRDSLRQQSMDIVTSAEKLMAGQVVSANKEKDSAVTQLLTVAVIVLLLGIFAAILITRQITRPLD
STVIAARRIADGDLTNDLSTTRQDELGLLQNTMQHMTVSLRTLIGGISNGVTQIATAAEELSAVSEQTSAGVTQQKLEVD
QVATAMNQMASTVQEVAQNTEDASQAARQASDRAAHGSSVVQHATREISQLAGEVGQLGEAMQRLIQDSDKIGGVIDVIK
AVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQSSTTEIEALIKSLQDGTGAASELMNASRQRTEGTVALA
RQAEESLLEITHSIVTIEQMSQQISAAAEEQSAVTDEINRSVISVRDIADQSATATEQSAASTVELARLGSNLQDMVARF
RI

Sequences:

>Translated_642_residues
MKSTWLDNLKVSKKLSVGFGLILLGVLTVTAIGYLSTNLLIERLGKAAKVSEVKADALSLRIAAQTYTAKPDASNSQGYT
SALDNLGKTIEDGLKILTVPVNADMLRGIRDQAGVLKQTFSQLVDNNRQIDQAMQPLITISEQVSGSFETLLQKTFDDVS
RSLDQSGIDQVKIAGDLRNGMTNFRLVFRRYISIPTAENRQITFDAADSLIAQVGSARNQLPNKAGPAVDEALAALQQYK
SLMVSISQLMQQNDQIRDSLRQQSMDIVTSAEKLMAGQVVSANKEKDSAVTQLLTVAVIVLLLGIFAAILITRQITRPLD
STVIAARRIADGDLTNDLSTTRQDELGLLQNTMQHMTVSLRTLIGGISNGVTQIATAAEELSAVSEQTSAGVTQQKLEVD
QVATAMNQMASTVQEVAQNTEDASQAARQASDRAAHGSSVVQHATREISQLAGEVGQLGEAMQRLIQDSDKIGGVIDVIK
AVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQSSTTEIEALIKSLQDGTGAASELMNASRQRTEGTVALA
RQAEESLLEITHSIVTIEQMSQQISAAAEEQSAVTDEINRSVISVRDIADQSATATEQSAASTVELARLGSNLQDMVARF
RI
>Mature_642_residues
MKSTWLDNLKVSKKLSVGFGLILLGVLTVTAIGYLSTNLLIERLGKAAKVSEVKADALSLRIAAQTYTAKPDASNSQGYT
SALDNLGKTIEDGLKILTVPVNADMLRGIRDQAGVLKQTFSQLVDNNRQIDQAMQPLITISEQVSGSFETLLQKTFDDVS
RSLDQSGIDQVKIAGDLRNGMTNFRLVFRRYISIPTAENRQITFDAADSLIAQVGSARNQLPNKAGPAVDEALAALQQYK
SLMVSISQLMQQNDQIRDSLRQQSMDIVTSAEKLMAGQVVSANKEKDSAVTQLLTVAVIVLLLGIFAAILITRQITRPLD
STVIAARRIADGDLTNDLSTTRQDELGLLQNTMQHMTVSLRTLIGGISNGVTQIATAAEELSAVSEQTSAGVTQQKLEVD
QVATAMNQMASTVQEVAQNTEDASQAARQASDRAAHGSSVVQHATREISQLAGEVGQLGEAMQRLIQDSDKIGGVIDVIK
AVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQSSTTEIEALIKSLQDGTGAASELMNASRQRTEGTVALA
RQAEESLLEITHSIVTIEQMSQQISAAAEEQSAVTDEINRSVISVRDIADQSATATEQSAASTVELARLGSNLQDMVARF
RI

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=534, Percent_Identity=28.2771535580524, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1787690, Length=346, Percent_Identity=31.5028901734104, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1788195, Length=332, Percent_Identity=33.7349397590361, Blast_Score=146, Evalue=3e-36,
Organism=Escherichia coli, GI1788194, Length=386, Percent_Identity=30.0518134715026, Blast_Score=139, Evalue=7e-34,
Organism=Escherichia coli, GI1789453, Length=357, Percent_Identity=30.5322128851541, Blast_Score=128, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 68746; Mature: 68746

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTWLDNLKVSKKLSVGFGLILLGVLTVTAIGYLSTNLLIERLGKAAKVSEVKADALSL
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RIAAQTYTAKPDASNSQGYTSALDNLGKTIEDGLKILTVPVNADMLRGIRDQAGVLKQTF
EEHHHHEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHH
SQLVDNNRQIDQAMQPLITISEQVSGSFETLLQKTFDDVSRSLDQSGIDQVKIAGDLRNG
HHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHH
MTNFRLVFRRYISIPTAENRQITFDAADSLIAQVGSARNQLPNKAGPAVDEALAALQQYK
HHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
SLMVSISQLMQQNDQIRDSLRQQSMDIVTSAEKLMAGQVVSANKEKDSAVTQLLTVAVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LLLGIFAAILITRQITRPLDSTVIAARRIADGDLTNDLSTTRQDELGLLQNTMQHMTVSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
RTLIGGISNGVTQIATAAEELSAVSEQTSAGVTQQKLEVDQVATAMNQMASTVQEVAQNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EDASQAARQASDRAAHGSSVVQHATREISQLAGEVGQLGEAMQRLIQDSDKIGGVIDVIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHH
AVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQSSTTEIEALIKSLQDGTG
HHHHHCCHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
AASELMNASRQRTEGTVALARQAEESLLEITHSIVTIEQMSQQISAAAEEQSAVTDEINR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVISVRDIADQSATATEQSAASTVELARLGSNLQDMVARFRI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
>Mature Secondary Structure
MKSTWLDNLKVSKKLSVGFGLILLGVLTVTAIGYLSTNLLIERLGKAAKVSEVKADALSL
CCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
RIAAQTYTAKPDASNSQGYTSALDNLGKTIEDGLKILTVPVNADMLRGIRDQAGVLKQTF
EEHHHHEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHH
SQLVDNNRQIDQAMQPLITISEQVSGSFETLLQKTFDDVSRSLDQSGIDQVKIAGDLRNG
HHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHH
MTNFRLVFRRYISIPTAENRQITFDAADSLIAQVGSARNQLPNKAGPAVDEALAALQQYK
HHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH
SLMVSISQLMQQNDQIRDSLRQQSMDIVTSAEKLMAGQVVSANKEKDSAVTQLLTVAVIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
LLLGIFAAILITRQITRPLDSTVIAARRIADGDLTNDLSTTRQDELGLLQNTMQHMTVSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
RTLIGGISNGVTQIATAAEELSAVSEQTSAGVTQQKLEVDQVATAMNQMASTVQEVAQNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EDASQAARQASDRAAHGSSVVQHATREISQLAGEVGQLGEAMQRLIQDSDKIGGVIDVIK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHH
AVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLAQRTQSSTTEIEALIKSLQDGTG
HHHHHCCHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCC
AASELMNASRQRTEGTVALARQAEESLLEITHSIVTIEQMSQQISAAAEEQSAVTDEINR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVISVRDIADQSATATEQSAASTVELARLGSNLQDMVARFRI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA